Selective alteration of gene expression in response to natural and synthetic retinoids

BMC Pharmacology

Volumn 2, Issue , 2002, Pages

  Brand, Céline ^a   Ségard, Pascaline ^a   Plouvier, Pascal ^a   Formstecher, Pierre ^a   Danzé, Pierre Marie ^a   Lefebvre, Philippe ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DNA; ESTROGEN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR GAMMA; RETINOID DERIVATIVE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL DIFFERENTIATION; CELL STRAIN; CORRELATION ANALYSIS; DIFFERENTIAL DISPLAY; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG TARGETING; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN TARGETING; REPORTER GENE; UNINDEXED SEQUENCE; UTERINE CERVIX CANCER;

EID: 2642541785     PISSN: 14712210     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2210-2-13     Document Type: Article

References (41)

1. Lingen MW, Polverini PJ, Bouck NP: Retinoic acid and interferon alpha act synergistically as antiangiogenic and antitumor agents against human head and neck squamous cell carcinoma. Cancer Res 1998, 58:5551-5558
2. Wu Q, Dawson MI, Zheng Y, Hobbs PD, Agadir A, Jong L, et al: Inhibition of trans-retinoic acid-resistant human breast cancer cell growth by retinoid X receptor-selective retinoids. Mol Cell Biol 1997, 17:6598-6608
3. Li Y, Lin B, Agadir A, Liu R, Dawson MI, Reed JC, et al: Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines. Mol Cell Biol 1998, 18:4719-4731
4. Rachez C, Freedman LP: Mechanisms of gene regulation by vitamin D-3 receptor: a network of coactivator interactions. Gene 2000, 246:9-21
5. Caelles C, GonzalezSancho JM, Munoz A: Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway. Genes & Develop 1997, 11:3351-3364
6. Lee HY, Walsh GL, Dawson MI, Hong WK, Kurie JM: All-transretinoic acid inhibits jun N-terminal kinase-dependent signaling pathways. J Biol Chem 1998, 273:7066-7071
7. Kamei Y, Xu L, Heinzel T, Torchia J, Kurokawa R, Gloss B, et al: A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 1996, 85:403-414
8. Zhou XF, Shen XQ, Shemshedini L: Ligand-activated retinoic acid receptor inhibits AP-1 transactivation by disrupting c-Jun/c-Fos dimerization. Mol Endocrinol 1999, 13:276-285
9. Lefebvre B, Rachez C, Formstecher P, Lefebvre P: Structural determinants of the ligand-binding site of the human retinoic acid receptor alpha. Biochemistry 1995, 34:5477-5485
10. Lefebvre B, Mouchon A, Formstecher P, Lefebvre P: H11-H12 Loop Retinoic Acid Receptor Mutants Exhibit Distinct trans-Activating and trans-Repressing Activities in the Presence of Natural or Synthetic Retinoids. Biochemistry 1998, 37:9240-9249
11. Mouchon A, Delmotte M-H, Formstecher P, Lefebvre P: Allosteric Regulation Of The Discriminative Responsiveness of Retinoic Acid Receptor to Natural and Synthetic Ligands By Retinoid X Receptor And DNA. Mol Cell Biol 1999, 19:3073-3085
12. La Vista-Picard N, Hobbs PD, Pfahl M, Dawson MI: The receptor-DNA complex determines the retinoid response: a mechanism for the diversification of the ligand signal. Mol Cell Biol 1996, 16(8):4137-4146
13. Pfahl M, Apfel R, Bendik I, Fanjul A, Graupner G, Lee MO, et al: Nuclear retinoid receptors and their mechanism of action. Vitamins and Hormones, Vol 49 1994, 49:327-382
14. Kawasaki H, Eckner R, Yao T-P, Taira K, Chiu R, Livingston DM, et al: Distinct roles of the co-activators p300 and CBP in retinoicacid-induced F9 cell differentiation. Nature 1998, 393:284-289
15. Liang P, Pardee AB: Differential display. A general protocol. Mol Biotechnol 1998, 10:261-267
16. Anzick SL, Kononen J, Walker RL, Azorsa DO, Tanner MM, Guan XY, et al: AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science 1997, 277:965-968
17. Chakravarti D, LaMorte VJ, Nelson MC, Nakajima T, Schulman IG, Juguilon H, et al: Role of CBP/p300 in nuclear receptor signalling. Nature 1996, 383:99-103
18. Eckner R, Arany Z, Ewen M, Sellers W, Livingston DM: The adenovirus E1A-associated 300-kD protein exhibits properties of a transcriptional coactivator and belongs to an evolutionarily conserved family. Cold Spring Harb Symp Quant Biol 1994, 59:85-95
19. Torchia J, Rose DW, Inostroza J, Kamei Y, Westin S, Glass CK, et al: The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature 1997, 387:677-684
20. Li H, Gomes PJ, Chen JD: RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2. Proc Natl Acad Sci U S A 1997, 94:8479-8484
21. Cavailles V, Dauvois S, Lhorset F, Lopez G, Hoare S, Kushner PJ, et al: Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor. EMBO J 1995, 14:3741-3751
22. Yao TP, Ku G, Zhou N, Scully R, Livingston DM: The nuclear hormone receptor coactivator SRC-1 is a specific target of p300. Proc Natl Acad Sci U S A 1996, 93:10626-10631
23. Thenot S, Henriquet C, Rochefort H, Cavailles V: Differential interaction of nuclear receptors with the putative human transcriptional coactivator hTIF1. J Biol Chem 1997, 272:12062-12068
24. Voegel JJ, Heine MJ, Zechel C, Chambon P, Gronemeyer H: TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors. EMBO J 1997, 15:3667-3675
25. Lee JW, Ryan F, Swaffield JC, Johnston SA, Moore DD: Interaction of thyroid-hormone receptor with a conserved transcriptional mediator. Nature 1995, 374:91-94
26. Rachez C, Suldan Z, Ward J, Chang CPB, Burakov D, Erdjumentbromage H, et al: A novel protein complex that interacts with the vitamin D-3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system. Genes & Develop 1998, 12:1787-1800
27. Horlein AJ, Naar AM, Heinzel T, Torchia J, Gloss B, Kurokawa R, et al: Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature 1995, 377:397-404
28. Chen JD, Umesono K, Evans RM: SMRT isoforms mediate repression and anti-repression of nuclear receptors heterodimers. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:7567-7571
29. Bernardini S, Melino G, Saura F, AnnicchiaricoPetruzzelli M, Motti C, Cortese C, et al: Expression of co-factors (SMRT and Trip-1) for retinoic acid receptors in human neuroectodermal cell lines. Biochem Biophys Res Commun 1997, 234:278-282
30. Lefebvre P, Mouchon A, Lefebvre B, Formstecher P: Binding of retinoic acid receptor heterodimers to DNA - A role for histones NH2 termini. J Biol Chem 1998, 273:12288-12295
31. Klein ES, Pino ME, Johnson AT, Davies PJ, Nagpal S, Thacher SM, et al: Identification and functional separation of retinoic acid receptor neutral antagonists and inverse agonists. J Biol Chem 1996, 271:22692-22696
32. Martin B, Bernardon JM, Cavey MT, Bernard B, Carlavan I, Charpentier B, et al: Selective synthetic ligands for human nuclear retinoic acid receptors. Skin Pharmacol 1992, 5:57-65
33. Strickland S, Mahdavi V: The induction of differentiation in teratocarcinoma stem cells by retinoic acid. Cell 1978, 15:393-403
34. Liu TX, Zhang JW, Tao J, Zhang RB, Zhang QH, Zhao CJ, et al: Gene expression networks underlying retinoic acid-induced differentiation of acute promyelocytic leukemia cells. Blood 2000, 96:1496-1504
35. Harrison PM, Arosio P: The ferritins: molecular properties, iron storage function and cellular regulation. Biochim Biophys Acta 1996, 1275:161-203
36. McBurney MW: P19 embryonal carcinoma cells. Int J Dev Biol 1993, 37:135-140
37. Bain G, Ray WJ, Yao M, Gottlieb DI: From embryonal carcinoma cells to neurons: the P19 pathway. Bioessays 1994, 16:343-348
38. Durand B, Saunders M, Leroy P, Leid M, Chambon P: All-trans and 9-cis Retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs. Cell 1992, 71:73-85
39. Bouillet P, Oulad-Abdelghani M, Vicaire S, Garnier JM, Schuhbaur B, Dolle P, et al: Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/ Eplg2). Dev Biol 1995, 170:420-433
40. Diaz BV, Lenoir MC, Ladoux A, Frelin C, Demarchez M, Michel S: Regulation of vascular endothelial growth factor expression in human keratinocytes by retinoids. J Biol Chem 2000, 275:642-650
41. Thacher SM, Vasudevan J, Chandraratna RA: Therapeutic applications for ligands of retinoid receptors. Curr Pharm Des 2000, 6:25-58