TGF-β1 stimulates monocyte chemoattractant protein-1 expression in mesangial cells through a phosphodiesterase isoenzyme 4-dependent process

American Journal of Physiology - Cell Physiology

Volumn 289, Issue 4 58-4, 2005, Pages

  Cheng, Jingfei ^a   Encarnacion, Montserrat M Diaz ^a   Warner, Gina M ^a   Gray, Catherine E ^a   Nath, Karl A ^a   Grande, Joseph P ^a  

^a Mayo Clinic   (United States)

Author keywords

cAMP; Inflammation; Mitogen activated protein kinase; Reactive oxygen species

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; REACTIVE OXYGEN METABOLITE; ROLIPRAM; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; 3',5' CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; TGFB1 PROTEIN, RAT; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; INFLAMMATION; KIDNEY DISEASE; KIDNEY INJURY; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL LINE; CYTOLOGY; DRUG ANTAGONISM; GENE EXPRESSION; MESANGIUM; METABOLISM; PHYSIOLOGY; RAT;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; CELL LINE; CHEMOKINE CCL2; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; GLOMERULAR MESANGIUM; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 25444495661     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00153.2005     Document Type: Article

References (64)

1. Baeuerle PA and Henkel T. Function and activation of NF-κB in the immune system. Annu Rev Immunol 12: 141-179, 1994.
2. Beavo J. Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. Physiol Rev 75: 725-748, 1995.
3. Border WA and Noble NA. TGF-β in kidney fibrosis: a target for gene therapy. Kidney Int 51: 1388-1396, 1997.
4. 2, and iron are required for TNF-α-induced MCP-1 gene expression in endothelial cells: role of Rac1 and NADPH oxidase. Am J Physiol Heart Circ Physiol 286: H1001-H1007, 2004.
5. Cheng J and Grande JP. Transforming growth factor-β signal transduction and progressive renal disease. Exp Biol Med 227: 943-956, 2002.
6. Cheng J, Thompson MA, Walker HJ, Gray CE, Diaz Encarnacion MM, Warner GM, and Grande JP. Differential regulation of mesangial cell mitogenesis by cAMP phosphodiesterase isozymes 3 and 4. Am J Physiol Renal Physiol 287: F940-F953, 2004.
7. 2+ releasing agent in kidney. J Am Soc Nephrol 12: 54-60, 2001.
8. Chini CCS, Grande JP, Chini EN, and Dousa TP. Compartmentalization of cAMP signaling in mesangial cells by phosphodiesterase isozymes PDE3 and PDE4: regulation of superoxidation and mitogenesis. J Biol Chem 272: 9854-9859, 1997.
9. Church GM and Gilbert W. Genomic sequencing. Proc Natl Acad Sci USA 81: 1991-1995, 1984.
10. Conti M and Jin SL. The molecular biology of cyclic nucleotide phosphodiesterases. Prog Nucleic Acid Res Mol Biol 63: 1-38, 1999.
11. Dousa T. Cyclic-3′,5′-nucleotide phosphodiesterase isozymes in cell biology and pathobiology of the kidney. Kidney Int 55: 29-62, 1999.
12. 1 regulates chemokine and complement production by human proximal tubular epithelial cells. Kidney Int 53: 609-616, 1998.
13. 1 gene expression by monocyte chemoattractant protein-1 via specific receptors. J Biol Chem 271: 17779-17784, 1996.
14. Gharaee-Kermani M, McCullumsmith RE, Charo IF, Kunkel SL, and Phan SH. CC-chemokine receptor 2 required for bleomycin-induced pulmonary fibrosis. Cytokine 24: 266-276, 2003.
15. Giembycz MA. Cilomilast: a second generation phosphodiesterase 4 inhibitor for asthma and chronic obstructive pulmonary disease. Expert Opin Investig Drugs 10: 1361-1379, 2001.
16. Gooch JL, Gorin Y, Zhang BX, and Abboud HE. Involvement of calcineurin in transforming growth factor-β-mediated regulation of extracellular matrix accumulation. J Biol Chem 279: 15561-15570, 2004.
17. 1 and TNFα secreted by mast cells stimulated via the FcεRI activate fibroblasts for high-level production of monocyte chemoattractant protein-1 (MCP-1). Cell Immunol 201: 42-49, 2000.
18. 1 induces collagen IV gene expression in NIH-3T3 cells. Lab Invest 69: 387-395, 1993.
19. Grande JP, Jones ML, Swenson CL, Killen PD, and Warren JS. Lipopolysaccharide induces monocyte chemoattractant protein production by rat mesangial cells. J Lab Clin Med 124: 112-117, 1994.
20. 1, with divergent effects of epidermal growth factor and tumor necrosis factor-α on collagen type I and collagen type IV. J Lab Clin Med 130: 476-486, 1997.
21. Ha H, Yu MR, Choi YJ, Kitamura M, and Lee HB. Role of high glucose-induced nuclear factor-κB activation in monocyte chemoattractant protein-1 expression by mesangial cells. J Am Soc Nephrol 13: 894-902, 2002.
22. mapk in proliferating cultures of epithelial cells. J Biol Chem 270: 7117-7124, 1995.
23. 1 activates MAP kinase in human mesangial cells: a possible role in collagen expression. Kidney Int 56: 1710-1720, 1999.
24. Herrera B, Fernandez M, Roncero C, Ventura JJ, Porras A, Valladares A, Benito M, and Fabregat I. Activation of p38MAPK by TGF-β in fetal rat hepatocytes requires radical oxygen production, but is dispensable for cell death. FEBS Lett 499: 225-229, 2001.
25. 1. J Immunol 159: 2418-2423, 1997.
26. Houslay MD. PDE4 cAMP-specific phosphodiesterases. Prog Nucleic Acid Res Mol Biol 69: 249-315, 2001.
27. Houslay MD, Sullivan M, and Bolger GB. The multienzyme PDE4 cyclic adenosine monophosphate-specific phosphodiesterase family: intracellular targeting, regulation, and selective inhibition by compounds exerting anti-inflammatory and antidepressant actions. Adv Pharmacol 44: 225-342, 1998.
28. 1-induced plasminogen activator inhibitor-1 upregulation in mesangial cells. Biochem Biophys Res Commun 309: 961-966, 2003.
29. Jones ML and Warren JS. Monocyte chemoattractant protein 1 in a rat model of pulmonary granulomatosis. Lab Invest 66: 498-503, 1992.
30. 1- induced IL-6 expression. J Immunol 165: 2190-2197, 2000.
31. 1 actions and the 12/15-lipoxygenase pathway in mesangial cells. J Am Soc Nephrol 16: 352-362, 2005.
32. 1. J Immunol 159: 1404-1411, 1997.
33. Kretzschmar M, Doody J, Timokhina I, and Massague J. A mechanism of repression of TGFβ/Smad signaling by oncogenic Ras. Genes Dev 13: 804-816, 1999.
34. Lakshminarayanan V, Lewallen M, Frangogiannis NG, Evans AJ, Wedin KE, Michael LH, and Entman ML. Reactive oxygen intermediates induce monocyte chemotactic protein-1 in vascular endothelium after brief ischemia. Am J Pathol 159: 1301-1311, 2001.
35. Lin S, Sahai A, Chugh SS, Pan X, Wallner EI, Danesh FR, Lomasney JW, and Kanwar YS. High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and B-Raf signaling pathway. J Biol Chem 277: 41725-41735, 2002.
36. Liu RM, Liu Y, Forman HJ, Olman M, and Tarpey MM. Glutathione regulates transforming growth factor-β-stimulated collagen production in fibroblasts. Am J Physiol Lung Cell Mol Physiol 286: L121-L128, 2004.
37. Lowry O, Rosebrough A, Farr A, and Randall R. Protein measurement with folin phenol reagent. J Biol Chem 193: 265-275, 1951.
38. Manganiello VC, Murata T, Taira M, Belfrage P, and Degerman E. Diversity in cyclic nucleotide phosphodiesterase isoenzyme families. Arch Biochem Biophys 322: 1-13, 1995.
39. Manning CD, Burman M, Christensen SB, Cieslinski LB, Essayan DM, Grous M, Torphy TJ, and Barnette MS. Suppression of human inflammatory cell function by subtype-selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B. Br J Pharmacol 128: 1393-1398, 1999.
40. Matousovic K, Grande JP, Chini CCS, Chini EN, and Dousa TP. Inhibitors of cyclic nucleotide phosphodiesterase isozymes type-III and type-IV suppress mitogenesis of rat mesangial cells. J Clin Invest 96: 401-410, 1995.
41. Mehats C, Jin SL, Wahlstrom J, Law E, Umetsu DT, and Conti M. PDE4D plays a critical role in the control of airway smooth muscle contraction. FASEB J 17: 1831-1841, 2003.
42. 1 and its involvement in induction of egr-1 in mouse osteoblastic cells. J Cell Biol 126: 1079-1088, 1994.
43. Pai R, Ha H, Kirschenbaum MA, and Kamanna VS. Role of tumor necrosis factor-α on mesangial cell MCP-1 expression and monocyte migration: mechanisms mediated by signal transduction. J Am Soc Nephrol 7: 914-923, 1996.
44. Pawluczyk IZA and Harris KPG. Macrophages promote prosclerotic responses in cultured rat mesangial cells: a mechanism for the initiation of glomerulosclerosis. J Am Soc Nephrol 8: 1525-1536, 1997.
45. Rollins BJ, Morrison ED, and Stiles CD. Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties. Proc Natl Acad Sci USA 85: 3738-3742, 1988.
46. Rovin BH, Dickerson JA, Tan LC, and Fassler J. Modulation of IL-1-induced chemokine expression in human mesangial cells through alterations in redox status. Cytokine 9: 178-186, 1997.
47. Sanchez A, Alvarez AM, Benito M, and Fabregat I. Cycloheximide prevents apoptosis, reactive oxygen species production, and glutathione depletion induced by transforming growth factor β in fetal rat hepatocytes in primary culture. Hepatology 26: 935-943, 1997.
48. Sano Y, Harada J, Tashiro S, Gotoh-Mandeville R, Maekawa T, and Ishii S. ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-β signaling. J Biol Chem 274: 8949-8957, 1999.
49. Satriano J and Schlondorff D. Activation and attenuation of transcription factor NF-κB in mouse glomerular mesangial cells in response to tumor necrosis factor α, immunoglobulin G, and adenosine 3′,5′- cyclic monophosphate. J Clin Invest 94: 1629-1636, 1994.
50. Satriano JA, Hora K, Shan Z, Stanley ER, Mori T, and Schlondorff D. Regulation of monocyte chemoattractant protein-1 and macrophage colony-stimulating factor-1 by IFN-γ, tumor necrosis factor-α, IgG aggregates, and cAMP in mouse mesangial cells. J Immunol 150: 1971-1978, 1993.
51. Satriano JA, Shuldiner M, Hora K, Xing Y, Shan Z, and Schlondorff D. Oxygen radicals as second messengers for expression of the monocyte chemoattractant protein, JE/MCP-1, and the monocyte colony-stimulating factor, CSF-1, in response to tumor necrosis factor-α and immunoglobin G: evidence for involvement of reduced nicotinamide adenine dinucleotide phosphate (NADH)-dependent oxidase. J Clin Invest 92: 1564-1571, 1993.
52. Schlondorff D. The role of chemokines in the initiation and progression of renal disease. Kidney Int 47, Suppl: S44-S47, 1995.
53. Schneider A, Panzer U, Zahner G, Wenzel U, Wolf G, Thaiss F, Helmchen U, and Stahl RA. Monocyte chemoattractant protein-1 mediates collagen deposition in experimental glomerulonephritis by transforming growth factor-β. Kidney Int 56: 135-144, 1999.
54. Shibuya H, Yamaguchi K, Shirakabe K, Tonegawa A, Gotoh Y, Ueno N, Irie K, Nishida E, and Matsumoto K. TAB1: an activator of the TAK1 MAPKKK in TGF-β signal transduction. Science 272: 1179-1182, 1996.
55. Slavin J, Unemori E, Hunt TK, and Amento E. Monocyte chemotactic protein-1 (MCP-1) mRNA is down-regulated in human dermal fibroblasts by dexamethasone: differential regulation by TGF-β. Growth Factors 12: 151-157, 1995.
56. 1. FASEB J 14: 1741-1748, 2000.
57. 1. J Biol Chem 270: 30334-30338, 1995.
58. 1 suppresses myeloid Fcγ receptor function by regulating the expression and function of the common γ-subunit. J Immunol 170: 4572-4577, 2003.
59. Trushin SA, Pennington KN, Algeciras-Schimnich A, and Paya CV. Protein kinase C and calcineurin synergize to activate IκB kinase and NF-κB in T lymphocytes. J Biol Chem 274: 22923-22931, 1999.
60. Wang Y, Rangan GK, Goodwin B, Tay YC, and Harris DC. Lipopolysaccharide- induced MCP-1 gene expression in rat tubular epithelial cells is nuclear factor-κB dependent. Kidney Int 57: 2011-2022, 2000.
61. Whitman M. Smads and early developmental signaling by the TGF-β superfamily. Genes Dev 12: 2445-2462, 1998.
62. Yamaguchi K, Shirakabe K, Shibuya H, Irie K, Oishi I, Ueno N, Taniguchi T, Nishida E, and Matsumoto K. Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science 270: 2008-2011, 1995.
63. Yamamoto T, Eckes B, and Krieg T. Effect of interleukin-10 on the gene expression of type I collagen, fibronectin, and decorin in human skin fibroblasts: differential regulation by transforming growth factor-β and monocyte chemoattractant protein-1. Biochem Biophys Res Commun 281: 200-205, 2001.
64. Yue J, Frey R, and Mulder K. Cross-talk between the Smad1 and Ras/MEK signaling pathways for TGFβ. Oncogene 18: 2033-2037, 1999.