Transduction of pancreatic islets with pseudotyped adeno-associated virus: Effect of viral capsid and genome conversion

Transplantation

Volumn 80, Issue 5, 2005, Pages 683-690

  Zhang, Nan ^a   Clément, Nathalie ^a   Chen, Dongmei ^a   Fu, Shuang ^a   Zhang, Haojiang ^a   Rebollo, Patricia ^a   Linden, R Michael ^a   Bromberg, Jonathan S ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Adeno associated virus; Capsid; Double stranded; Pancreatic islet

Indexed keywords

DOUBLE STRANDED DNA; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ARTICLE; DIABETES MELLITUS; GENE CONVERSION; GENE THERAPY; GENETIC COMPLEMENTATION; GENOME ANALYSIS; GRAFT SURVIVAL; HUMAN; HUMAN CELL; PANCREAS ISLET; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; REPORTER GENE; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE; VIRUS CAPSID; VIRUS GENOME; VIRUS TYPING;

ADENOVIRIDAE; ANIMALS; CAPSID; DIABETES MELLITUS, EXPERIMENTAL; DNA; DNA, SINGLE-STRANDED; GENE THERAPY; GENES, REPORTER; GENOME, VIRAL; GREEN FLUORESCENT PROTEINS; HUMANS; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED BALB C; MICE, SCID; TRANSDUCTION, GENETIC; TRANSGENES; TRANSPLANTATION, HETEROLOGOUS;

EID: 25444521541     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000173381.97556.0d     Document Type: Article

References (40)

1. Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000; 343: 230-238.
2. Boker A, Rothenberg L, Hernandez C, et al. Human islet transplantation: update. World J Surg 2001; 25: 481-486.
3. Ryan EA, Lakey JR, Rajotte RV, et al. Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes 2001; 50: 710-719.
4. Ryan EA, Lakey JR, Paty BW, et al. Successful islet transplantation: continued insulin reserve provides long-term glycemic control. Diabetes 2002; 51: 2148-2157.
5. Cattan P, Berney T, Schena S, et al. Early assessment of apoptosis in isolated islets of Langerhans. Transplantation 2001; 71: 857-7862.
6. Bosco D, Meda P, Halban PA, Rouiller DG. Importance of cell-matrix interactions in rat islet beta-cell secretion in vitro: role of α6β1 integrin. Diabetes 2000; 49: 233-243.
7. Wang RN, Rosenberg L. Maintenance of beta-cell function and survival following islet isolation requires re-establishment of the islet-matrix relationship. J Endocrinol 1999; 163: 181-190.
8. Zhang N, Richter Anja, Suriawinata J, et al. Elevated VEGF production in islets improves islet graft vascularization. Diabetes 2004; 53: 963-970.
9. Zhang N, Schroppel B, Chen D, et al. Adenovirus transplantation induces expression of multiple chemokines and chemokine receptors in murine β cells and pancreatic islet. Am J Transplant 2003; 3: 1230-1241.
10. Flotte T, Agarwal A, Wang J, et al. Efficient ex vivo transduction of pancreatic islet cells with recombinant adeno-associated virus vectors. Diabetes 2001; 50: 515-520.
11. Loiler SA, Conlon TJ, Song S, et al. Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver. Gene Ther 2003; 10: 1551-1558.
12. Grimm D, Kleinschmidt JA. Progress in adeno-associated virus type 2 vector production: promises and prospects for clinical use. Hum Gene Ther 1999; 10: 2445-2450.
13. Conrad CK, Allen SS, Afione SA, et al. Safety of single-dose administration of an adeno-associated virus (AAV)-CFTR vector in the primate lung. Gene Ther 1996; 3: 658-668.
14. Hernandez YJ, Wang J, Kearns WG. Latent adeno-associated virus infection elicits humoral but not cell-mediated immune responses in a nonhuman primate model. J Virol 1999; 73: 8549-8558.
15. Erles K, Sebokova P, Schlehofer JR. Update on the prevalence of serum antibodies (IgG and IgM) to adeno-associated virus (AAV). J Med Virol 1999; 59: 406-411.
16. Wang Z, Ma HI, Li J, et al. Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo. Gene Ther 2003; 10: 2105-2111.
17. Xiao W, Warrington KH, Hearing P, et al. Adenovirus-facilitated nuclear translocation of adeno-associated virus type 2. J Virol 2002; 76: 11505-11517.
18. Ricordi C, Lacy PE, Finke EH, et al. Automated method for isolation of human pancreatic islets. Diabetes 1988; 37: 413-420.
19. Ricordi C, Gray DW, Hering BJ, et al. Islet isolation assessment in man and large animals. Acta Diabetol Lat 1990; 27: 185-195.
20. Zolotukhin S, Potter M, Hauswirth WW, Guy J, Muzyczka N. A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells. J Virol 1996; 70: 4646-4654.
21. Grimm D, Kern A, Rittner K, Kleinschmidt JA. Novel tools for production and purification of recombinant adenoassociated virus vectors. Hum Gene Ther 1998; 9: 2745-2760.
22. Zolotukhin S, Potter M, Zolotukhin I, et al. Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors. Methods 2002; 28: 158-167.
23. Afioneb SA, Wang J, Walshb S, et al. Delayed expression of adeno-associated virus vector DNA. Intervirology 1999; 42: 213-222.
24. Rabinowitz JE, Rolling F, Li C, et al. Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity. J Virol 2002; 76: 791-801.
25. Halbert CL, Rutledge EA, Allen JM, et al. Repeat transduction in the mouse lung by using adeno-associated virus vectors with different serotypes. J Virol 2000; 74: 1524-1532.
26. Chao HJ, Liu Y, Samulski RJ, et al. Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors. Mol Ther 2000; 2: 619-623.
27. Davidson BL, Stein CS, Heth JA, et al. From the cover: Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system. PNAS 2000; 97: 3428-3432.
28. Hildinger M, Auricchio A, Gao G, et al. Hybrid vectors based on adeno-associated virus serotypes 2 and 5 for muscle-directed gene transfer. J Virol 2001; 75: 6199-6203.
29. Chiorini JA, Kim F, Yang L, Kotin RM. Cloning and characterization of adeno-associated virus type 5. J Virol 1999; 73: 1309-1319.
30. Rutledge EA, Halbert CL, Russell DW. Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2. J Virol 1998; 72: 309-319.
31. Qing K, Mah C, Hansen J, et al. Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2. Nat Med 1999; 5: 71-77.
32. Summerford C, Bartlett JS, Samtfiski RJ. AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection. Nat Med 1999; 5: 78-82.
33. Summerford C, Samulski RJ. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. J Virol 1998; 72: 1438-1445.
34. Walters RW, Yi SMP, Keshavjee S, et al. Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer. J Biol Chem 2001; 276: 20610-20616.
35. Pasquale GD, Davidson BL, Stein CS, et al. Identification of PDGFR as a receptor for AAV-5 transduction. Nat Med 2003; 9: 1306-1312.
36. Halbert CL, Allen JM, Miller AD. Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors. J Virol 2001; 75: 6615-6624.
37. Zabner J, Seiler M, Walters R, et al. Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer. J Virol 2000; 74: 3852-3858.
38. Gao G, Alvira MR, Wang L, et al. Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy. PNAS 2002; 99: 11854-11859.
39. Gao G, Vandenberghe LH, Alvira MR, et al. Glades of Adeno-associated viruses are widely disseminated in human tissues. J Virol 2004; 78: 6381-6388.
40. Ferrari FK, Samulski T, Shenk T, Samulski RJ. Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors. J Virol 1996; 70: 3227-3234.