Safety of single-dose administration of an adeno-associated virus (AAV)-CFTR vector in the primate lung

Gene Therapy

Volumn 3, Issue 8, 1996, Pages 658-668

  Conrad, C K ^a   Allen, S S ^a   Afione, S A ^a   Reynolds, T C ^b   Beck, S E ^a   Fee Maki, M ^b   Barrazza Ortiz, X ^a   Adams, R ^a   Askin, F B ^a   Carter, B J ^b   Guggino, W B ^a   Flotte, T R ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Genetic Systems Inc   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

AAV; Cystic fibrosis; Gene expression; Gene therapy; Parvovirus; Toxicity

Indexed keywords

CYTOKINE; RIBONUCLEASE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL GAS; ARTICLE; CELL COUNT; CONTROLLED STUDY; CYSTIC FIBROSIS; EXPRESSION VECTOR; FEMALE; FIBEROPTIC BRONCHOSCOPY; GENE THERAPY; INFLAMMATION; LUNG LOBE; LUNG MECHANICS; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RHESUS MONKEY; SAFETY; THORAX RADIOGRAPHY;

ANIMALS; BRONCHOALVEOLAR LAVAGE; BRONCHOSCOPY; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DEPENDOVIRUS; FEMALE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; LUNG; MACACA MULATTA; MALE; POLYMERASE CHAIN REACTION; RESPIRATORY FUNCTION TESTS; RNA, VIRAL;

ADENO-ASSOCIATED VIRUS; ANIMALIA; MACACA MULATTA; ORYCTOLAGUS CUNICULUS; PARVOVIRUS; PRIMATES;

EID: 0029741735     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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