Phosphomonoester concentrations differ between chronic lymphocytic leukemia cells and normal human lymphocytes

Leukemia Research

Volumn 26, Issue 10, 2002, Pages 919-926

  Franks, Suzanne E ^a   Smith, Mitchell R ^a   Arias Mendoza, Fernando ^a,b   Shaller, Calvin ^a   Padavic Shaller, Kristen ^a   Kappler, Francis ^a   Zhang, Yun ^a   Negendank, William G ^a   Brown, Truman R ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b HATCH LTD   (Canada)

Author keywords

B cell malignancies; Chronic lymphocytic leukemia; MR spectroscopy; Non hodgkin's lymphoma; Phosphomonoesters

Indexed keywords

CHLORAMBUCIL; CYCLOPHOSPHAMIDE; DOXORUBICIN; ESTER DERIVATIVE; ETHANOLAMINE; FLUDARABINE; GLYCEROPHOSPHOETHANOLAMINE; GLYCEROPHOSPHORYLCHOLINE; MITOXANTRONE; PHOSPHOETHANOLAMINE; PHOSPHOLIPID; PHOSPHORYLCHOLINE; PREDNISONE; RECOMBINANT ALPHA INTERFERON; VINCRISTINE;

ADULT; AGED; ARTICLE; BLOOD LEVEL; CANCER RADIOTHERAPY; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LEUKEMIA CELL; LYMPHOCYTE; MALE; PHOSPHOLIPID METABOLISM; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; TREATMENT OUTCOME;

ADULT; AGED; CASE-CONTROL STUDIES; ETHANOLAMINES; FEMALE; GLYCERYLPHOSPHORYLCHOLINE; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC; LYMPHOCYTES; MALE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEOTIDES; PHOSPHATIDYLETHANOLAMINES; PHOSPHOLIPIDS; PHOSPHORIC ACID ESTERS; PHOSPHORUS ISOTOPES; PHOSPHORYLCHOLINE;

EID: 0036348367     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(02)00035-8     Document Type: Article

References (55)

1. Studies of human tumors by MRS: A review
2. 31P NMR spectroscopy studies of phospholipid metabolism in human melanoma xenograft lines differing in rate of tumour cell proliferation
3. NMR. Studies of phospholipid metabolism and cell proliferation
4. TNF-induced modulations of phospholipid metabolism in human breast cancer cells
5. Cellular energetics measured by phosphorous nuclear magnetic resonance spectroscopy are not correlated with chronic nutrient deficiency in multicellular tumor spheroids
6. 31P MRS in situ
7. 31P magnetic resonance spectroscopy detection of response-predictive adenosine triphosphate decrease in irradiated radiation-induced fibrosarcoma-1 tumors
8. 31P MR spectroscopy
9. 31P NMR characterization of cellular metabolism during dexamethasone induced apoptosis in human leukemic cell lines
10. Phosphomonoester metabolism as a function of cell proliferative status and exogenous precursors
11. 31P MR spectral alterations in human hepatic tumours
12. Hyperthermic enhancement of cis-diammine-1,1-cyclobutane dicarboxylate platinum(II) cytotoxicity in human leukemia cells in vitro
13. Alterations of phospholipid metabolism by phorbol esters and fatty acids occur by different intracellular mechanisms in cultured glioma, neuroblastoma, and hybrid cells
14. Applications of magnetic resonance in model systems: Cancer therapeutics
15. In vivo studies by magnetic resonance imaging and spectroscopy of the response to tamoxifen of MCF7 human breast cancer implanted in nude mice
16. Applications of magnetic resonance in model systems: Tumor biology and physiology
17. Magnetic resonance imaging to measure therapeutic response using an orthotopic model of human pancreatic cancer
18. 31P changes as a measure of therapy response in human osteosarcomas implanted into nude mice
19. Pharmacokinetics and metabolism of a new antitumor semisynthetic ether phospholipid, 14C-labeled plasmanyl-(N-acyl)ethanolamine, in mice bearing sarcoma Mc11
20. Carcinogens stimulate phosphorylation of ethanolamine derived from increased hydrolysis of phosphatidylethanolamine in C3H/101/2 fibroblasts
21. Effect of 1,25-dihydroxyvitamin D3 on phospholipid metabolism in a clonal osteoblast-like rat osteogenic sarcoma cell line
22. Magnetic resonance detects metabolic changes associated with chemotherapy-induced apoptosis
23. Phospholipid metabolites as indicators of cancer cell function
24. Multinuclear MR investigation of the metabolic response of the murine RIF-1 tumor to 5-fluorouracil chemotherapy
25. 1 alpha, 25-Dihydroxyvitamin D3 rapidly alters phospholipid metabolism in the nuclear envelope of osteoblasts
26. 31P-magnetic resonance spectroscopy study
27. Altered phospholipid metabolism in sodium butyrate-induced differentiation of C6 glioma cells
28. 31P nuclear magnetic resonance spectroscopy, histology and cytokinetics of a xenografted hypopharynx carcinoma following treatment with cisplatin: Comparison in three sublines with increasing resistance
29. 31P-NMR study using a phosphonium analog of choline
30. Manipulation of the lipid composition of cultured animal cells
31. 31P NMR studies of cultured human tumor cells Influence of pH on phospholipid metabolite levels and the detection of cytidine 5′-diphosphate choline
32. 31P MRS in vivo in human cancer: Implications for experimental models and clinical studies
33. Metabolic characterization of human non-Hodgkin's lymphomas in vivo with the use of proton-decoupled phosphorus magnetic resonance spectroscopy
34. Histopathology and immunopathology
35. Phospholipid methylation: A biochemical signal modulating lymphocyte mitogenesis
36. Phospholipid base exchange in human leukocyte membranes: Quantitation and correlation with other phospholipid biosynthetic pathways
37. Phorbol ester selectively stimulates the phospholipase D-mediated hydrolysis of phosphatidylethanolamine in multidrug-resistant MCF-7 human breast carcinoma cells
38. 31P NMR measurements of the effects of unsaturated fatty acids on cellular phospholipid metabolism
39. 31P nuclear magnetic resonance spectroscopy in vitro and by administration of 14C-radiolabelled compounds in vivo
40. 31P magnetic resonance spectroscopy in vivo and in vitro
41. Radiotherapeutic response of Ehrlich ascites tumor cells perfused in agarose gel threads
42. 13-CIS-Retinoic acid-mediated growth inhibition of DU-145 human prostate cancer cells
43. 31P MRS study
44. 31P MR spectra from patients with hepatic lymphoma. A possible marker of liver infiltration and response to chemotherapy
45. 31P magnetic resonance spectroscopy of the human liver
46. 31P NMR spectroscopy
47. Tumour phospholipid metabolism
48. Malignant transformation alters membrane choline phospholipid metabolism of human mammary epithelial cells
49. NMR studies of phospholipid metabolism in hepatic lymphoma
50. Variations in energy and phospholipid metabolism in normal and cancer human mammary epithelial cells
51. 31P magnetic resonance spectroscopy study
52. 31P NMR spectra from human breast tumours: Variations in phospholipid metabolism
53. 31P NMR spectroscopy
54. Action of hemicholinium-3 on phospholipid metabolism in Krebs II ascites cells