-
3
-
-
0026605647
-
-
(c) Périgaud, C.; Gosselin, G.; Imbach, J.-L. Nucleosides & Nucleotides 1992, 11, 903-945.
-
(1992)
Nucleosides & Nucleotides
, vol.11
, pp. 903-945
-
-
Périgaud, C.1
Gosselin, G.2
Imbach, J.-L.3
-
4
-
-
0001720586
-
-
Ed. De Clercq, E.
-
(a) Herdewijn, P.; Balzarini, J.; De Clercq, E. in: Advances in Antiviral Drug Design. (Ed. De Clercq, E.), 1993, Vol. 1, 233-318.
-
(1993)
Advances in Antiviral Drug Design
, vol.1
, pp. 233-318
-
-
Herdewijn, P.1
Balzarini, J.2
De Clercq, E.3
-
5
-
-
0023188122
-
-
(b) Herdewijn, P.; Balzarini, J.; De Clercq, E.; Pauwels, R.; Baba, M.; Broder, S.; Vanderhaeghe, H. J. Med. Chem. 1987, 30, 1270-1278.
-
(1987)
J. Med. Chem.
, vol.30
, pp. 1270-1278
-
-
Herdewijn, P.1
Balzarini, J.2
De Clercq, E.3
Pauwels, R.4
Baba, M.5
Broder, S.6
Vanderhaeghe, H.7
-
6
-
-
0001587762
-
-
(c) Mitsuya, H.; Broder, S. Proc. Natl. Acad. Sci., USA 1986, 83, 1911-1915.
-
(1986)
Proc. Natl. Acad. Sci., USA
, vol.83
, pp. 1911-1915
-
-
Mitsuya, H.1
Broder, S.2
-
7
-
-
0022996630
-
-
Furman, P.A.; Fyfe, J.A.; St. Clair, M.H.; Weinhold, K.; Rideout, J.L.; Freeman, G.A.; Lehrmann, S.N.; Bolognesi, D.P.; Broder, S. Proc. Natl. Acad. Sci., USA 1986, 83, 8333-8337.
-
(1986)
Proc. Natl. Acad. Sci., USA
, vol.83
, pp. 8333-8337
-
-
Furman, P.A.1
Fyfe, J.A.2
St. Clair, M.H.3
Weinhold, K.4
Rideout, J.L.5
Freeman, G.A.6
Lehrmann, S.N.7
Bolognesi, D.P.8
Broder, S.9
-
9
-
-
0023732121
-
-
(b) Hao, Z.; Cooney, D.A.; Hartman, N.R.; Perno, C.-F.; Fridland, A.; DeVico, A.L.; Sarngadharan, M.G.; Broder, S.; Johns, D.G. Mol. Pharmacol 1988, 54, 431-435.
-
(1988)
Mol. Pharmacol
, vol.54
, pp. 431-435
-
-
Hao, Z.1
Cooney, D.A.2
Hartman, N.R.3
Perno, C.-F.4
Fridland, A.5
DeVico, A.L.6
Sarngadharan, M.G.7
Broder, S.8
Johns, D.G.9
-
10
-
-
0029086438
-
-
(a) Riddler, S.A.; Andersen, R.E.; Mellors, J.W. Antiviral Res. 1995, 27, 189-203.
-
(1995)
Antiviral Res.
, vol.27
, pp. 189-203
-
-
Riddler, S.A.1
Andersen, R.E.2
Mellors, J.W.3
-
13
-
-
0023124801
-
-
(d) Baba, M.; Pauwels, R.; Herdewijn, P.; De Clercq, E.; Desmyter, J.; Vandeputte, M. Biochem. Biophys. Res. Commun. 1987, 142, 128-134.
-
(1987)
Biochem. Biophys. Res. Commun.
, vol.142
, pp. 128-134
-
-
Baba, M.1
Pauwels, R.2
Herdewijn, P.3
De Clercq, E.4
Desmyter, J.5
Vandeputte, M.6
-
14
-
-
0024564518
-
-
(e) Mansuri, M.M.; Starrett Jr, J.E.; Ghazzouli, I.; Hitchcock, M.J.M.; Sterzycki, R.Z.; Brankovan, V.; Lin, T.-S.; August, E.M.; Prusoff, W.H.; Sommadossi, J.-P.; Martin, J.C. J. Med. Chem. 1989, 32, 461-466.
-
(1989)
J. Med. Chem.
, vol.32
, pp. 461-466
-
-
Mansuri, M.M.1
Starrett Jr., J.E.2
Ghazzouli, I.3
Hitchcock, M.J.M.4
Sterzycki, R.Z.5
Brankovan, V.6
Lin, T.-S.7
August, E.M.8
Prusoff, W.H.9
Sommadossi, J.-P.10
Martin, J.C.11
-
15
-
-
0023196616
-
-
(f) Lin, T.-S.; Schinazi, R.F.; Prusoff, W.H. Biochem. Pharmacol. 1987, 36, 2713-2718.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 2713-2718
-
-
Lin, T.-S.1
Schinazi, R.F.2
Prusoff, W.H.3
-
16
-
-
0025344520
-
-
(g) Zhu, Z.; Ho, H.-T.; Hitchcock, M.J.M.; Sommadossi, J.-P. Biochem. Pharmacol. 1990, 39, R15-R19.
-
(1990)
Biochem. Pharmacol.
, vol.39
-
-
Zhu, Z.1
Ho, H.-T.2
Hitchcock, M.J.M.3
Sommadossi, J.-P.4
-
17
-
-
0024592935
-
-
(a) Balzarini, J.; Herdewijn, P.; De Clercq, E. J. Biol. Chem. 1989, 264, 6127-6133.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 6127-6133
-
-
Balzarini, J.1
Herdewijn, P.2
De Clercq, E.3
-
18
-
-
0023265911
-
-
(b) Balzarini, J.; Kang, G.-J.; Dalal, M.; Herdewijn, P.; De Clercq, E.; Broder, S.; Johns, D.G. Mol. Pharmacol. 1987, 32, 162-167.
-
(1987)
Mol. Pharmacol.
, vol.32
, pp. 162-167
-
-
Balzarini, J.1
Kang, G.-J.2
Dalal, M.3
Herdewijn, P.4
De Clercq, E.5
Broder, S.6
Johns, D.G.7
-
20
-
-
0025122369
-
-
Hao, Z.; Cooney, D.A.; Farquhar, D.; Perno, C.-F.; Zhang, K.; Masood, R.; Wilson, Y.; Hartman, N.R.; Balzarini, J.; Johns, D.G. Mol. Pharmacol. 1990, 37, 157-163.
-
(1990)
Mol. Pharmacol.
, vol.37
, pp. 157-163
-
-
Hao, Z.1
Cooney, D.A.2
Farquhar, D.3
Perno, C.-F.4
Zhang, K.5
Masood, R.6
Wilson, Y.7
Hartman, N.R.8
Balzarini, J.9
Johns, D.G.10
-
21
-
-
0023228134
-
-
(a) Cooney, D.A.; Ahluwalia, G.; Mitsuya, H.; Fridland, A.; Johnson, M.A.; Hao, Z.; Dalal, M.; Balzarini, J.; Broder, S.; Johns, D.G. Biochem. Pharmacol. 1987, 36, 1765-1768.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 1765-1768
-
-
Cooney, D.A.1
Ahluwalia, G.2
Mitsuya, H.3
Fridland, A.4
Johnson, M.A.5
Hao, Z.6
Dalal, M.7
Balzarini, J.8
Broder, S.9
Johns, D.G.10
-
22
-
-
0014127726
-
-
(b) Bloch, A.; Robins, M.J.; McCarthy, J.R., Jr. J. Med. Chem. 1967, 10, 908-912.
-
(1967)
J. Med. Chem.
, vol.10
, pp. 908-912
-
-
Bloch, A.1
Robins, M.J.2
McCarthy Jr., J.R.3
-
23
-
-
0023808097
-
-
Johnson, M.A.; Ahluwalia, G.; Connelly, M.C.; Cooney, D.A.; Broder, S.; Johns, D.G. J. Biol. Chem. 1988, 263, 15354-15357.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 15354-15357
-
-
Johnson, M.A.1
Ahluwalia, G.2
Connelly, M.C.3
Cooney, D.A.4
Broder, S.5
Johns, D.G.6
-
24
-
-
0001707601
-
-
Mitsuya, H.; Weinhold, K.J.; Furman, P.A.; St. Clair, M.H.; Nusinoff-Lehrman, S.; Gallo, R.C.; Bolognesi, D.; Barry, D.W.; Broder, S. Proc. Natl. Acad. Sci., USA 1985, 82, 7096-7100.
-
(1985)
Proc. Natl. Acad. Sci., USA
, vol.82
, pp. 7096-7100
-
-
Mitsuya, H.1
Weinhold, K.J.2
Furman, P.A.3
St. Clair, M.H.4
Nusinoff-Lehrman, S.5
Gallo, R.C.6
Bolognesi, D.7
Barry, D.W.8
Broder, S.9
-
25
-
-
1842330863
-
-
(a) Cinatl Jr, J.; Gröschel, B.; Zehner, R.; Cinatl, J.; Périgaud, C.; Gosselin, G.; Imbach, J.-L.; Doerr, H.W. Antiviral Chem. & Chemother. 1997, 8, 343-352.
-
(1997)
Antiviral Chem. & Chemother.
, vol.8
, pp. 343-352
-
-
Cinatl Jr., J.1
Gröschel, B.2
Zehner, R.3
Cinatl, J.4
Périgaud, C.5
Gosselin, G.6
Imbach, J.-L.7
Doerr, H.W.8
-
26
-
-
0028149110
-
-
(b) Dianzani, F.; Antonelli, G.; Turriziani, O.; Riva, E.; Swimeoni, E.; Signoretti, C.; Strosselli, S.; Cianfriglia, M. AIDS Res. Human Retroviruses 1994, 10, 1471-1478.
-
(1994)
AIDS Res. Human Retroviruses
, vol.10
, pp. 1471-1478
-
-
Dianzani, F.1
Antonelli, G.2
Turriziani, O.3
Riva, E.4
Swimeoni, E.5
Signoretti, C.6
Strosselli, S.7
Cianfriglia, M.8
-
27
-
-
0029015084
-
-
A more extensive overview of older nucleoside and nucleotide prodrugs summarizing also part of the tripartate prodrug concepts can be found in: Jones, R.J.; Bischofberger, N. Antiviral Res. 1995, 27, 1-17 and cited literature.
-
(1995)
Antiviral Res.
, vol.27
, pp. 1-17
-
-
Jones, R.J.1
Bischofberger, N.2
-
28
-
-
77956802548
-
-
Ed. De Clercq, E.
-
(b) Périgaud, C.; Giradet, J.-L.; Gosselin, G.; Imbach, J.-L. in: Advances in Antiviral Drug Design. (Ed. De Clercq, E.), 1996, Vol. 2, 147-172.
-
(1996)
Advances in Antiviral Drug Design
, vol.2
, pp. 147-172
-
-
Périgaud, C.1
Giradet, J.-L.2
Gosselin, G.3
Imbach, J.-L.4
-
32
-
-
0019453510
-
-
Carl, P.L.; Chakravarty, P.K.; Katzenellenbogen, J.A. J. Med. Chem. 1981, 24, 479-480.
-
(1981)
J. Med. Chem.
, vol.24
, pp. 479-480
-
-
Carl, P.L.1
Chakravarty, P.K.2
Katzenellenbogen, J.A.3
-
35
-
-
0015621911
-
-
(b) Ashini, Y.; Snyder, S.; Wilson, I. J. Med. Chem. 1973, 16, 446.
-
(1973)
J. Med. Chem.
, vol.16
, pp. 446
-
-
Ashini, Y.1
Snyder, S.2
Wilson, I.3
-
36
-
-
2642599622
-
-
It is well known in literature that phosphodiesters are extremely stable against chemical hydrolysis at physiological pH values: Bunton, C.A.; Mhala, M.M.; Oldham, K.G.; Vernon, C.A. J. Chem. Soc. 1960, 3293-3301.
-
(1960)
J. Chem. Soc.
, pp. 3293-3301
-
-
Bunton, C.A.1
Mhala, M.M.2
Oldham, K.G.3
Vernon, C.A.4
-
37
-
-
37049128024
-
-
Even the "reactive" diphenylphosphate showed a half live of 180 years(!) at pH 7.0 and 100°C: Kirby, A.J.; Younas, M. J. Chem. Soc. (B) 1970, 510-513.
-
(1970)
J. Chem. Soc. (B)
, pp. 510-513
-
-
Kirby, A.J.1
Younas, M.2
-
39
-
-
0001588112
-
-
(b) Buchwald, S.L. Pliura, D.H.; Knowles, J.R. J. Am. Chem. Soc. 1984, 106, 4916-4922.
-
(1984)
J. Am. Chem. Soc.
, vol.106
, pp. 4916-4922
-
-
Buchwald, S.L.1
Pliura, D.H.2
Knowles, J.R.3
-
40
-
-
0028273851
-
-
Srinivas, R.V.; Robbins, B.L.; Connelly, M.C.; Gong, Y.-F.; Bischofberger, N.; Fridland, A. Int. Antiviral News 1994, 2, 53-55.
-
(1994)
Int. Antiviral News
, vol.2
, pp. 53-55
-
-
Srinivas, R.V.1
Robbins, B.L.2
Connelly, M.C.3
Gong, Y.-F.4
Bischofberger, N.5
Fridland, A.6
-
41
-
-
0020676398
-
-
Farquhar, D.; Srivastava, D.N.; Kattesch, N.J.; Saunders, P.P. J. Pharm. Sci. 1983, 72, 324-325.
-
(1983)
J. Pharm. Sci.
, vol.72
, pp. 324-325
-
-
Farquhar, D.1
Srivastava, D.N.2
Kattesch, N.J.3
Saunders, P.P.4
-
42
-
-
0026524003
-
-
Sastry, J.K.; Nehete, P.N.; Khan, S.; Nowak, B.J.; Plunkett, W.; Arlinghaus, R.B.; Farquhar, D. Mol. Pharmacol. 1992, 41, 441-445.
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 441-445
-
-
Sastry, J.K.1
Nehete, P.N.2
Khan, S.3
Nowak, B.J.4
Plunkett, W.5
Arlinghaus, R.B.6
Farquhar, D.7
-
43
-
-
0028290089
-
-
Pompon, A.; Lefebvre, L; Imbach, J.-L.; Khan, S.; Farquhar, D. Antiviral Chem. Chemother. 1994, 5, 91-98.
-
(1994)
Antiviral Chem. Chemother.
, vol.5
, pp. 91-98
-
-
Pompon, A.1
Lefebvre, L.2
Imbach, J.-L.3
Khan, S.4
Farquhar, D.5
-
44
-
-
0027440278
-
-
Srinivas, R.V.; Robbins, B.L.; Connelly, M.C.; Gong, Y.-R; Bischofberger, N.; Fridland, A. Antimicrob. Agents Chemother. 1993, 37, 2247-2250.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 2247-2250
-
-
Srinivas, R.V.1
Robbins, B.L.2
Connelly, M.C.3
Gong, Y.-R.4
Bischofberger, N.5
Fridland, A.6
-
45
-
-
0027943194
-
-
(a) Farquhar, D.; Khan, S.; Srivastva, D.M.; Saunders, P.P. J. Med. Chem. 1994, 37, 3902- 3909.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 3902-3909
-
-
Farquhar, D.1
Khan, S.2
Srivastva, D.M.3
Saunders, P.P.4
-
46
-
-
0029014710
-
-
(b) Farquhar, D.; Chen, R.; Khan, S. J. Med. Chem. 1995, 38, 488-495.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 488-495
-
-
Farquhar, D.1
Chen, R.2
Khan, S.3
-
47
-
-
11244275268
-
-
Abstract OP11; September 15-19, La Jolla, USA
-
Jones, R.J.; Arimilli, M.N.; Lin, K.-Y.; Louie, M.S.; McGee, L.R.; Shaw, J.-P.; Burman, D.; Lee, M.; Kennedy, J.A.; Prisbe, E.J.; Bischofberger, N.; Lee, W.A.; Cundy, K.C. Abstract OP11; XII International Roundtable Nucleosides, Nucleotides and their biological Application, September 15-19, 1996, La Jolla, USA.
-
(1996)
XII International Roundtable Nucleosides, Nucleotides and Their Biological Application
-
-
Jones, R.J.1
Arimilli, M.N.2
Lin, K.-Y.3
Louie, M.S.4
McGee, L.R.5
Shaw, J.-P.6
Burman, D.7
Lee, M.8
Kennedy, J.A.9
Prisbe, E.J.10
Bischofberger, N.11
Lee, W.A.12
Cundy, K.C.13
-
48
-
-
0030782524
-
-
(a) Arimilli, M.N.; Kim, C.U.; Dougherty, J.; Mulato, A.; Oliyai, R.; Shaw, J. P.; Cundy, K. C.; Bischofberger, N.; Antiviral Chem. & Chemother. 1997, 8, 557-564.
-
(1997)
Antiviral Chem. & Chemother.
, vol.8
, pp. 557-564
-
-
Arimilli, M.N.1
Kim, C.U.2
Dougherty, J.3
Mulato, A.4
Oliyai, R.5
Shaw, J.P.6
Cundy, K.C.7
Bischofberger, N.8
-
49
-
-
4243992700
-
-
(b) Fridland, A.; Robbins, B.L.; Srinivas, R. V.; Arimilli, M.; Kim, C.; Bischofberger, N. Antiviral Res. 1997, 34, A49, 27.
-
(1997)
Antiviral Res.
, vol.34
-
-
Fridland, A.1
Robbins, B.L.2
Srinivas, R.V.3
Arimilli, M.4
Kim, C.5
Bischofberger, N.6
-
50
-
-
0242501239
-
-
Naesens, L.; Bischofberger, N.; Arimilli, M.; Kim, C.; De Clercq, E. Antiviral Res. 1997, 34, A50, 28;
-
(1997)
Antiviral Res.
, vol.34
-
-
Naesens, L.1
Bischofberger, N.2
Arimilli, M.3
Kim, C.4
De Clercq, E.5
-
52
-
-
0001962580
-
-
(a) Périgaud, C.; Gosselin, G.; Imbach, J.-L. Curr. Topics in Med. Chem. 1997, 2, 15-29.
-
(1997)
Curr. Topics in Med. Chem.
, vol.2
, pp. 15-29
-
-
Périgaud, C.1
Gosselin, G.2
Imbach, J.-L.3
-
53
-
-
0003149806
-
-
(b) Gosselin, G.; Giradet, J.-L.; Périgaud, C.; Benzaria, S.; Lefebvre, L; Schlienger, N.; Pompon, A.; Imbach, J.-L. Acta Biochim. Pol. 1996, 43, 195-208.
-
(1996)
Acta Biochim. Pol.
, vol.43
, pp. 195-208
-
-
Gosselin, G.1
Giradet, J.-L.2
Périgaud, C.3
Benzaria, S.4
Lefebvre, L.5
Schlienger, N.6
Pompon, A.7
Imbach, J.-L.8
-
54
-
-
0027433373
-
-
(c) Puech, F.; Gosselin, G.; Lefebvre, I.; Pompon, A.; Aubertin, A.-M.; Kirn, A.; Imbach, J.-L. Antiviral Res. 1993, 22, 155-174.
-
(1993)
Antiviral Res.
, vol.22
, pp. 155-174
-
-
Puech, F.1
Gosselin, G.2
Lefebvre, I.3
Pompon, A.4
Aubertin, A.-M.5
Kirn, A.6
Imbach, J.-L.7
-
55
-
-
0029953984
-
-
(d) Valette, G.; Pompon, A.; Girardet, J.-L.; Cappellacci, L.; Franchetti, P.; Grifantini, M.; La Colla, P.; Loi, A. G.; Périgaud, C.; Gosselin, G.; Imbach, J.-L. J. Med. Chem. 1996, 39, 1981-1990.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 1981-1990
-
-
Valette, G.1
Pompon, A.2
Girardet, J.-L.3
Cappellacci, L.4
Franchetti, P.5
Grifantini, M.6
La Colla, P.7
Loi, A.G.8
Périgaud, C.9
Gosselin, G.10
Imbach, J.-L.11
-
56
-
-
0029021039
-
-
Giradet, J.-L.; Gosselin, G.; Périgaud, C.; Balzarini, J.; De Clercq, E.; Imbach, J.-L. Nucleosides &. Nucleotides 1995, 14, 645-647.
-
(1995)
Nucleosides &. Nucleotides
, vol.14
, pp. 645-647
-
-
Giradet, J.-L.1
Gosselin, G.2
Périgaud, C.3
Balzarini, J.4
De Clercq, E.5
Imbach, J.-L.6
-
57
-
-
0029731207
-
-
(a) Benzaria, S.; Pélicano, H.; Johnson, R.; Maury, G.; Imbach, J.-L., Aubertin, A.-M.; Obert, G.; Gosselin, G. J. Med. Chem. 1996, 39, 4958-4965.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 4958-4965
-
-
Benzaria, S.1
Pélicano, H.2
Johnson, R.3
Maury, G.4
Imbach, J.-L.5
Aubertin, A.-M.6
Obert, G.7
Gosselin, G.8
-
58
-
-
0029029603
-
-
(b) Benzaria, S.; Gosselin, G.; Pélicano, H.; Maury, G.; Aubertin, A.-M.; Obert, G.; Kirn, A.; Imbach, J.-L. Nucleosides & Nucleotides 1995, 14, 563-565.
-
(1995)
Nucleosides & Nucleotides
, vol.14
, pp. 563-565
-
-
Benzaria, S.1
Gosselin, G.2
Pélicano, H.3
Maury, G.4
Aubertin, A.-M.5
Obert, G.6
Kirn, A.7
Imbach, J.-L.8
-
59
-
-
0014554921
-
-
Pugaeva, V.P.; Klochkeva, S.I.; Mashbits, F.D.; Eizengart, R.S. Gig. Tr. Prof. Zabol. 1969, 13, 47-48
-
(1969)
Gig. Tr. Prof. Zabol.
, vol.13
, pp. 47-48
-
-
Pugaeva, V.P.1
Klochkeva, S.I.2
Mashbits, F.D.3
Eizengart, R.S.4
-
60
-
-
26844508849
-
-
(Chem. Abstract 72, 212).
-
Chem. Abstract
, vol.72
, pp. 212
-
-
-
61
-
-
24644475091
-
-
Luethy, J.; Von Daeniken, A.; Friedrich, U.; Manthey, B.; Zweifel, U.; Schlatter, C.; Benn, M.H. Mitt. Geb. Lebensmittelunters. Hyg. 1981, 72, 131-133
-
(1981)
Mitt. Geb. Lebensmittelunters. Hyg.
, vol.72
, pp. 131-133
-
-
Luethy, J.1
Von Daeniken, A.2
Friedrich, U.3
Manthey, B.4
Zweifel, U.5
Schlatter, C.6
Benn, M.H.7
-
62
-
-
26844507097
-
-
(Chem. Abstracts 95, 127093).
-
Chem. Abstracts
, vol.95
, pp. 127093
-
-
-
63
-
-
0029796002
-
-
Périgaud, C.; Girardet, J.-L.; Lefebvre, I.; Xie, M.-Y.; Aubertin, A.-M.; Kirn, A.; Gosselin, G.; Imbach, J.-L.; Sommadoussi, J.-P. Antiviral Chem. & Chemother. 1996, 7, 338-345.
-
(1996)
Antiviral Chem. & Chemother.
, vol.7
, pp. 338-345
-
-
Périgaud, C.1
Girardet, J.-L.2
Lefebvre, I.3
Xie, M.-Y.4
Aubertin, A.-M.5
Kirn, A.6
Gosselin, G.7
Imbach, J.-L.8
Sommadoussi, J.-P.9
-
64
-
-
0028819889
-
-
(a) Lefebvre, I.; Périgaud, C.; Pompon, A.; Aubertin, A.-M.; Girardet, J.-L.; Kirn, A.; Gosselin, G.; Imbach. J.-L. J. Med. Chem. 1995, 38, 3941-3950.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 3941-3950
-
-
Lefebvre, I.1
Périgaud, C.2
Pompon, A.3
Aubertin, A.-M.4
Girardet, J.-L.5
Kirn, A.6
Gosselin, G.7
Imbach, J.-L.8
-
65
-
-
0029047170
-
-
(b) Lefebvre, I.; Pompon, A.; Périgaud, C.; Girardet, J.-L.; Gosselin, G.; Aubertin, A.-M.; Kirn, A.; Imbach, J.-L. Nucleosides & Nucleotides 1995, 14, 763-766.
-
(1995)
Nucleosides & Nucleotides
, vol.14
, pp. 763-766
-
-
Lefebvre, I.1
Pompon, A.2
Périgaud, C.3
Girardet, J.-L.4
Gosselin, G.5
Aubertin, A.-M.6
Kirn, A.7
Imbach, J.-L.8
-
66
-
-
0028843908
-
-
Girardet, J.-L.; Périgaud, C.; Aubertin, A.-M.; Gosselin, G.; Kirn, A.; Imbach, J.-L. Bioorg. Med. Chem. Lett. 1995, 5, 2981-2984.
-
(1995)
Bioorg. Med. Chem. Lett.
, vol.5
, pp. 2981-2984
-
-
Girardet, J.-L.1
Périgaud, C.2
Aubertin, A.-M.3
Gosselin, G.4
Kirn, A.5
Imbach, J.-L.6
-
67
-
-
0027980948
-
-
(a) Périgaud, C.; Aubertin, A.-M.; Benzaria, S.; Pelicano, H.; Girardet, J.-L.; Maury, G.; Gosselin, G.; Kirn, A.; Imbach, J.-L. Biochem. Pharmacol. 1994, 48, 11-14.
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 11-14
-
-
Périgaud, C.1
Aubertin, A.-M.2
Benzaria, S.3
Pelicano, H.4
Girardet, J.-L.5
Maury, G.6
Gosselin, G.7
Kirn, A.8
Imbach, J.-L.9
-
68
-
-
0029059414
-
-
(b) Périgaud, C.; Gosselin, G.; Benzaria, S.; Girardet, J.-L.; Maury, G.; Pélicano, H.; Aubertin, A.-M.; Kirn, A.; Imbach, J.-L. Nucleosides & Nucleotides 1995, 14, 789-791.
-
(1995)
Nucleosides & Nucleotides
, vol.14
, pp. 789-791
-
-
Périgaud, C.1
Gosselin, G.2
Benzaria, S.3
Girardet, J.-L.4
Maury, G.5
Pélicano, H.6
Aubertin, A.-M.7
Kirn, A.8
Imbach, J.-L.9
-
69
-
-
26844562002
-
-
September 15-19, La Jolla, USA
-
Schlienger, N.; Périgaud, C.; Gosselin, G.; Imbach, J.-L. Work presented at the 12th International Round Table Nucleosides, Nucleotides & their biological Application, September 15-19, 1996, La Jolla, USA.
-
(1996)
12th International Round Table Nucleosides, Nucleotides & Their Biological Application
-
-
Schlienger, N.1
Périgaud, C.2
Gosselin, G.3
Imbach, J.-L.4
-
70
-
-
26844562002
-
-
September 15-19, La Jolla, USA
-
Schlienger, N.; Périgaud, C.; Gosselin, G.; Lefebvre, I.; Pompon, A.; Aubertin, A.-M.; Kirn, A.; Imbach, J.-L. Work presented at the 12th International Round Table Nucleosides, Nucleotides & their biological Application, September 15-19, 1996, La Jolla, USA.
-
(1996)
12th International Round Table Nucleosides, Nucleotides & Their Biological Application
-
-
Schlienger, N.1
Périgaud, C.2
Gosselin, G.3
Lefebvre, I.4
Pompon, A.5
Aubertin, A.-M.6
Kirn, A.7
Imbach, J.-L.8
-
71
-
-
0029155592
-
-
Routledge, A.; Walker, I.; Freeman, S.; Hay, A.; Mahmood, N. Nucleosides & Nucleotides 1995, 14, 1545-1558.
-
(1995)
Nucleosides & Nucleotides
, vol.14
, pp. 1545-1558
-
-
Routledge, A.1
Walker, I.2
Freeman, S.3
Hay, A.4
Mahmood, N.5
-
72
-
-
0001949924
-
-
(a) Glazier, A.; Kwong, C.; Rose, J.; Buckheit, R. Antiviral Res. 1992, 17, (Suppl. 1), 66.
-
(1992)
Antiviral Res.
, vol.17
, Issue.1 SUPPL.
, pp. 66
-
-
Glazier, A.1
Kwong, C.2
Rose, J.3
Buckheit, R.4
-
73
-
-
0038210864
-
-
(b) Glazier, A.; Buckheit, R.; Yanachkova, M.; Yanachkov, I.; Wright, G.E. Antiviral Res. 1994, 19, (Suppl. 1), 57.
-
(1994)
Antiviral Res.
, vol.19
, Issue.1 SUPPL.
, pp. 57
-
-
Glazier, A.1
Buckheit, R.2
Yanachkova, M.3
Yanachkov, I.4
Wright, G.E.5
-
74
-
-
37049072276
-
-
Thomson, W.; Nicholls, D.; Irwin, W.J.; Al-Mushadani, J.S.; Freeman, S.; Karpas, A.; Petrik, J. J. Chem. Soc., Perkin Trans, 1 1993, 1239-1244.
-
(1993)
J. Chem. Soc., Perkin Trans, 1
, pp. 1239-1244
-
-
Thomson, W.1
Nicholls, D.2
Irwin, W.J.3
Al-Mushadani, J.S.4
Freeman, S.5
Karpas, A.6
Petrik, J.7
-
75
-
-
37049082916
-
-
(a) Thomson, W.; Nicholls, D.; Mitchell, A.G.; Corner, J.A.; Irwin, W.J.; Freeman, S. J. Chem. Soc., Perkin Trans, 1 1993, 2303-2308.
-
(1993)
J. Chem. Soc., Perkin Trans, 1
, pp. 2303-2308
-
-
Thomson, W.1
Nicholls, D.2
Mitchell, A.G.3
Corner, J.A.4
Irwin, W.J.5
Freeman, S.6
-
76
-
-
37049067781
-
-
(b) Mitchell, A.G.; Nicholls, D.; Irwin, W.J.; Freeman, S. J. Chem. Soc., Perkin Trans. 2 1992, 1145-1150.
-
(1992)
J. Chem. Soc., Perkin Trans. 2
, pp. 1145-1150
-
-
Mitchell, A.G.1
Nicholls, D.2
Irwin, W.J.3
Freeman, S.4
-
77
-
-
0038210865
-
-
(c) Mitchell, A.G.; Thomson, W.; Nicholls, D.; Irwin, W.J.; Freeman, S. J. Chem. Soc., Perkin Trans 1, 1992, 2345-2353.
-
(1992)
J. Chem. Soc., Perkin Trans 1
, pp. 2345-2353
-
-
Mitchell, A.G.1
Thomson, W.2
Nicholls, D.3
Irwin, W.J.4
Freeman, S.5
-
78
-
-
0030592759
-
-
Briggs, A.D.; Camplo, M.; Freeman, S.; Lundström, J.; Pring, B.C. Tetrahedron, 1996, 47, 14937-14950.
-
(1996)
Tetrahedron
, vol.47
, pp. 14937-14950
-
-
Briggs, A.D.1
Camplo, M.2
Freeman, S.3
Lundström, J.4
Pring, B.C.5
-
80
-
-
26844476410
-
-
May 19-24, in Urabandai, Fukushima, Japan
-
Glazier, A.; Yanachkova, M.; Yanachkov, I.; Wright, G.E.; Kern, E.R.; Sidwell, R.; Smee, D.; McKeough, M.; Spruance, S.L. Work presented at the 9th International Conference on Antiviral Research, May 19-24, 1996, in Urabandai, Fukushima, Japan.
-
(1996)
9th International Conference on Antiviral Research
-
-
Glazier, A.1
Yanachkova, M.2
Yanachkov, I.3
Wright, G.E.4
Kern, E.R.5
Sidwell, R.6
Smee, D.7
McKeough, M.8
Spruance, S.L.9
-
81
-
-
0030896486
-
-
McGuigan, C.; Camarasa, M.-J.; Egberink, H.; Hartmann, K.; Karlsson, A.; Perno, C.F.; Balzarini, J. Int. Antiviral News 1997, 5, 19-21.
-
(1997)
Int. Antiviral News
, vol.5
, pp. 19-21
-
-
McGuigan, C.1
Camarasa, M.-J.2
Egberink, H.3
Hartmann, K.4
Karlsson, A.5
Perno, C.F.6
Balzarini, J.7
-
82
-
-
0029975897
-
-
McGuigan, C.; Cahard, D.; Sheeka, H.M.; De Clercq, E.; Balzarini, J. J. Med. Chem. 1996, 59, 1748-1753.
-
(1996)
J. Med. Chem.
, vol.59
, pp. 1748-1753
-
-
McGuigan, C.1
Cahard, D.2
Sheeka, H.M.3
De Clercq, E.4
Balzarini, J.5
-
83
-
-
0027284753
-
-
McGuigan, C.; Pathirana, R.N.; Balzarini, J.; De Clercq, E.; J. Med. Chem. 1993, 36, 1048-1052.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 1048-1052
-
-
McGuigan, C.1
Pathirana, R.N.2
Balzarini, J.3
De Clercq, E.4
-
84
-
-
0030583270
-
-
Balzarini, J.; Wedgwood, O.M.; Kruining, J.; Pelemans, H.; Heijtink, R.; De Clercq, E.; McGuigan, C. Biochem. Biophys. Res. Commun. 1996, 225, 363-369.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.225
, pp. 363-369
-
-
Balzarini, J.1
Wedgwood, O.M.2
Kruining, J.3
Pelemans, H.4
Heijtink, R.5
De Clercq, E.6
McGuigan, C.7
-
85
-
-
0030786410
-
-
Balzarini, J.; Kruining, J.; Wedgwood, O.; Pannecouque, C.; Aquaro, S.; Perno, C.-F.; Naesens, L.; Witvrouw, M.; Heijtink, R.; De Clercq, E.; McGuigan, C. FEBS Letters 1997, 410, 324-328.
-
(1997)
FEBS Letters
, vol.410
, pp. 324-328
-
-
Balzarini, J.1
Kruining, J.2
Wedgwood, O.3
Pannecouque, C.4
Aquaro, S.5
Perno, C.-F.6
Naesens, L.7
Witvrouw, M.8
Heijtink, R.9
De Clercq, E.10
McGuigan, C.11
-
86
-
-
0030575614
-
-
McGuigan, C.; Wedgwood, O.M.; De Clercq, E.; Balzarini, J. Bioorg. Med. Chem. Lett. 1996, 6, 2359-2362.
-
(1996)
Bioorg. Med. Chem. Lett.
, vol.6
, pp. 2359-2362
-
-
McGuigan, C.1
Wedgwood, O.M.2
De Clercq, E.3
Balzarini, J.4
-
87
-
-
0006298517
-
-
Balzarini, J.; Egberink, H.; Hartmann, K.; Karlsson, A.; Perno, C.-F.; Cahard, D.; Naesens, L.; Thormar, E.; De Clercq, E.; McGuigan, C. Antiviral Res. 1996, 30, A18, 3;
-
(1996)
Antiviral Res.
, vol.30
-
-
Balzarini, J.1
Egberink, H.2
Hartmann, K.3
Karlsson, A.4
Perno, C.-F.5
Cahard, D.6
Naesens, L.7
Thormar, E.8
De Clercq, E.9
McGuigan, C.10
-
89
-
-
0030044583
-
-
McGuigan, C.; Cahard, D.; Salgado, A.; De Clercq, E.; Balzarini, J. Antiviral Chem. Chemother. 1996, 7, 31-36.
-
(1996)
Antiviral Chem. Chemother.
, vol.7
, pp. 31-36
-
-
McGuigan, C.1
Cahard, D.2
Salgado, A.3
De Clercq, E.4
Balzarini, J.5
-
90
-
-
0030872397
-
-
McGuigan, C.; Tsang, H.-W.; Cahard, D.; Turner, K.; Velazquez, S.; Salgado, A.; Bidois, L.; Naesens, L.; De Clercq, E.; Balzarini, J. Antiviral Res. 1997, 35, 195-204.
-
(1997)
Antiviral Res.
, vol.35
, pp. 195-204
-
-
McGuigan, C.1
Tsang, H.-W.2
Cahard, D.3
Turner, K.4
Velazquez, S.5
Salgado, A.6
Bidois, L.7
Naesens, L.8
De Clercq, E.9
Balzarini, J.10
-
91
-
-
0029998158
-
-
McGuigan, C.; Salgado, A.; Yarnold, C.; Harries, T.Y.; De Clercq, E.; Balzarini, J. Antiviral Chem. Chemother. 1996, 7, 184-188.
-
(1996)
Antiviral Chem. Chemother.
, vol.7
, pp. 184-188
-
-
McGuigan, C.1
Salgado, A.2
Yarnold, C.3
Harries, T.Y.4
De Clercq, E.5
Balzarini, J.6
-
92
-
-
0029946597
-
-
(a) Balzarini, J.; Karlsson, A.; Aquaro, S.; Perno, C.-F.; Cahard, D.; Naesens, L.; De Clercq, E.; McGuigan, C. Proc. Natl. Acad. Sci., USA 1996, 93, 7295-7299.
-
(1996)
Proc. Natl. Acad. Sci., USA
, vol.93
, pp. 7295-7299
-
-
Balzarini, J.1
Karlsson, A.2
Aquaro, S.3
Perno, C.-F.4
Cahard, D.5
Naesens, L.6
De Clercq, E.7
McGuigan, C.8
-
93
-
-
0029852052
-
-
(b) Balzarini, J.; Egberink, H.; Hartmann, K.; Cahard, D.; Vahlenkamp, T.; Thormar, E.; De Clercq, E.; McGuigan, C. Mol. Pharmacol. 1996, 50, 1207-1213.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 1207-1213
-
-
Balzarini, J.1
Egberink, H.2
Hartmann, K.3
Cahard, D.4
Vahlenkamp, T.5
Thormar, E.6
De Clercq, E.7
McGuigan, C.8
-
94
-
-
4243967709
-
-
Naesens, L.; Cahard, D.; Salgado, A.; Bidois, L.; De Clercq, E.; McGuigan, C.; Balzarini, J. Antiviral Res. 1997, 34, A54, 40;
-
(1997)
Antiviral Res.
, vol.34
-
-
Naesens, L.1
Cahard, D.2
Salgado, A.3
Bidois, L.4
De Clercq, E.5
McGuigan, C.6
Balzarini, J.7
-
97
-
-
0029118114
-
-
Wagner, C.R.; McIntee, E.J.; Schinazi, R.F.; Abraham, T.W. Bioorg. Med. Chem. Letters 1995, 5, 1819-1824.
-
(1995)
Bioorg. Med. Chem. Letters
, vol.5
, pp. 1819-1824
-
-
Wagner, C.R.1
McIntee, E.J.2
Schinazi, R.F.3
Abraham, T.W.4
-
98
-
-
0029851158
-
-
Abraham, T.W.; Kalman, T.I.; McIntee, E.J.; Wagner, C.R. J. Med. Chem. 1996, 39, 4569-4575.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 4569-4575
-
-
Abraham, T.W.1
Kalman, T.I.2
McIntee, E.J.3
Wagner, C.R.4
-
99
-
-
0030871081
-
-
McIntee, E.J.; Remmel, R.P.; Schinazi, R.F.; Abraham, T.W.; Wagner, C.R. J. Med. Chem. 1997, 40, 3323-3331
-
(1997)
J. Med. Chem.
, vol.40
, pp. 3323-3331
-
-
McIntee, E.J.1
Remmel, R.P.2
Schinazi, R.F.3
Abraham, T.W.4
Wagner, C.R.5
-
104
-
-
0030707857
-
-
Meier, C.; Knispel, T.; Lorey, M.; Balzarini, J. Int. Antiviral News 1997, 5, 183-185.
-
(1997)
Int. Antiviral News
, vol.5
, pp. 183-185
-
-
Meier, C.1
Knispel, T.2
Lorey, M.3
Balzarini, J.4
-
105
-
-
26844490126
-
-
University of Würzburg, unpublished results
-
Meier, C. University of Würzburg, unpublished results.
-
-
-
Meier, C.1
-
106
-
-
0031013734
-
-
(a) Meier, C.; Lorey, M.; De Clercq, E.; Balzarini, J. Bioorg. Med. Chem. Lett. 1997, 7, 99-104.
-
(1997)
Bioorg. Med. Chem. Lett.
, vol.7
, pp. 99-104
-
-
Meier, C.1
Lorey, M.2
De Clercq, E.3
Balzarini, J.4
-
107
-
-
26844462675
-
-
in press
-
(b) Meier, C.; Lorey, M.; De Clercq, E.; Balzarini, J. Nucleosides & Nucleotides 1997, 16, in press.
-
(1997)
Nucleosides & Nucleotides
, vol.16
-
-
Meier, C.1
Lorey, M.2
De Clercq, E.3
Balzarini, J.4
-
109
-
-
0030927126
-
-
Meier, C.; Knispel, T.; De Clercq, E.; Balzarini, J. Bioorg. Med. Chem. Lett. 1997, 7, 1577-1582.
-
(1997)
Bioorg. Med. Chem. Lett.
, vol.7
, pp. 1577-1582
-
-
Meier, C.1
Knispel, T.2
De Clercq, E.3
Balzarini, J.4
-
110
-
-
0025350764
-
-
Farrow, S.N.; Jones, A.S.; Kumar, A.; Walker, R.T.; Balzarini, J.; De Clercq, E. J. Med. Chem. 1990, 33, 1400-1406.
-
(1990)
J. Med. Chem.
, vol.33
, pp. 1400-1406
-
-
Farrow, S.N.1
Jones, A.S.2
Kumar, A.3
Walker, R.T.4
Balzarini, J.5
De Clercq, E.6
-
111
-
-
84988119839
-
-
Meier, C.; Habel, L.W.; Balzarini, J.; De Clercq, E. Liebigs Annalen der Chemie 1995, 2203-2208.
-
(1995)
Liebigs Annalen der Chemie
, pp. 2203-2208
-
-
Meier, C.1
Habel, L.W.2
Balzarini, J.3
De Clercq, E.4
-
113
-
-
0030811807
-
-
(b) Meier, C.; De Clercq, E.; Balzarini, J. Nucleosides & Nucleotides 1997, 16, 793-796.
-
(1997)
Nucleosides & Nucleotides
, vol.16
, pp. 793-796
-
-
Meier, C.1
De Clercq, E.2
Balzarini, J.3
-
114
-
-
0030764432
-
-
Lorey, M.; Meier, C.; De Clercq, E.; Balzarini, J. Nucleosides & Nucleotides 1997, 16, 789-792.
-
(1997)
Nucleosides & Nucleotides
, vol.16
, pp. 789-792
-
-
Lorey, M.1
Meier, C.2
De Clercq, E.3
Balzarini, J.4
|