E3B1, a human homologue of the mouse gene product Abi-1, sensitizes activation of Rap1 in response to epidermal growth factor

Experimental Cell Research

Volumn 310, Issue 2, 2005, Pages 463-473

  Jenei, Veronika ^a   Andersson, Tommy ^b   Jakus, Judit ^a   Dib, Karim ^b,c  

^a CHEMICAL RESEARCH CENTER   (Hungary)

^b LUND UNIVERSITY   (Sweden)

^c QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

C3G; E3B1; EGF receptor; Rac; Rap1; Src tyrosine kinase

Indexed keywords

ABELSON KINASE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GENE PRODUCT; GUANOSINE TRIPHOSPHATASE; ISOPROTEIN; PROTEIN ABL INTERACTOR 1; PROTEIN E3B1; PROTEIN P21; PROTEIN TYROSINE KINASE; RAC1 PROTEIN; RAP PROTEIN; RAP1 PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SEQUENCE HOMOLOGY;

EID: 26844567358     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2005.08.010     Document Type: Article

References (38)

1. G.P. Cowley, J.A. Smith, and A. Gusterson Increased EGF receptor on human squamous carcinoma cell lines Br. J. Cancer 53 1986 223 229
2. M.E. Noble, J.A. Endicott, and L. Johnson Protein kinase inhibitors: insight into drug design from structure Science 303 2004 1800 1805
3. J. Schlessinger Cell signaling by receptor tyrosine kinases Cell 103 2000 193 200
4. J. Schlessinger Ligand-induced, receptor-mediated dimerization and activation of EGF receptor Cell 110 2002 669 672
5. V.J. Finchman, M. Unlu, V.G. Brunton, J.D. Pitts, J.A. Wyke, and M.C. Frame Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins J. Cell Biol. 135 1996 1551 1564
6. J.S. Biscardi, M.C. Maa, D.A. Tice, M.E. Cox, T.H. Leu, and S.J. Parsons c-Src-mediated phosphorylation of the epidermal growth factor on Tyr845 and Tyr1101 is associated with modulation of receptor function J. Biol. Chem. 274 1999 8335 8343
7. R. Plattner, L. Kadlec, K.A. DeMali, A. Kazlauskas, and A.M. Pendergast c-Abl is activated by growth factors and Src family tyrosine kinases and has a role in the cellular response to PDGF Genes Dev. 13 1999 2400 2411
8. M.S. Boguski, and F. McCormick Proteins regulating Ras and its relatives Nature 366 1993 643 654
9. A.B. Vojtek, S.M. Hollenberg, and J.A. Cooper Mammalian Ras interacts directly with the serine/threonine kinase Raf Cell 74 1993 205 214
10. A. Hall Rho GTPases and the actin cytoskeleton Science 279 1998 509 514
11. Y. Shi, K. Alin, and S.P. Goff Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity Genes Dev. 9 1995 2583 2597
12. Z. Biesova, C. Piccoli, and W.T. Wong Isolation and characterization of E3B1, an eps8 binding protein that regulates cell growth Oncogene 14 1997 233 241
13. M. Innocenti, P. Tenca, E. Frittoli, M. Faretta, A. Tocchetti, P.P. Di Fiore, and G. Scita Mechanisms through which Sos-1 coordinates the activation of Ras and Rac J. Cell Biol. 156 2002 125 136
14. M. Innocenti, E. Frittoli, I. Ponzanelli, J.R. Falck, S.M. Brachmann, P.P. Di Fiore, and G. Scita Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1 J. Cell Biol. 160 2003 17 23
15. A. Ikeguchi, H.Y. Yang, G. Gao, and S.P. Goff Inhibition of v-Abl transformation in 3T3 cells overexpressing different forms of the Abelson interactor protein Abi-1 Oncogene 20 2001 4926 4934
16. H. Kitayama, Y. Sugimoto, T. Matsuzaki, Y. Ikawa, and M. Noda A ras-related gene with transformation suppressor activity Cell 56 1989 77 84
17. N.J. D'Silva, R.S. Mitra, Z. Zhang, D.M. Kurnit, C.R. Babcock, P.J. Polverini, and T.E. Carey Rap1, a small GTP-binding protein is upregulated during arrest of proliferation in human keratinocytes J. Cell. Physiol. 196 2003 532 540
18. A.J. Apicelli, E.J. Uhlmann, R.L. Baldwin, H. Ding, A. Nagy, A. Guha, and D.H. Gutmann Role of the Rap1 GTPase in astrocyte growth regulation Glia 42 2003 225 234
19. J.M. Schmitt, and P.J. Stork PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1 Mol. Cell 9 2002 85 94
20. L.S. Price, A. Hajdo-Milasinovic, J. Zhao, F.J. Zwartkruis, J.G. Collard, and J.L. Bos Rap1 regulates E-cadherin-mediated cell-cell adhesion J. Biol. Chem. 279 2004 35127 35132
21. T. Fukuyama, H. Ogita, T. Kawakatsu, T. Fukuhara, T. Yamada, T. Sato, K. Shimizu, T. Nakamura, M. Matsuda, and Y. Takai Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions J. Biol. Chem. 280 2005 815 825
22. J.H. Hanke, J.P. Garden, R.L. Dow, P.S. Changelian, W.H. Brissette, E.J. Weringer, B.A. Pollok, and P.A. Connelly Discovery of a novel, potent, and src family-selective tyrosine kinase inhibitor J. Biol. Chem. 271 1996 695 701
23. P.P. Di Fiore, J.H. Pierce, T.P. Fleming, R. Hazan, A. Ullrich, C.R. King, J. Schlessinger, and S.A. Aaronson Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells Cell 51 1987 1063 1070
24. S. Edlund, M. Landström, C.H. Heldin, and P. Aspenström Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA Mol. Biol. Cell 13 2002 902 914
25. L. M'Rabet, P. Coffer, F. Zwartkruis, B. Franke, A.W. Segal, L. Koenderman, and J.L. Bos Activation of the small GTPase Rap1 in human neutrophils Blood 92 1998 2133 2140
26. B. Hallberg, S.I. Rayter, and J. Downward Interaction of Ras and Raf in intact mammalian cells upon extracellular stimulation J. Biol. Chem. 269 1994 3913 3916
27. W. Schaffner, and C. Weissmann A rapid, sensitive, and specific method for the determination of protein in dilute solution Anal. Biochem. 56 1973 502 514
28. K. Dib, F. Melander, L. Axelsson, M-C. Dagher, P. Aspenström, and T. Andersson Down-regulation of Rac activity during β2 integrin-mediated adhesion of human neutrophils J. Biol. Chem. 278 2003 24181 24188
29. Y. Obara, K. Labudda, T.J. Dillon, and P.J.S. Stork PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells J. Cell Sci. 117 2004 6085 6094
30. J. Waltenberger, A. Uecker, J. Kroll, H. Frank, U. Mayr, J.D. Bjorge, D. Fujita, A. Gazit, V. Hombach, A. Levitzky, and F.D. Bohmer A dual inhibitor of platelet-derived growth factor beta-receptor and Src kinase activity potently interferes with motogenic and mitogenic responses to PDGF in vascular smooth muscle cells. A novel candidate for prevention of vascular remodeling Circ. Res. 85 1999 12 22
31. R.A. Blake, M.A. Broome, X. Liu, J. Wu, M. Gishizky, L. Sun, and S.A. Courtneidge SU6656, a selective Src family kinase inhibitor, used to probe growth factor signalling Mol. Cell. Biol. 20 2000 9018 9027
32. E. Buchdunger, J. Zimmermann, H. Mett, T. Meyer, M. Muller, B.J. Druker, and N.B. Lydon Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative Cancer Res. 56 1996 100 104
33. L. Tatton, G.M. Morley, R. Chopra, and A. Khwaja The Src-selective kinase inhibitor PP1 also inhibits Kit and Bcr-Abl tyrosine kinases J. Biol. Chem. 278 2003 4847 4853
34. L. Ling, T. Zhu, and P.E. Lobie Src-CrkII-C3G-dependent activation of Rap1 switches growth hormone-stimulated p44/42 MAP kinase and JNK/SAPK activities J. Biol. Chem. 278 2003 27301 27311
35. T. Ichiba, Y. Hashimoto, M. Nakaya, Y. Kuraishi, S. Tanaka, T. Kurata, N. Mochizuki, and M. Matsuda Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504 J. Biol. Chem. 274 1999 14376 14381
36. P.D. Fan, and S.P. Goff Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinases Mol. Cell. Biol. 20 2000 7591 7601
37. M.J.J. Frech, V. Pizon, P. Chardin, A. Tavitian, R. Clark, F. McCormick, and A. Wittinghofer Inhibition of GTPase activating protein stimulation of ras-p21GTPase by the Krev-1 gene product Science 249 1990 169 171
38. D. Mizuchi, T. Kurosu, A. Kida, Z.H. Jin, A. Jin, A. Arai, and O. Miura BCR/ABL activates Rap1 and B-Raf to stimulate the MEK/Erk signaling pathway in hematopoietic cells Biochem. Biophys. Res. Commun. 326 2005 645 651