Wound healing: Findings of the 2005 AAOMS Research Summit

Journal of Oral and Maxillofacial Surgery

Volumn 63, Issue 10, 2005, Pages 1426-1435

  Le, Anh D ^a   Basi, David L ^b   Abubaker, A Omar ^c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHOXYESTRADIOL; ADRENOMEDULLIN; ALKYLLYSOPHOSPHOLIPID; AMYLOID BETA PROTEIN; ANABOLIC AGENT; ANGIOSTATIN; BASIC FIBROBLAST GROWTH FACTOR; BECAPLERMIN; CERIVASTATIN; EPOXOMICIN; ESTRADIOL; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LACTACYSTIN; LIPOPOLYSACCHARIDE; MEVINOLIN; NITRIC OXIDE; PARATHYROID HORMONE; PLACEBO; PRAVASTATIN; PROTEASOME INHIBITOR 1; PROTEINASE INHIBITOR; SERUM ALBUMIN; SIMVASTATIN; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN; VITRONECTIN RECEPTOR;

ANGIOGENESIS; CELL SURVIVAL; CONFERENCE PAPER; ENDOTHELIUM CELL; HIGH THROUGHPUT SCREENING; HUMAN; NONHUMAN; PHYSICAL CHEMISTRY; REGULATORY MECHANISM; SLOW RELEASE FORMULATION; WOUND HEALING;

ANIMALS; BONE MORPHOGENETIC PROTEINS; DENTAL RESEARCH; GROWTH SUBSTANCES; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEASOME ENDOPEPTIDASE COMPLEX; REGENERATION; SECOND MESSENGER SYSTEMS; SURGERY, ORAL; TRANSFORMING GROWTH FACTOR BETA; WOUND HEALING;

EID: 25144500690     PISSN: 02782391     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joms.2005.07.007     Document Type: Conference Paper

References (91)

1. J.E. Nor, P.J. Polverini Role of endothelial cell survival and death signals in angiogenesis Angiogenesis 3 1999 101
2. D.L. Gibson, S.B. Sheps, S.H. Uh Retinopathy of prematurity-induced blindness Birth weight-specific survival and the new epidemic Pediatrics 86 1990 405
3. T. Alon, I. Hemo, A. Itin Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity Nat Med 1 1995 1024
4. J. Folkman Angiogenesis in cancer, vascular, rheumatoid and other disease Nat Med 1 1995 27
5. M.A. Loots, E.N. Lamme, J. Seegelaar Differences in cellular infiltrate and extracellular matrix of chronic diabetic and venous ulcer versus acute wounds J Invest Dermatol 111 1998 850
6. B. Vasir, J.C. Jonas, G.M. Steil Gene expression of VEGF and its receptors Flk-1/KDR and Flt-1 in cultured and transplanted rat islets Transplantation 71 2001 924
7. R. Lang, M.J. Bishop Macrophages are required for cell death and tissue remodeling in the developing mouse eye Cell 74 1993 453
8. N. Ferrara, W.J. Henzel Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells Biochem Biophys Res Commun 161 1989 851
9. J. Plouet, J. Schilling, D. Gospodarowicz Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells EMBO J 8 1989 3801
10. H.F. Dvorak Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing N Engl J Med 315 1986 1650
11. D.W. Leung, G. Cachianes, W.J. Kuang Vascular endothelial growth factor is a secreted angiogenic mitogen Science 246 1989 1306
12. R.J. Melder, G.C. Koenig, B.P. Witwer During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium Nat Med 2 1996 992
13. I. Spyridopoulos, E. Brogi, M. Kearney Vascular endothelial growth factor inhibits endothelial cell apoptosis induced by tumor necrosis factor-alpha Balance between growth and death signals J Mol Cell Cardiol 29 1997 1321
14. H.P. Gerber, V. Dixit, N. Ferrara Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells J Bio Chem 273 1998 13313
15. J.E. Nor, J. Christensen, D.J. Mooney Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression Am J Pathol 154 1999 375
16. P. Carmeliet, Y. Dor, J.-M. Herbert Role of HIF-α in hypoxia-mediated apoptosis, cell proliferation, and tumor angiogenesis Nature 394 1998 485
17. J.A. Abraham, A. Mergia, J.L. Whang Nucleotide sequence of a bovine clone encoding the angiogenic protein, basic fibroblast growth factor Science 233 1986 545
18. S. Araki, Y. Simada, K. Kaji Role of protein kinase C in the inhibition by fibroblast growth factor of apoptosis in serum-depleted endothelial cells Biochem Biophys Res Commun 172 1990 1081
19. A. Karsan, E. Yee, G.G. Poirier Fibroblast growth factor-2 inhibits endothelial cell apoptosis by Bcl-2-dependent and independent mechanisms Am J Pathol 151 1997 1775
20. J. Lawler, R.O. Hynes The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins J Cell Biol 103 1986 1635
21. F. Rastinejad, P.J. Polyerini, N.P. Bouck Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene Cell 56 1989 345
22. J.E. Nor, R.S. Mitra, M.M. Sutorik Thrombospondin-1 induces endothelial cell apoptosis and inhibits angiogenesis by activating the caspase death pathway J Vasc Res 37 2000 209
23. L.A. DiPietro, D.R. Nebgen, P.J. Polverini Downregulation of endothelial cell thrombospondin 1 enhances in vitro angiogenesis J Vasc Res 31 1994 178
24. T. Tsukada, K. Eguchi, K. Migita Transforming growth factor beta 1 induces apoptotic cell death in cultured human umbilical vein endothelial cells with down-regulated expression of bcl-2 Biochem Biophys Res Commun 210 1995 1076
25. T. Naito, T. Masaki, D.J. Nikolic-Paterson Angiotensin II induces thrombospondin-1 production in human mesangial cells via p38 MAPK and JNK A mechanism for activation of latent TGF-beta1 Am J Physiol Renal Physiol 286 2004 F278
26. S.P. Andrade, T.P. Fan, G.P. Lewis Quantitative in-vivo studies on angiogenesis in a rat sponge model Br J Exp Pathol 68 1987 755
27. S.S. Kim, H. Utsunomiya, J.A. Koski Survival and function of hepatocytes on a novel three-dimensional synthetic biodegradable polymer scaffold with an intrinsic network of channels Ann Surg 228 1998 8
28. J.E. Nor, M.C. Peters, J.B. Christensen Engineering and characterization of functional human microvessels in immunodeficient mice Lab Invest 81 2001 453
29. A.J. Putnam, D.J. Mooney Tissue engineering using synthetic extracellular matrices Nat Med 2 1996 824
30. T.F. Deuel, R.M. Senior, J.S. Huang Chemotaxis of monocytes and neutrophils to platelet-derived growth factor J Clin Invest 69 1982 1046
31. T. Parekh, B. Saxena, J. Reibman Neutrophil chemotaxis in response to TGF-beta isoforms (TGF-beta 1, TGF-beta 2, TGF-beta 3) is mediated by fibronectin J Immunol 152 1994 2456
32. N. Khalil TGF-beta from latent to active Microbes Infect 1 1999 1255
33. M. Lagraoui, L. Gagnon Enhancement of human neutrophil survival and activation by TGF-beta 1 Cell Mol Biol (Noisy-le-grand) 43 1997 313
34. L. Franzen, C. Dahlquist The effect of transforming growth factor-beta on fibroblast cell proliferation in intact connective tissue in vitro In Vitro Cell Dev Biol Anim 30A 1994 460
35. K. Frazier, S. Williams, D. Kothapalli Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor J Invest Dermatol 107 1996 404
36. R.Y. Lin, K.M. Sullivan, P.A. Argenta Exogenous transforming growth factor-beta amplifies its own expression and induces scar formation in a model of human fetal skin repair Ann Surg 222 1995 146
37. D.V. Messadi, A. Le, S. Berg Effect of TGF-beta 1 on PDGF receptors expression in human scar fibroblasts Front Biosci 3 1998 a16
38. K. Tiku, M.L. Tiku, J.L. Skosey Interleukin 1 production by human polymorphonuclear neutrophils J Immunol 136 1986 3677
39. S.J. Klebanoff, M.A. Vadas, J.M. Harlan Stimulation of neutrophils by tumor necrosis factor J Immunol 136 1986 4220
40. G.W. Prager, J.M. Breuss, S. Steurer Vascular endothelial growth factor (VEGF) induces rapid prourokinase (pro-uPA) activation on the surface of endothelial cells Blood 103 2004 955
41. W. Li, J. Fan, M. Chen Mechanism of human dermal fibroblast migration driven by type I collagen and platelet-derived growth factor-BB Mol Biol Cell 15 2004 294
42. T. Asahara, T. Takahashi, H. Masuda VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells EMBO J 18 1999 3964
43. Y. Xu, H. Arai, X. Zhuge Role of bone marrow-derived progenitor cells in cuff-induced vascular injury in mice Arterioscler Thromb Vasc Biol 24 2004 477
44. R.D. Paladini, K. Takahashi, N.S. Bravo Onset of re-epithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes Defining a potential role for keratin J Cell Biol 132 1996 381
45. U. auf DemKeller, M. Krampert, A. Kumin Keratinocyte growth factor effects on keratinocytes and mechanisms of action Eur J Cell Biol 83 2004 607
46. R.A. Clark, H.J. Winn, H.F. Dvorak Fibronectin beneath reepithelializing epidermis in vivo sources and significance J Invest Dermatol 80 suppl 1983 26s
47. Y.H. Kang, V.P. Kedar, R.K. Maheshwari Thrombin stimulation of synthesis and secretion of fibronectin by human A549 epithelial cells and mouse LB fibroblasts J Histochem Cytochem 39 1991 413
48. N. Guo, H.C. Krutzsch, J.K. Inman Thrombospondin 1 and type I repeat peptides of thrombospondin 1 specifically induce apoptosis of endothelial cells Cancer Res 57 1997 1735
49. M. Streit, L. Riccardi, P. Velasco Thrombospondin-2 a potent endogenous inhibitor of tumor growth and angiogenesis Proc Natl Acad Sci U S A 96 1999 14888
50. Y. Akasaka, I. Ono, T. Yamashita Basic fibroblast growth factor promotes apoptosis and suppresses granulation tissue formation in acute incisional wounds J Pathol 203 2004 710
51. K. Yasuda, K. Aoshiba, A. Nagai Transforming growth factor beta promotes fibroblast apoptosis induced by hydrogen peroxide Exp Lung Res 29 2003 123
52. A. Tingstrom, C.H. Heldin, K. Rubin Regulation of fibroblast-mediated collagen gel contraction by platelet-derived growth factor, interleukin-1 alpha and transforming growth factor-beta 1 J Cell Sci 102 1992 315
53. J.W. Madden, E.E. Peacock Jr Studies on the biology of collagen during wound healing. 3. Dynamic metabolism of scar collagen and remodeling of dermal wounds Ann Surg 174 1971 511
54. W.T. Bourque, M. Gross, B.K. Hall Expression of four growth factors during fracture repair Int J Dev Biol 37 1993 573
55. J. Fiedler, G. Roderer, K.P. Gunther BMP-2, BMP-4, and PDGF-bb stimulate chemotactic migration of primary human mesenchymal progenitor cells J Cell Biochem 87 2002 305
56. M.P. Bostrom, J.M. Lane, W.S. Berberian Immunolocalization and expression of bone morphogenetic proteins 2 and 4 in fracture healing J Orthop Res 13 1995 357
57. I. Asahina, T.K. Sampath, P.V. Hauschka Human osteogenic protein-1 induces chondroblastic, osteoblastic, and/or adipocytic differentiation of clonal murine target cells Exp Cell Res 222 1996 38
58. J.G. Andrew, J. Hoyland, A.J. Freemont Insulinlike growth factor gene expression in human fracture callus Calcif Tissue Int 53 1993 97
59. C. Palermo, P. Manduca, E. Gazzero Potentiating role of IGFBP-2 on IGF-II-stimulated alkaline phosphatase activity in differentiating osteoblasts Am J Physiol Endocrinol Metab 286 2003 E648
60. H. Mochizuki, Y. Hakeda, N. Wakatsuki Insulin-like growth factor-I supports formation and activation of osteoclasts Endocrinology 131 1992 1075
61. M. Nakagawa, T. Kaneda, T. Arakawa Vascular endothelial growth factor (VEGF) directly enhances osteoclastic bone resorption and survival of mature osteoclasts FEBS Lett 473 2000 161
62. R. Sen, D. Baltimore Multiple nuclear factors interact with the immunoglobulin enhancer sequences Cell 46 1986 705
63. M. Delhase, M. Hayakawa, Y. Chen Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation Science 284 1999 309
64. Y. Hu, V. Baud, M. Delhase Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase Science 284 1999 316
65. P.A. Baeuerle, D. Baltimore NF-kappa B Ten years after Cell 87 1996 13
66. C. Kunsch, R.M. Medford Oxidative stress as a regulator of gene expression in the vasculature Circ Res 85 1999 753
67. Z. Guan, D. Basi, Q. Li Loss of redox factor 1 decreases NF-Kappa B activity and increases susceptibility of endothelial cells to apoptosis Arterioscler Thromb Vasc Biol 5 2005 96
68. M.R. Urist Bone formation by autoinduction Science 150 1965 893
69. G.R. Mundy Local factors in bone remodeling Recent Prog Horm Res 45 1989 507
70. P.J. Harwood, P.V. Giannoudis Application of bone morphogenetic proteins in orthopaedic practice Their efficacy and side effects Expert Opin Drug Saf 4 2005 75
71. G. Mundy, R. Garrett, S. Harris Stimulation of bone formation in vitro and in rodents by statins Science 286 1999 1946
72. D.C. Bauer, G.R. Mundy, S.A. Jamal Statin use, bone mass and fracture An analysis of two prospective studies J Bone Min Res 14 1999 1188
73. J.A. Cauley, R. Jackson, M. Pettinger Statin use and bone mineral density in older women The Women's Health Initiative Observational Study (WHI-OS) J Bone Min Res 15 suppl 2000 155
74. I.R. Garrett, D. Chen, G. Gutierrez Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro J Clin Invest 111 2003 1771
75. J. Adams, V.J. Palombella, E.A. Sausville Proteasome inhibitors A novel class of potent and effective antitumor agents Cancer Res 59 1999 2615
76. T.J. Wieman, J.M. Smiell, Y. Su Efficacy and safety of a topical gel formulation of recombinant human platelet-derived growth factor-BB (Becaplermin) in patients with non healing diabetic ulcers A phase III, randomized, placebo-controlled, double-blind study Diabetes Care 21 1998 822
77. S.G. Keswani, A.B. Katz, F.Y. Lim Adenoviral mediated gene transfer of PDGF-B enhances wound healing in type I and type II diabetic wounds Wound Repair Regen 12 2004 497
78. A. Rivard, M. Silver, D. Chen Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF Am J Pathol 154 1999 355
79. R.E. Marx, R.P. Johnson Studies in the radiobiology of osteoradionecrosis and their clinical significance Oral Surg Oral Med Oral Rad 64 1987 379
80. E. Ducasse, J.M. Cosset, J. Mazurier High-dose external ionizing radiation prevents intimal hyperplasia and limits secretion of growth factors PDGFbb, bFGF, and TGFb1 Experiments and results J Mal Vasc 28 2003 68
81. M.E. Dudziak, P.B. Saadeh, B.J. Mehrara The effects of ionizing radiation on osteoblast-like cells in vitro Plast Reconstr Surg 106 2000 1049
82. T.L. Aghaloo, A.D. Le Dental implant site preservation and development in oral and maxillofacial surgery Oral Maxillofacial Surg Clin N Am 16 2004 111
83. E.F. Bernstein, L. Harisiadis, G. Salomon Transforming growth factor-beta improves healing of radiation-impaired wounds J Invest Dermatol 97 1991 430
84. D.T. Cromack, B. Porras-Reyes, J.A. Purdy Acceleration of tissue repair by transforming growth factor beta 1 Identification of in vivo mechanism of action with radiotherapy-induced specific healing deficits Surgery 113 1993 36
85. A.V. Nall, R.E. Brownlee, C.P. Colvin Transforming growth factor beta 1 improves wound healing and random flap survival in normal and irradiated rats Arch Otolaryngol Head Neck Surg 122 1996 171
86. U. Wollina, K. Liebold, H. Konrad Treatment of chronic radiation ulcers with recombinant platelet-derived growth factor and a hydrophilic copolymer membrane J Eur Acad Dermatol Venereol 15 2001 455
87. T.A. Mustoe, J. Purdy, P. Gramates Reversal of impaired wound healing in irradiated rats by platelet-derived growth factor-BB Am J Surg 158 1989 345
88. S. Ruggiero, T.J. Rosenberg Osteonecrosis of the jaws associated with the use of bisphosphonates J Oral Maxillofac Surg 62 2004 527
89. L.A. Assael New foundation in understanding osteonecrosis of the jaws J Oral Maxillofac Surg 62 2004 125
90. R.E. Marx Pamidronate (Aredia) and Zoledronate (Zometa) induced avascular necrosis of the jaws A growing epidemic [letter] J Oral Maxillofac Surg 61 2003 115
91. H. Li, Z. Pujic, Y. Xiao Identification of bone morphogenetic proteins 2 and 4 in commercial demineralized freeze-dried bone allograft preparations Pilot study Clin Implant Dent Relat Res 2 2000 110