메뉴 건너뛰기




Volumn 250, Issue 5, 2003, Pages 607-611

Investigation of a genetic variation of a variable number tandem repeat polymorphism of interleukin-6 gene in patients with multiple sclerosis

Author keywords

Genetic polymorphisms; Interleukin 6 gene; Multiple sclerosis

Indexed keywords

INTERLEUKIN 6;

EID: 0037565162     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00415-003-1051-y     Document Type: Article
Times cited : (13)

References (27)
  • 1
  • 2
    • 0031795197 scopus 로고    scopus 로고
    • Genetics of multiple sclerosis
    • Ebers G, Dyment D (1998) Genetics of multiple sclerosis. Semin Neurol 18:295-299
    • (1998) Semin Neurol , vol.18 , pp. 295-299
    • Ebers, G.1    Dyment, D.2
  • 4
    • 0024504359 scopus 로고
    • The natural history of multiple sclerosis: A geographically based study. I. Clinical course and disability
    • Weinshenker BG, Bass B, Rice GP, Noseworthy J, Carriere W, Baskerville J, Ebers J (1989) The natural history of multiple sclerosis: a geographically based study. I. Clinical course and disability. Brain 112:133-146
    • (1989) Brain , vol.112 , pp. 133-146
    • Weinshenker, B.G.1    Bass, B.2    Rice, G.P.3    Noseworthy, J.4    Carriere, W.5    Baskerville, J.6    Ebers, J.7
  • 6
    • 0030056764 scopus 로고    scopus 로고
    • Distinct patterns of multiple sclerosis pathology indicates heterogeneity in pathogenesis
    • Lucchinetti CL, Brück WB, Rodriguez M, Lassmann H (1996) Distinct patterns of multiple sclerosis pathology indicates heterogeneity in pathogenesis. Brain Pathol 6:259-274
    • (1996) Brain Pathol , vol.6 , pp. 259-274
    • Lucchinetti, C.L.1    Brück, W.B.2    Rodriguez, M.3    Lassmann, H.4
  • 10
    • 0032914896 scopus 로고    scopus 로고
    • A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease
    • Papassotiropoulos A, Bagli M, Jessen F, Bayer AT, Maier W, Rao ML, Heun R (1999) A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease. Ann Neurol 45:666-668
    • (1999) Ann Neurol , vol.45 , pp. 666-668
    • Papassotiropoulos, A.1    Bagli, M.2    Jessen, F.3    Bayer, A.T.4    Maier, W.5    Rao, M.L.6    Heun, R.7
  • 14
    • 0031852288 scopus 로고    scopus 로고
    • IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
    • Eugster HP, Frei K, Kopf M, Lassmann H, Fontana A (1998) IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. Eur J Immunol 28:2178-2187
    • (1998) Eur J Immunol , vol.28 , pp. 2178-2187
    • Eugster, H.P.1    Frei, K.2    Kopf, M.3    Lassmann, H.4    Fontana, A.5
  • 15
    • 0029411144 scopus 로고
    • Administration of neutralizing antibodies to interleukin-6 (IL-6) reduces experimental autoimmune encephalomyelitis and is associated with elevated levels of IL-6 bioactivity in central nervous system and circulation
    • Gijbels K, Brocke S, Abrams JS, Steinman L (1995) Administration of neutralizing antibodies to interleukin-6 (IL-6) reduces experimental autoimmune encephalomyelitis and is associated with elevated levels of IL-6 bioactivity in central nervous system and circulation. Mol Med 1:795-805
    • (1995) Mol Med , vol.1 , pp. 795-805
    • Gijbels, K.1    Brocke, S.2    Abrams, J.S.3    Steinman, L.4
  • 16
    • 0034711596 scopus 로고    scopus 로고
    • No association of serum levels of interleukin-6 and its soluble receptor components with a genetic variation in the 3′flanking region of the interleukin-6 gene in patients with multiple sclerosis
    • Schmidt S, Papassotiropoulos A, Bagli M, Harzheim M, Heun R, Klockgether T (2000) No association of serum levels of interleukin-6 and its soluble receptor components with a genetic variation in the 3′flanking region of the interleukin-6 gene in patients with multiple sclerosis. Neurosci Lett 294:139-142
    • (2000) Neurosci Lett , vol.294 , pp. 139-142
    • Schmidt, S.1    Papassotiropoulos, A.2    Bagli, M.3    Harzheim, M.4    Heun, R.5    Klockgether, T.6
  • 18
    • 0037154143 scopus 로고    scopus 로고
    • Multiple sclerosis distribution in northern Sardinia. Spatial cluster analysis of prevalence
    • Pugliati M, Solinas G, Sotgiu S, Castiglia P, Rosati G (2002) Multiple sclerosis distribution in northern Sardinia. Spatial cluster analysis of prevalence. Neurology 58:277-282
    • (2002) Neurology , vol.58 , pp. 277-282
    • Pugliati, M.1    Solinas, G.2    Sotgiu, S.3    Castiglia, P.4    Rosati, G.5
  • 19
    • 0029913882 scopus 로고    scopus 로고
    • Defining the clinical course of multiple sclerosis: Results of an international survey
    • National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis
    • Lublin F, Reingold S (1996) Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Neurology 46:907-911
    • (1996) Neurology , vol.46 , pp. 907-911
    • Lublin, F.1    Reingold, S.2
  • 20
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
    • Kurtzke IF (1983) Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology 33:1444-1452
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, I.F.1
  • 21
    • 0035130536 scopus 로고    scopus 로고
    • A family study of Alzheimer disease and early- and late-onset depression in elderly patients
    • Heun R, Papassotiropoulos A, Jessen F, Maier W, Breitner JC (2001) A family study of Alzheimer disease and early- and late-onset depression in elderly patients. Arch Gen Psychiatry 58:190-196
    • (2001) Arch Gen Psychiatry , vol.58 , pp. 190-196
    • Heun, R.1    Papassotiropoulos, A.2    Jessen, F.3    Maier, W.4    Breitner, J.C.5
  • 22
    • 0024423898 scopus 로고
    • Rapid detection and sequencing of alleles in the 3′flanking region of the interleukin-6 gene
    • Bowcock AM, Ray A, Ehrlich H, Sehgal PB (1989) Rapid detection and sequencing of alleles in the 3′flanking region of the interleukin-6 gene. Nucleic Acids Res 17:6855-6864
    • (1989) Nucleic Acids Res , vol.17 , pp. 6855-6864
    • Bowcock, A.M.1    Ray, A.2    Ehrlich, H.3    Sehgal, P.B.4
  • 23
    • 0030857328 scopus 로고    scopus 로고
    • Polymorphisms of the interleukin-6 gene are associated with bone mineral density
    • Murray RE, McGuigan F, Grant SF, Reid DM, Ralston SH (1997) Polymorphisms of the interleukin-6 gene are associated with bone mineral density. Bone 21:89-92
    • (1997) Bone , vol.21 , pp. 89-92
    • Murray, R.E.1    McGuigan, F.2    Grant, S.F.3    Reid, D.M.4    Ralston, S.H.5
  • 24
    • 0035691010 scopus 로고    scopus 로고
    • Genetics of interleukin 6: Implications for Alzheimer's disease
    • Papassotiropoulos A, Hock C, Nitsch RM (2001) Genetics of interleukin 6: implications for Alzheimer's disease. Neurobiol Aging 22:863-871
    • (2001) Neurobiol Aging , vol.22 , pp. 863-871
    • Papassotiropoulos, A.1    Hock, C.2    Nitsch, R.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.