Rapid directional shift of mitochondrial DNA heteroplasmy in animal tissues by a mitochondrially targeted restriction endonuclease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 40, 2005, Pages 14392-14397

  Bayona Bafaluy, Maria Pilar ^a   Blits, Bas ^a   Battersby, Brendan J ^b   Shoubridge, Eric A ^b   Moraes, Carlos T ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Gene therapy; Mitochondria

Indexed keywords

MIFEPRISTONE; MITOCHONDRIAL DNA; PROTEIN APAL1; RESTRICTION ENDONUCLEASE; UNCLASSIFIED DRUG; VIRUS VECTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN CELL; CONTROLLED STUDY; DNA DETERMINATION; FEMALE; GENE MUTATION; HAPLOTYPE; HETEROPLASMY; IN VIVO STUDY; MALE; MITOCHONDRIAL RESPIRATION; MOUSE; MUSCLE CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN TARGETING; SYMPTOMATOLOGY; VIRUS RECOMBINANT; WILD TYPE;

ADENOVIRIDAE; ANIMALS; BLOTTING, SOUTHERN; CELL LINE; DNA RESTRICTION ENZYMES; DNA, MITOCHONDRIAL; FEMALE; GENE TARGETING; GENE THERAPY; GENETIC VECTORS; HAPLOTYPES; MICE; MICE, INBRED NZB; MITOCHONDRIAL DISEASES; MUTATION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

ANIMALIA;

EID: 26444545053     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0502896102     Document Type: Article

References (33)

1. Kaufman, B. A., Newman, S. M., Hallberg, R. L., Slaughter, C. A., Perlman, P. S. & Butow, R. A. (2000) Proc. Natl. Acad. Sci. USA 97, 7772-7777.
2. Legros, F., Malka, F., Fraction, P., Lombes, A. & Rojo, M. (2004) J. Cell Sci. 117, 2653-2662.
3. Bogenhagen, D. F., Wang, Y., Shen, E. L. & Kobayashi, R. (2003) Mol. Cell Proteomics 2, 1205-1216.
4. Garrido, N., Griparic, L., Jokitalo, E., Wartiovaara, J., van der Blick, A. M. & Spelbrink, J. N. (2003) Mol. Biol. Cell 14, 1583-1596.
5. Thorburn, D. R. & Dahl, H. H. (2001) Am. J. Med. Genet. 106, 102-114.
6. DiMauro, S. & Schon, E. A. (2003) N. Engl. J. Med. 348, 2656-2668.
7. Holt, I. J., Harding, A. E., Petty, R. K. & Morgan-Hughes, J. A. (1990) Am. J. Hum. Genet. 46, 428-433.
8. Srivastava, S. & Moraes, C. T. (2001) Hum. Mol. Genet. 10, 3093-3099.
9. Tanaka, M., Borgeld, H. J., Zhang, J., Muramatsu, S., Gong, J. S., Yoneda, M., Maruyama, W., Naoi, M., Ibi, T., Sahashi, K., et al. (2002) J. Biomed. Sci. 9, 534-541.
10. Jenuth, J. P., Peterson, A. C. & Shoubridge, E. A. (1997) Nat. Genet. 16, 93-95.
11. Battersby, B. J. & Shoubridge, E. A. (2001) Hum. Mol. Genet. 10, 2469-2479.
12. Battersby, B. J., Loredo-Osti, J. C. & Shoubridge, E. A. (2003) Nat. Genet. 33, 183-186.
13. De Giorgi, F., Ahmed, Z., Bastianutto, C, Brini, M., Jouaville, L. S., Marsault, R., Murgia, M., Pinton, P., Pozzan, T. & Rizzuto, R. (1999) Methods Cell Biol. 58, 75-85.
14. Burger, C., Gorbatyuk, O. S., Velardo, M. J., Peden, C. S., Williams, P., Zolotukhin, S., Reier, P. J., Mandel, R. J. & Muzyezka, N. (2004) Mol. Ther. 10, 302-317.
15. Rabinowitz, J. E., Rolling, F., Li, C., Conrath, H., Xiao, W., Xiao, X. & Samulski, R. J. (2002) J. Virol. 76, 791-801.
16. Santos, M. A., Moura, G., Massey, S. E. & Tuite, M. F. (2004) Trends Genet. 20, 95-102.
17. Davidson, B. L., Stein, C. S., Heth, J. A., Martins, I., Kotin, R. M., Derksen, T. A., Zabner, J., Ghodsi, A. & Chiorini, J. A. (2000) Proc. Natl. Acad. Sci. USA 97, 3428-3432.
18. Passini, M. A., Watson, D. J., Vite, C. H., Landsburg, D. J., Feigenbaum, A. L. & Wolfe, J. H. (2003) J. Virol. 77, 7034-7040.
19. Taylor, R. W., Wardeil, T. M., Lightowlers, R. N. & Turnbull, D. M. (2000) Neurol. Sci. 21, S909-S912.
20. Taylor, R. W., Chinnery, P. F., Turnbull, D. M. & Lightowlers, R. N. (1997) Nat. Genet. 15, 212-215.
21. Muratovska, A., Lightowlers, R. N., Taylor, R. W., Turnbull, D. M., Smith, R. A., Wilce, J. A., Martin, S. W. & Murphy, M. P. (2001) Nucleic Acids Res. 29, 1852-1863.
22. Shoubridge, E. A., Johns, T. & Karpati, G. (1997) Hum. Mol. Genet. 6, 2239-2242.
23. Clark, K. M., Bindoff, L. A., Lightowlers, R. N., Andrews, R. M., Griffiths, P. G., Johnson, M. A., Brierley, E. J. & Turnbull, D. M. (1997) Nat. Genet. 16, 222-224.
24. Taivassalo, T., Fu, K., Johns, T., Arnold, D., Karpati, G. & Shoubridge, E. A. (1999) Hum. Mol. Genet. 8, 1047-1052.
25. Taivassalo, T. & Haller, R. G. (2004) Biochim. Biophys. Acta 1659, 221-231.
26. Santra, S., Gilkerson, R. W., Davidson, M. & Schon, E. A. (2004) Ann. Neurol. 56, 662-669.
27. Jazayeri, M., Andreyev, A., Will, Y., Ward, M., Anderson, C. M. & Clevenger, W. (2003) J. Biol. Chem. 278, 9823-9830.
28. Sorensen, L., Ekstrand, M., Silva, J. P., Lindqvist, E., Xu, B., Rustin, P., Olson, L. & Larsson, N. G. (2001) J. Neurosci. 21, 8082-8090.
29. Amalfitano, A. (2004) Methods 33, 173-178.
30. Cao, H., Koehler, D. R. & Hu, J. (2004) Virol Immunol. 17, 327-333.
31. Monahan, P. E. & Samulski, R. J. (2000) Mol. Med. Today 6, 433-440.
32. Wang, Y., Tsai, S. Y. & O'Malley, B. W. (2000) Adv. Pharmacol. 47, 343-355.
33. Srivastava, S. & Moraes, C. T. (2005) Hum. Mol. Genet. 14, 893-902.