Pooling samples within microarray studies: A comparative analysis of rat liver transcription response to prototypical toxicants

Physiological Genomics

Volumn 22, Issue , 2005, Pages 346-355

  Jolly, Robert A ^a   Goldstein, Keith M ^a   Wei, Tao ^a   Gao, Hong ^a   Chen, Peining ^a   Huang, Shuguang ^a   Colet, Jean Marie ^b   Ryan, Timothy P ^a   Thomas, Craig E ^a   Estrem, Shawn T ^a  

^a ELI LILLY AND COMPANY   (United States)

^b Eli Lilly Benelux   (Belgium)

Author keywords

Affymetrix microarray; Hepatotoxicants; Statistical

Indexed keywords

ALDEHYDE REDUCTASE; ALPHA LEVO FUCOSIDASE; ASIALOGLYCOPROTEIN; CARBOXYLESTERASE; CHOLESTEROL ESTERASE; CLOFIBRATE; COMPLEMENTARY DNA; GLUCURONOSYLTRANSFERASE; HYDROLYASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; KYNURENINE 3 MONOOXYGENASE; LONG CHAIN FATTY ACID COENZYME A LIGASE; MESSENGER RNA; PHOSPHOPROTEIN PHOSPHATASE 1; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; RETINOL DEHYDROGENASE; SELENOPROTEIN; STEROL 14ALPHA DEMETHYLASE; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA MICROARRAY; GENE EXPRESSION; LIVER TOXICITY; LIVER WEIGHT; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAMPLING;

ANIMALS; CLOFIBRATE; CLUSTER ANALYSIS; DIETHYLHEXYL PHTHALATE; FATTY ACIDS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LIVER; LIVER EXTRACTS; MALE; MITOCHONDRIA; MODELS, BIOLOGICAL; MODELS, STATISTICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGAN SIZE; PHENOTYPE; PHYLOGENY; PRINCIPAL COMPONENT ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER; TRANSCRIPTION, GENETIC; VALPROIC ACID;

ANIMALIA;

EID: 25144478254     PISSN: 15312267     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00260.2004     Document Type: Article

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