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Volumn 5, Issue 5, 2005, Pages 293-302

Detection of resistance to imatinib by metabolic profiling: Clinical and drug development implications

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BCR ABL PROTEIN; FATTY ACID; FK 866; GLUCOSE; IMATINIB; STABLE ISOTOPE; UNCLASSIFIED DRUG;

EID: 26444469502     PISSN: 11752203     EISSN: 11752203     Source Type: Journal    
DOI: 10.2165/00129785-200505050-00002     Document Type: Review
Times cited : (55)

References (55)
  • 2
    • 0037186924 scopus 로고    scopus 로고
    • Imatinib mesylate: A new oral targeted therapy
    • Savage DG, Antman KH. Imatinib mesylate: a new oral targeted therapy. N Engl J Med 2002; 346: 683-93
    • (2002) N Engl J Med , vol.346 , pp. 683-693
    • Savage, D.G.1    Antman, K.H.2
  • 3
    • 0030853063 scopus 로고    scopus 로고
    • The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of BCR-ABL positive cells
    • Deiniger MWN, Goldman JM, Lydon N, et al. The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of BCR-ABL positive cells. Blood 1997; 90: 3691-8
    • (1997) Blood , vol.90 , pp. 3691-3698
    • Deiniger, M.W.N.1    Goldman, J.M.2    Lydon, N.3
  • 4
    • 0035122485 scopus 로고    scopus 로고
    • Indication of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase
    • Vigneri P, Wang JY. Indication of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase. Nat Med 2001; 7: 228-34
    • (2001) Nat Med , vol.7 , pp. 228-234
    • Vigneri, P.1    Wang, J.Y.2
  • 5
    • 0030031766 scopus 로고    scopus 로고
    • Inhibition of the ABL proteintyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative
    • Buchdunger E, Zimmermann J, Mett H, et al. Inhibition of the ABL proteintyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative. Cancer Res 1996; 56: 100-4
    • (1996) Cancer Res , vol.56 , pp. 100-104
    • Buchdunger, E.1    Zimmermann, J.2    Mett, H.3
  • 6
    • 0037103624 scopus 로고    scopus 로고
    • Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta
    • Apperley JF, Gardembas M, Melo JV, et al. Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta. N Engl J Med 2002; 347: 481-7
    • (2002) N Engl J Med , vol.347 , pp. 481-487
    • Apperley, J.F.1    Gardembas, M.2    Melo, J.V.3
  • 7
    • 0037103424 scopus 로고    scopus 로고
    • Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
    • Aug 15
    • Demetri GD, von Mehren M, Blanke CD, et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 2002 Aug 15; 347 (7): 472-80
    • (2002) N Engl J Med , vol.347 , Issue.7 , pp. 472-480
    • Demetri, G.D.1    Von Mehren, M.2    Blanke, C.D.3
  • 8
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001; 344: 1031-7
    • (2001) N Engl J Med , vol.344 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3
  • 9
    • 0037186915 scopus 로고    scopus 로고
    • Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
    • published erratum appears in N Engl J Med 2002, 347: 68
    • Kantarjian H, Sawyers C, Hochhaus A, et al. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia [published erratum appears in N Engl J Med 2002, 347: 68]. N Engl J Med 2002; 346: 645-52
    • (2002) N Engl J Med , vol.346 , pp. 645-652
    • Kantarjian, H.1    Sawyers, C.2    Hochhaus, A.3
  • 10
    • 0037045583 scopus 로고    scopus 로고
    • BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukemia to STI571: A prospective study
    • Von Bubnoff N, Schneller F, Peschel C, et al. BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukemia to STI571: a prospective study. Lancet 2002; 359: 487-91
    • (2002) Lancet , vol.359 , pp. 487-491
    • Von Bubnoff, N.1    Schneller, F.2    Peschel, C.3
  • 11
    • 0035800507 scopus 로고    scopus 로고
    • Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
    • Gorre ME, Mohammed M, Ellwood K, et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001; 293: 876-80
    • (2001) Science , vol.293 , pp. 876-880
    • Gorre, M.E.1    Mohammed, M.2    Ellwood, K.3
  • 12
    • 0141528828 scopus 로고    scopus 로고
    • Chronic myeloid leukemia: Advances in biology and new approaches to treatment
    • Oct 9
    • Goldman JM, Melo JV. Chronic myeloid leukemia: advances in biology and new approaches to treatment. N Engl J Med 2003 Oct 9; 349 (15): 1451-64
    • (2003) N Engl J Med , vol.349 , Issue.15 , pp. 1451-1464
    • Goldman, J.M.1    Melo, J.V.2
  • 13
    • 0036682481 scopus 로고    scopus 로고
    • Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment
    • Roche-Lestienne C, Soenen-Cornu V, Grardel-Duflos N, et al. Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment. Blood 2002; 100: 1014-8
    • (2002) Blood , vol.100 , pp. 1014-1018
    • Roche-Lestienne, C.1    Soenen-Cornu, V.2    Grardel-Duflos, N.3
  • 14
    • 0036874198 scopus 로고    scopus 로고
    • BCR/ABL amplification in chronic myelocytic leukemia blast crisis following imatinib mesylate administration
    • Campbell LJ, Patsouris C, Rayeroux KC, et al. BCR/ABL amplification in chronic myelocytic leukemia blast crisis following imatinib mesylate administration. Cancer Genet Cytogenet 2002; 139: 30-3
    • (2002) Cancer Genet Cytogenet , vol.139 , pp. 30-33
    • Campbell, L.J.1    Patsouris, C.2    Rayeroux, K.C.3
  • 15
    • 0037443754 scopus 로고    scopus 로고
    • MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models
    • Mahon FX, Belloc F, Lagarde V, et al. MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models. Blood 2003; 101: 2368-73
    • (2003) Blood , vol.101 , pp. 2368-2373
    • Mahon, F.X.1    Belloc, F.2    Lagarde, V.3
  • 16
    • 0344305459 scopus 로고    scopus 로고
    • Overexpression of P-glycoprotein in K562 cells does not confer resistance to the growth inhibitory effects of imatinib (STI571) in vitro
    • Dec 15; Epub 2003 Jul 24
    • Ferrao PT, Frost MJ, Siah SP, et al. Overexpression of P-glycoprotein in K562 cells does not confer resistance to the growth inhibitory effects of imatinib (STI571) in vitro. Blood 2003 Dec 15; 102 (13): 4499-4503. Epub 2003 Jul 24
    • (2003) Blood , vol.102 , Issue.13 , pp. 4499-4503
    • Ferrao, P.T.1    Frost, M.J.2    Siah, S.P.3
  • 17
    • 0035895106 scopus 로고    scopus 로고
    • Restoration of sensitivity to STI571 in STI571-resistant chronic myeloid leukemia cells
    • Tipping AJ, Mahon FX, Lagarde V, et al. Restoration of sensitivity to STI571 in STI571-resistant chronic myeloid leukemia cells. Blood 2001; 98: 3864-7
    • (2001) Blood , vol.98 , pp. 3864-3867
    • Tipping, A.J.1    Mahon, F.X.2    Lagarde, V.3
  • 18
    • 0141761420 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth and induces apoptosis in BCR/ABL-positive cell lines sensitive and resistant to imatinib mesylate
    • Gatto S, Scappini B, Pham L, et al. The proteasome inhibitor PS-341 inhibits growth and induces apoptosis in BCR/ABL-positive cell lines sensitive and resistant to imatinib mesylate. Haematologica 2003; 88: 853-63
    • (2003) Haematologica , vol.88 , pp. 853-863
    • Gatto, S.1    Scappini, B.2    Pham, L.3
  • 20
    • 0034006104 scopus 로고    scopus 로고
    • Applications of magnetic resonance in model systems: Tumor biology and physiology
    • Gillies RJ, Bhujwalla ZM, Evelhoch J, et al. Applications of magnetic resonance in model systems: tumor biology and physiology. Neoplasia 2000; 2: 139-51
    • (2000) Neoplasia , vol.2 , pp. 139-151
    • Gillies, R.J.1    Bhujwalla, Z.M.2    Evelhoch, J.3
  • 21
    • 0034047595 scopus 로고    scopus 로고
    • Applications of magnetic resonance in model systems: Cancer therapeutics
    • Evelhoch JL, Gillies TJ, Karczmar GS, et al. Applications of magnetic resonance in model systems: cancer therapeutics. Neoplasia 2000; 2: 152-65
    • (2000) Neoplasia , vol.2 , pp. 152-165
    • Evelhoch, J.L.1    Gillies, T.J.2    Karczmar, G.S.3
  • 22
    • 3042823722 scopus 로고    scopus 로고
    • Metabolic profiles of cancer cells
    • Griffin JL, Shockcor JP. Metabolic profiles of cancer cells. Nat Rev Cancer 2004; 4: 551-61
    • (2004) Nat Rev Cancer , vol.4 , pp. 551-561
    • Griffin, J.L.1    Shockcor, J.P.2
  • 23
    • 0028103840 scopus 로고
    • Magnetic resonance spectroscopy detects metabolic differences between seven Dunning rat prostate tumor sublines with different biological behavior
    • Cornel EB, Heerschap A, Smits GA, et al. Magnetic resonance spectroscopy detects metabolic differences between seven Dunning rat prostate tumor sublines with different biological behavior. Prostate 1994; 25: 19-28
    • (1994) Prostate , vol.25 , pp. 19-28
    • Cornel, E.B.1    Heerschap, A.2    Smits, G.A.3
  • 24
    • 0035370169 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy of the malignant prostate gland after radiotherapy: A histopathologic study of diagnostic validity
    • Menard C, Smith IC, Somorjai RL, et al. Magnetic resonance spectroscopy of the malignant prostate gland after radiotherapy: a histopathologic study of diagnostic validity. Int J Radiat Oncol Biol Phys 2001; 50: 317-23
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , pp. 317-323
    • Menard, C.1    Smith, I.C.2    Somorjai, R.L.3
  • 25
    • 6344261877 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism
    • McKnight TR. Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism. Semin Oncol 2004; 31: 605-17
    • (2004) Semin Oncol , vol.31 , pp. 605-617
    • McKnight, T.R.1
  • 26
    • 19944418214 scopus 로고    scopus 로고
    • Preliminary assessment of magnetic resonance spectroscopic imaging in predicting treatment outcome in patients with prostate cancer at high risk for relapse
    • Dec
    • Pucar D, Koutcher JA, Shah A, et al. Preliminary assessment of magnetic resonance spectroscopic imaging in predicting treatment outcome in patients with prostate cancer at high risk for relapse. Clin Prostate Cancer 2004 Dec; 3 (3): 174-81
    • (2004) Clin Prostate Cancer , vol.3 , Issue.3 , pp. 174-181
    • Pucar, D.1    Koutcher, J.A.2    Shah, A.3
  • 27
    • 0032893756 scopus 로고    scopus 로고
    • Malignant transformation alters membrane choline phospholipids metabolism of human mammary epithelial cells
    • Aboagye EO, Bhujwalla ZM. Malignant transformation alters membrane choline phospholipids metabolism of human mammary epithelial cells. Cancer Res 1999; 59: 80-4
    • (1999) Cancer Res , vol.59 , pp. 80-84
    • Aboagye, E.O.1    Bhujwalla, Z.M.2
  • 28
    • 0036847446 scopus 로고    scopus 로고
    • Real-time changes in 1H and 31P NMR spectra of malignant human mammary epithelial cells during treatment with the anti-inflammatory agent indomethacin
    • Glunde K, Ackerstaff E, Natarajan K, et al. Real-time changes in 1H and 31P NMR spectra of malignant human mammary epithelial cells during treatment with the anti-inflammatory agent indomethacin. Magn Reson Med 2002; 48: 819-25
    • (2002) Magn Reson Med , vol.48 , pp. 819-825
    • Glunde, K.1    Ackerstaff, E.2    Natarajan, K.3
  • 29
    • 0036348367 scopus 로고    scopus 로고
    • Phosphomonoester concentrations differ between chronic lymphocytic leukemia cells and normal human lymphocytes
    • Franks SE, Smith MR, Arias-Mendoza F, et al. Phosphomonoester concentrations differ between chronic lymphocytic leukemia cells and normal human lymphocytes. Leukemia Res 2002; 26: 919-26
    • (2002) Leukemia Res , vol.26 , pp. 919-926
    • Franks, S.E.1    Smith, M.R.2    Arias-Mendoza, F.3
  • 30
    • 0033538462 scopus 로고    scopus 로고
    • Inhibition of phosphatidylcholine biosynthesis following induction of apoptosis in HL-60 cells
    • Anthony ML, Zhao M, Brindle KM. Inhibition of phosphatidylcholine biosynthesis following induction of apoptosis in HL-60 cells. J Biol Chem 1999; 274: 19686-92
    • (1999) J Biol Chem , vol.274 , pp. 19686-19692
    • Anthony, M.L.1    Zhao, M.2    Brindle, K.M.3
  • 31
    • 0032958532 scopus 로고    scopus 로고
    • Magnetic resonance detects metabolic changes associated with chemotherapy-associated apoptosis
    • Ronen SM, DiStefano F, McCoy CL, et al. Magnetic resonance detects metabolic changes associated with chemotherapy-associated apoptosis. Br J Cancer 1999; 80: 1035-41
    • (1999) Br J Cancer , vol.80 , pp. 1035-1041
    • Ronen, S.M.1    Distefano, F.2    McCoy, C.L.3
  • 32
    • 0031850986 scopus 로고    scopus 로고
    • Induction of apoptosis in two mammalian cell lines results in increased levels of fructose-1,6-biphosphate and CDP-choline as determined by 31P-MRS
    • Williams SN, Anthony ML, Brindle KM. Induction of apoptosis in two mammalian cell lines results in increased levels of fructose-1,6-biphosphate and CDP-choline as determined by 31P-MRS. Magn Reson Med 1998; 40: 411-20
    • (1998) Magn Reson Med , vol.40 , pp. 411-420
    • Williams, S.N.1    Anthony, M.L.2    Brindle, K.M.3
  • 33
    • 18244376911 scopus 로고    scopus 로고
    • Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy
    • Muruganandham M, Alfieri AA, Matei C, et al. Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy. Clin Cancer Res 2005; 11: 3503-13
    • (2005) Clin Cancer Res , vol.11 , pp. 3503-3513
    • Muruganandham, M.1    Alfieri, A.A.2    Matei, C.3
  • 34
    • 4444228712 scopus 로고    scopus 로고
    • Bone marrow transplantation in the course of hematological malignancies: Follow-up study in blood serum by 31P MRS
    • Kuliszkiewicz-Janus M, Baczynski S, Jurczyk A. Bone marrow transplantation in the course of hematological malignancies: follow-up study in blood serum by 31P MRS. Med Sci Monit 2004; 10: 485-92
    • (2004) Med Sci Monit , vol.10 , pp. 485-492
    • Kuliszkiewicz-Janus, M.1    Baczynski, S.2    Jurczyk, A.3
  • 35
    • 0035104245 scopus 로고    scopus 로고
    • Imaging biochemistry: Applications to breast cancer
    • Ronen SM, Leach MO. Imaging biochemistry: applications to breast cancer. Breast Cancer Res 2001; 3: 36-40
    • (2001) Breast Cancer Res , vol.3 , pp. 36-40
    • Ronen, S.M.1    Leach, M.O.2
  • 36
    • 0034882047 scopus 로고    scopus 로고
    • Isofenphos induced metabolic changes in K562 myeloid blast cells
    • Boros LG, Williams RD. Isofenphos induced metabolic changes in K562 myeloid blast cells. Leuk Res 2001; 25: 883-90
    • (2001) Leuk Res , vol.25 , pp. 883-890
    • Boros, L.G.1    Williams, R.D.2
  • 37
    • 0037096742 scopus 로고    scopus 로고
    • Genotoxic exposure is associated with alterations in glucose uptake and metabolism
    • Zhou R, Vander Heiden MG, Rudin CM. Genotoxic exposure is associated with alterations in glucose uptake and metabolism. Cancer Res 2002; 62: 3515-20
    • (2002) Cancer Res , vol.62 , pp. 3515-3520
    • Zhou, R.1    Vander Heiden, M.G.2    Rudin, C.M.3
  • 38
    • 0025925025 scopus 로고
    • 1H and 31P NMR and HPLC studies on mouse L1210 leukemia cell extracts: The effect of AU(I) and Cu(I) diphosphine complexes on the cell metabolism
    • Bernes-Price SJ, Sant ME, Christopherson RI, et al. 1H and 31P NMR and HPLC studies on mouse L1210 leukemia cell extracts: the effect of AU(I) and Cu(I) diphosphine complexes on the cell metabolism. Magn Reson Med 1991; 18: 142-58
    • (1991) Magn Reson Med , vol.18 , pp. 142-158
    • Bernes-Price, S.J.1    Sant, M.E.2    Christopherson, R.I.3
  • 39
    • 0037085584 scopus 로고    scopus 로고
    • Metabolic profiling of cell growth and death in cancer: Applications in drug discovery
    • Boros LG, Cascante M, Lee WN. Metabolic profiling of cell growth and death in cancer: applications in drug discovery. Drug Discov Today 2002; 7: 364-72
    • (2002) Drug Discov Today , vol.7 , pp. 364-372
    • Boros, L.G.1    Cascante, M.2    Lee, W.N.3
  • 40
    • 0036135276 scopus 로고    scopus 로고
    • A metabolic hypothesis of cell growth and death in pancreatic cancer
    • Boros LG, Lee WN, Go VL. A metabolic hypothesis of cell growth and death in pancreatic cancer. Pancreas 2002; 24: 26-33
    • (2002) Pancreas , vol.24 , pp. 26-33
    • Boros, L.G.1    Lee, W.N.2    Go, V.L.3
  • 41
    • 26444567826 scopus 로고    scopus 로고
    • [1,2-13C2]-D-glucose profiles of the serum, liver, pancreas and DMBA-induced pancreatic tumors of rats
    • In press
    • Boros LG, Lerner MR, Morgan DL, et al. [1,2-13C2]-D-glucose profiles of the serum, liver, pancreas and DMBA-induced pancreatic tumors of rats. Pancreas 2005, In press
    • (2005) Pancreas
    • Boros, L.G.1    Lerner, M.R.2    Morgan, D.L.3
  • 43
    • 0346881620 scopus 로고    scopus 로고
    • Metabolic biomarker and kinase target discovery in cancer using stable isotope-based dynamic metabolic profiling (SIDMAP)
    • Boros LG, Brackett DJ, Harrigan GG. Metabolic biomarker and kinase target discovery in cancer using stable isotope-based dynamic metabolic profiling (SIDMAP). Curr Cancer Drug Target 2003; 3: 447-55
    • (2003) Curr Cancer Drug Target , vol.3 , pp. 447-455
    • Boros, L.G.1    Brackett, D.J.2    Harrigan, G.G.3
  • 44
    • 5144225468 scopus 로고    scopus 로고
    • Imatinib (STI571)-mediated changes in glucose metabolism in human leukemia BCR-ABL positive cells
    • Gottschalk S, Anderson N, Miljus J, et al. Imatinib (STI571)-mediated changes in glucose metabolism in human leukemia BCR-ABL positive cells. Clin Cancer Res 2004; 10: 6661-8
    • (2004) Clin Cancer Res , vol.10 , pp. 6661-6668
    • Gottschalk, S.1    Anderson, N.2    Miljus, J.3
  • 46
    • 26444575466 scopus 로고    scopus 로고
    • Role of defective high-affinity thiamine transporter slc19a2 in marrow from a mouse model of thiamine-responsive anemia syndrome: Evidence for defective deoxyribose and heme synthesis
    • Dec 4-6; Atlanta (GA)
    • Sahai I, Montefusco MC, Fleming JC, et al. Role of defective high-affinity thiamine transporter slc19a2 in marrow from a mouse model of thiamine-responsive anemia syndrome: evidence for defective deoxyribose and heme synthesis. 47th American Society of Hematology Annual Meeting; 2005 Dec 4-6; Atlanta (GA).
    • (2005) 47th American Society of Hematology Annual Meeting
    • Sahai, I.1    Montefusco, M.C.2    Fleming, J.C.3
  • 47
    • 20144372598 scopus 로고    scopus 로고
    • Patupilone (epothilone B, EPO906) and imatinib (STI571, Glivec) in combination display enhanced antitumour activity in vivo against experimental rat C6 glioma
    • O'Reilly T, Wartmann M, Maira SM, et al. Patupilone (epothilone B, EPO906) and imatinib (STI571, Glivec) in combination display enhanced antitumour activity in vivo against experimental rat C6 glioma. Cancer Chemother Pharmacol 2004; 55: 307-17
    • (2004) Cancer Chemother Pharmacol , vol.55 , pp. 307-317
    • O'Reilly, T.1    Wartmann, M.2    Maira, S.M.3
  • 48
    • 26444621412 scopus 로고    scopus 로고
    • Imatinib and hydroxyurea in pretreated progressive glioblastoma multiforme: A patient series
    • Jul 20. Epub ahead of print
    • Dresemann G. Imatinib and hydroxyurea in pretreated progressive glioblastoma multiforme: a patient series. Ann Oncol 2005 Jul 20. Epub ahead of print
    • (2005) Ann Oncol
    • Dresemann, G.1
  • 49
    • 0034665138 scopus 로고    scopus 로고
    • Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class
    • Sep 15
    • Kilic T, Alberta JA, Zdunek PR, et al. Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class. Cancer Res 2000 Sep 15; 60 (18): 5143-50
    • (2000) Cancer Res , vol.60 , Issue.18 , pp. 5143-5150
    • Kilic, T.1    Alberta, J.A.2    Zdunek, P.R.3
  • 50
    • 13444263259 scopus 로고    scopus 로고
    • Accessing key steps of human tumor progression in vivo by using an avian embryo model
    • U S A, Feb 1
    • Hagedorn M, Javerzat S, Gilges D, et al. Accessing key steps of human tumor progression in vivo by using an avian embryo model. Proc Natl Acad Sci USA 2005 Feb 1; 102(5): 1643-8
    • (2005) Proc Natl Acad Sci , vol.102 , Issue.5 , pp. 1643-1648
    • Hagedorn, M.1    Javerzat, S.2    Gilges, D.3
  • 51
    • 24344482346 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of imatinib
    • Peng B, Lloyd P, Schran H. Clinical pharmacokinetics of imatinib. Clin Pharmacokinet 2005; 44 (9): 879-94
    • (2005) Clin Pharmacokinet , vol.44 , Issue.9 , pp. 879-894
    • Peng, B.1    Lloyd, P.2    Schran, H.3
  • 52
    • 0023026830 scopus 로고
    • Relationship between pyridine nucleotide levels and ribonucleotide reductase activity in Yoshida ascites hepatoma AH130
    • Dec
    • Chevanne M, Caldini R. Relationship between pyridine nucleotide levels and ribonucleotide reductase activity in Yoshida ascites hepatoma AH130. Exp Cell Res 1986 Dec; 167 (2): 327-36
    • (1986) Exp Cell Res , vol.167 , Issue.2 , pp. 327-336
    • Chevanne, M.1    Caldini, R.2
  • 53
    • 0036769690 scopus 로고    scopus 로고
    • Use of positron emission tomography (PET) in oncology and its potential role to assess response to imatinib mesylate therapy in gastrointestinal stromal tumors (GISTs)
    • Van den Abbeele AD, Balawi RD. Use of positron emission tomography (PET) in oncology and its potential role to assess response to imatinib mesylate therapy in gastrointestinal stromal tumors (GISTs). Eur J Cancer 2002; 38: S60-5
    • (2002) Eur J Cancer , vol.38
    • Van Den Abbeele, A.D.1    Balawi, R.D.2
  • 54
    • 0031854254 scopus 로고    scopus 로고
    • Gestational diabetes: Antepartum characteristics that predict postpartum glucose intolerance and type 2 diabetes in Latino women
    • Buchanan TA, Xiang A, Kjos SL, et al. Gestational diabetes: antepartum characteristics that predict postpartum glucose intolerance and type 2 diabetes in Latino women. Diabetes 1998; 47: 1302-10
    • (1998) Diabetes , vol.47 , pp. 1302-1310
    • Buchanan, T.A.1    Xiang, A.2    Kjos, S.L.3
  • 55
    • 24044519089 scopus 로고    scopus 로고
    • Hepatic de novo lipogenesis in stable low-birth-weight infants during exclusive breast milk feedings and during parenteral nutrition
    • Garg M, Bassilian S, Bell C, et al. Hepatic de novo lipogenesis in stable low-birth-weight infants during exclusive breast milk feedings and during parenteral nutrition. JPEN J Parenter Enteral Nutr 2005; 29: 81-6
    • (2005) JPEN J Parenter Enteral Nutr , vol.29 , pp. 81-86
    • Garg, M.1    Bassilian, S.2    Bell, C.3


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