Synthesis of diastereomeric 13-amido-substituted huprines as potential high affinity acetylcholinesterase inhibitors

Tetrahedron

Volumn 59, Issue 23, 2003, Pages 4143-4151

  Camps, Pelayo ^a   Gómez, Elena ^a   Muñoz Torrero, Diego ^a   Font Bardia, Mercè ^a   Solans, Xavier ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Acetylcholinesterase inhibitors; Huprines; Methanesulfonamido derivatives

Indexed keywords

9,9 ETHYLENEDIOXYBICYCLO[3.3.1]NONANE 3,7 DIONE; ACETYLCHOLINESTERASE; AMIDE; AMINE; BICYCLO COMPOUND; CHOLINESTERASE INHIBITOR; NICKEL; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DIASTEREOISOMER; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME ACTIVE SITE; INFRARED SPECTROSCOPY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION; STEREOCHEMISTRY; THIN LAYER CHROMATOGRAPHY;

EID: 0037720197     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(03)00577-5     Document Type: Article

References (15)

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13. Crystallographic data (excluding structure factors) for the structures in this paper have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication numbers CCDC 196559 ( 10a ) and CCDC 196560 ( 10b ). Copies of the data can be obtained, free of charge, on application to CCDC, 12 Union Road, Cambridge CB2 1EZ, UK (fax: +44 1223-336033 or e-mail: deposit@ccdc.cam.ac.uk).
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