c-Myc transactivation domain-associated kinases: Questionable role for map kinases in c-Myc phosphorylation

Journal of Cellular Biochemistry

Volumn 72, Issue 4, 1999, Pages 483-491

  Lutterbach, Bart ^a   Hann, Stephen R ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

c Myc; Kinases; Phosphorylation

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME ISOLATION; ENZYME PHOSPHORYLATION; MOUSE; NONHUMAN; ONCOGENE C MYC; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN DOMAIN; TRANSACTIVATION;

3T3 CELLS; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; COS CELLS; MICE; PHOSPHOPEPTIDES; PHOSPHORYLATION; PHOSPHOSERINE; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-MYC; TETRADECANOYLPHORBOL ACETATE;

EID: 0033559270     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19990315)72:4<483::AID-JCB4>3.0.CO;2-I     Document Type: Article

References (32)

1. Bhatia K, Huppi K, Spangler G, Siwarski D, Iyer R, Magrath I. 1993. Point mutations in the c-Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytoma. Nature Gen 5:56-61.
2. Boulton TG, Nye DJ, Robbing NY, Ip E, Radziewjewska SD, Morganbesser SD, DePinho RA, Panayotatos N, Cobb MH, Yancopoulos GD. 1991. ERKs: A family of protein-serine/threonin kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell 65:663-675.
3. Boyle WJ, van der Greer P, Hunter T. 1991. Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol 201:110-149.
4. Chen C, Biegalke BJ, Eisenman RN, Linial ML. 1989. FH3, a v-myc avian retrovirus with limited transforming ability, J Virol 63:5092-5100.
5. Ely CM, Oddie KM, Litz JS, Rossomaondo A, Kanner SB, Strugill TW, Parsons SJ. 1990. A 42 kd tyrosine kinase substrate linked to chromaffin cell sectetion exhibits an associated MAP kinase activity and is highly related to a 42 kd mitogen stimulated protein in fibroblasts. J Cell Biol 110:731-742.
6. Frykberg L, Graf T, Vennstrom B. 1987. The transforming activity of the chicken c-Myc gene can be potentiated by mutations. Oncogene 1:415-421.
7. Gaubatz S, Imhof A, Dosch R, Werner O, Mitchell P, Buettner R, Eilers M. 1995. Transcriptional activation by Myc is under negative control by the transcription factor AP-2. EMBOJ 14:1508-1519.
8. Gupta S, Campbell D, Derijard B, Davis RJ. 1995. Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267:389-393.
9. 2-terminal activation domain of c-Myc. FEBS Lett 353:281-285.
10. Hann SR, Abrams HD, Rohrschneider LR, Eisenman RN. 1983. Proteins encoded by v-Myc and c-Myc oncogenes: Identification and localization in acute leukemia transformants and bursal lymphoma cell lines. Cell 34:789-798.
11. Henricksson M, Bakardjiev A, Klein G, Luscher B. 1993. Phosphorylation sites mapping in the N-terminal domain of c-Myc modulate its transforming potential. Oncogene 8:3199-3209.
12. Hibi M, Lin A, Smeal T, Minden A, Karin M. 1993. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation doamin. Genes Dev 7:2135-2148.
13. Hoang A, Lutterbach B, Lewis BC, Yano T, Chou T-Y, Barrett J, Raffeld M, Hann SR, Dang CV. 1995. A link between increased transforming activity of lymphomaderived MYC mutant alleles, their defective regulation by p 107, and altered phosphorylation of the c-Myc transactivation domain. Mol Cell Biol 15:4031-4042.
14. Hunter T, Karin M. 1992. The regulation of transcription by phosphorylation. Cell 70:375-387.
15. Kameshita I, Fujisawa H. 1989. A sensitive method for detection of calmodulin-dependent protein kinase II in sodium dodecyl sulfate-polyacrylamide gel. Anal Biochem 183:139-143.
16. Kazlauskas A, Cooper JA. 1988. Protein kinaase C mediates platelet-derived growth factor-induced tyrosine phosphorylation of p42. J Cell Biol 106:1395-1402.
17. Kunkel TA. 1985. Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc Natl Acad Sci USA 82:488-492.
18. Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahamd MF, Avruch J, Woodgett JR. 1994. The stress-activated protein kinase subfamily of kinases. Nature 369:156-160.
19. Luscher B, Kuenzel EA, Krebs EG, Eisenman RN. 1989. Myc proteins are phosphorylated by casein kinase II. EMBO J 8:1111-1119.
20. Lutterbach B, Hann SR. 1997. Overexpression of c-Myc and cell immortalization alters c-Myc phosphorylation. Oncogene 14:967-975.
21. Lutterbach B, Hann SR. 1994. Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis. Mol Cell Biol 14:5510-5522.
22. Meek DW, Street AJ. 1992. Nuclear protein phosphorylation and growth control. Biochem J 287:1-15.
23. Palmieri S, Kahn P, Graf T. 1983. Quail embryo fibroblasts transformed by four v-myc isolates show enhanced proliferation but are non-tumorigenic. EMBO J 2:2385-2389.
24. Papas TS, Lautenberger JA. 1985. Sequence curiosity in v-myc oncogene. Nature 318:237.
25. Pulverer BJ, Fischer K, Vousden K, Littlewood T, Evan G, Woodgett JR. 1994. Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo. Oncogene 9:59-70.
26. Rossomando AJ, Payne DM, Weber MJ, Pelech SL, Sturgill TW. 1989. Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase. Proc Natl Acad Sci USA 86:6940-6943.
27. Seth A, Gonzalez S, Gupta S, Raden DL, Davis RJ. 1992. Signal transduction within the nucleus by mitogen activated protein kinase. J Biol Chem 267:24796-24804.
28. Sherr CJ. 1994. G1 phase progression: Cycling on cue. Cell 79:551-555.
29. Smeal T, Binetruy B, Mercola D, Grover-Bardwick A, Heidecker G, Rapp UR, Karin M. 1992. Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73. Mol Cell Biol 12: 3507-3513.
30. Smith D, Johnson K. 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67:31-40.
31. Street AJ, Blackwood E, Luscher B, Eisenman RN. 1990. Mutational analysis of the carboxy-terminal casein kinase II phosphorylation site in human c-myc. Curr Top Microbiol Immunol 166:251-258.
32. Symonds G, Hartshorn A, Kennewell A, O'Mara M-A, Bruskin A, Bishop JM. 1989. Transformation of murine myelomonocytic cells by myc: Point mutations in v-myc contribute synergistically to transforming potential. Oncogene 4:285-294.