메뉴 건너뛰기




Volumn 13, Issue 5, 2004, Pages 515-521

The therapeutic potential of glycine transporter-1 inhibitors

Author keywords

Dementia; Glycine; Glycine transporter 1; N methyl D aspartate; Schizophrenia

Indexed keywords

3 AMINO 1 HYDROXY 2 PYRROLIDINONE; ALX 5407; AMPHETAMINE; ATYPICAL ANTIPSYCHOTIC AGENT; CARRIER PROTEIN; CLOZAPINE; COCAINE; CYCLOSERINE; DEXTRO SERINE; GLYCINE; GLYCINE TRANSPORTER 1; GLYCYLDODECYLAMIDE; KETAMINE; LYSERGIDE; N [3 (4' FLUOROPHENYL) 3 (4' PHENYLPHENOXY)PROPYL]SARCOSINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROLEPTIC AGENT; OLANZAPINE; ORG 24598; PHENCYCLIDINE; PROTEIN INHIBITOR; PSYCHEDELIC AGENT; PSYCHOTROPIC AGENT; RISPERIDONE; SARCOSINE; UNCLASSIFIED DRUG;

EID: 2642557822     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.13.5.515     Document Type: Review
Times cited : (52)

References (46)
  • 1
    • 0001828811 scopus 로고
    • The discovery of the neurotransmitter role of glycine
    • OP Ottersen, J Storm-Mathisen (Eds), John Wiley and Sons, Chichester, UK
    • Aprison MH: The discovery of the neurotransmitter role of glycine. In: Glycine Neurotransmission. OP Ottersen, J Storm-Mathisen (Eds), John Wiley and Sons, Chichester, UK (1990):1-23.
    • (1990) Glycine Neurotransmission , pp. 1-23
    • Aprison, M.H.1
  • 2
    • 0023091647 scopus 로고
    • Glycine potentiates the NMDA response in cultured mouse brain neurons
    • Johnson JW, Ascher P: Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature (1987) 325(6104):529-531.
    • (1987) Nature , vol.325 , Issue.6104 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 3
    • 0025119185 scopus 로고
    • Ligand-gated ion channels in the brain: The amino acid receptor superfamily
    • Betz H: Ligand-gated ion channels in the brain: the amino acid receptor superfamily. Neuron (1990) 5(4):383-392.
    • (1990) Neuron. , vol.5 , Issue.4 , pp. 383-392
    • Betz, H.1
  • 4
    • 0032441894 scopus 로고    scopus 로고
    • Modulation of N-methyl-D-aspartate receptor function by glycine transport
    • Bergeron R, Meyer TM, Coyle JT, Greene RW: Modulation of N-methyl-D-aspartate receptor function by glycine transport. Proc. Natl. Acad. Sci. USA (1998) 95(26): 15730-15734.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , Issue.26 , pp. 15730-15734
    • Bergeron, R.1    Meyer, T.M.2    Coyle, J.T.3    Greene, R.W.4
  • 5
    • 0032429754 scopus 로고    scopus 로고
    • Glycine and N-methyl-D-aspartate receptors: Physiological significance and possible therapeutic applications
    • Danysz W, Parsons AC: Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications. Pharmacol. Rev. (1998) 50(4): 597-664.
    • (1998) Pharmacol. Rev. , vol.50 , Issue.4 , pp. 597-664
    • Danysz, W.1    Parsons, A.C.2
  • 6
    • 0026772797 scopus 로고
    • Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors
    • Smith KE, Borden LA, Hartig PR, Branchek T, Weinshank RL: Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors. Neuron (1992) 8(5):927-935.
    • (1992) Neuron. , vol.8 , Issue.5 , pp. 927-935
    • Smith, K.E.1    Borden, L.A.2    Hartig, P.R.3    Branchek, T.4    Weinshank, R.L.5
  • 7
    • 0027213413 scopus 로고
    • Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene
    • Borowsky B, Mezey E, Hoffman BJ: Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene. Neuron (1993) 10(5):851-863.
    • (1993) Neuron. , vol.10 , Issue.5 , pp. 851-863
    • Borowsky, B.1    Mezey, E.2    Hoffman, B.J.3
  • 8
    • 0027438311 scopus 로고
    • Cloning and expression of a spinal cord- and brain-specific glycine transporter with novel structural features
    • Liu QR, Lopez-Corcuera B, Mandiyan S, Nelson H, Nelson N: Cloning and expression of a spinal cord- and brain-specific glycine transporter with novel structural features. J. Biol. Chem. (1993) 268(30):22802-22808.
    • (1993) J. Biol. Chem. , vol.268 , Issue.30 , pp. 22802-22808
    • Liu, Q.R.1    Lopez-Corcuera, B.2    Mandiyan, S.3    Nelson, H.4    Nelson, N.5
  • 9
    • 0028348479 scopus 로고
    • Cloning of the human glycine transporter Type 1: Molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene
    • Kim KM, Kingsmore SF, Han H et al.: Cloning of the human glycine transporter Type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene. Mol. Pharmacol. (1994) 45(4):608-617.
    • (1994) Mol. Pharmacol. , vol.45 , Issue.4 , pp. 608-617
    • Kim, K.M.1    Kingsmore, S.F.2    Han, H.3
  • 10
    • 0031730364 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localisation of the gene in the human genome
    • Morrow JA, Collie IT, Dunbar DR, Walker GB, Shahid M, Hill DR: Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localisation of the gene in the human genome. FEBS Lett. (1998) 439(3):334-340.
    • (1998) FEBS Lett. , vol.439 , Issue.3 , pp. 334-340
    • Morrow, J.A.1    Collie, I.T.2    Dunbar, D.R.3    Walker, G.B.4    Shahid, M.5    Hill, D.R.6
  • 11
    • 0031753789 scopus 로고    scopus 로고
    • The family of Na+/Cl- neurotransmitter transporters
    • Nelson N: The family of Na+/Cl- neurotransmitter transporters. J. Neurochem. (1998) 71(5):1785-1803.
    • (1998) J. Neurochem. , vol.71 , Issue.5 , pp. 1785-1803
    • Nelson, N.1
  • 12
    • 0029014595 scopus 로고
    • Regional distribution and developmental variation of the glycine transporters GLYT1 and GLYT2 in the rat CNS
    • Zafra F, Gomeza J, Olivares L, Aragon C, Gimenez C: Regional distribution and developmental variation of the glycine transporters GLYT1 and GLYT2 in the rat CNS. Eur. J. Neurosci. (1995) 7(6):1342-1352.
    • (1995) Eur. J. Neurosci. , vol.7 , Issue.6 , pp. 1342-1352
    • Zafra, F.1    Gomeza, J.2    Olivares, L.3    Aragon, C.4    Gimenez, C.5
  • 14
    • 0030919910 scopus 로고    scopus 로고
    • Control of NMDA receptor activation by a glycine transporter co-expressed in Xenopus oocytes
    • Supplisson S, Bergman C: Control of NMDA receptor activation by a glycine transporter co-expressed in Xenopus oocytes. J. Neurosci. (1997) 17(12):4580-4590.
    • (1997) J. Neurosci. , vol.17 , Issue.12 , pp. 4580-4590
    • Supplisson, S.1    Bergman, C.2
  • 15
    • 0035206917 scopus 로고    scopus 로고
    • ALX 5407: A potent, selective inhibitor of the hGlyT1 glycine transporter
    • Atkinson BN, Bell SC, De Vivo M et al.: ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter. Mol. Pharmacol. (2001) 60(6):1414-1420.
    • (2001) Mol. Pharmacol. , vol.60 , Issue.6 , pp. 1414-1420
    • Atkinson, B.N.1    Bell, S.C.2    De Vivo, M.3
  • 16
    • 0035206590 scopus 로고    scopus 로고
    • N-[3-(4′-fluorophenyl)-3-(4′-phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transport
    • Aubrey KR, Vandenberg RJ: N-[3-(4′-fluorophenyl)-3-(4′-phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transport. Br. J. Pharmacol. (2001) 134(7):1429-1436.
    • (2001) Br. J. Pharmacol. , vol.134 , Issue.7 , pp. 1429-1436
    • Aubrey, K.R.1    Vandenberg, R.J.2
  • 17
    • 0041488749 scopus 로고    scopus 로고
    • Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4′-fluorophenyl)-3-(4′phenylphenoxy)propyl] )sarcosine
    • Mallorga PJ, Williams JB, Jacobson M et al.: Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4′-fluorophenyl)-3-(4′phenylphenoxy)propyl] sarcosine. Neuropharmacology (2003) 45(5):585-593.
    • (2003) Neuropharmacology , vol.45 , Issue.5 , pp. 585-593
    • Mallorga, P.J.1    Williams, J.B.2    Jacobson, M.3
  • 18
    • 0032415129 scopus 로고    scopus 로고
    • Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses
    • Berger AJ, Dieudonne S, Ascher P: Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses. J. Neurophysiol. (1998) 80(6):3336-3340.
    • (1998) J. Neurophysiol. , vol.80 , Issue.6 , pp. 3336-3340
    • Berger, A.J.1    Dieudonne, S.2    Ascher, P.3
  • 19
    • 0041920952 scopus 로고    scopus 로고
    • The glycine transporter Type 1 inhibitor N-[3-(4′-fluorophenyl)-3-(4′-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior
    • Kinney GG, Sur C, Burno M et al.: The glycine transporter Type 1 inhibitor N-[3-(4′-fluorophenyl)-3-(4′-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior. J. Neurosci. (2003) 23(20):7586-7591.
    • (2003) J. Neurosci. , vol.23 , Issue.20 , pp. 7586-7591
    • Kinney, G.G.1    Sur, C.2    Burno, M.3
  • 20
    • 0037320805 scopus 로고    scopus 로고
    • Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo
    • Chen L, Muhlhauser M, Yang CR: Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo. J. Neurophysiol. (2003) 89(2):691-703.
    • (2003) J. Neurophysiol. , vol.89 , Issue.2 , pp. 691-703
    • Chen, L.1    Muhlhauser, M.2    Yang, C.R.3
  • 21
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt DC, Zukin SR: Recent advances in the phencyclidine model of schizophrenia. Am. J. Psychiatry. (1991) 148(10):1301-1308.
    • (1991) Am. J. Psychiatry , vol.148 , Issue.10 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 22
    • 0013085913 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor-coupled glycineB receptors in the pathogenesis and treatment of schizophrenia: A critical review
    • Millan MJ: N-methyl-D-aspartate receptor-coupled glycineB receptors in the pathogenesis and treatment of schizophrenia: a critical review. Curr. Drug. Target CNS Neurol. Disord. (2002) 1(2):191-213.
    • (2002) Curr. Drug. Target CNS Neurol. Disord. , vol.1 , Issue.2 , pp. 191-213
    • Millan, M.J.1
  • 23
    • 0032694066 scopus 로고    scopus 로고
    • NMDA receptor hypofunction model of schizophrenia
    • Olney JW, Newcomer JW, Farber NB: NMDA receptor hypofunction model of schizophrenia. J. Psychiatr. Res. (1999) 33(6):523-533.
    • (1999) J. Psychiatr. Res. , vol.33 , Issue.6 , pp. 523-533
    • Olney, J.W.1    Newcomer, J.W.2    Farber, N.B.3
  • 24
    • 0022611408 scopus 로고
    • Antagonism of phencyclidine-induced hyperactivity by glycine in mice
    • Toth E, Lajtha A: Antagonism of phencyclidine-induced hyperactivity by glycine in mice. Neurochem. Res. (1986) 11(3):393-400.
    • (1986) Neurochem. Res. , vol.11 , Issue.3 , pp. 393-400
    • Toth, E.1    Lajtha, A.2
  • 25
    • 0030811293 scopus 로고    scopus 로고
    • Reversal of phencyclidine-induced hyperactivity by glycine and the glycine uptake inhibitor glycyldodecylamide
    • Javitt DC, Sershen H, Hashim A, Lajtha A: Reversal of phencyclidine-induced hyperactivity by glycine and the glycine uptake inhibitor glycyldodecylamide. Neuropsychopharmacology (1997) 17(3):202-204.
    • (1997) Neuropsychopharmacology , vol.17 , Issue.3 , pp. 202-204
    • Javitt, D.C.1    Sershen, H.2    Hashim, A.3    Lajtha, A.4
  • 26
    • 0030831423 scopus 로고    scopus 로고
    • Genetics, haloperidol-induced catalepsy and haloperidol-induced changes in acoustic startle and prepulse inhibition
    • McCaughran J, Mahjubi E, Decena E, Hitzemann R: Genetics, haloperidol-induced catalepsy and haloperidol-induced changes in acoustic startle and prepulse inhibition. Psychopharmacology (1997) 134(2):131-139.
    • (1997) Psychopharmacology , vol.134 , Issue.2 , pp. 131-139
    • McCaughran, J.1    Mahjubi, E.2    Decena, E.3    Hitzemann, R.4
  • 27
    • 2642537935 scopus 로고    scopus 로고
    • Development and characterization of GlyT1-selective glycine reuptake inhibitors
    • American College of Neuropsychopharmacology 40th Annual Meeting. Waikoloa, Hawaii
    • Klitenick MA, Atkinson BN, Baker DA et al.: Development and characterization of GlyT1-selective glycine reuptake inhibitors. American College of Neuropsychopharmacology 40th Annual Meeting. Waikoloa, Hawaii (2001).
    • (2001)
    • Klitenick, M.A.1    Atkinson, B.N.2    Baker, D.A.3
  • 28
    • 0344430085 scopus 로고    scopus 로고
    • Prepulse inhibition deficits of the startle reflex in neonatal ventral hippocampal-lesioned rats: Reversal by glycine and a glycine transporter inhibitor
    • Le Pen G, Kew J, Alberati D, Borroni E, Heitz MP, Moreau JL: Prepulse inhibition deficits of the startle reflex in neonatal ventral hippocampal-lesioned rats: reversal by glycine and a glycine transporter inhibitor. Biol. Psychiatry (2003) 54(11):1162-1170.
    • (2003) Biol. Psychiatry , vol.54 , Issue.11 , pp. 1162-1170
    • Le Pen, G.1    Kew, J.2    Alberati, D.3    Borroni, E.4    Heitz, M.P.5    Moreau, J.L.6
  • 29
    • 0027429353 scopus 로고
    • Delayed effects of neonatal hippocampal damage on haloperidol-induced catalepsy and apomorphine-induced stereotypic behaviors in the rat
    • Lipska BK, Weinberger DR: Delayed effects of neonatal hippocampal damage on haloperidol-induced catalepsy and apomorphine-induced stereotypic behaviors in the rat. Brain Res. Dev. Brain Res. (1993) 75(2):213-222.
    • (1993) Brain Res. Dev. Brain Res. , vol.75 , Issue.2 , pp. 213-222
    • Lipska, B.K.1    Weinberger, D.R.2
  • 30
    • 1942539345 scopus 로고    scopus 로고
    • Plasma glycine and serine levels in schizophrenia compared to normal controls and major depression: Relation to negative symptoms
    • Sumioshi T, Anil AE, Jin D, Jayathilake K, Lee M, Meltzer HY: Plasma glycine and serine levels in schizophrenia compared to normal controls and major depression: relation to negative symptoms. Int. J. Neuropsychopharmacol. (2004) 7(1):1-8.
    • (2004) Int. J. Neuropsychopharmacol. , vol.7 , Issue.1 , pp. 1-8
    • Sumioshi, T.1    Anil, A.E.2    Jin, D.3    Jayathilake, K.4    Lee, M.5    Meltzer, H.Y.6
  • 32
    • 0029658545 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled, crossover trial of glycine adjuvant therapy for treatment-resistant schizophrenia
    • Heresco-Levy U, Javitt D, Ermilov M, Mordel C, Horowitz A, Kelly D: Double-blind, placebo-controlled, crossover trial of glycine adjuvant therapy for treatment-resistant schizophrenia. Br. J. Psychiatry (1996) 169(5):610-617
    • (1996) Br. J. Psychiatry , vol.169 , Issue.5 , pp. 610-617
    • Heresco-Levy, U.1    Javitt, D.2    Ermilov, M.3    Mordel, C.4    Horowitz, A.5    Kelly, D.6
  • 33
    • 0035218449 scopus 로고    scopus 로고
    • Adjunctive high-dose glycine in the treatment of schizophrenia
    • Javitt DC, Silipo G, Cienfuegos A et al.: Adjunctive high-dose glycine in the treatment of schizophrenia. Int. J. Neuropsychopharmacol. (2001) 4(4):385-391.
    • (2001) Int. J. Neuropsychopharmacol. , vol.4 , Issue.4 , pp. 385-391
    • Javitt, D.C.1    Silipo, G.2    Cienfuegos, A.3
  • 35
    • 1442333154 scopus 로고    scopus 로고
    • High-dose glycine added to olanzapine and risperidone for the treatment of schizophrenia
    • Heresco-Levy U, Ermilov M, Lichtenberg P, Bar G, Javitt DC: High-dose glycine added to olanzapine and risperidone for the treatment of schizophrenia. Biol. Psychiatry (2004) 55(2):165-171.
    • (2004) Biol. Psychiatry , vol.55 , Issue.2 , pp. 165-171
    • Heresco-Levy, U.1    Ermilov, M.2    Lichtenberg, P.3    Bar, G.4    Javitt, D.C.5
  • 36
    • 1542617755 scopus 로고    scopus 로고
    • Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia
    • Tsai G, Lane H, Young PJ, Lane N, Chong M: Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia. Biol. Psychiatry (2004) I55(5):452-456.
    • (2004) Biol. Psychiatry , vol.I55 , Issue.5 , pp. 452-456
    • Tsai, G.1    Lane, H.2    Young, P.J.3    Lane, N.4    Chong, M.5
  • 37
    • 0037343294 scopus 로고    scopus 로고
    • The glycine transporter-1 inhibitors NFPS and Org 24461: A pharmacological study
    • Harsing LG Jr, Gacsalyi I, Szabo G et al.: The glycine transporter-1 inhibitors NFPS and Org 24461: a pharmacological study. Pharmacol. Biochem. Behav. (2003) 74(4):811-825.
    • (2003) Pharmacol. Biochem. Behav. , vol.74 , Issue.4 , pp. 811-825
    • Harsing Jr., L.G.1    Gacsalyi, I.2    Szabo, G.3
  • 38
    • 2642551804 scopus 로고    scopus 로고
    • Antipsychotic potential of the GlyT-1 inhibitor NFPS
    • Society for Neuroscience 2002 Annual Meeting. Washington, DC
    • Didriksen M, Hertel P, Mork A: Antipsychotic potential of the GlyT-1 inhibitor NFPS. Society for Neuroscience 2002 Annual Meeting. Washington, DC (2002).
    • (2002)
    • Didriksen, M.1    Hertel, P.2    Mork, A.3
  • 39
    • 2642518292 scopus 로고    scopus 로고
    • Blockade of the glycine transporter Type 1 enhances hippocampal LTP
    • Society for Neuroscience 2003 Annual Meeting. Washington, DC
    • Gorfinkel Y, Martina M, Schmidt CJ, Bergeron R: Blockade of the glycine transporter Type 1 enhances hippocampal LTP. Society for Neuroscience 2003 Annual Meeting. Washington, DC (2003).
    • (2003)
    • Gorfinkel, Y.1    Martina, M.2    Schmidt, C.J.3    Bergeron, R.4
  • 41
    • 0033015134 scopus 로고    scopus 로고
    • Improved cognition in Alzheimer's disease with short-term D-cycloserine treatment
    • Tsai GE, Falk WE, Gunther J, Coyle JT: Improved cognition in Alzheimer's disease with short-term D-cycloserine treatment. Am. J. Psychiatry. (1999) 156(3):467-469.
    • (1999) Am. J. Psychiatry , vol.156 , Issue.3 , pp. 467-469
    • Tsai, G.E.1    Falk, W.E.2    Gunther, J.3    Coyle, J.T.4
  • 42
    • 10744221393 scopus 로고    scopus 로고
    • Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition
    • Gomeza J, Hulsmann S, Ohno K et al.: Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition. Neuron (2003) 40(4):785-796.
    • (2003) Neuron. , vol.40 , Issue.4 , pp. 785-796
    • Gomeza, J.1    Hulsmann, S.2    Ohno, K.3
  • 43
    • 0348140638 scopus 로고    scopus 로고
    • Active release of glycine or D-serine saturates the glycine site of NMDA receptors at the cerebellar mossy fibre to granule cell synapse
    • Billups D, Attwell D: Active release of glycine or D-serine saturates the glycine site of NMDA receptors at the cerebellar mossy fibre to granule cell synapse. Eur. J. Neurosci. (2003) 18(11):2975-8290.
    • (2003) Eur. J. Neurosci. , vol.18 , Issue.11 , pp. 2975-8290
    • Billups, D.1    Attwell, D.2
  • 44
    • 0035102496 scopus 로고    scopus 로고
    • Amino acids and their transporters in the retina
    • Pow DV: Amino acids and their transporters in the retina. Neurochem. Int. (2001) 38(6):463-484.
    • (2001) Neurochem. Int. , vol.38 , Issue.6 , pp. 463-484
    • Pow, D.V.1
  • 45
    • 0035817222 scopus 로고    scopus 로고
    • Discovery and SAR of org 24598-a selective glycine uptake inhibitor
    • Brown A, Carlyle I, Clark J et al.: Discovery and SAR of org 24598-a selective glycine uptake inhibitor. Bioorg. Med. Chem. Lett. (2001) 11(15):2007-2009.
    • (2001) Bioorg. Med. Chem. Lett. , vol.11 , Issue.15 , pp. 2007-2009
    • Brown, A.1    Carlyle, I.2    Clark, J.3
  • 46
    • 0037424694 scopus 로고    scopus 로고
    • [3H]-(R)-NPTS, a radioligand for the Type 1 glycine transporter
    • Lowe JA 3rd, Drozda SE, Fisher K et al.: [3H]-(R)-NPTS, a radioligand for the Type 1 glycine transporter. Bioorg. Med. Chem. Lett. (2003) 13(7):1291-1292.
    • (2003) Bioorg. Med. Chem. Lett. , vol.13 , Issue.7 , pp. 1291-1292
    • Lowe III, J.A.1    Drozda, S.E.2    Fisher, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.