Human immunodeficiency virus resistance to AZT in MOLT4/8 cells is associated with a lack of AZT phosphorylation and is bypassed by AZT-monophosphate SATE prodrugs

Antiviral Chemistry and Chemotherapy

Volumn 8, Issue 4, 1997, Pages 343-352

  Cinatl Jr , J ^a   Groschel B ^a   Zehner, R ^a   Cinatl, J ^a   Perigaud C ^b   Gosselin, G ^b   Imbach, J L ^b   Doerr, H W ^a  

^a GOETHE UNIVERSITY   (Germany)

^b CNRS   (France)

Author keywords

Cellular resistance; HIV; Nucleotide prodrugs; Thymidine kinase

Indexed keywords

DIDANOSINE; MESSENGER RNA; PRODRUG; THYMIDINE KINASE; ZALCITABINE; ZIDOVUDINE; ZIDOVUDINE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACCUMULATION; DRUG METABOLISM; DRUG RESISTANCE; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LYMPHOID CELL; MULTIDRUG RESISTANCE; PHOSPHORYLATION; PRIORITY JOURNAL;

EID: 1842330863     PISSN: 09563202     EISSN: None     Source Type: Journal    
DOI: 10.1177/095632029700800407     Document Type: Article

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