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Volumn 4, Issue , 2005, Pages

Inactivation of MAP kinase signalling in Myc transformed cells and rescue by LiCl inhibition of GSK3

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3; LITHIUM CHLORIDE; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; ONCOPROTEIN;

EID: 26844570606     PISSN: 14764598     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-4-13     Document Type: Article
Times cited : (3)

References (38)
  • 1
    • 0037630079 scopus 로고    scopus 로고
    • Reconstructing MYC
    • Levens DL: Reconstructing MYC. Genes Dev 2003, 17:1071-1077.
    • (2003) Genes Dev. , vol.17 , pp. 1071-1077
    • Levens, D.L.1
  • 2
    • 0033551374 scopus 로고    scopus 로고
    • MYC oncogenes and human neoplastic disease
    • Nesbit CE, Tersak JM, Prochownik EV: MYC oncogenes and human neoplastic disease. Oncogene 1999, 18:3004-3016.
    • (1999) Oncogene , vol.18 , pp. 3004-3016
    • Nesbit, C.E.1    Tersak, J.M.2    Prochownik, E.V.3
  • 3
    • 0030933277 scopus 로고    scopus 로고
    • Oncoprotein networks
    • Hunter T: Oncoprotein networks. Cell 1997, 88:333-346.
    • (1997) Cell , vol.88 , pp. 333-346
    • Hunter, T.1
  • 6
    • 0037197962 scopus 로고    scopus 로고
    • Characterization of the c-MYC-regulated transcriptome by SAGE: Identification and analysis of c-MYC target genes
    • Menssen A, Hermeking H: Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes. Proc Natl Acad Sci U S A 2002, 99:6274-6279.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 6274-6279
    • Menssen, A.1    Hermeking, H.2
  • 7
    • 0025763419 scopus 로고
    • Max: A helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc
    • Blackwood EM, Eisenman RN: Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science 1991, 251:1211-1217.
    • (1991) Science , vol.251 , pp. 1211-1217
    • Blackwood, E.M.1    Eisenman, R.N.2
  • 8
    • 0026665523 scopus 로고
    • Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max
    • Amati B, Dalton S, Brooks MW, Littlewood TD, Evan GI, Land H: Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max. Nature 1992, 359:423-426.
    • (1992) Nature , vol.359 , pp. 423-426
    • Amati, B.1    Dalton, S.2    Brooks, M.W.3    Littlewood, T.D.4    Evan, G.I.5    Land, H.6
  • 9
    • 0025829169 scopus 로고
    • Association of Myn, the murine homolog of max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation
    • Prendergast GC, Lawe D, Ziff EB: Association of Myn, the murine homolog of max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation. Cell 1991, 65:395-407.
    • (1991) Cell , vol.65 , pp. 395-407
    • Prendergast, G.C.1    Lawe, D.2    Ziff, E.B.3
  • 10
    • 3543060464 scopus 로고    scopus 로고
    • Myc boxes, which are conserved in myc family proteins, are signals for protein degradation via the proteasome
    • Flinn EM, Busch CM, Wright AP: myc boxes, which are conserved in myc family proteins, are signals for protein degradation via the proteasome. Mol Cell Biol 1998, 18:5961-5969.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 5961-5969
    • Flinn, E.M.1    Busch, C.M.2    Wright, A.P.3
  • 11
    • 0032905924 scopus 로고    scopus 로고
    • c-Myc target genes involved in cell growth, apoptosis, and metabolism
    • Dang CV: c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol 1999, 19:1-11.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 1-11
    • Dang, C.V.1
  • 12
    • 0028023421 scopus 로고
    • Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis
    • Lutterbach B, Hann SR: Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis. Mol Cell Biol 1994, 14:5510-5522.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 5510-5522
    • Lutterbach, B.1    Hann, S.R.2
  • 13
    • 0033559270 scopus 로고    scopus 로고
    • c-Myc transactivation domain-associated kinases: Questionable role for map kinases in c-Myc phosphorylation
    • Lutterbach B, Hann SR: c-Myc transactivation domain-associated kinases: questionable role for map kinases in c-Myc phosphorylation. J Cell Biochem 1999, 72:483-491.
    • (1999) J. Cell Biochem. , vol.72 , pp. 483-491
    • Lutterbach, B.1    Hann, S.R.2
  • 14
    • 0037542854 scopus 로고    scopus 로고
    • Ras proteins: Different signals from different locations
    • Hancock JF: Ras proteins: different signals from different locations. Nat Rev Mol Cell Biol 2003, 4:373-384.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 373-384
    • Hancock, J.F.1
  • 15
    • 0034643380 scopus 로고    scopus 로고
    • R-Ras3, a brain-specific Rasrelated protein, activates Akt and promotes cell survival in PC12 cells
    • Kimmelman AC, Osada M, Chan AM: R-Ras3, a brain-specific Rasrelated protein, activates Akt and promotes cell survival in PC12 cells. Oncogene 2000, 19:2014-2022.
    • (2000) Oncogene , vol.19 , pp. 2014-2022
    • Kimmelman, A.C.1    Osada, M.2    Chan, A.M.3
  • 16
    • 0032508517 scopus 로고    scopus 로고
    • Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase
    • Yan J, Roy S, Apolloni A, Lane A, Hancock JF: Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase. J Biol Chem 1998, 273:24052-24056.
    • (1998) J. Biol. Chem. , vol.273 , pp. 24052-24056
    • Yan, J.1    Roy, S.2    Apolloni, A.3    Lane, A.4    Hancock, J.F.5
  • 17
    • 0033546419 scopus 로고    scopus 로고
    • Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility
    • Voice JK, Klemke RL, Le A, Jackson JH: Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility. J Biol Chem 1999, 274:17164-17170.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17164-17170
    • Voice, J.K.1    Klemke, R.L.2    Le, A.3    Jackson, J.H.4
  • 21
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang L, Karin M: Mammalian MAP kinase signalling cascades. Nature 2001, 410:37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 22
    • 0035869396 scopus 로고    scopus 로고
    • Cell-cycle-dependent activation of mitogen-activated protein kinase kinase (MEK-1/2) in myeloid leukemia cell lines and induction of growth inhibition and apoptosis by inhibitors of RAS signaling
    • Morgan MA, Dolp O, Reuter CW: Cell-cycle-dependent activation of mitogen-activated protein kinase kinase (MEK-1/2) in myeloid leukemia cell lines and induction of growth inhibition and apoptosis by inhibitors of RAS signaling. Blood 2001, 97:1823-1834.
    • (2001) Blood , vol.97 , pp. 1823-1834
    • Morgan, M.A.1    Dolp, O.2    Reuter, C.W.3
  • 23
    • 0042744812 scopus 로고    scopus 로고
    • MEK/ERK pathway is aberrantly active in Hodgkin disease: A signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival
    • Zheng B, Fiumara P, Li YV, Georgakis G, Snell V, Younes M, Vauthey JN, Carbone A, Younes A: MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival. Blood 2003, 102:1019-1027.
    • (2003) Blood , vol.102 , pp. 1019-1027
    • Zheng, B.1    Fiumara, P.2    Li, Y.V.3    Georgakis, G.4    Snell, V.5    Younes, M.6    Vauthey, J.N.7    Carbone, A.8    Younes, A.9
  • 24
    • 0034660524 scopus 로고    scopus 로고
    • Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src
    • Fincham VJ, James M, Frame MC, Winder SJ: Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src. Embo J 2000, 19:2911-2923.
    • (2000) Embo. J. , vol.19 , pp. 2911-2923
    • Fincham, V.J.1    James, M.2    Frame, M.C.3    Winder, S.J.4
  • 25
    • 0032959647 scopus 로고    scopus 로고
    • Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis
    • Treinies I, Paterson HF, Hooper S, Wilson R, Marshall CJ: Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis. Mol Cell Biol 1999, 19:321-329.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 321-329
    • Treinies, I.1    Paterson, H.F.2    Hooper, S.3    Wilson, R.4    Marshall, C.J.5
  • 26
    • 0029130410 scopus 로고
    • Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes
    • McCarthy SA, Samuels ML, Pritchard CA, Abraham JA, McMahon M: Rapid induction of heparin-binding epidermal growth factor/ diphtheria toxin receptor expression by Raf and Ras oncogenes. Genes Dev 1995, 9:1953-1964.
    • (1995) Genes Dev. , vol.9 , pp. 1953-1964
    • McCarthy, S.A.1    Samuels, M.L.2    Pritchard, C.A.3    Abraham, J.A.4    McMahon, M.5
  • 27
    • 0034100567 scopus 로고    scopus 로고
    • v-Jun overrides the mitogen dependence of Sphase entry by deregulating retinoblastoma protein phosphorylation and E2F-pocket protein interactions as a consequence of enhanced cyclin E-cdk2 catalytic activity
    • Clark W, Black EJ, MacLaren A, Kruse U, LaThangue N, Vogt PK, Gillespie DA: v-Jun overrides the mitogen dependence of Sphase entry by deregulating retinoblastoma protein phosphorylation and E2F-pocket protein interactions as a consequence of enhanced cyclin E-cdk2 catalytic activity. Mol Cell Biol 2000, 20:2529-2542.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 2529-2542
    • Clark, W.1    Black, E.J.2    MacLaren, A.3    Kruse, U.4    LaThangue, N.5    Vogt, P.K.6    Gillespie, D.A.7
  • 28
    • 0037853146 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 beta is a natural activator of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1)
    • Kim JW, Lee JE, Kim MJ, Cho EG, Cho SG, Choi EJ: Glycogen synthase kinase 3 beta is a natural activator of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1). J Biol Chem 2003, 278:13995-14001.
    • (2003) J. Biol. Chem. , vol.278 , pp. 13995-14001
    • Kim, J.W.1    Lee, J.E.2    Kim, M.J.3    Cho, E.G.4    Cho, S.G.5    Choi, E.J.6
  • 29
    • 0037147327 scopus 로고    scopus 로고
    • ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons
    • Hetman M, Hsuan SL, Habas A, Higgins MJ, Xia Z: ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons. J Biol Chem 2002, 277:49577-49584.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49577-49584
    • Hetman, M.1    Hsuan, S.L.2    Habas, A.3    Higgins, M.J.4    Xia, Z.5
  • 30
    • 0029922539 scopus 로고    scopus 로고
    • Comparative analysis of the structure and function of the chicken c-myc and v-myc genes: v-myc is a more potent inducer of cell proliferation and apoptosis than c-myc
    • Petropoulos CJ, Givol I, Hughes SH: Comparative analysis of the structure and function of the chicken c-myc and v-myc genes: v-myc is a more potent inducer of cell proliferation and apoptosis than c-myc. Oncogene 1996, 12:2611-2621.
    • (1996) Oncogene , vol.12 , pp. 2611-2621
    • Petropoulos, C.J.1    Givol, I.2    Hughes, S.H.3
  • 31
    • 0033551399 scopus 로고    scopus 로고
    • The v-myc oncogene
    • Lee CM, Reddy EP: The v-myc oncogene. Oncogene 1999, 18:2997-3003.
    • (1999) Oncogene , vol.18 , pp. 2997-3003
    • Lee, C.M.1    Reddy, E.P.2
  • 32
    • 0034677804 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium
    • Bijur GN, De Sarno P, Jope RS: Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium. J Biol Chem 2000, 275:7583-7590.
    • (2000) J. Biol. Chem. , vol.275 , pp. 7583-7590
    • Bijur, G.N.1    De Sarno, P.2    Jope, R.S.3
  • 33
    • 0031973597 scopus 로고    scopus 로고
    • Repression of mitogen-activated protein kinases ERK1/ERK2 activity by a protein tyrosine phosphatase in rat fibroblasts transformed by upstream oncoproteins
    • Gopalbhai K, Meloche S: Repression of mitogen-activated protein kinases ERK1/ERK2 activity by a protein tyrosine phosphatase in rat fibroblasts transformed by upstream oncoproteins. J Cell Physiol 1998, 174:35-47.
    • (1998) J. Cell Physiol. , vol.174 , pp. 35-47
    • Gopalbhai, K.1    Meloche, S.2
  • 34
    • 0037136696 scopus 로고    scopus 로고
    • Cell transformation by v-Jun deactivates ERK MAP kinase signalling
    • Black EJ, Walker M, Clark W, MacLaren A, Gillespie DA: Cell transformation by v-Jun deactivates ERK MAP kinase signalling. Oncogene 2002, 21:6540-6548.
    • (2002) Oncogene , vol.21 , pp. 6540-6548
    • Black, E.J.1    Walker, M.2    Clark, W.3    MacLaren, A.4    Gillespie, D.A.5
  • 35
    • 0347695988 scopus 로고    scopus 로고
    • Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization
    • Gregory MA, Qi Y, Hann SR: Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization. J Biol Chem 2003, 278:51606-51612.
    • (2003) J. Biol. Chem. , vol.278 , pp. 51606-51612
    • Gregory, M.A.1    Qi, Y.2    Hann, S.R.3
  • 36
    • 0034306997 scopus 로고    scopus 로고
    • Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
    • Sears R, Nuckolls F, Haura E, Taya Y, Tamai K, Nevins JR: Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev 2000, 14:2501-2514.
    • (2000) Genes Dev. , vol.14 , pp. 2501-2514
    • Sears, R.1    Nuckolls, F.2    Haura, E.3    Taya, Y.4    Tamai, K.5    Nevins, J.R.6
  • 37
    • 0028037187 scopus 로고
    • c-Myc inhibits myogenic differentiation and myoD expression by a mechanism which can be dissociated from cell transformation
    • La Rocca SA, Crouch DH, Gillespie DA: c-Myc inhibits myogenic differentiation and myoD expression by a mechanism which can be dissociated from cell transformation. Oncogene 1994, 9:3499-3508.
    • (1994) Oncogene , vol.9 , pp. 3499-3508
    • La Rocca, S.A.1    Crouch, D.H.2    Gillespie, D.A.3
  • 38
    • 0033539925 scopus 로고    scopus 로고
    • Protein stabilization: A common consequence of mutations in independently derived v-Myc alleles
    • Gavine PR, Neil JC, Crouch DH: Protein stabilization: a common consequence of mutations in independently derived v-Myc alleles. Oncogene 1999, 18:7552-7558.
    • (1999) Oncogene , vol.18 , pp. 7552-7558
    • Gavine, P.R.1    Neil, J.C.2    Crouch, D.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.