Synthesis, in vitro pharmacology, and molecular modeling of syn-huprines as acetylcholinesterase inhibitors

Journal of Medicinal Chemistry

Volumn 44, Issue 26, 2001, Pages 4733-4736

  Camps, P ^a   Gomez E ^a   Munoz Torrero D ^a   Badia, A ^b   Vivas, N M ^a   Barril, X ^a   Orozco, M ^a   Luque, F J ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

12 AMINO 6,7,8,11 TETRAHYDRO 7,11 METHANOCYCLOOCTA[B]QUINOLINE DERIVATIVE; CHOLINESTERASE INHIBITOR; HUPERZINE A; HUPRINE X; TACRINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHROMATOGRAPHY; CYCLIZATION; DRUG SYNTHESIS; HYDROGEN BOND; MOLECULAR MODEL; SOLVATION; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION;

ACETYLCHOLINESTERASE; AMINOQUINOLINES; ANIMALS; CATTLE; CHOLINESTERASE INHIBITORS; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HUMANS; MODELS, MOLECULAR; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035924211     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010949b     Document Type: Article

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