Expression of an LMNA-N195K variant of A-type lamins results in cardiac conduction defects and death in mice

Human Molecular Genetics

Volumn 14, Issue 15, 2005, Pages 2167-2180

  Mounkes, Leslie C ^a   Kozlov, Serguei V ^a   Rottman, Jeffrey N ^b   Stewart, Colin L ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; CONNEXIN 40; CONNEXIN 43; DESMIN; LAMIN A; LYSINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HF1B; UNCLASSIFIED DRUG;

AGING; AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CAUSE OF DEATH; CELL STRUCTURE; CONTROLLED STUDY; DEATH; ELECTROCARDIOGRAPHY MONITORING; GENE MUTATION; HEART ARRHYTHMIA; HEART CONTRACTION; HEART DEVELOPMENT; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE CONDUCTION DISTURBANCE; HOMOLOGOUS RECOMBINATION; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN VARIANT; SARCOMERE; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CARDIOMYOPATHY, DILATED; CONNEXINS; DESMIN; DISEASE MODELS, ANIMAL; FEMALE; LAMIN TYPE A; MALE; MICE; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; MYOCARDIUM; ORGAN SIZE; POINT MUTATION; TRANSCRIPTION FACTORS;

EID: 26444595257     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddi221     Document Type: Article

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