Serum and correspondent tissue measurements of epidermal growth factor (EGF) and epidermal growth factor receptor (EGF-R): Clinical relevance in pancreatic cancer and chronic pancreatitis

International Journal of Pancreatology

Volumn 25, Issue 2, 1999, Pages 89-96

  Birk, Dieter ^a   Gansauge, Frank ^a   Gansauge, Susanne ^a   Formentini, Andrea ^a   Lucht, Andreas ^a   Beger, Hans Guenther ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Chronic pancreatitis; Epidermal growth factor; Epidermal growth factor receptor; Pancreatic cancer; Serum tests; Tumor markers

Indexed keywords

CA 19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR;

ADULT; ARTICLE; CANCER DIAGNOSIS; CHRONIC PANCREATITIS; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SURGICAL PATIENT;

EID: 0033065168     PISSN: 01694197     EISSN: None     Source Type: Journal    
DOI: 10.1385/ijgc:25:2:89     Document Type: Article

References (32)

1. Fallon JH, Seroogy KB, Louglin SE, Morrison RS, Bradshaw RA, Knauer DJ, et al. Epidermal growth factor immuno-reactive material in the central nervous system: Location and development. Science 1984; 224: 1107-1109.
2. Gregory H, Walsh S, Hopkins CR. The identification of urogastrone in serum, saliva and gastric juice. Gastroenterology 1979; 77: 313-318.
3. Costrini NV, Beck R. Epidermal growth factor urogastrone receptors in normal human liver and hepatoma. Cancer 1983; 51: 2191-2196.
4. Marti U. Burwein SJ, Jones AL. The biological effects of eridermal growth factor receptor, with emphasis on the gastrointestinal tract and liver. An update. Hepatology 1989; 9: 126-138.
5. Hollenberg MD. Growth factors, their receptors and development. Am J Med Genet 1989; 24: 35-42.
6. Scheving LA, Scheving LE, Willingham MC, Veseley DL. Epidermal growth factor enhances guanylate cyclase activity in vivo and in vitro. Endocrinology 1985; 116: 332-336.
7. National Cancer Institute. Annual Cancer Statistics Review 1973-1987. Department of Health and Human Services, Bethesda, MD: 1991; NIH publication no. 91-2789.
8. Korc M. Growth factors and pancreatic cancer. Int J Pancreatol 1991; 9: 87-91.
9. Korc M, Chandrrasekar B, Yamananka Y, Friess H, Buechler M. Beger HG. Overexpression of epidermal growth factor receptor in human pancreatic cancer is associated with concomittant increase in the levels of epidermal growth factor and transforming growth factor alpha. J Clin Invest 1992; 90(4): 1352-1360.
10. Korc M. The role of growth factors in pancreatic cancer. Surg Oncol Clin North Am 1998; 7: 25-41.
11. Bleday R, Tzanakakis GN, Schwalke MA, Wanebo HJ, Vezeredis MP. Epidermal growth factor stimulation and metastatic rate in human pancreatic carcinoma cell lines. J Surg Res 1990; 49(3): 276-279.
12. Yamananka Y, Friess H, Kobrin MS, Büchler M, Beger HG, Korc M. Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressivness. Anticancer Res 1993; 13(3); 565-569.
13. Uegaki K, Nio Y, Inonc Y, Minari Y, Sato Y, Song MH, et al. Clinicopathological significance of epidermal growth factors and its receptor in human pancreatic cancer. Anticancer Res 1997; 17(5): 3841-3847.
14. Lemoine NR, Lobresco M, Leung H, Barton C, Hughes CM, Prigent SA. et al. The erbB-3 gene in human pancreatic cancer. J Pathol 1992 (3): 269-273.
15. Baselega J, Norton L, Masui H, Pandiella A, Coplan K, Miller WH, et al. Antitumor effect of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibody. J Natl Cancer Inst 1993; 85(16): 1327-1333.
16. Szepeshazi K, Scally AV, Halmos G, Groot K, Radulovic S. Growth inhibtion of estrogen-dependant and estrogen independant MXT ammary cancers in mice by the bombesin and gastrin releasing peptide antagonist RC-3095. J Natl Cancer Inst 1992; 84(24): 1915-1922.
17. Safi F, Roscher R, Beger HG. Tumor markers in pancreatic cancer. Sensititvity and specificity of CA 19/9. HepatoGastroenterology 1991; 26: 419-423.
18. Niederau C, Grendell JH. Diagnosis of pancreatic carcinoma. Imaging techniques and tumor markers. Pancreas 1992; 7: 66-86.
19. Schölmerich J. Diagnosis of pancreatic cancer, in: Beger HG, Büchler M, Malfertheimer P, eds. Standards in Pancreatic Surgery. Springer Verlag, Berlin 1993: Pp. 578-590.
20. Briese V, Müller H. Fetomaternale signal transduktion dutch wachstumsfaktoren. Zentrbl Gynäkol 1992; 114: 219-223.
21. Hirata Y, Moore GW, Bertagna C. Orth DN. Plasma concentrations of immunorective human epidermal growth factor in man. J Clin Endocrinol Metab 1980; 50: 440-444.
22. Oka Y, Orth DN. Human plasma epidermal growth factor is associated with blood platlets. J Clin Invest 1983; 72: 249-259.
23. Starkey RH, Orth DN. Radioimmunoassay of human epidermal growth factor. J Clin Endocrinol Metab 1977; 45: 1144-1153.
24. Mattila AL, Viininka L, Saario I, Perheentupa J. Human epidermal growth factor receptors in human transitional cell carcinoma. Regul Pept 1988; 23: 89-93.
25. Savage CR, Imamgami T, Cohen S. The primary structure of epidermal growth factor. J Biol Chem 1972; 248: 7669-7672.
26. Savage AP, Chatterjee VK, Gregory H, Bloom SR. Epidermal growth factor in blood. Regul Pept 1986; 16: 199-206.
27. Birk D, Gansauge F, Formentini A, Safi F, Beger HG. Expression of epidermal growth factors and their ligands in experimental pancreatic cancer. Digestion 1995; 52 (6): 312.
28. Konturek SJ, Tasler J, Bielanski W, Cieszkowski M, Pawlik W. Role of liver and intestines in the degradation of epidermal growth factor. Digestion 1990; 45(4): 202-211.
29. Jaworek J, Konturek SJ. Distribution, release and secretory actitvity of epidermal growth factor in the pancreas. Int J Pancreatol 1990; 6(3): 189-205.
30. Konturek JW, Buesing M, Hopt UT, Stachura J, Becker HD, Konturek SJ. Secretion of protein and epidermal growth factor by transplanted human pancreas. Int J Pancreatol 1992; 12(1): 23-29.
31. Skov Olson P. Role of epidermal growth factor in gastroduodenal mucosal protection. J Clin Gastroenterol 1988; (Suppl I),10: 146-148.
32. Dembinski A, Gregory H, Konturek S J, Polanski M. Trophic action of epidermal growth factor on the pancreas and the gastroduodenal mucosa in rats. J Physiol 1982; 325: 35-42.