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Volumn 4, Issue 5, 2005, Pages 602-611

High concentrations of retinoids induce differentiation and late apoptosis in pancreatic cancer cells in vitro

Author keywords

Apoptosis; Pancreatic cancer; Retinoic acid

Indexed keywords

CARBONATE DEHYDRATASE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MUCIN; RECEPTOR BLOCKING AGENT; RETINOIC ACID RECEPTOR ALPHA; RETINOID; RO 415253; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 25144444831     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.4.5.1762     Document Type: Article
Times cited : (27)

References (63)
  • 1
    • 0034041801 scopus 로고    scopus 로고
    • Pancreatic cancer. A review of emerging therapies
    • Rosenberg L. Pancreatic cancer. A review of emerging therapies. Drugs 2000; 59:1071-89.
    • (2000) Drugs , vol.59 , pp. 1071-1089
    • Rosenberg, L.1
  • 2
    • 0033953188 scopus 로고    scopus 로고
    • Molecular biology of pancreatic cancer; oncogenes, tumor suppressor genes, growth factors, and their receptors from a clinical perspective
    • Sakorafas GH, Tsiotou AG, Tsiotos GG. Molecular biology of pancreatic cancer; oncogenes, tumor suppressor genes, growth factors, and their receptors from a clinical perspective. Cancer Treat Rev 2000; 26:29-52.
    • (2000) Cancer Treat Rev , vol.26 , pp. 29-52
    • Sakorafas, G.H.1    Tsiotou, A.G.2    Tsiotos, G.G.3
  • 3
    • 0034235955 scopus 로고    scopus 로고
    • Epidermal growth factor receptor blockade by antibody IMC-C225 inhibits growth of a human pancreatic carcinoma xenograft in nude mice
    • Overholser JP, Prewett MC, Hooper AT, Waksal HW, Hicklin DJ. Epidermal growth factor receptor blockade by antibody IMC-C225 inhibits growth of a human pancreatic carcinoma xenograft in nude mice. Cancer 2000; 89:74-82.
    • (2000) Cancer , vol.89 , pp. 74-82
    • Overholser, J.P.1    Prewett, M.C.2    Hooper, A.T.3    Waksal, H.W.4    Hicklin, D.J.5
  • 4
    • 0033065168 scopus 로고    scopus 로고
    • Serum and correspondent tissue measurements of epidermal growth factor (EGF) and epidermal growth factor receptor (EGF-R). Clinical relevance in pancreatic cancer and chronic pancreatitis
    • Birk D, Gansauge F, Gansauge S, Formentini A, Lucht A, Beger HG. Serum and correspondent tissue measurements of epidermal growth factor (EGF) and epidermal growth factor receptor (EGF-R). Clinical relevance in pancreatic cancer and chronic pancreatitis. Int J Pancreatol 1999; 25:89-96.
    • (1999) Int J Pancreatol , vol.25 , pp. 89-96
    • Birk, D.1    Gansauge, F.2    Gansauge, S.3    Formentini, A.4    Lucht, A.5    Beger, H.G.6
  • 7
    • 0026459590 scopus 로고
    • Decreased expression of transforming growth factor-α during differentiation of human pancreatic cancer cells
    • Estival A, Clerc P, Vaysse N, Tam JP, Clemente F. Decreased expression of transforming growth factor-α during differentiation of human pancreatic cancer cells. Gastroenterology 1992; 103:1851-9.
    • (1992) Gastroenterology , vol.103 , pp. 1851-1859
    • Estival, A.1    Clerc, P.2    Vaysse, N.3    Tam, J.P.4    Clemente, F.5
  • 8
    • 0001744237 scopus 로고    scopus 로고
    • Retinoic acid normalized the increased gene transcription rate of TGF-α and EGFR in head and neck cancer cell lines
    • Grandis JR, Zeng Q, Tweardy DJ. Retinoic acid normalized the increased gene transcription rate of TGF-α and EGFR in head and neck cancer cell lines. Nature Med 1996; 2:237-40.
    • (1996) Nature Med , vol.2 , pp. 237-240
    • Grandis, J.R.1    Zeng, Q.2    Tweardy, D.J.3
  • 9
    • 14444284330 scopus 로고    scopus 로고
    • Tumor-suppressive pathways in pancreatic carcinoma
    • Rozenblum E, Schutte M, Goggins M, et al. Tumor-suppressive pathways in pancreatic carcinoma. Cancer Res 1997; 57:1731-4.
    • (1997) Cancer Res , vol.57 , pp. 1731-1734
    • Rozenblum, E.1    Schutte, M.2    Goggins, M.3
  • 10
    • 0030659033 scopus 로고    scopus 로고
    • Different expression of TGF-β1 in pancreatic ductal adenocarcinoma and cystic neoplasms
    • van Laethem J-L, Resibios A, Rickaert F, et al. Different expression of TGF-β1 in pancreatic ductal adenocarcinoma and cystic neoplasms. Pancreas 1997; 15:41-7.
    • (1997) Pancreas , vol.15 , pp. 41-47
    • Van Laethem, J.-L.1    Resibios, A.2    Rickaert, F.3
  • 11
    • 0031957710 scopus 로고    scopus 로고
    • Expression of transforming growth factor β1 and its receptors in pancreatic duct cell carcinoma and in chronic pancreatitis
    • Satoh K, Shimosegawa T, Hirota M, Koizumi M, Toyota T. Expression of transforming growth factor β1 and its receptors in pancreatic duct cell carcinoma and in chronic pancreatitis. Pancreas 1998; 16:468-74.
    • (1998) Pancreas , vol.16 , pp. 468-474
    • Satoh, K.1    Shimosegawa, T.2    Hirota, M.3    Koizumi, M.4    Toyota, T.5
  • 13
    • 0025759209 scopus 로고
    • Induction of transforming growth factor-β 1 (TGF-β 1), receptor expression and TGF-β 1 protein production in retinoic acid-treated HL-60 cells: Possible TGF-β 1-mediated autocrine inhibition
    • Falk LA, De Benedetti F, Lohrey N, Birchenall-Roberts MC, Ellingsworth LW, Faltynek CR, Ruscetti FW. Induction of transforming growth factor-β 1 (TGF-β 1), receptor expression and TGF-β 1 protein production in retinoic acid-treated HL-60 cells: possible TGF-β 1-mediated autocrine inhibition. Blood 1991; 77:1248-55.
    • (1991) Blood , vol.77 , pp. 1248-1255
    • Falk, L.A.1    De Benedetti, F.2    Lohrey, N.3    Birchenall-Roberts, M.C.4    Ellingsworth, L.W.5    Faltynek, C.R.6    Ruscetti, F.W.7
  • 14
    • 0030612484 scopus 로고    scopus 로고
    • waf1 expression and growth inhibition by transforming factor-β involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells
    • waf1 expression and growth inhibition by transforming factor-β involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells. Cancer Res 1997; 57:3929-34.
    • (1997) Cancer Res , vol.57 , pp. 3929-3934
    • Grau, A.M.1    Zhang, L.2    Wang, W.3
  • 15
    • 0029810920 scopus 로고    scopus 로고
    • Attenuated ALK5 receptor expression in human pancreatic cancer: Correlation with resistance to growth inhibition
    • Baldwin RL, Friess H, Yokoyama M, Lopez ME, Kobrin MS. Attenuated ALK5 receptor expression in human pancreatic cancer: Correlation with resistance to growth inhibition. Int J Cancer 1996; 67:283-8.
    • (1996) Int J Cancer , vol.67 , pp. 283-288
    • Baldwin, R.L.1    Friess, H.2    Yokoyama, M.3    Lopez, M.E.4    Kobrin, M.S.5
  • 16
    • 84861236243 scopus 로고    scopus 로고
    • Oncogenic ras downregulates the TGF-β type II receptor expression in pancreatic cancer
    • Freeman J, Venkatasubbarao K, Ahmed M, et al. Oncogenic ras downregulates the TGF-β type II receptor expression in pancreatic cancer. Proc Am Assoc Cancer Res 1998; 39:195.
    • (1998) Proc Am Assoc Cancer Res , vol.39 , pp. 195
    • Freeman, J.1    Venkatasubbarao, K.2    Ahmed, M.3
  • 17
    • 0030960368 scopus 로고    scopus 로고
    • All-trans retinoic acid increases TGF-β2 and insulin-like growth factor binding protein-3 expression through a retinoic acid receptor-a-dependent signaling pathway
    • Han G-R, Dohi DF, Lee H-Y, et al. All-trans retinoic acid increases TGF-β2 and insulin-like growth factor binding protein-3 expression through a retinoic acid receptor-a-dependent signaling pathway. J Biol Chem 1997; 272:13711-6.
    • (1997) J Biol Chem , vol.272 , pp. 13711-13716
    • Han, G.-R.1    Dohi, D.F.2    Lee, H.-Y.3
  • 18
    • 0030610532 scopus 로고    scopus 로고
    • Overexpression of the TGF-β-regulated zinc finger encoding gene, TIEG, induces apoptosis in pancreatic epithelial cells
    • Tachibana I, Imoto M, Adjei PN, et al. Overexpression of the TGF-β-regulated zinc finger encoding gene, TIEG, induces apoptosis in pancreatic epithelial cells. J Clin Invest 1997; 99:2365-74.
    • (1997) J Clin Invest , vol.99 , pp. 2365-2374
    • Tachibana, I.1    Imoto, M.2    Adjei, P.N.3
  • 19
    • 0031858069 scopus 로고    scopus 로고
    • Retinoids potentiate TGF-β in bovine endothelial cells through upregulating the expression of TGF-β receptors
    • Yoshizawa M, Miyazaki H, Kojima S. Retinoids potentiate TGF-β in bovine endothelial cells through upregulating the expression of TGF-β receptors. J Cell Physiol 1998; 176:565-73.
    • (1998) J Cell Physiol , vol.176 , pp. 565-573
    • Yoshizawa, M.1    Miyazaki, H.2    Kojima, S.3
  • 20
    • 16944366824 scopus 로고    scopus 로고
    • Novel retinoid-related molecules as apoptosis inducers and effective inhibitors of human lung cancer cells in vivo
    • Lu X-P, Fanjul A, Picard N, et al. Novel retinoid-related molecules as apoptosis inducers and effective inhibitors of human lung cancer cells in vivo. Nature Med 1997; 3:686-90.
    • (1997) Nature Med , vol.3 , pp. 686-690
    • Lu, X.-P.1    Fanjul, A.2    Picard, N.3
  • 21
    • 0033551126 scopus 로고    scopus 로고
    • Optimization of treatment conditions for studying the anticancer effects of retinoids using pancreatic adenocarcinoma as a model
    • El-Metwally TH, Adrian TE. Optimization of treatment conditions for studying the anticancer effects of retinoids using pancreatic adenocarcinoma as a model. Biochem Biophys Res Comm 1999; 257:596-603.
    • (1999) Biochem Biophys Res Comm , vol.257 , pp. 596-603
    • El-Metwally, T.H.1    Adrian, T.E.2
  • 22
    • 0032998309 scopus 로고    scopus 로고
    • Overcoming Bcl-2- and p53-mediated resistance in prostate cancer
    • DiPaola RS, Aisner J. Overcoming Bcl-2- and p53-mediated resistance in prostate cancer. Semin Oncolg 1999; 26:112-6.
    • (1999) Semin Oncolg , vol.26 , pp. 112-116
    • DiPaola, R.S.1    Aisner, J.2
  • 23
    • 0027489864 scopus 로고
    • Growth control or terminal differentiation: Endogenous production and differential activities of vitamin A metabolites in HL-60 cells
    • Eppinger TM, Buck J, Hammerling U. Growth control or terminal differentiation: Endogenous production and differential activities of vitamin A metabolites in HL-60 cells. J Exp Med 1993; 178:1995-2005.
    • (1993) J Exp Med , vol.178 , pp. 1995-2005
    • Eppinger, T.M.1    Buck, J.2    Hammerling, U.3
  • 24
    • 0029793892 scopus 로고    scopus 로고
    • RAR and RXR selective ligands cooperatively induce apoptosis and neuronal differentiation in P19 embryonal carcinoma cells
    • Horn V, Minucci S, Ogryzko V, et al. RAR and RXR selective ligands cooperatively induce apoptosis and neuronal differentiation in P19 embryonal carcinoma cells. FASEB J 1996; 10:1071-7.
    • (1996) FASEB J , vol.10 , pp. 1071-1077
    • Horn, V.1    Minucci, S.2    Ogryzko, V.3
  • 25
    • 0028787351 scopus 로고
    • Retinoids and apoptosis: Implications for cancer chemoprevention and therapy
    • Lotan R. Retinoids and apoptosis: Implications for cancer chemoprevention and therapy. J Natl Cancer Inst 1995; 87:1655-7.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1655-1657
    • Lotan, R.1
  • 26
    • 0031945458 scopus 로고    scopus 로고
    • Cell cycle regulation and apoptosis
    • King KL, Cidlowski JA. Cell cycle regulation and apoptosis. Annu Rev Physiol 1998; 60:601-17.
    • (1998) Annu Rev Physiol , vol.60 , pp. 601-617
    • King, K.L.1    Cidlowski, J.A.2
  • 27
    • 0031616983 scopus 로고    scopus 로고
    • Special topic: Apoptosis
    • Thompson B. Special topic: Apoptosis. Annu Rev Physiol 1998; 60:525-31.
    • (1998) Annu Rev Physiol , vol.60 , pp. 525-531
    • Thompson, B.1
  • 28
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Masmann TR. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol 1983; 65:55-63.
    • (1983) J Immunol , vol.65 , pp. 55-63
    • Masmann, T.R.1
  • 29
    • 0014011587 scopus 로고
    • Purification and properties of human erythrocyte carbonic anhydrase
    • Armstrong J McD, Myers DV, Verpoorte JA, Edsall JT. Purification and properties of human erythrocyte carbonic anhydrase. J Biol Chem 1966; 241:5137-49.
    • (1966) J Biol Chem , vol.241 , pp. 5137-5149
    • Armstrong, J.McD.1    Myers, D.V.2    Verpoorte, J.A.3    Edsall, J.T.4
  • 30
    • 0022909840 scopus 로고
    • Total and lipid-associated serum sialic acid levels in cancer patients with different primary sites and differing degrees of metastatic involvement
    • Plucinsky MC, Riley WM, Prprok JJ, Alhadeff JA. Total and lipid-associated serum sialic acid levels in cancer patients with different primary sites and differing degrees of metastatic involvement. Cancer 1986; 58:2680-5.
    • (1986) Cancer , vol.58 , pp. 2680-2685
    • Plucinsky, M.C.1    Riley, W.M.2    Prprok, J.J.3    Alhadeff, J.A.4
  • 32
    • 0028107783 scopus 로고
    • Humoral growth factors in plasma and liver tissue during liver regeneration and malnutrition
    • Skullman S, Adrian TE, Permert J, Larsson J. Humoral growth factors in plasma and liver tissue during liver regeneration and malnutrition. Eur J Gastroenterol Hepatol 1994; 6:797-802.
    • (1994) Eur J Gastroenterol Hepatol , vol.6 , pp. 797-802
    • Skullman, S.1    Adrian, T.E.2    Permert, J.3    Larsson, J.4
  • 33
    • 0025240654 scopus 로고
    • Rate constant for binding, dissociation and internalization of EGF: Effect of receptor occupancy and ligand concentration
    • Waters CM, Oberg KC, Carpenter G, Overholser KA. Rate constant for binding, dissociation and internalization of EGF: Effect of receptor occupancy and ligand concentration. Biochemistry 1990; 29:3563-9.
    • (1990) Biochemistry , vol.29 , pp. 3563-3569
    • Waters, C.M.1    Oberg, K.C.2    Carpenter, G.3    Overholser, K.A.4
  • 34
    • 0030944855 scopus 로고    scopus 로고
    • Effects of all-trans retinoic acid and 13-cis retinoic acid on breast cancer cell lines: Growth inhibition and apoptosis induction
    • Toma S, Isnardi L, Raffo P, et al. Effects of all-trans retinoic acid and 13-cis retinoic acid on breast cancer cell lines: Growth inhibition and apoptosis induction. Int J Cancer 1997; 70:619-27.
    • (1997) Int J Cancer , vol.70 , pp. 619-627
    • Toma, S.1    Isnardi, L.2    Raffo, P.3
  • 35
    • 0000147542 scopus 로고    scopus 로고
    • Recent advances in chemoprevention of cancer
    • Hong WK, Sporn MB. Recent advances in chemoprevention of cancer. Science 1997; 278:1073-7.
    • (1997) Science , vol.278 , pp. 1073-1077
    • Hong, W.K.1    Sporn, M.B.2
  • 36
    • 0000602007 scopus 로고    scopus 로고
    • Acquisition of cell adhesion and induction of focal adhesion kinase of human colon cancer Colo 201 cells by retinoic acid-induced differentiation
    • Nakagawa K, Sogo S, Hioki K, Tokunaga R, Taketani S. Acquisition of cell adhesion and induction of focal adhesion kinase of human colon cancer Colo 201 cells by retinoic acid-induced differentiation. Differentiation 1998; 62:249-57.
    • (1998) Differentiation , vol.62 , pp. 249-257
    • Nakagawa, K.1    Sogo, S.2    Hioki, K.3    Tokunaga, R.4    Taketani, S.5
  • 37
    • 0022632542 scopus 로고
    • Butyrate induced reduction of tumor cell laminin receptors
    • Bryant G, Haberern C, Rao CN, Liotta LA. Butyrate induced reduction of tumor cell laminin receptors. Cancer Res 1986; 46:807-11.
    • (1986) Cancer Res , vol.46 , pp. 807-811
    • Bryant, G.1    Haberern, C.2    Rao, C.N.3    Liotta, L.A.4
  • 38
    • 0029731366 scopus 로고    scopus 로고
    • Redifferentiation and apoptosis of pancreatic cells during acute pancreatitis
    • Iovanna JL. Redifferentiation and apoptosis of pancreatic cells during acute pancreatitis. Int J Pancreatol 1996; 20:77-84.
    • (1996) Int J Pancreatol , vol.20 , pp. 77-84
    • Iovanna, J.L.1
  • 39
    • 0003913634 scopus 로고    scopus 로고
    • Evidence for interactions between rat hepatoma cell apoptosis and differentiation
    • Renault E, Sarrazin S, Deschatrette J. Evidence for interactions between rat hepatoma cell apoptosis and differentiation. Biochem Genet 1998; 36:1-13.
    • (1998) Biochem Genet , vol.36 , pp. 1-13
    • Renault, E.1    Sarrazin, S.2    Deschatrette, J.3
  • 40
    • 0028253708 scopus 로고
    • Retrodifferentiation and cell death
    • Hass R. Retrodifferentiation and cell death. Crit Rev Oncog 1994; 5:359-71.
    • (1994) Crit Rev Oncog , vol.5 , pp. 359-371
    • Hass, R.1
  • 41
    • 0033602739 scopus 로고    scopus 로고
    • bFGF suppresses serum-deprivation-induced apoptosis in a human lens epithelial cell line
    • Wang Y, He H, Zigler J, et al. bFGF suppresses serum-deprivation-induced apoptosis in a human lens epithelial cell line. Exp Cell Res 1999; 249:123-30.
    • (1999) Exp Cell Res , vol.249 , pp. 123-130
    • Wang, Y.1    He, H.2    Zigler, J.3
  • 42
    • 0032925793 scopus 로고    scopus 로고
    • Restoration of wild-type PTEN expression leads to apoptosis, induces differentiation and reduces telomerase activity in human glioma cells
    • Tian X, Pang J, To S, Ng H. Restoration of wild-type PTEN expression leads to apoptosis, induces differentiation and reduces telomerase activity in human glioma cells. J Neuropathol Exp Neurol 1999; 58:472-9.
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 472-479
    • Tian, X.1    Pang, J.2    To, S.3    Ng, H.4
  • 43
    • 0028574131 scopus 로고
    • The expression of carbonic anhydrase II and IV in the human pancreatic cancer cell line Capan-1 is associated with bicarbonate ion channels
    • Mahieu I, Becq F, Wolfensberger T, et al. The expression of carbonic anhydrase II and IV in the human pancreatic cancer cell line Capan-1 is associated with bicarbonate ion channels. Biol Cell 1994; 81:131-41.
    • (1994) Biol Cell , vol.81 , pp. 131-141
    • Mahieu, I.1    Becq, F.2    Wolfensberger, T.3
  • 44
    • 0025075919 scopus 로고
    • Carbonic anhydrase gene expression in cell lines from human pancreatic adenocarcinoma
    • Frazier ML, Lilly BJ, Wu EF, Ota T, Hewett-Emmett D. Carbonic anhydrase gene expression in cell lines from human pancreatic adenocarcinoma. Pancreas 1990; 5:507-14.
    • (1990) Pancreas , vol.5 , pp. 507-514
    • Frazier, M.L.1    Lilly, B.J.2    Wu, E.F.3    Ota, T.4    Hewett-Emmett, D.5
  • 45
    • 0026600385 scopus 로고
    • 1-α,25-dihydroxy-vitamin D3 regulates the transcription of carbonic anhydrase II mRNA in avian myelo-monocytes
    • Lomri A, Baron R. 1-α,25-dihydroxy-vitamin D3 regulates the transcription of carbonic anhydrase II mRNA in avian myelo-monocytes. Cell Biol 1992; 89:4688-92.
    • (1992) Cell Biol , vol.89 , pp. 4688-4692
    • Lomri, A.1    Baron, R.2
  • 46
    • 0342656619 scopus 로고    scopus 로고
    • Differential regulation of the carbonic anhydrase II gene expression by hormonal nuclear receptors in monocytic cells: Identification of the retinoic acid response element
    • Quelo I, Jurdic P. Differential regulation of the carbonic anhydrase II gene expression by hormonal nuclear receptors in monocytic cells: Identification of the retinoic acid response element. Biochem Biophys Res Commun 2000; 271:481-91.
    • (2000) Biochem Biophys Res Commun , vol.271 , pp. 481-491
    • Quelo, I.1    Jurdic, P.2
  • 47
    • 0031598310 scopus 로고    scopus 로고
    • Apoptosis-gene expression in hematopoietic system: Normal and pathological conditions
    • Hatake K, Tomizuka H, Ikeda M, Terui Y, Miura Y. Apoptosis-gene expression in hematopoietic system: Normal and pathological conditions. Int J Mol Med 1998; 1:121-9.
    • (1998) Int J Mol Med , vol.1 , pp. 121-129
    • Hatake, K.1    Tomizuka, H.2    Ikeda, M.3    Terui, Y.4    Miura, Y.5
  • 48
    • 0032917188 scopus 로고    scopus 로고
    • Differentiation-related changes in the cell cycle traverse
    • Studzinski GP, Harrison LE. Differentiation-related changes in the cell cycle traverse. Int Rev Cytolo 1999; 189:1-58.
    • (1999) Int Rev Cytolo , vol.189 , pp. 1-58
    • Studzinski, G.P.1    Harrison, L.E.2
  • 49
    • 0034721852 scopus 로고    scopus 로고
    • Retinoic acid-dependent TGF-β2-mediated induction of MUC4 mucin expression in human pancreatic tumor cells follows RAR-α signaling pathway
    • Choudhury A, Singh RK, Moniaux N, El-Metwally TH, Aubert JP, Batra SK. Retinoic acid-dependent TGF-β2-mediated induction of MUC4 mucin expression in human pancreatic tumor cells follows RAR-α signaling pathway. J Biol Chem 2000; 275:33929-36.
    • (2000) J Biol Chem , vol.275 , pp. 33929-33936
    • Choudhury, A.1    Singh, R.K.2    Moniaux, N.3    El-Metwally, T.H.4    Aubert, J.P.5    Batra, S.K.6
  • 50
    • 0033104859 scopus 로고    scopus 로고
    • Role of retinoid receptors in the regulation of mucin gene expression by retinoic acid in human tracheobronchial epithelial cells
    • Koo J, Jetten A, Belloni P, et al. Role of retinoid receptors in the regulation of mucin gene expression by retinoic acid in human tracheobronchial epithelial cells. Biochem J 1999; 338:351-7.
    • (1999) Biochem J , vol.338 , pp. 351-357
    • Koo, J.1    Jetten, A.2    Belloni, P.3
  • 51
    • 0032568329 scopus 로고    scopus 로고
    • Stable reintroduction of wild type p53 (MTmp53ts) causes the induction of apoptosis and neuroendocrine-like differentiation in human ductal pancreatic carcinoma cells
    • Lang D, Miknyoczki SJ, Huang L, Ruggeri BA. Stable reintroduction of wild type p53 (MTmp53ts) causes the induction of apoptosis and neuroendocrine-like differentiation in human ductal pancreatic carcinoma cells. Oncogene 1998; 16:1593-602.
    • (1998) Oncogene , vol.16 , pp. 1593-1602
    • Lang, D.1    Miknyoczki, S.J.2    Huang, L.3    Ruggeri, B.A.4
  • 52
    • 0029798144 scopus 로고    scopus 로고
    • Differentiation of pancreatic carcinoma induced by retinoic acid or sodium butyrate: A morphological and molecular analysis of four cell lines
    • Egawa N, Maillet B, VanDamme B, De Greve J, Kloppel G. Differentiation of pancreatic carcinoma induced by retinoic acid or sodium butyrate: A morphological and molecular analysis of four cell lines. Verchows Arch 1996; 429:59-68.
    • (1996) Verchows Arch , vol.429 , pp. 59-68
    • Egawa, N.1    Maillet, B.2    VanDamme, B.3    De Greve, J.4    Kloppel, G.5
  • 54
    • 0031047842 scopus 로고    scopus 로고
    • Retinoids inhibit adhesion to laminin in human pancreatic carcinoma cells via the alpha 6 beta 1-integrin receptor
    • Rosewicz S, Wollbergs K, Von Lampe B, Matthes H, Kaiser A, Riecken EO. Retinoids inhibit adhesion to laminin in human pancreatic carcinoma cells via the alpha 6 beta 1-integrin receptor. Gastroenterology 1997; 112:532-42.
    • (1997) Gastroenterology , vol.112 , pp. 532-542
    • Rosewicz, S.1    Wollbergs, K.2    Von Lampe, B.3    Matthes, H.4    Kaiser, A.5    Riecken, E.O.6
  • 55
    • 0031742047 scopus 로고    scopus 로고
    • Integration of growth factor, extracellular matrix, and retinoid signals during bronchial epithelial cell differentiation
    • Moghal N, Neel BG. Integration of growth factor, extracellular matrix, and retinoid signals during bronchial epithelial cell differentiation. Mol Cell Biol 1998; 18:6666-78.
    • (1998) Mol Cell Biol , vol.18 , pp. 6666-6678
    • Moghal, N.1    Neel, B.G.2
  • 56
    • 0030982282 scopus 로고    scopus 로고
    • Short-chain fatty acid-initiated cell cycle arrest and apoptosis of colonic epithelial cells is linked to mitochondrial function
    • Heerdt BG, Houston MA, Augenlicht LH. Short-chain fatty acid-initiated cell cycle arrest and apoptosis of colonic epithelial cells is linked to mitochondrial function. Cell Growth Differ 1997; 8:523-32.
    • (1997) Cell Growth Differ , vol.8 , pp. 523-532
    • Heerdt, B.G.1    Houston, M.A.2    Augenlicht, L.H.3
  • 57
    • 0030852948 scopus 로고    scopus 로고
    • Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT) reduction
    • Liu Y, Peterson DA, Kimura H, Schubert D. Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction. J Neurochem 1997; 69:581-93.
    • (1997) J Neurochem , vol.69 , pp. 581-593
    • Liu, Y.1    Peterson, D.A.2    Kimura, H.3    Schubert, D.4
  • 58
    • 0031684855 scopus 로고    scopus 로고
    • Extracellular matrix-associated transforming growth factor-$: Role in cancer cell growth and invasion
    • Taipale J, Sharinen J, Keski-Oja J. Extracellular matrix-associated transforming growth factor-$: Role in cancer cell growth and invasion. Adv Cancer Res 1998; 87-134.
    • (1998) Adv Cancer Res , pp. 87-134
    • Taipale, J.1    Sharinen, J.2    Keski-Oja, J.3
  • 59
    • 0030740155 scopus 로고    scopus 로고
    • Amphiregulin antisense oligonucleotide inhibits the growth of T3M4 human pancreatic cancer cells and sensitized the cells to EGF receptor-targeted therapy
    • Fumatomi H, Itakura J, Ishiwata T, et al. Amphiregulin antisense oligonucleotide inhibits the growth of T3M4 human pancreatic cancer cells and sensitized the cells to EGF receptor-targeted therapy. Int J Cancer 1997; 72:512-7.
    • (1997) Int J Cancer , vol.72 , pp. 512-517
    • Fumatomi, H.1    Itakura, J.2    Ishiwata, T.3
  • 60
    • 0345416740 scopus 로고    scopus 로고
    • Amphiregulin but not TGF″ is a functional autocrine growth factor from human pancreatic cancer cells
    • Murphy LO, Adrian TE. Amphiregulin but not TGF″ is a functional autocrine growth factor from human pancreatic cancer cells. Pancreas 1997; 15:447.
    • (1997) Pancreas , vol.15 , pp. 447
    • Murphy, L.O.1    Adrian, T.E.2
  • 61
    • 25144478795 scopus 로고    scopus 로고
    • Decrease in Ki-67 and epidermal growth factor receptor expression correlates with retinoic acid induced growth inhibition in a cervical cancer cell line
    • DiSilvestro P, Flanagan C, Angros L, Benbrook D. Decrease in Ki-67 and epidermal growth factor receptor expression correlates with retinoic acid induced growth inhibition in a cervical cancer cell line. Proc Am Assoc Cancer Res 1997; 38:88.
    • (1997) Proc Am Assoc Cancer Res , vol.38 , pp. 88
    • DiSilvestro, P.1    Flanagan, C.2    Angros, L.3    Benbrook, D.4
  • 62
    • 85008473306 scopus 로고    scopus 로고
    • Retinoid-induced differentiation and apoptosis in breast cancer cells: Effects on c-erbB2 expression and cisplatin sensitivity
    • Grunt T, Dittrich E, Offerdinger M, et al. Retinoid-induced differentiation and apoptosis in breast cancer cells: Effects on c-erbB2 expression and cisplatin sensitivity. Proc Am Assoc Cancer Res 1998; 39:311.
    • (1998) Proc Am Assoc Cancer Res , vol.39 , pp. 311
    • Grunt, T.1    Dittrich, E.2    Offerdinger, M.3
  • 63
    • 0025176042 scopus 로고
    • Ligand-activated thyroid hormone and retinoic acid receptors inhibit growth factor receptor promoter expression
    • Hudson LG, Santon JB, Glass CK, Gill GN. Ligand-activated thyroid hormone and retinoic acid receptors inhibit growth factor receptor promoter expression. Cell 1990; 62:1165-75.
    • (1990) Cell , vol.62 , pp. 1165-1175
    • Hudson, L.G.1    Santon, J.B.2    Glass, C.K.3    Gill, G.N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.