Effect of amphotericin B on wild-type and mutated prion proteins in cultured cells: Putative mechanism of action in transmissible spongiform encephalopathies

Journal of Neurochemistry

Volumn 74, Issue 2, 2000, Pages 754-762

  Mangé, Alain ^a   Milhavet, Ollivier ^a   McMahon, Hilary E M ^a   Casanova, Danielle ^a   Lehmann, Sylvain ^a  

^a INSTITUTE OF HUMAN GENETICS   (France)

Author keywords

Amphotericin B; Prion protein; Transmissible spongiform encephalopathies

Indexed keywords

AMPHOTERICIN B; GLYCOSYLPHOSPHATIDYLINOSITOL; MUTANT PROTEIN; PRION PROTEIN;

ANIMAL CELL; ARTICLE; BRAIN SPONGIOSIS; CELL CULTURE; CONFORMATIONAL TRANSITION; DISEASE TRANSMISSION; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; GENE MUTATION; GENETIC TRANSFECTION; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE;

AMPHOTERICIN B; ANIMALS; CHO CELLS; CRICETINAE; DETERGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; MICE; MICE, INBRED STRAINS; MUTATION; PRION DISEASES; PRIONS; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 0033964470     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.740754.x     Document Type: Article

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