Reactive oxygen species mediate TGF-β1-induced plasminogen activator inhibitor-1 upregulation in mesangial cells

Biochemical and Biophysical Research Communications

Volumn 309, Issue 4, 2003, Pages 961-966

  Jiang, Zongpei ^a,c   Seo, Ji Yeon ^b   Ha, Hunjoo ^a   Lee, Eun Ah ^a   Kim, Yu Seun ^b   Han, Dong Cheol ^a   Uh, Soo Tack ^a   Park, Choon Sik ^a   Lee, Hi Bahl ^a  

^a Soonchunhyang University   (South Korea)

^b Yonsei University   (South Korea)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Extracellular matrix; Mesangial expansion; Oxidative stress; Plasmin; Plasminogen activator inhibitor 1; Reactive oxygen species; Renal fibrosis; Signaling pathway; Transforming growth factor 1

Indexed keywords

HYDROGEN PEROXIDE; PLASMIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE CONTROL; GENETIC CODE; GLOMERULUS; HYPOTHESIS; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; UPREGULATION;

EID: 0141453279     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.08.102     Document Type: Article

References (33)

1. Fogo A.B. Mesangial matrix modulation and glomerulosclerosis. Exp. Nephrol. 7:1999;147-159.
2. Peters H., Noble N.A., Border W.A. Transforming growth factor-beta in human glomerular injury. Curr. Opin. Nephrol. Hypertens. 6:1997;389-393.
3. Han D.C., Ziyadeh F.N. Involvement of transforming growth factor-beta and its receptors in the pathogenesis of diabetic nephropathy. Kidney Int. 52(Suppl. 60):1997;S7-S11.
4. Poncelet A.-C., Schnaper H.W. Regulation of human mesangial cells collagen expression by transforming growth factor-. β1 Am. J. Physiol. 275:1998;F458-F466.
5. Suzuki S., Ebihara I., Tomino Y., Koide H. Transcriptional activation of matrix genes by transforming growth factor. β1 in mesangial cells Exp. Nephrol. 1:1993;229-237.
6. McKay N.G., Khong T.F., Haites N.E., Power D.A. The effect of transforming growth factor. β1 on mesangial cells fibronectin synthesis: increased incorporation into the extracellular matrix and reduced pl but no effect on alternative splicing Exp. Mol. Pathol. 59:1993;211-224.
7. Tamooka S., Border W.A., Marshall B.C., Noble N.A. Glomerular matrix accumulation is linked to inhibition of the plasmin protease system. Kidney Int. 42:1992;1462-1469.
8. Baricos W.H., Cortez S.L., Deboisblanc M., Xin S. Transforming growth factor-beta is a potent inhibitor of extracellular matrix degradation by cultured human mesangial cells. J. Am. Soc. Nephrol. 10:1999;790-795.
9. Rerolle J.P., Hertig A., Nguyen G., Sraer J.D., Rondeau E.P. Plasminogen activator inhibitor type 1 is a potential target in renal fibrogenesis. Kidney Int. 58:2000;1841-1850.
10. Baricos W.H., Cortes S.L., El-Dahar S.S., Schnaper H.W. ECM degradation by cultured human mesangial cells is mediated by a PA/plasmin/MMP-2 cascade. Kidney Int. 47:1995;1039-1047.
11. Huang Y., Haraguchi M., Lawrence D.A., Border W.A., Yu L., Noble N.A. A mutant, noninhibitory plasminogen activator inhibitor type 1 decreases matrix accumulation in experimental glomerulonephritis. J. Clin. Invest. 112:2003;379-388.
12. Dennler S., Itoh S., Vivien D., Dijke P.T., Huet S., Gauthier J.M. Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 17:1998;3091-3100.
13. Kutz S.M., Hordines J., McKeown-Longo P.J., Higgins P.J. TGF-. β1 -induced PAI-1 gene expression requires MEK activity and cell-to-substrate adhesion J. Cell Sci. 114:2001;3905-3924.
14. Kutz S.M., Providence K.M., Higgins P.J. Antisense targeting of c-fos transcripts inhibits serum- and TGF-beta 1-stimulated PAI-1 gene expression and directed motility in renal epithelial cells. Cell Motil. Cytoskeleton. 48:2001;163-174.
15. Du X.L., Edelstein D., Rossetti L., Fantus I.G., Goldberg H., Ziyadeh F.N., Wu J., Brownlee M. Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proc. Natl. Acad. Sci. USA. 97:2000;12222-12226.
16. Cheng J.J., Chao Y.J., Wung B.S., Wang D.L. Cyclic strain-induced plasminogen activator inhibitor-1 (PAI-1) release from endothelial cells involves reactive oxygen species. Biochem. Biophys. Res. Commun. 225:1996;100-105.
17. Zhao W., Spitz D.R., Oberley L.W., Robbins M.E. Redox modulation of the pro-fibrogenic mediator plasminogen activator inhibitor-1 following ionizing radiation. Cancer Res. 61:2001;5537-5543.
18. Lafon C., Mathieu C., Guerrin M., Pierre O., Vidal S., Valette A. Transforming growth factor-. β1 -induced apoptosis in human ovarian carcinoma cells: protection by the antioxidant N-acetylcysteine and bcl-2 Cell Growth Differ. 7:1996;1095-1104.
19. Hong Y.H., Peng H.B., Fata V.L., Liao J.K. Hydrogen peroxide-mediated transcriptional induction of macrophage colony-stimulation factor by TGF-. β1 J. Immunol. 159:1997;2418-2423.
20. 2by transforming growth factor-β in Swiss 3T3 fibroblasts. Cell Signal. 11:1999;677-683.
21. 2+ in TGF- β1 -induced IL-6 expression J. Immunol. 165:2000;2190-2197.
22. Chiu C., Maddock D.A., Zhang Q., Souza K.P., Townsend A.R., Wan Y. TGF-β-induced p38 activation is mediated by Rac1-regulated generation of reactive oxygen species in cultured human keratinocytes. Int. J. Mol. Med. 8:2001;251-255.
23. Herrera B., Alvarez A.M., Sanchez A., Fernandez M., Roncero C., Benito M., Fabregat I. Reactive oxygen species mediates the mitochondrial-dependent apoptosis induced by transforming growth factor-β in fetal hepatocyte. FASEB J. 15:2001;741-751.
24. Herrera B., Fernandez M., Roncero C., Ventura J.J., Porras A., Valladares A., Benito M., Fabregat I. Activation of p38MAPK by TGF-beta in fetal rat hepatocytes requires radical oxygen production, but is dispensable for cell death. FEBS Lett. 499:2001;225-229.
25. Oh J.H., Ha H., Yu M.R., Lee H.B. Sequential effects of high glucose on mesangial cell transforming growth factor-. β1 and fibronectin synthesis Kidney Int. 54:1998;1872-1878.
26. Ha H., Yu M.R., Choi Y.J., Kitamura M., Lee H.B. Role of high glucose-induced nuclear factor-κB activation in monocyte chemoattractant protein-1 expression by mesangial cells. J. Am. Soc. Nephrol. 13:2002;894-902.
27. Lee H.B., Yu M.R., Yang Y., Jiang Z., Ha H. Reactive oxygen species-regulated signaling pathways in diabetic nephropathy. J. Am. Soc. Nephrol. 14:2003;S241-S245.
28. Liotta L.A., Goldfarb R.H., Brundage R., Siegal G.P., Terranova V., Garbisa S. Effect of plasminogen activator (urokinase), plasmin, and thrombin on glycoprotein and collagenous components of basement membrane. Cancer Res. 41:1981;4629-4636.
29. Kanalas J.J., Hopfer U. Effect of TGF-. β1 and TNF-α on the plasminogen system of rat proximal tubular epithelial cells J. Am. Soc. Nephrol. 8:1997;184-192.
30. Sharma R., Khanna A., Sharma M., Savin V.J. Transforming growth factor-. β1 increases albumin permeability of isolated rat glomeruli via hydroxyl radicals Kidney Int. 58:2000;131-136.
31. Ha H., Lee H.B. Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under high glucose. Kidney Int. 58(Suppl. 77):2000;S19-S25.
32. Iglesias-De La Cruz M.C., Ruiz-Torres P., Alcami J., Diez-Marques L., Ortega-Velazquez R., Chen S., Rodriquez-puyol M., Ziyadeh F.N., Rodriguez-Puyol D. Hydrogen peroxide increases extracellular matrix mRNA through TGF-β in human mesangial cells. Kidney Int. 59:2001;87-95.
33. Lee E.A., Seo J., Jiang Z., Kwon M.K., Ha H., Lee H.B. Role of oxidative stress in high glucose-induced plasminogen activator inhibitor-1 upregulation in diabetic nephropathy. J. Am. Soc. Nephrol. 14:2003;. abstract.