Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues

Nature Biotechnology

Volumn 22, Issue 6, 2004, Pages 724-731

  Schmitt Ulms, Gerold ^a,b,e   Hansen, Kirk ^c   Liu, Jialing ^b   Cowdrey, Cynthia ^b   Yang, Jian ^b   DeArmond, Stephen J ^a,b   Cohen, Fred E ^a,b,d   Prusiner, Stanley B ^a,b,d   Baldwin, Michael A ^a,b,c  

^a Institute for Neurodegenerative Diseases   (United States)

^b Department of Neurology ^*  (United States)

^c 94143 0446   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; INTEGRAL EQUATIONS; MASS SPECTROMETRY; PROTEINS; TISSUE;

CROSS-LINKING; TISSUE INTEGRITY; TRANSCARDIAC PERFUSION;

DETERGENTS;

ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; CELL MEMBRANE PROTEIN; FIBRONECTIN; GAMMA SECRETASE; GLYCOSYLPHOSPHATIDYLINOSITOL; IMMUNOGLOBULIN; NICASTRIN; PRESENILIN 1; PRION PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ADHESION; ELECTROSPRAY MASS SPECTROMETRY; MASS SPECTROMETRY; MOUSE; NERVE CELL MEMBRANE; NERVE FIBER GROWTH; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN TARGETING; QUADRUPOLE MASS SPECTROMETRY;

AMINO ACID SEQUENCE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BLOTTING, WESTERN; BRAIN; BRAIN CHEMISTRY; CARDIAC SURGICAL PROCEDURES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; CROSS-LINKING REAGENTS; ENDOPEPTIDASES; FORMALDEHYDE; GLYCOSYLPHOSPHATIDYLINOSITOLS; IMMUNOSORBENT TECHNIQUES; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; NEURAL CELL ADHESION MOLECULES; PERFUSION; PRESENILIN-1; PROTEIN INTERACTION MAPPING; PRPC PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRYPSIN;

ANIMALIA;

EID: 2542583141     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt969     Document Type: Article

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