Role of the hexapeptide disulfide loop in the γ-carboxyglutamic acid domain of protein C in Ca2+-mediated structural and functional properties

Biochemistry

Volumn 44, Issue 37, 2005, Pages 12508-12514

  Dai, Qiuyun ^a   Prorok, Mary ^a   Castellino, Francis J ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CARBOXYLIC ACIDS; IMMUNOLOGY; MOLECULAR STRUCTURE; PROTEINS; VITAMINS;

ANTICOAGULANTS; BLOOD PROTEINS; CIRCULAR DICHROISM; MEMBRANE BINDING;

POLYPEPTIDES;

4 CARBOXYGLUTAMIC ACID; ANTICOAGULANT AGENT; CALCIUM ION; ENDOTHELIAL PROTEIN C RECEPTOR; HEXAPEPTIDE; IMMUNOMODULATING AGENT; PHOSPHOLIPID; PROTEIN C; RECEPTOR PROTEIN; UNCLASSIFIED DRUG; VITAMIN K GROUP;

ALKYLATION; AMINO TERMINAL SEQUENCE; ARTICLE; CALCIUM TRANSPORT; CIRCULAR DICHROISM; DISULFIDE BOND; MEMBRANE BINDING; MEMBRANE VESICLE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION; SURFACE PLASMON RESONANCE; WILD TYPE;

1-CARBOXYGLUTAMIC ACID; AMINO ACID SEQUENCE; BINDING SITES; CALCIUM; CIRCULAR DICHROISM; DISULFIDES; KINETICS; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PROTEIN C; PROTEIN STRUCTURE, SECONDARY; SURFACE PLASMON RESONANCE;

EID: 24944501229     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050974+     Document Type: Article

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