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Volumn 9, Issue 5, 1996, Pages 587-597

Global inhibition of IL-2 and IFN-γ secreting T cells precedes recovery from acute monophasic experimental autoimmune encephalomyelitis

Author keywords

Autoimmune; Cytokine; Encephalomyelitis; Lymphocyte; Multiple sclerosis

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4;

EID: 0030272108     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1006/jaut.1996.0078     Document Type: Article
Times cited : (13)

References (59)
  • 2
    • 0023663430 scopus 로고
    • T cell tolerance by clonal elimination in the thymus
    • 2. Kappler J.W., Roehm N., Marrack P. 1987. T cell tolerance by clonal elimination in the thymus. Cell 49: 273-280
    • (1987) Cell , vol.49 , pp. 273-280
    • Kappler, J.W.1    Roehm, N.2    Marrack, P.3
  • 5
    • 0025602793 scopus 로고
    • Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity
    • 5. Webb S., Morris C., Sprent J. 1990. Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity. Cell 63: 1249-1256
    • (1990) Cell , vol.63 , pp. 1249-1256
    • Webb, S.1    Morris, C.2    Sprent, J.3
  • 7
    • 0025075249 scopus 로고
    • Alterations in T cell antigen specificity and class II restriction during the course of chronic relapsing experimental allergic encephalomyelitis
    • 7. McCarron R.M., Fallis R.J., McFarlin D.E. 1990. Alterations in T cell antigen specificity and class II restriction during the course of chronic relapsing experimental allergic encephalomyelitis. J. Neuroimmunol. 29: 73-79
    • (1990) J. Neuroimmunol. , vol.29 , pp. 73-79
    • McCarron, R.M.1    Fallis, R.J.2    McFarlin, D.E.3
  • 8
    • 0026664422 scopus 로고
    • Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen
    • 8. Lehmann P.V., Forsthuber T., Miller A., Sercarz E.E. 1992. Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature 358: 155-157
    • (1992) Nature , vol.358 , pp. 155-157
    • Lehmann, P.V.1    Forsthuber, T.2    Miller, A.3    Sercarz, E.E.4
  • 9
    • 0027403782 scopus 로고
    • Development of reactivity to new myelin antigens during chronic relapsing autoimmune demyelination
    • 9. Cross A.H., Tuohy V.K., Raine C.S. 1993. Development of reactivity to new myelin antigens during chronic relapsing autoimmune demyelination. Cell. Immunol. 146: 261-269
    • (1993) Cell. Immunol. , vol.146 , pp. 261-269
    • Cross, A.H.1    Tuohy, V.K.2    Raine, C.S.3
  • 10
    • 0029000750 scopus 로고
    • Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis
    • 10. McRae B.L., Vanderlugt C.L., Dal C.M., Miller S.D. 1995. Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis. J. Exp. Med. 182: 75-85
    • (1995) J. Exp. Med. , vol.182 , pp. 75-85
    • McRae, B.L.1    Vanderlugt, C.L.2    Dal, C.M.3    Miller, S.D.4
  • 11
    • 0027318299 scopus 로고
    • Diverse T cell receptor V beta gene usage in the central nervous system in experimental allergic encephalomyelitis
    • 11. Bell R.B., Lindsey J.W., Sobel R.A., Hodgkinson S., Steinman L. 1993. Diverse T cell receptor V beta gene usage in the central nervous system in experimental allergic encephalomyelitis. J. Immunol. 150: 4085-4092
    • (1993) J. Immunol. , vol.150 , pp. 4085-4092
    • Bell, R.B.1    Lindsey, J.W.2    Sobel, R.A.3    Hodgkinson, S.4    Steinman, L.5
  • 12
    • 0027196705 scopus 로고
    • Selective and nonselective stages in homing of T lymphocytes to the central nervous system during experimental allergic encephalomyelitis
    • 12. Karin N., Szafer F., Mitchell D., Gold D.P., Steinman L. 1993. Selective and nonselective stages in homing of T lymphocytes to the central nervous system during experimental allergic encephalomyelitis. J. Immunol. 150: 4116-4124
    • (1993) J. Immunol. , vol.150 , pp. 4116-4124
    • Karin, N.1    Szafer, F.2    Mitchell, D.3    Gold, D.P.4    Steinman, L.5
  • 13
    • 0027293755 scopus 로고
    • Where, when, and how to detect biased expression of disease-relevant V beta genes in rats with experimental autoimmune encephalomyelitis
    • 13. Offner H., Buenafe A.C., Vainiene M., Celnik B., Weinberg A.D., Gold D.P., Hashim G., Vandenbark A.A. 1993. Where, when, and how to detect biased expression of disease-relevant V beta genes in rats with experimental autoimmune encephalomyelitis. J. Immunol. 151: 506-517
    • (1993) J. Immunol. , vol.151 , pp. 506-517
    • Offner, H.1    Buenafe, A.C.2    Vainiene, M.3    Celnik, B.4    Weinberg, A.D.5    Gold, D.P.6    Hashim, G.7    Vandenbark, A.A.8
  • 14
    • 0025290312 scopus 로고
    • Heterogeneity of mouse helper T cells. Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells
    • 14. Street N.E., Schumacher J.H., Fong T.A., Bass H., Florentine D.F., Leverah J.A., Mosmann T.R. 1990. Heterogeneity of mouse helper T cells. Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells. J. Immunol. 144: 1629-1639
    • (1990) J. Immunol. , vol.144 , pp. 1629-1639
    • Street, N.E.1    Schumacher, J.H.2    Fong, T.A.3    Bass, H.4    Florentine, D.F.5    Leverah, J.A.6    Mosmann, T.R.7
  • 15
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • 15. Mosmann T.R., Cherwinski H., Bond M.W., Giedlin M.A., Coffman R.L. 1986. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136: 2348-2357
    • (1986) J. Immunol. , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 16
    • 0024357498 scopus 로고
    • Antiproliferative effect of IFN-gamma in immune regulation. III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-gamma
    • 16. Gajewski T.F., Joyce J., Fitch F.W. 1989. Antiproliferative effect of IFN-gamma in immune regulation. III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-gamma. J. Immunol. 143: 15-22
    • (1989) J. Immunol. , vol.143 , pp. 15-22
    • Gajewski, T.F.1    Joyce, J.2    Fitch, F.W.3
  • 17
    • 0025082313 scopus 로고
    • Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells
    • 17. Le Gros G., Ben S.S., Seder R., Finkelman F.D., Paul W.E. 1990. Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. J. Exp. Med. 172: 921-929
    • (1990) J. Exp. Med. , vol.172 , pp. 921-929
    • Le Gros, G.1    Ben, S.S.2    Seder, R.3    Finkelman, F.D.4    Paul, W.E.5
  • 18
    • 0025222698 scopus 로고
    • IL-4 directs the development of Th2-like helper effectors
    • 18. Swain S.L., Weinberg A.D., English M., Huston G. 1990. IL-4 directs the development of Th2-like helper effectors. J. Immunol. 145: 3796-3806
    • (1990) J. Immunol. , vol.145 , pp. 3796-3806
    • Swain, S.L.1    Weinberg, A.D.2    English, M.3    Huston, G.4
  • 19
    • 0027199519 scopus 로고
    • Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo
    • 19. Powrie F., Menon S., Coffman R.L. 1993. Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo. Eur. J. Immunol. 23: 2223-2229
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2223-2229
    • Powrie, F.1    Menon, S.2    Coffman, R.L.3
  • 20
    • 0027529932 scopus 로고
    • Surface expression of α 4 integrin by CD4 T cells is required for their entry into brain parenchyma
    • 20. Baron J.L., Madri J.A., Ruddle N.H., Hashim G., Janeway C.J. 1993. Surface expression of α 4 integrin by CD4 T cells is required for their entry into brain parenchyma. J. Exp. Med. 177: 57-68
    • (1993) J. Exp. Med. , vol.177 , pp. 57-68
    • Baron, J.L.1    Madri, J.A.2    Ruddle, N.H.3    Hashim, G.4    Janeway, C.J.5
  • 21
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • 21. Chen Y., Kuchroo V.K., Inobe J., Hafler D.A., Weiner H.L. 1994. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265: 1237-1240
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 22
    • 0028949152 scopus 로고
    • B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
    • 22. Kuchroo V.K., Prabhu Das M., Brown J.A., Ranger A.M., Zamvil S.S., Sobel R.A., Weiner H.L., Nabavi N., Glimcher L.H. 1995. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 80: 707-718
    • (1995) Cell , vol.80 , pp. 707-718
    • Kuchroo, V.K.1    Prabhu Das, M.2    Brown, J.A.3    Ranger, A.M.4    Zamvil, S.S.5    Sobel, R.A.6    Weiner, H.L.7    Nabavi, N.8    Glimcher, L.H.9
  • 23
    • 0027427223 scopus 로고
    • Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis
    • 23. Kuchroo V.K., Martin C.A., Greer J.M., Ju S.T., Sobel R.A., Dorf M.E. 1993. Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis. J. Immunol. 151: 4371-4382
    • (1993) J. Immunol. , vol.151 , pp. 4371-4382
    • Kuchroo, V.K.1    Martin, C.A.2    Greer, J.M.3    Ju, S.T.4    Sobel, R.A.5    Dorf, M.E.6
  • 24
    • 0015264390 scopus 로고
    • Large scale preparation of myelin basic protein from central nervous tissue of several mammalian species
    • 24. Deibler G.E., Martenson R.E., Kies M.W. 1972. Large scale preparation of myelin basic protein from central nervous tissue of several mammalian species. Prep. Biochem. 2: 139-165
    • (1972) Prep. Biochem. , vol.2 , pp. 139-165
    • Deibler, G.E.1    Martenson, R.E.2    Kies, M.W.3
  • 25
    • 0022974996 scopus 로고
    • T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis
    • 25. Zamvil S.S., Mitchell D.J., Moore A.C., Kitamura K., Steinman L., Rothbard J.B. 1986. T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis. Nature 324: 258-260
    • (1986) Nature , vol.324 , pp. 258-260
    • Zamvil, S.S.1    Mitchell, D.J.2    Moore, A.C.3    Kitamura, K.4    Steinman, L.5    Rothbard, J.B.6
  • 26
    • 0025275036 scopus 로고
    • Detection of individual mouse splenic T cells producing IFN-gamma and IL-5 using the enzyme-linked immunospot (ELISPOT) assay
    • 26. Taguchi T., McGhee J.R., Coffman R.L., Beagley K.W., Eldridge J.H., Takatsu K., Kiyono H. 1990. Detection of individual mouse splenic T cells producing IFN-gamma and IL-5 using the enzyme-linked immunospot (ELISPOT) assay. J. Immunol. Meth. 128: 65-73
    • (1990) J. Immunol. Meth. , vol.128 , pp. 65-73
    • Taguchi, T.1    McGhee, J.R.2    Coffman, R.L.3    Beagley, K.W.4    Eldridge, J.H.5    Takatsu, K.6    Kiyono, H.7
  • 27
    • 0024327899 scopus 로고
    • Clonal expansion versus functional inactivation: A costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy
    • 27. Mueller D.L., Jenkins M.K., Schwartz R.H. 1989. Clonal expansion versus functional inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy. Ann. Rev. Immunol. 7: 445-480
    • (1989) Ann. Rev. Immunol. , vol.7 , pp. 445-480
    • Mueller, D.L.1    Jenkins, M.K.2    Schwartz, R.H.3
  • 29
    • 0029121077 scopus 로고
    • Down-regulation of CD8 on mature antigen-reactive T cells as a mechanism of peripheral tolerance
    • 29. Zhang L., Fung-Leung W., Miller R.G. 1995. Down-regulation of CD8 on mature antigen-reactive T cells as a mechanism of peripheral tolerance. J. Immunol. 155: 3464-3471
    • (1995) J. Immunol. , vol.155 , pp. 3464-3471
    • Zhang, L.1    Fung-Leung, W.2    Miller, R.G.3
  • 31
    • 0026027479 scopus 로고
    • Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway
    • 31. Dallman M.J., Shiho O., Page T.H., Wood K.J., Morris P.J. 1991. Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway. J. Exp. Med. 173: 79-87
    • (1991) J. Exp. Med. , vol.173 , pp. 79-87
    • Dallman, M.J.1    Shiho, O.2    Page, T.H.3    Wood, K.J.4    Morris, P.J.5
  • 32
    • 0023143676 scopus 로고
    • Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo
    • 32. Jenkins M.K., Schwartz R.H. 1987. Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J. Exp. Med. 165: 302-319
    • (1987) J. Exp. Med. , vol.165 , pp. 302-319
    • Jenkins, M.K.1    Schwartz, R.H.2
  • 33
    • 0025791940 scopus 로고
    • Clonal anergy is induced in vitro by T cell receptor occupancy in the absence of proliferation
    • 33. DeSilva D.R., Urdahl K.B., Jenkins M.C. 1991. Clonal anergy is induced in vitro by T cell receptor occupancy in the absence of proliferation. J. Immunol. 147: 3261-3267
    • (1991) J. Immunol. , vol.147 , pp. 3261-3267
    • DeSilva, D.R.1    Urdahl, K.B.2    Jenkins, M.C.3
  • 34
    • 0026687519 scopus 로고
    • Reversal of in vitro T cell clonal anergy by IL-2 stimulation
    • 34. Beverly B., Kang S.M., Lenardo M.J., Schwartz R.H. 1992. Reversal of in vitro T cell clonal anergy by IL-2 stimulation. Inter. Immunol. 4: 661-671
    • (1992) Inter. Immunol. , vol.4 , pp. 661-671
    • Beverly, B.1    Kang, S.M.2    Lenardo, M.J.3    Schwartz, R.H.4
  • 35
    • 0025174370 scopus 로고
    • Inhibition of murine relapsing experimental autoimmune encephalomyelitis by immune tolerance to proteolipid protein and its encephalitogenic peptides
    • 35. Kennedy M.K., Tan L.J., Dal Canto M.C., Tuohy Z.J., Lu Z.J., Trotter J.L., Miller S.D. 1990. Inhibition of murine relapsing experimental autoimmune encephalomyelitis by immune tolerance to proteolipid protein and its encephalitogenic peptides. J. Immunol. 144: 909-915
    • (1990) J. Immunol. , vol.144 , pp. 909-915
    • Kennedy, M.K.1    Tan, L.J.2    Dal Canto, M.C.3    Tuohy, Z.J.4    Lu, Z.J.5    Trotter, J.L.6    Miller, S.D.7
  • 36
    • 0027056539 scopus 로고
    • Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy
    • 36. Gaur A., Brook W., Liu A., Rothbard J., Fathman C.G. 1992. Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy. Science 258: 1491-1494
    • (1992) Science , vol.258 , pp. 1491-1494
    • Gaur, A.1    Brook, W.2    Liu, A.3    Rothbard, J.4    Fathman, C.G.5
  • 37
    • 0026027162 scopus 로고
    • Lymphocytes from SJL/J mice immunized with spinal cord respond selectively to a peptide of proteolipid protein and transfer relapsing demyelinating experimental autoimmune encephalomyelitis
    • 37. Whitham R.H., Bourdette D.N., Hashim G.A., Herndon R.M., Ilg R.C., Vandenbark A.A., Offner H. 1991. Lymphocytes from SJL/J mice immunized with spinal cord respond selectively to a peptide of proteolipid protein and transfer relapsing demyelinating experimental autoimmune encephalomyelitis. J. Immunol. 146: 101-107
    • (1991) J. Immunol. , vol.146 , pp. 101-107
    • Whitham, R.H.1    Bourdette, D.N.2    Hashim, G.A.3    Herndon, R.M.4    Ilg, R.C.5    Vandenbark, A.A.6    Offner, H.7
  • 39
    • 0025176996 scopus 로고
    • Anti-CD3 antibody induces unresponsiveness to IL2 in Th1 clones but not in Th2 clones
    • 39. Williams M.E., Lichtman A.H., Abbas A.K. 1990. Anti-CD3 antibody induces unresponsiveness to IL2 in Th1 clones but not in Th2 clones. J. Immunol. 144: 1208-1214
    • (1990) J. Immunol. , vol.144 , pp. 1208-1214
    • Williams, M.E.1    Lichtman, A.H.2    Abbas, A.K.3
  • 41
    • 0028364520 scopus 로고
    • Anergy in vivo: Down-regulation of antigen-specific CD4+ Th1 but not Th2 cytokine responses
    • 41. Karpus W.J., Peterson J.D., Miller S.D. 1994. Anergy in vivo: down-regulation of antigen-specific CD4+ Th1 but not Th2 cytokine responses. Inter. Immunol. 6: 721-730
    • (1994) Inter. Immunol. , vol.6 , pp. 721-730
    • Karpus, W.J.1    Peterson, J.D.2    Miller, S.D.3
  • 42
    • 0027448605 scopus 로고
    • The major histocompatibility complex influences myelin basic protein 63-88-induced T cell cytokine profile and experimental autoimmune encephalomyelitis
    • 42. Mustafa M., Vingsbo C., Olsson T., Ljungdahl A., Hojeberg B., Holmdahl R. 1993. The major histocompatibility complex influences myelin basic protein 63-88-induced T cell cytokine profile and experimental autoimmune encephalomyelitis. Eur. J. Immunol. 23: 3089-3095
    • (1993) Eur. J. Immunol. , vol.23 , pp. 3089-3095
    • Mustafa, M.1    Vingsbo, C.2    Olsson, T.3    Ljungdahl, A.4    Hojeberg, B.5    Holmdahl, R.6
  • 43
    • 0017819983 scopus 로고
    • Corticosteroid-induced lymphopenia, immunosuppression, and body defense
    • 43. Craddock C.G. 1978. Corticosteroid-induced lymphopenia, immunosuppression, and body defense. Ann. Int. Med. 88: 564-566
    • (1978) Ann. Int. Med. , vol.88 , pp. 564-566
    • Craddock, C.G.1
  • 44
    • 0029011165 scopus 로고
    • Effects of stress on immune cell distribution. Dynamics and hormonal mechanisms
    • 44. Dhabhar F.S., Miller A.H., McEwen B.S., Spencer R.L. 1995. Effects of stress on immune cell distribution. Dynamics and hormonal mechanisms. J. Immunol. 154: 5511-5527
    • (1995) J. Immunol. , vol.154 , pp. 5511-5527
    • Dhabhar, F.S.1    Miller, A.H.2    McEwen, B.S.3    Spencer, R.L.4
  • 45
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-kB activity through induction of IkB synthesis
    • 45. Auphan N., DiDonato J.A., Rosette C., Helmberg A., Karin M. 1995. Immunosuppression by glucocorticoids: inhibition of NF-kB activity through induction of IkB synthesis. Science 270: 286-289
    • (1995) Science , vol.270 , pp. 286-289
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 46
    • 0024534407 scopus 로고
    • Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids
    • 46. MacPhee I.A., Antoni F.A., Mason D.W. 1989. Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids. J. Exp. Med. 169: 431-445
    • (1989) J. Exp. Med. , vol.169 , pp. 431-445
    • MacPhee, I.A.1    Antoni, F.A.2    Mason, D.W.3
  • 47
    • 0024802919 scopus 로고
    • Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4
    • 47. Daynes R.A., Araneo B.A. 1989. Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4. Eur. J. Immunol. 19: 2319-2325
    • (1989) Eur. J. Immunol. , vol.19 , pp. 2319-2325
    • Daynes, R.A.1    Araneo, B.A.2
  • 48
    • 0028138531 scopus 로고
    • Alterations in interleukin-4 and antibody production following pheromone exposure: Role of glucocorticoids
    • 48. Moynihan J.A., Karp J.D., Cohen N., Cocke R. 1994. Alterations in interleukin-4 and antibody production following pheromone exposure: Role of glucocorticoids. J. Neuroimmunol. 54: 51-58
    • (1994) J. Neuroimmunol. , vol.54 , pp. 51-58
    • Moynihan, J.A.1    Karp, J.D.2    Cohen, N.3    Cocke, R.4
  • 50
    • 0026661264 scopus 로고
    • Apoptosis of αβ T lymphocytes in the nervous system in experimental autoimmune encephalomyelitis: Its possible implications for recovery and acquired tolerance
    • 50. Pender M.P., McCombe P.A., Yoong G., Nguyen K.B. 1992. Apoptosis of αβ T lymphocytes in the nervous system in experimental autoimmune encephalomyelitis: its possible implications for recovery and acquired tolerance. J. Autoimm. 5: 401-410
    • (1992) J. Autoimm. , vol.5 , pp. 401-410
    • Pender, M.P.1    McCombe, P.A.2    Yoong, G.3    Nguyen, K.B.4
  • 51
    • 0027773017 scopus 로고
    • Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis. Evidence for programmed cell death as a mechanism to control inflammation in the brain
    • 51. Schmeid M., Brietschopf H., Gold R., Zischler H., Rothe G., Wekerle H., Lassmann H. 1993. Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis. Evidence for programmed cell death as a mechanism to control inflammation in the brain. Amer. J. Pathol. 143: 446-452
    • (1993) Amer. J. Pathol. , vol.143 , pp. 446-452
    • Schmeid, M.1    Brietschopf, H.2    Gold, R.3    Zischler, H.4    Rothe, G.5    Wekerle, H.6    Lassmann, H.7
  • 54
    • 0026621411 scopus 로고
    • Expression of CD45RC and Ia antigen in the spinal cord in acute experimental allergic encephalomyelitis: An immunocytochemical and flow cytometric study
    • 54. McCombe P.A., Fordyce B.W., de Jersey J., Yoong G., Pender M.P. 1992. Expression of CD45RC and Ia antigen in the spinal cord in acute experimental allergic encephalomyelitis: an immunocytochemical and flow cytometric study. J. Neurol. Sci. 113: 177-186
    • (1992) J. Neurol. Sci. , vol.113 , pp. 177-186
    • McCombe, P.A.1    Fordyce, B.W.2    De Jersey, J.3    Yoong, G.4    Pender, M.P.5
  • 55
    • 0026630032 scopus 로고
    • + T cells that induce experimental allergic encephalomyelitis
    • + T cells that induce experimental allergic encephalomyelitis. J. Neuroimmunol. 40: 57-69
    • (1992) J. Neuroimmunol. , vol.40 , pp. 57-69
    • Zeine, R.1    Owens, T.2
  • 56
    • 0028299065 scopus 로고
    • The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis
    • 56. Salmon M., Pilling D., Borthwick N.J., Viner N., Janossy G., Bacon P.A., Akbar A.N. 1994. The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis. Eur. J. Immunol. 24: 892-899
    • (1994) Eur. J. Immunol. , vol.24 , pp. 892-899
    • Salmon, M.1    Pilling, D.2    Borthwick, N.J.3    Viner, N.4    Janossy, G.5    Bacon, P.A.6    Akbar, A.N.7
  • 57
    • 0027281563 scopus 로고
    • The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory
    • 57. Akbar A.N., Borthwick N., Salmon M., Gombert W., Bofill M., Shamsadeen N., Pilling D., Pett S., Grundy J.E., Janossy G. 1993. The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory. J. Exp. Med. 178: 427-438
    • (1993) J. Exp. Med. , vol.178 , pp. 427-438
    • Akbar, A.N.1    Borthwick, N.2    Salmon, M.3    Gombert, W.4    Bofill, M.5    Shamsadeen, N.6    Pilling, D.7    Pett, S.8    Grundy, J.E.9    Janossy, G.10
  • 59
    • 0026017971 scopus 로고
    • Interleukin-2 programs mouse αβ T lymphocytes for apoptosis
    • 59. Lenardo M.J. 1991. Interleukin-2 programs mouse αβ T lymphocytes for apoptosis. Nature 353: 858-861.
    • (1991) Nature , vol.353 , pp. 858-861
    • Lenardo, M.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.