-
1
-
-
0025665136
-
Retinoic acid and synthetic analogs differentially activate retinoic acid receptor dependent transcription
-
Aström, A., U. Pettersson, A. Krust, P. Chambon, and J. J. Voorhees. 1990. Retinoic acid and synthetic analogs differentially activate retinoic acid receptor dependent transcription. Biochem. Biophys. Res. Commun. 173:339-345.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.173
, pp. 339-345
-
-
Aström, A.1
Pettersson, U.2
Krust, A.3
Chambon, P.4
Voorhees, J.J.5
-
2
-
-
0030480969
-
The CBP co-activator is a histone acetyltransferase
-
Bannister, A. J., and T. Kouzarides. 1996. The CBP co-activator is a histone acetyltransferase. Nature 384:641-643.
-
(1996)
Nature
, vol.384
, pp. 641-643
-
-
Bannister, A.J.1
Kouzarides, T.2
-
3
-
-
2642662483
-
The histone acetylase P/CAF is a nuclear receptor coactivator
-
Blanco, J. C. G., S. Minucci, J. M. Lu, X. J. Yang, K. K. Walker, H. W. Chen, R. M. Evans, Y. Nakatani, and K. Ozato. 1998. The histone acetylase P/CAF is a nuclear receptor coactivator. Genes Dev. 12:1638-1651.
-
(1998)
Genes Dev.
, vol.12
, pp. 1638-1651
-
-
Blanco, J.C.G.1
Minucci, S.2
Lu, J.M.3
Yang, X.J.4
Walker, K.K.5
Chen, H.W.6
Evans, R.M.7
Nakatani, Y.8
Ozato, K.9
-
4
-
-
0029012163
-
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha
-
Bourguet, W., M. Ruff, P. Chambon, H. Gronemeyer, and D. Moras. 1995. Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha. Nature 375:377-382.
-
(1995)
Nature
, vol.375
, pp. 377-382
-
-
Bourguet, W.1
Ruff, M.2
Chambon, P.3
Gronemeyer, H.4
Moras, D.5
-
5
-
-
0030667676
-
Molecular basis of agonism and antagonism in the oestrogen receptor
-
Brzozowski, A. M., A. C. W. Pike, Z. Dauter, R. E. Hubbard, T. Bonn, O. Engstrom, L. Ohman, G. L. Greene, J. A. Gustafsson, and M. Carlquist. 1997. Molecular basis of agonism and antagonism in the oestrogen receptor. Nature 389:753-758.
-
(1997)
Nature
, vol.389
, pp. 753-758
-
-
Brzozowski, A.M.1
Pike, A.C.W.2
Dauter, Z.3
Hubbard, R.E.4
Bonn, T.5
Engstrom, O.6
Ohman, L.7
Greene, G.L.8
Gustafsson, J.A.9
Carlquist, M.10
-
6
-
-
0029121358
-
Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor
-
Cavailles, V., S. Dauvois, F. Lhorset, G. Lopez, S. Hoare, P. J. Kushner, and M. G. Parker. 1995. Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor. EMBO J. 14:3741-3751.
-
(1995)
EMBO J.
, vol.14
, pp. 3741-3751
-
-
Cavailles, V.1
Dauvois, S.2
Lhorset, F.3
Lopez, G.4
Hoare, S.5
Kushner, P.J.6
Parker, M.G.7
-
7
-
-
0029097233
-
A transcriptional co-repressor that interacts with nuclear hormone receptors
-
Chen, J. D., and R. M. Evans. 1995. A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377:454-457.
-
(1995)
Nature
, vol.377
, pp. 454-457
-
-
Chen, J.D.1
Evans, R.M.2
-
8
-
-
0029781068
-
Two distinct actions of retinoid-receptor ligands
-
Chen, J. Y., J. Clifford, C. Zusi, J. Starrett, D. Tortolani, J. Ostrowski, P. R. Reczek, P. Chambon, and H. Gronemeyer. 1996. Two distinct actions of retinoid-receptor ligands. Nature 382:819-822.
-
(1996)
Nature
, vol.382
, pp. 819-822
-
-
Chen, J.Y.1
Clifford, J.2
Zusi, C.3
Starrett, J.4
Tortolani, D.5
Ostrowski, J.6
Reczek, P.R.7
Chambon, P.8
Gronemeyer, H.9
-
9
-
-
0030697963
-
Specific and redundant functions of retinoid X receptor/retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells
-
Chiba, H., J. Clifford, D. Metzger, and P. Chambon. 1997. Specific and redundant functions of retinoid X receptor/retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells. J. Cell Biol. 139:735-747.
-
(1997)
J. Cell Biol.
, vol.139
, pp. 735-747
-
-
Chiba, H.1
Clifford, J.2
Metzger, D.3
Chambon, P.4
-
10
-
-
0032213219
-
Structure and specificity of nuclear receptor-coactivator interactions
-
Darimont, B. D., R. L. Wagner, J. W. Apriletti, M. R. Stallcup, P. J. Kushner, J. D. Baxter, R. J. Fletterick, and K. R. Yamamoto. 1998. Structure and specificity of nuclear receptor-coactivator interactions. Genes Dev. 12:3343-3356.
-
(1998)
Genes Dev.
, vol.12
, pp. 3343-3356
-
-
Darimont, B.D.1
Wagner, R.L.2
Apriletti, J.W.3
Stallcup, M.R.4
Kushner, P.J.5
Baxter, J.D.6
Fletterick, R.J.7
Yamamoto, K.R.8
-
11
-
-
0026075361
-
Selective high affinity retinoic acid receptor alpha or beta-gamma ligands
-
Delescluse, C., M. T. Cavey, B. Martin, B. A. Bernard, U. Reichert, J. Maignan, M. Darmon, and B. Shroot. 1991. Selective high affinity retinoic acid receptor alpha or beta-gamma ligands. Mol. Pharmacol. 40:556-562.
-
(1991)
Mol. Pharmacol.
, vol.40
, pp. 556-562
-
-
Delescluse, C.1
Cavey, M.T.2
Martin, B.3
Bernard, B.A.4
Reichert, U.5
Maignan, J.6
Darmon, M.7
Shroot, B.8
-
12
-
-
85038183105
-
-
Unpublished data
-
Depoix, C. Unpublished data.
-
-
-
Depoix, C.1
-
13
-
-
0027941792
-
Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: Presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity
-
Durand, B., M. Saunders, C. Gaudon, B. Roy, R. Losson, and P. Chambon. 1994. Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity. EMBO J. 13:5370-5382.
-
(1994)
EMBO J.
, vol.13
, pp. 5370-5382
-
-
Durand, B.1
Saunders, M.2
Gaudon, C.3
Roy, B.4
Losson, R.5
Chambon, P.6
-
14
-
-
0026688440
-
All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs
-
Durand, B., M. Saunders, P. Leroy, M. Leid, and P. Chambon. 1992. All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs. Cell 71:73-85.
-
(1992)
Cell
, vol.71
, pp. 73-85
-
-
Durand, B.1
Saunders, M.2
Leroy, P.3
Leid, M.4
Chambon, P.5
-
15
-
-
0032511086
-
Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors
-
Feng, W. J., R. C. J. Ribeiro, R. L. Wagner, H. Nguyen, J. W. Apriletti, R. J. Fletterick, J. D. Baxter, P. J. Kushner, and B. L. West. 1998. Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors. Science 280:1747-1749.
-
(1998)
Science
, vol.280
, pp. 1747-1749
-
-
Feng, W.J.1
Ribeiro, R.C.J.2
Wagner, R.L.3
Nguyen, H.4
Apriletti, J.W.5
Fletterick, R.J.6
Baxter, J.D.7
Kushner, P.J.8
West, B.L.9
-
16
-
-
0031033980
-
Suprabasal expression of a dominant-negative RXR alpha mutant in transgenic mouse epidermis impairs regulation of gene transcription and basal keratinocyte proliferation by RAR-selective retinoids
-
Feng, X., Z. H. Peng, W. Di, X. Y. Li, C. Rochette-Egly, P. Chambon, J. J. Voorhees, and J. H. Xiao. 1997. Suprabasal expression of a dominant-negative RXR alpha mutant in transgenic mouse epidermis impairs regulation of gene transcription and basal keratinocyte proliferation by RAR-selective retinoids. Genes Dev. 11:59-71.
-
(1997)
Genes Dev.
, vol.11
, pp. 59-71
-
-
Feng, X.1
Peng, Z.H.2
Di, W.3
Li, X.Y.4
Rochette-Egly, C.5
Chambon, P.6
Voorhees, J.J.7
Xiao, J.H.8
-
17
-
-
0030986236
-
A signature motif in transcriptional co-activators mediates binding to nuclear receptor
-
Heery, D. M., E. Kalkhoven, S. Hoare, and M. G. Parker. 1997. A signature motif in transcriptional co-activators mediates binding to nuclear receptor. Nature 387:733-736.
-
(1997)
Nature
, vol.387
, pp. 733-736
-
-
Heery, D.M.1
Kalkhoven, E.2
Hoare, S.3
Parker, M.G.4
-
18
-
-
0030950531
-
AF-2 activity and recruitment of steroid receptor coactivator 1 to the estrogen receptor depend on a lysine residue conserved in nuclear receptors
-
Henttu, P. M. A., E. Kalkhoven, and M. G. Parker. 1997. AF-2 activity and recruitment of steroid receptor coactivator 1 to the estrogen receptor depend on a lysine residue conserved in nuclear receptors. Mol. Cell. Biol. 17: 1832-1839.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1832-1839
-
-
Henttu, P.M.A.1
Kalkhoven, E.2
Parker, M.G.3
-
19
-
-
0032554825
-
Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9 cell differentiation
-
Kawasaki, H., R. Eckner, T.-P. Yao, K. Taira, R. Chiu, D. M. Livingston, and K. K. Yokoyama. 1998. Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9 cell differentiation. Nature 393:284-289.
-
(1998)
Nature
, vol.393
, pp. 284-289
-
-
Kawasaki, H.1
Eckner, R.2
Yao, T.-P.3
Taira, K.4
Chiu, R.5
Livingston, D.M.6
Yokoyama, K.K.7
-
20
-
-
0031892525
-
Conformational adaptation of agonists to the human nuclear receptor RAR gamma
-
Klaholz, B. P., J. P. Renaud, A. Mitschler, C. Zusi, P. Chambon, H. Gronemeyer, and D. Moras. 1998. Conformational adaptation of agonists to the human nuclear receptor RAR gamma. Nat. Struct. Biol. 5:199-202.
-
(1998)
Nat. Struct. Biol.
, vol.5
, pp. 199-202
-
-
Klaholz, B.P.1
Renaud, J.P.2
Mitschler, A.3
Zusi, C.4
Chambon, P.5
Gronemeyer, H.6
Moras, D.7
-
21
-
-
0029811878
-
Identification and functional separation of retinoic acid receptor neutral antagonists and inverse agonists
-
Klein, E, S., M. E. Pino, A. T. Johnson, P. J. Davies, S. Nagpal, S. M. Thacher, G. Krasinski, and R. A. Chandraratna. 1996. Identification and functional separation of retinoic acid receptor neutral antagonists and inverse agonists. J. Biol. Chem. 271:22692-22696.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22692-22696
-
-
Klein, E.1
Pino, M.E.2
Johnson, A.T.3
Davies, P.J.4
Nagpal, S.5
Thacher, S.M.6
Krasinski, G.7
Chandraratna, R.A.8
-
22
-
-
0028122988
-
Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding
-
Kurokawa, R., J. Direnzo, M. Boehm, J. Sugarman, B. Gloss, M. G. Rosenfeld, R. A. Heyman, and C. K. Glass. 1994. Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding. Nature 371:528-531.
-
(1994)
Nature
, vol.371
, pp. 528-531
-
-
Kurokawa, R.1
Direnzo, J.2
Boehm, M.3
Sugarman, J.4
Gloss, B.5
Rosenfeld, M.G.6
Heyman, R.A.7
Glass, C.K.8
-
23
-
-
0029154931
-
Polarity-specific activities of retinoic acid receptors determined by a co-repressor
-
Kurokawa, R., M. Soderstrom, A. Horlein, S. Halachmi, M. Brown, M. G. Rosenfeld, and C. K. Glass. 1995. Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature 377:451-454.
-
(1995)
Nature
, vol.377
, pp. 451-454
-
-
Kurokawa, R.1
Soderstrom, M.2
Horlein, A.3
Halachmi, S.4
Brown, M.5
Rosenfeld, M.G.6
Glass, C.K.7
-
24
-
-
0029837242
-
Analysis of the ligand-binding domain of human retinoic acid receptor alpha by site-directed mutagenesis
-
Lamour, F. P., P. Lardelli, and C. M. Apfel. 1996. Analysis of the ligand-binding domain of human retinoic acid receptor alpha by site-directed mutagenesis. Mol. Cell. Biol. 16:5386-5392.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5386-5392
-
-
Lamour, F.P.1
Lardelli, P.2
Apfel, C.M.3
-
25
-
-
0029954388
-
The receptor-DNA complex determines the retinoid response: A mechanism for the diversification of the ligand signal
-
La Vista-Picard, N., P. D. Hobbs, M. Pfahl, and M. I. Dawson. 1996. The receptor-DNA complex determines the retinoid response: a mechanism for the diversification of the ligand signal. Mol. Cell. Biol. 16:4137-4146.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4137-4146
-
-
La Vista-Picard, N.1
Hobbs, P.D.2
Pfahl, M.3
Dawson, M.I.4
-
26
-
-
0031741654
-
Cloning and characterization of mouse RIP 140, a corepressor for nuclear orphan receptor TR2
-
Lee, C. H., C. Chinpaisal, and L. N. Wei. 1998. Cloning and characterization of mouse RIP 140, a corepressor for nuclear orphan receptor TR2. Mol. Cell. Biol. 18:6745-6755.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6745-6755
-
-
Lee, C.H.1
Chinpaisal, C.2
Wei, L.N.3
-
27
-
-
0032581032
-
H11-H12 loop retinoic acid receptor mutants exhibit distinct trans-activating and trans-repressing activities in the presence of natural or synthetic retinoids
-
Lefebvre, B., A. Mouchon, P. Formstecher, and P. Lefebvre. 1998. H11-H12 loop retinoic acid receptor mutants exhibit distinct trans-activating and trans-repressing activities in the presence of natural or synthetic retinoids. Biochemistry 37:9240-9249.
-
(1998)
Biochemistry
, vol.37
, pp. 9240-9249
-
-
Lefebvre, B.1
Mouchon, A.2
Formstecher, P.3
Lefebvre, P.4
-
28
-
-
0032580291
-
Distinct modes of interaction of the retinoic acid receptor alpha with natural and synthetic retinoids
-
Lefebvre, B., A. Mouchon, P. Formstecher, and P. Lefebvre. 1998. Distinct modes of interaction of the retinoic acid receptor alpha with natural and synthetic retinoids. Mol. Cell. Endocrinol. 139:161-169.
-
(1998)
Mol. Cell. Endocrinol.
, vol.139
, pp. 161-169
-
-
Lefebvre, B.1
Mouchon, A.2
Formstecher, P.3
Lefebvre, P.4
-
29
-
-
0028988573
-
Structural determinants of the ligand-binding site of the human retinoic acid receptor alpha
-
Lefebvre, B., C. Rachez, P. Formstecher, and P. Lefebvre. 1995. Structural determinants of the ligand-binding site of the human retinoic acid receptor alpha. Biochemistry 34:5477-5485.
-
(1995)
Biochemistry
, vol.34
, pp. 5477-5485
-
-
Lefebvre, B.1
Rachez, C.2
Formstecher, P.3
Lefebvre, P.4
-
30
-
-
85038176457
-
-
Unpublished data
-
Lefebvre, P., et al. Unpublished data.
-
-
-
Lefebvre, P.1
-
31
-
-
0028908514
-
Protein phosphatases 1 and 2A regulate the transcriptional and DNA binding activities of retinoic acid receptors
-
Lefebvre, P., M. P. Gaub, A. Tahayato, C. Rochette-Egly, and P. Formstecher. 1995. Protein phosphatases 1 and 2A regulate the transcriptional and DNA binding activities of retinoic acid receptors. J. Biol. Chem. 270: 10806-10816.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 10806-10816
-
-
Lefebvre, P.1
Gaub, M.P.2
Tahayato, A.3
Rochette-Egly, C.4
Formstecher, P.5
-
32
-
-
0032524348
-
Binding of retinoic acid receptor heterodimers to DNA - A role for histones NH2 termini
-
Lefebvre, P., A. Mouchon, B. Lefebvre, and P. Formstecher. 1998. Binding of retinoic acid receptor heterodimers to DNA - a role for histones NH2 termini. J. Biol. Chem. 273:12288-12295.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12288-12295
-
-
Lefebvre, P.1
Mouchon, A.2
Lefebvre, B.3
Formstecher, P.4
-
33
-
-
0032580207
-
Allosteric effects of DNA on transcriptional regulators
-
Lefstin, J. A., and K. R. Yamamoto. 1998. Allosteric effects of DNA on transcriptional regulators. Nature 392:885-888.
-
(1998)
Nature
, vol.392
, pp. 885-888
-
-
Lefstin, J.A.1
Yamamoto, K.R.2
-
34
-
-
0027754125
-
Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor
-
Leng, X., S. Y. Tsai, B. W. O'Malley, and M.-J. Tsai. 1993. Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor. J. Steroid Biochem. Mol. Biol. 46:643-661.
-
(1993)
J. Steroid Biochem. Mol. Biol.
, vol.46
, pp. 643-661
-
-
Leng, X.1
Tsai, S.Y.2
O'Malley, B.W.3
Tsai, M.-J.4
-
35
-
-
0032489555
-
The receptor-associated coactivator 3 activates transcription through CREB-binding protein recruitment and autoregulation
-
Li, H., and J. D. Chen. 1998. The receptor-associated coactivator 3 activates transcription through CREB-binding protein recruitment and autoregulation. J. Biol. Chem. 273:5948-5954.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5948-5954
-
-
Li, H.1
Chen, J.D.2
-
36
-
-
0028079763
-
Vitamin A, differentiation and cancer
-
Love, J. M., and L. J. Gudas. 1994. Vitamin A, differentiation and cancer. Curr. Opin. Cell Biol. 6:825-831.
-
(1994)
Curr. Opin. Cell Biol.
, vol.6
, pp. 825-831
-
-
Love, J.M.1
Gudas, L.J.2
-
37
-
-
0032213938
-
Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation
-
MacInerney, E. M., D. W. Rose, S. E. Flynn, S. Westin, T. M. Mullen, A. Krones, J. Inostroza, J. Torchia, R. T. Nolte, N. Assamunt, M. V. Milburn, C. K. Glass, and M. G. Rosenfeld. 1998. Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation. Genes Dev. 12:3357-3368.
-
(1998)
Genes Dev.
, vol.12
, pp. 3357-3368
-
-
MacInerney, E.M.1
Rose, D.W.2
Flynn, S.E.3
Westin, S.4
Mullen, T.M.5
Krones, A.6
Inostroza, J.7
Torchia, J.8
Nolte, R.T.9
Assamunt, N.10
Milburn, M.V.11
Glass, C.K.12
Rosenfeld, M.G.13
-
38
-
-
0027381438
-
The patterns of binding of RAR, RXR and TR homodimers and heterodimers to direct repeats are dictated by the binding specificities of the DNA binding domains
-
Mader, S., J. Y. Chen, Z. P. Chen, J. White, P. Chambon, and H. Gronemeyer. 1993. The patterns of binding of RAR, RXR and TR homodimers and heterodimers to direct repeats are dictated by the binding specificities of the DNA binding domains. EMBO J. 12:5029-5041.
-
(1993)
EMBO J.
, vol.12
, pp. 5029-5041
-
-
Mader, S.1
Chen, J.Y.2
Chen, Z.P.3
White, J.4
Chambon, P.5
Gronemeyer, H.6
-
39
-
-
0026547997
-
Selective synthetic ligands for human nuclear retinoic acid receptors
-
Martin, B., J. M. Bernardon, M. T. Cavey, B. Bernard, I. Carlavan, B. Charpentier, W. R. Pilgrim, B. Shroot, and U. Reichert. 1992. Selective synthetic ligands for human nuclear retinoic acid receptors. Skin Pharmacol. 5:57-65.
-
(1992)
Skin Pharmacol.
, vol.5
, pp. 57-65
-
-
Martin, B.1
Bernardon, J.M.2
Cavey, M.T.3
Bernard, B.4
Carlavan, I.5
Charpentier, B.6
Pilgrim, W.R.7
Shroot, B.8
Reichert, U.9
-
40
-
-
0029007929
-
The roles of retinoids in vertebrate development
-
Means, A. L., and L. J. Gudas. 1995. The roles of retinoids in vertebrate development. Annu. Rev. Biochem. 64:201-233.
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 201-233
-
-
Means, A.L.1
Gudas, L.J.2
-
41
-
-
0031038518
-
Retinoid X receptor (RXR) within the RXR-retinoic acid receptor heterodimer binds its ligand and enhances retinoid-dependent gene expression
-
Minucci, S., M. Leid, R. Toyama, J. P. Saintjeannet, V. J. Peterson, V. Horn, J. E. Ishmael, N. Bhattacharyya, A. Dey, I. B. Dawid, and K. Ozato. 1997. Retinoid X receptor (RXR) within the RXR-retinoic acid receptor heterodimer binds its ligand and enhances retinoid-dependent gene expression. Mol. Cell. Biol. 17:644-655.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 644-655
-
-
Minucci, S.1
Leid, M.2
Toyama, R.3
Saintjeannet, J.P.4
Peterson, V.J.5
Horn, V.6
Ishmael, J.E.7
Bhattacharyya, N.8
Dey, A.9
Dawid, I.B.10
Ozato, K.11
-
42
-
-
0031833450
-
The nuclear receptor ligand-binding domain: Structure and function
-
Moras, D., and H. Gronemeyer. 1998. The nuclear receptor ligand-binding domain: structure and function. Curr. Opin. Cell Biol. 10:384-391.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 384-391
-
-
Moras, D.1
Gronemeyer, H.2
-
43
-
-
0027154780
-
RARs and RXRs - Evidence for 2 autonomous transactivation functions (AF-1 and AF-2) and heterodimerization invivo
-
Nagpal, S., S. Friant, H. Nakshatri, and P. Chambon. 1993. RARs and RXRs - evidence for 2 autonomous transactivation functions (AF-1 and AF-2) and heterodimerization invivo. EMBO J. 12:2349-2360.
-
(1993)
EMBO J.
, vol.12
, pp. 2349-2360
-
-
Nagpal, S.1
Friant, S.2
Nakshatri, H.3
Chambon, P.4
-
44
-
-
0028950218
-
Separation of transactivation and AP1 antagonism functions of retinoic acid receptor alpha
-
Nagpal, S., J. Athanikar, and R. A. S. Chandraratna. 1995. Separation of transactivation and AP1 antagonism functions of retinoic acid receptor alpha. J. Biol. Chem. 270:923-927.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 923-927
-
-
Nagpal, S.1
Athanikar, J.2
Chandraratna, R.A.S.3
-
45
-
-
0032505096
-
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor y
-
Nolte, R. T., G. B. Wisely, S. Westin, J. E. Cobb, M. H. Lambert, R. Kurokawa, M. G. Rosenfeld, T. M. Willson, C. K. Glass, and M. V. Milburn. 1998. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor y. Nature 395:137-143.
-
(1998)
Nature
, vol.395
, pp. 137-143
-
-
Nolte, R.T.1
Wisely, G.B.2
Westin, S.3
Cobb, J.E.4
Lambert, M.H.5
Kurokawa, R.6
Rosenfeld, M.G.7
Willson, T.M.8
Glass, C.K.9
Milburn, M.V.10
-
46
-
-
0028846193
-
Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
-
Oňate, S. A., S. Y. Tsai, M. J. Tsai, and B. W. O'Malley. 1995. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270:1354-1357.
-
(1995)
Science
, vol.270
, pp. 1354-1357
-
-
Oňate, S.A.1
Tsai, S.Y.2
Tsai, M.J.3
O'Malley, B.W.4
-
47
-
-
0032488839
-
Serine 232 and methionine 272 define the ligand binding pocket in retinoic acid receptor subtypes
-
Ostrowski, J., T. Roalsvig, L. Hammer, A. Marinier, J. E. Starrett, K. L. Yuo, and P. R. Reczek. 1998. Serine 232 and methionine 272 define the ligand binding pocket in retinoic acid receptor subtypes. J. Biol. Chem. 273:3490-3495.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3490-3495
-
-
Ostrowski, J.1
Roalsvig, T.2
Hammer, L.3
Marinier, A.4
Starrett, J.E.5
Yuo, K.L.6
Reczek, P.R.7
-
48
-
-
0029994355
-
Identification of amino acids critical for the DNA binding and dimerization properties of the human retinoic acid receptor alpha. Importance of lysine 360, lysine 365, and valine 361
-
Rachez, C., P. Sautiere, P. Formstecher, and P. Lefebvre. 1996. Identification of amino acids critical for the DNA binding and dimerization properties of the human retinoic acid receptor alpha. Importance of lysine 360, lysine 365, and valine 361. J. Biol. Chem. 271:17996-8006.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17996-18006
-
-
Rachez, C.1
Sautiere, P.2
Formstecher, P.3
Lefebvre, P.4
-
49
-
-
0029643780
-
Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid
-
Renaud, J. P., N. Rochel, M. Ruff, V. Vivat, P. Chambon, H. Gronemeyer, and D. Moras. 1995. Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid. Nature 378:681-689.
-
(1995)
Nature
, vol.378
, pp. 681-689
-
-
Renaud, J.P.1
Rochel, N.2
Ruff, M.3
Vivat, V.4
Chambon, P.5
Gronemeyer, H.6
Moras, D.7
-
50
-
-
0028811341
-
Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specific ligand
-
Roy, D. Y., R. Taneja, and P. Chambon. 1995. Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specific ligand. Mol. Cell. Biol. 15:6481-6487.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6481-6487
-
-
Roy, D.Y.1
Taneja, R.2
Chambon, P.3
-
51
-
-
0030994388
-
The promoter context is a decisive factor in establishing selective responsiveness to nuclear class II receptors
-
Sanguedolce, M. V., B. P. Leblanc, J. L. Betz, and H. G. Stunnenberg. 1997. The promoter context is a decisive factor in establishing selective responsiveness to nuclear class II receptors. EMBO J. 16:2861-2873.
-
(1997)
EMBO J.
, vol.16
, pp. 2861-2873
-
-
Sanguedolce, M.V.1
Leblanc, B.P.2
Betz, J.L.3
Stunnenberg, H.G.4
-
52
-
-
0030946993
-
Differential role of homologous positively charged amino acid residues for ligand binding in retinoic acid receptor alpha compared with retinoic acid receptor beta
-
Scafonas, A., C. L. Wolfgang, J. L. Gabriel, K. J. Soprano, and D. R. Soprano. 1997. Differential role of homologous positively charged amino acid residues for ligand binding in retinoic acid receptor alpha compared with retinoic acid receptor beta. J. Biol. Chem. 272:11244-11249.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11244-11249
-
-
Scafonas, A.1
Wolfgang, C.L.2
Gabriel, J.L.3
Soprano, K.J.4
Soprano, D.R.5
-
53
-
-
0031043055
-
The phantom ligand effect: Allosteric control of transcription by the retinoic X receptor
-
Schulman, I. G., C. Li, J. W. Schwabe, and R. M. Evans. 1997. The phantom ligand effect: allosteric control of transcription by the retinoic X receptor. Genes Dev. 11:299-308.
-
(1997)
Genes Dev.
, vol.11
, pp. 299-308
-
-
Schulman, I.G.1
Li, C.2
Schwabe, J.W.3
Evans, R.M.4
-
54
-
-
0029017712
-
Pharmacology of retinoids in the skin: In vitro and in vivo assays
-
Shroot, B., and S. Michel. 1995. Pharmacology of retinoids in the skin: In vitro and in vivo assays. Eur. J. Med. Chem. 30:S487-S503.
-
(1995)
Eur. J. Med. Chem.
, vol.30
-
-
Shroot, B.1
Michel, S.2
-
55
-
-
0031005656
-
Pharmacology and chemistry of adapalene
-
Shroot, B., and S. Michel. 1997. Pharmacology and chemistry of adapalene. J. Am. Acad. Dermatol. 36:S95-S103.
-
(1997)
J. Am. Acad. Dermatol.
, vol.36
-
-
Shroot, B.1
Michel, S.2
-
56
-
-
0027173821
-
Structural evolution of retinoids
-
Shudo, K., and H. Kagechika. 1993. Structural evolution of retinoids. Adv. Drug Res. 24:81-119.
-
(1993)
Adv. Drug Res.
, vol.24
, pp. 81-119
-
-
Shudo, K.1
Kagechika, H.2
-
57
-
-
0028348240
-
Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptor-alpha
-
Tate, B. F., G. Allenby, R. Janocha, S. Kazmer, J. Speck, L. J. Sturzenbecker, P. Abarzua, A. A. Levin, and J. F. Grippo. 1994. Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptor-alpha. Mol. Cell. Biol. 14:2323-2330.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2323-2330
-
-
Tate, B.F.1
Allenby, G.2
Janocha, R.3
Kazmer, S.4
Speck, J.5
Sturzenbecker, L.J.6
Abarzua, P.7
Levin, A.A.8
Grippo, J.F.9
-
58
-
-
0029050907
-
Mutagenesis of the ligand binding domain of the human retinoic acid receptor alpha identifies critical residues for 9-cis-retinoic acid binding
-
Tate, B. F., and J. F. Grippo. 1995. Mutagenesis of the ligand binding domain of the human retinoic acid receptor alpha identifies critical residues for 9-cis-retinoic acid binding. J. Biol. Chem. 270:20258-20263.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 20258-20263
-
-
Tate, B.F.1
Grippo, J.F.2
-
59
-
-
0031835267
-
Co-activators and co-repressors in the integration of transcriptional responses
-
Torchia, J., C. K. Glass, and M. G. Rosenfeld. 1998. Co-activators and co-repressors in the integration of transcriptional responses. Curr. Opin. Cell Biol. 10:373-383.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 373-383
-
-
Torchia, J.1
Glass, C.K.2
Rosenfeld, M.G.3
-
60
-
-
0029643769
-
A structural role for hormone in the thyroid hormone receptor
-
Wagner, R. L., J. W. Apriletti, M. E. Mcgrath, B. L. West, J. D. Baxter, and R. J. Fletterick. 1995. A structural role for hormone in the thyroid hormone receptor. Nature 378:690-697.
-
(1995)
Nature
, vol.378
, pp. 690-697
-
-
Wagner, R.L.1
Apriletti, J.W.2
Mcgrath, M.E.3
West, B.L.4
Baxter, J.D.5
Fletterick, R.J.6
-
61
-
-
0032505066
-
Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators
-
Westin, S., R. Kurokawa, R. T. Nolte, G. B. Wisely, E. M. McInerney, D. W. Rose, M. V. Milburn, M. G. Rosenfeld, and C. K. Glass. 1998. Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators. Nature 395:199-202.
-
(1998)
Nature
, vol.395
, pp. 199-202
-
-
Westin, S.1
Kurokawa, R.2
Nolte, R.T.3
Wisely, G.B.4
McInerney, E.M.5
Rose, D.W.6
Milburn, M.V.7
Rosenfeld, M.G.8
Glass, C.K.9
-
62
-
-
0032575057
-
Atomic structure of progesterone complexed with its receptor
-
Williams, S. P., and P. B. Sigler. 1998. Atomic structure of progesterone complexed with its receptor. Nature 393:392-396.
-
(1998)
Nature
, vol.393
, pp. 392-396
-
-
Williams, S.P.1
Sigler, P.B.2
-
63
-
-
0030056997
-
A canonical structure for the ligand-binding domain of nuclear receptors
-
Wurtz, J. M., W. Bourguet, J. P. Renaud, V. Vivat, P. Chambon, D. Moras, and H. Gronemeyer. 1996. A canonical structure for the ligand-binding domain of nuclear receptors. Nat. Struct. Biol. 3:87-94.
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 87-94
-
-
Wurtz, J.M.1
Bourguet, W.2
Renaud, J.P.3
Vivat, V.4
Chambon, P.5
Moras, D.6
Gronemeyer, H.7
-
64
-
-
0028796740
-
Endogenous retinoic acid receptor (RAR)-rctinoid X receptor (RXR) heterodimers are the major functional forms regulating retinoid-responsive elements in adult human keratinocytes. Binding of ligands to RAR only is sufficient for RAR-RXR heterodimers to confer ligand-dependent activation of hRAR beta 2/RARE (DRS)
-
Xiao, J. H., B. Durand, P. Chambon, and J. J. Voorhees. 1995. Endogenous retinoic acid receptor (RAR)-rctinoid X receptor (RXR) heterodimers are the major functional forms regulating retinoid-responsive elements in adult human keratinocytes. Binding of ligands to RAR only is sufficient for RAR-RXR heterodimers to confer ligand-dependent activation of hRAR beta 2/RARE (DRS). J. Biol. Chem. 270:3001-3011.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3001-3011
-
-
Xiao, J.H.1
Durand, B.2
Chambon, P.3
Voorhees, J.J.4
-
65
-
-
0030796096
-
Activation of the orphan receptor RIP14 by retinoids
-
Zavacki, A. M., J. M. Lehmann, W. Seol. T. M. Willson, S. A. Kliewer, and D. D. Moore. 1997. Activation of the orphan receptor RIP14 by retinoids. Proc. Natl. Acad. Sci. USA 94:7909-7914.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7909-7914
-
-
Zavacki, A.M.1
Lehmann, J.M.2
Seol, W.3
Willson, T.M.4
Kliewer, S.A.5
Moore, D.D.6
-
66
-
-
0028335132
-
Mutations that alter ligand-induced switches and dimerization activities in the retinoid X receptor
-
Zhang, X. K., G. Salbert, M. O. Lee, and M. Pfahl. 1994. Mutations that alter ligand-induced switches and dimerization activities in the retinoid X receptor. Mol. Cell. Biol. 14:4311-4323.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 4311-4323
-
-
Zhang, X.K.1
Salbert, G.2
Lee, M.O.3
Pfahl, M.4
|