Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells

Biochemical Journal

Volumn 379, Issue 3, 2004, Pages 641-651

  Batty, Ian H ^a   Fleming, Ian N ^b   Downes, C Peter ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b CYCLACEL LTD   (United Kingdom)

Author keywords

Cross talk; Feedback regulation of insulin signalling; Insulin receptor substrate; Phosphoinositide 3 kinase; Phospholipase C

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; CELLS; ENZYMES; SODIUM COMPOUNDS;

CELLULAR CONCENTRATION; PHOSPHORYLATION; TYROSINE;

INSULIN;

CALCIUM ION; CARBACHOL; MITOGEN ACTIVATED PROTEIN KINASE; MUSCARINIC M3 RECEPTOR; OKADAIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; SOMATOMEDIN C RECEPTOR; VANADATE SODIUM;

ARTICLE; ASTROCYTOMA CELL; CONCENTRATION RESPONSE; ENZYME ACTIVITY; INHIBITION KINETICS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ASTROCYTOMA; CALCIUM; CARBACHOL; CELL LINE, TUMOR; ENZYME ACTIVATION; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; INSULIN; IONOMYCIN; MITOGEN-ACTIVATED PROTEIN KINASES; OKADAIC ACID; PHOSPHOLIPASE C; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOSERINE; PHOSPHOTYROSINE; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, IGF TYPE 1; RECEPTORS, MUSCARINIC; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE;

MAMMALIA;

EID: 2542538240     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031700     Document Type: Article

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