Synthesis of 13-acylamino-huprines: Different behavior of diastereomeric 13-methanesulfonamido-huprines on PPA-mediated hydrolysis

Tetrahedron

Volumn 60, Issue 25, 2004, Pages 5423-5431

  Camps, Pelayo ^a   Gómez, Elena ^a   Muñoz Torrero, Diego ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Cleavage of primary aliphatic methanesulfonamides; Cyclization reaction; Huprines; PPA; Rearrangement

Indexed keywords

12 AMINO 3 CHLORO 13 FORMAMIDO 6,7,10,11 TETRAHYDRO 9 METHYL 7,11 METHANOCYCLOOCTAQUINOLINE; 12 AMINO 3 CHLORO 13 FORMAMIDO 6,7,10,11 TETRAHYDRO 9 METHYL 7,11 METHANOCYLOOCTA[B]QUINOLINE; 12,13 DIAMINO 3 CHLORO 6,7,10,11 TETRAHYDRO 9 METHYL 7,11 METHANOCYCLOOCTA[B]QUINOLONE; 13 ACETAMIDO 12 AMINO 3 CHLORO 6,7,10,11 TETRAHYDRO 9 METHYL 7,11 METHANOCYCLOOCTA[B]QUINOLINE; 13 ACETAMIDO 12 AMINO 3 CHLORO 6,7,10,11 TETRAHYDRO 9 METHYL 7,11 METHANOCYCLOOCTAQUINOLINE; PHOSPHORIC ACID; QUINOLINE DERIVATIVE; SULFONAMIDE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; BINDING AFFINITY; CYCLIZATION; DRUG BINDING; DRUG HYDROLYSIS; DRUG SYNTHESIS; ENZYME BINDING; PRIORITY JOURNAL; STEREOCHEMISTRY; SUBSTITUTION REACTION;

EID: 2542439663     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2004.04.054     Document Type: Article

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