Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups

Journal of Biological Chemistry

Volumn 280, Issue 41, 2005, Pages 34420-34426

  Carmody, Maria ^a   Murphy, Barry ^a   Byrne, Barry ^a   Power, Patrick ^a   Rai, Dilip ^a   Rawlings, Bernard ^b   Caffrey, Patrick ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; DERIVATIVES; DISEASE CONTROL; FUNGI; IMMUNOLOGY; TOXICITY;

ANTIFUNGAL ACTIVITY; HEMOLYTIC ACTIVITY; IMMUNODEFICIENCY VIRUS; LIPOSOMAL FORMULATION;

BIOSYNTHESIS;

16 DESCARBOXYL 16 METHYL 19(O) (6 DEOXYHEXOSYL) 19(O) DESMYCOSAMINYLAMPHOTERICIN B; 16 DESCARBOXYL 16 METHYLAMPHOTERICIN B; 8 DEOXY 16 DESCARBOXYL 16 METHYL 19(O) (6 DEOXYHEXOSYL) 19(O) DESMYCOSAMINYLAMPHOTERICIN A; 8 DEOXY 16 DESCARBOXYL 16 METHYLAMPHOTERICIN A; AMPHOTERICIN; AMPHOTERICIN A; AMPHOTERICIN B; AMPHOTERICIN B METHYL ESTER; CARBOXYL GROUP; CYTOCHROME P450; UNCLASSIFIED DRUG;

AMPHN GENE; ANTIBIOTIC BIOSYNTHESIS; ANTIFUNGAL ACTIVITY; ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM MUTANT; CHEMICAL MODIFICATION; DRUG FORMULATION; DRUG STRUCTURE; GENE DELETION; HEMOLYSIS; HUMAN IMMUNODEFICIENCY VIRUS; LEISHMANIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRION DISEASE; PRIORITY JOURNAL; STREPTOMYCES; STREPTOMYCES NODOSUS;

AMPHOTERICIN B; ANTIBIOTICS, ANTIFUNGAL; BACTERIOPHAGES; CARBON; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; ESCHERICHIA COLI; GENE DELETION; LIPOSOMES; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MODELS, CHEMICAL; MULTIGENE FAMILY; MUTATION; POLYENES; PROTEIN STRUCTURE, TERTIARY; RECOMBINATION, GENETIC; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STREPTOMYCES;

BACTERIA (MICROORGANISMS); FUNGI; HUMAN IMMUNODEFICIENCY VIRUS; STREPTOMYCES; STREPTOMYCES NODOSUS;

EID: 26944438216     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M506689200     Document Type: Article

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