-
1
-
-
0035979192
-
Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
-
S. Bauer, C.J. Kirschning, H. Hacker, V. Redecke, S. Hausmann, S. Akira, H. Wagner, and G.B. Lipford Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition Proc. Natl. Acad. Sci. U.S.A. 98 16 2001 9237 9242
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, Issue.16
, pp. 9237-9242
-
-
Bauer, S.1
Kirschning, C.J.2
Hacker, H.3
Redecke, V.4
Hausmann, S.5
Akira, S.6
Wagner, H.7
Lipford, G.B.8
-
2
-
-
0035871737
-
Bacterial CpG-DNA triggers activation and maturation of human CD11c-, CD123+ dendritic cells
-
M. Bauer, V. Redecke, J.W. Ellwart, B. Scherer, J.P. Kremer, H. Wagner, and G.B. Lipford Bacterial CpG-DNA triggers activation and maturation of human CD11c-, CD123+ dendritic cells J. Immunol. 166 8 2001 5000 5007
-
(2001)
J. Immunol.
, vol.166
, Issue.8
, pp. 5000-5007
-
-
Bauer, M.1
Redecke, V.2
Ellwart, J.W.3
Scherer, B.4
Kremer, J.P.5
Wagner, H.6
Lipford, G.B.7
-
3
-
-
0036453721
-
Evolution of the TIR, tolls and TLRs: Functional inferences from computational biology
-
B. Beutler, and M. Rehli Evolution of the TIR, tolls and TLRs: functional inferences from computational biology Curr. Top. Microbiol. Immunol. 270 2002 1 21
-
(2002)
Curr. Top. Microbiol. Immunol.
, vol.270
, pp. 1-21
-
-
Beutler, B.1
Rehli, M.2
-
4
-
-
0032435640
-
DNA and a CpG oligonucleotide derived from Babesia bovis are mitogenic for bovine B cells
-
W.C. Brown, D.M. Estes, S.E. Chantler, K.A. Kegerreis, and C.E. Suarez DNA and a CpG oligonucleotide derived from Babesia bovis are mitogenic for bovine B cells Infect. Immun. 66 11 1998 5423 5432
-
(1998)
Infect. Immun.
, vol.66
, Issue.11
, pp. 5423-5432
-
-
Brown, W.C.1
Estes, D.M.2
Chantler, S.E.3
Kegerreis, K.A.4
Suarez, C.E.5
-
5
-
-
5044237403
-
New approaches in immunotherapy: Allergen vaccination with immunostimulatory DNA
-
P.S. Creticos, Y.H. Chen, and J.T. Schroeder New approaches in immunotherapy: allergen vaccination with immunostimulatory DNA Immunol. Allergy Clin. N. Am. 24 4 2004 569 581
-
(2004)
Immunol. Allergy Clin. N. Am.
, vol.24
, Issue.4
, pp. 569-581
-
-
Creticos, P.S.1
Chen, Y.H.2
Schroeder, J.T.3
-
6
-
-
0037304594
-
Protection of chickens against Escherichia coli infections by DNA containing CpG motifs
-
S. Gomis, L. Babiuk, D.L. Godson, B. Allan, T. Thrush, H. Townsend, P. Willson, E. Waters, R. Hecker, and A. Potter Protection of chickens against Escherichia coli infections by DNA containing CpG motifs Infect. Immun. 71 2 2003 857 863
-
(2003)
Infect. Immun.
, vol.71
, Issue.2
, pp. 857-863
-
-
Gomis, S.1
Babiuk, L.2
Godson, D.L.3
Allan, B.4
Thrush, T.5
Townsend, H.6
Willson, P.7
Waters, E.8
Hecker, R.9
Potter, A.10
-
7
-
-
0034619794
-
A toll-like receptor recognizes bacterial DNA
-
H. Hemmi, O. Takeuchi, T. Kawai, T. Kaisho, S. Sato, H. Sanjo, M. Matsumoto, K. Hoshino, H. Wagner, K. Takeda, and S. Akira A toll-like receptor recognizes bacterial DNA Nature 408 6813 2000 740 745 (Erratum in Nature 409 (6820) (2001) 646)
-
(2000)
Nature
, vol.408
, Issue.6813
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
8
-
-
0036570169
-
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
-
V. Hornung, S. Rothenfusser, S. Britsch, A. Krug, B. Jahrsdorfer, T. Giese, S. Endres, and G. Hartmann Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides J. Immunol. 168 9 2002 4531 4537
-
(2002)
J. Immunol.
, vol.168
, Issue.9
, pp. 4531-4537
-
-
Hornung, V.1
Rothenfusser, S.2
Britsch, S.3
Krug, A.4
Jahrsdorfer, B.5
Giese, T.6
Endres, S.7
Hartmann, G.8
-
9
-
-
24144492673
-
Safety of CpG oligodeoxynucleotides in veterinary species
-
X.P. Ioannou, P. Griebel, A. Mena, S.M. Gomis, D.L. Godson, G. Mutwiri, R. Hecker, L.A. Babiuk, and S. van Drunen Littel-van den Hurk Safety of CpG oligodeoxynucleotides in veterinary species Antisense Nucleic Acid Drug Dev. 13 2003 157 167
-
(2003)
Antisense Nucleic Acid Drug Dev.
, vol.13
, pp. 157-167
-
-
Ioannou, X.P.1
Griebel, P.2
Mena, A.3
Gomis, S.M.4
Godson, D.L.5
Mutwiri, G.6
Hecker, R.7
Babiuk, L.A.8
Van Drunen Littel-Van Den Hurk, S.9
-
10
-
-
3042548161
-
Use of CpG oligodeoxynucleotides as immunoprotective agents
-
D.M. Klinman Use of CpG oligodeoxynucleotides as immunoprotective agents Expert Opin. Biol. Ther. 4 6 2004 937 946
-
(2004)
Expert Opin. Biol. Ther.
, vol.4
, Issue.6
, pp. 937-946
-
-
Klinman, D.M.1
-
12
-
-
0034933019
-
Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells
-
A. Krug, S. Rothenfusser, V. Hornung, B. Jahrsdorfer, S. Blackwell, Z.K. Ballas, S. Endres, A.M. Krieg, and G. Hartmann Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells Eur. J. Immunol. 31 7 2001 2154 2163
-
(2001)
Eur. J. Immunol.
, vol.31
, Issue.7
, pp. 2154-2163
-
-
Krug, A.1
Rothenfusser, S.2
Hornung, V.3
Jahrsdorfer, B.4
Blackwell, S.5
Ballas, Z.K.6
Endres, S.7
Krieg, A.M.8
Hartmann, G.9
-
13
-
-
0030595339
-
The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
B. Lemaitre, E. Nicolas, L. Michaut, J.M. Reichhart, and J.A. Hoffmann The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults Cell 86 6 1996 973 983
-
(1996)
Cell
, vol.86
, Issue.6
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.M.4
Hoffmann, J.A.5
-
14
-
-
0036086410
-
Recent improvements to the SMART domain-based sequence annotation resource
-
I. Letunic, L. Goodstadt, N.J. Dickens, T. Doerks, J. Schultz, R. Mott, F. Ciccarelli, R.R. Copley, C.P. Ponting, and P. Bork Recent improvements to the SMART domain-based sequence annotation resource Nucleic Acids Res. 30 1 2002 242 244
-
(2002)
Nucleic Acids Res.
, vol.30
, Issue.1
, pp. 242-244
-
-
Letunic, I.1
Goodstadt, L.2
Dickens, N.J.3
Doerks, T.4
Schultz, J.5
Mott, R.6
Ciccarelli, F.7
Copley, R.R.8
Ponting, C.P.9
Bork, P.10
-
15
-
-
0033806950
-
Poly-guanosine motifs costimulate antigen-reactive CD8 T cells while bacterial CpG-DNA affect T-cell activation via antigen-presenting cell-derived cytokines
-
G.B. Lipford, S. Bendigs, K. Heeg, and H. Wagner Poly-guanosine motifs costimulate antigen-reactive CD8 T cells while bacterial CpG-DNA affect T-cell activation via antigen-presenting cell-derived cytokines Immunology 101 1 2000 46 52
-
(2000)
Immunology
, vol.101
, Issue.1
, pp. 46-52
-
-
Lipford, G.B.1
Bendigs, S.2
Heeg, K.3
Wagner, H.4
-
16
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
R. Medzhitov, P. Preston-Hurlburt, and C.A. Janeway Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity Nature 388 6640 1997 394 397
-
(1997)
Nature
, vol.388
, Issue.6640
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
17
-
-
0242557470
-
Bovine and ovine blood mononuclear leukocytes differ markedly in innate immune responses induced by class a and class B CpG-oligodeoxynucleotides
-
A. Mena, A. Nichani, Y. Popowych, X.P. Ioannou, D. Godson, G. Mutwiri, R. Hecker, L.A. Babiuk, and P.J. Griebel Bovine and ovine blood mononuclear leukocytes differ markedly in innate immune responses induced by class A and class B CpG-oligodeoxynucleotides Oligonucleotides 13 2003 245 260
-
(2003)
Oligonucleotides
, vol.13
, pp. 245-260
-
-
Mena, A.1
Nichani, A.2
Popowych, Y.3
Ioannou, X.P.4
Godson, D.5
Mutwiri, G.6
Hecker, R.7
Babiuk, L.A.8
Griebel, P.J.9
-
18
-
-
12244274967
-
Biological activity of immunostimulatory CpG DNA motifs in domestic animals. A review
-
G. Mutwiri, R. Pontarollo, S. Babiuk, P. Griebel, S. van Drunen Littel-van den Hurk, A. Mena, C. Tsang, V. Alcon, A. Nichani, X. Ioannou, S. Gomis, H. Townsend, R. Hecker, A. Potter, and L.A. Babiuk Biological activity of immunostimulatory CpG DNA motifs in domestic animals. A review Vet. Immunol. Immunopathol. 6722 2003 1 15
-
(2003)
Vet. Immunol. Immunopathol.
, vol.6722
, pp. 1-15
-
-
Mutwiri, G.1
Pontarollo, R.2
Babiuk, S.3
Griebel, P.4
Van Drunen Littel-Van Den Hurk, S.5
Mena, A.6
Tsang, C.7
Alcon, V.8
Nichani, A.9
Ioannou, X.10
Gomis, S.11
Townsend, H.12
Hecker, R.13
Potter, A.14
Babiuk, L.A.15
-
19
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
A. Poltorak, X. He, I. Smirnova, M.Y. Liu, C. Van Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, C. Galanos, M. Freudenberg, P. Ricciardi-Castagnoli, B. Layton, and B. Beutler Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene Science 282 5396 1998 2085 2088
-
(1998)
Science
, vol.282
, Issue.5396
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
Freudenberg, M.11
Ricciardi-Castagnoli, P.12
Layton, B.13
Beutler, B.14
-
20
-
-
4344689650
-
Toll-like receptors involved in the response to microbial pathogens: Development of agonists for toll-like receptor 9
-
C. Schetter, and J. Vollmer Toll-like receptors involved in the response to microbial pathogens: development of agonists for toll-like receptor 9 Curr. Opin. Drug Discov. Dev. 7 2 2004 204 210
-
(2004)
Curr. Opin. Drug Discov. Dev.
, vol.7
, Issue.2
, pp. 204-210
-
-
Schetter, C.1
Vollmer, J.2
-
21
-
-
0031867535
-
Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
-
T. Sparwasser, E.S. Koch, R.M. Vabulas, K. Heeg, G.B. Lipford, J.W. Ellwart, and H. Wagner Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells Eur. J. Immunol. 28 6 1998 2045 2054
-
(1998)
Eur. J. Immunol.
, vol.28
, Issue.6
, pp. 2045-2054
-
-
Sparwasser, T.1
Koch, E.S.2
Vabulas, R.M.3
Heeg, K.4
Lipford, G.B.5
Ellwart, J.W.6
Wagner, H.7
-
22
-
-
0030816325
-
Macrophages sense pathogens via DNA motifs: Induction of tumor necrosis factor-alpha-mediated shock
-
T. Sparwasser, T. Miethke, G. Lipford, A. Erdmann, H. Hacker, K. Heeg, and H. Wagner Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock Eur. J. Immunol. 27 7 1997 1671 1679
-
(1997)
Eur. J. Immunol.
, vol.27
, Issue.7
, pp. 1671-1679
-
-
Sparwasser, T.1
Miethke, T.2
Lipford, G.3
Erdmann, A.4
Hacker, H.5
Heeg, K.6
Wagner, H.7
-
23
-
-
0035865054
-
Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs
-
D. Verthelyi, K.J. Ishii, M. Gursel, F. Takeshita, and D.M. Klinman Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs J. Immunol. 166 4 2001 2372 2377
-
(2001)
J. Immunol.
, vol.166
, Issue.4
, pp. 2372-2377
-
-
Verthelyi, D.1
Ishii, K.J.2
Gursel, M.3
Takeshita, F.4
Klinman, D.M.5
-
24
-
-
2942679083
-
The immunobiology of the TLR9 subfamily
-
H. Wagner The immunobiology of the TLR9 subfamily Trends Immunol. 25 7 2004 381 386
-
(2004)
Trends Immunol.
, vol.25
, Issue.7
, pp. 381-386
-
-
Wagner, H.1
-
25
-
-
0347126491
-
Differential production of cytokines, reactive oxygen and nitrogen by bovine macrophages and dendritic cells stimulated with Toll-like receptor agonists
-
D. Werling, J.C. Hope, C.J. Howard, and T.W. Jungi Differential production of cytokines, reactive oxygen and nitrogen by bovine macrophages and dendritic cells stimulated with Toll-like receptor agonists Immunology 111 1 2004 41 52
-
(2004)
Immunology
, vol.111
, Issue.1
, pp. 41-52
-
-
Werling, D.1
Hope, J.C.2
Howard, C.J.3
Jungi, T.W.4
-
26
-
-
0742287262
-
CpG DNA and cancer immunotherapy: Orchestrating the antitumor immune response
-
J.E. Wooldridge, and G.J. Weiner CpG DNA and cancer immunotherapy: orchestrating the antitumor immune response Curr. Opin. Oncol. 15 6 2003 440 445
-
(2003)
Curr. Opin. Oncol.
, vol.15
, Issue.6
, pp. 440-445
-
-
Wooldridge, J.E.1
Weiner, G.J.2
-
27
-
-
0035174859
-
Induction of interleukin-6 and interleukin-12 in bovine B lymphocytes, monocytes and macrophages by a CpG oligodeoxynucleotides (ODN 2059) containing the GTCGTT motif
-
Y. Zhang, L.K. Shoda, K.A. Brayton, D.M. Estes, G.H. Palmer, and W.C. Brown Induction of interleukin-6 and interleukin-12 in bovine B lymphocytes, monocytes and macrophages by a CpG oligodeoxynucleotides (ODN 2059) containing the GTCGTT motif J. Interferon Cytokine Res. 21 10 2001 871 881
-
(2001)
J. Interferon Cytokine Res.
, vol.21
, Issue.10
, pp. 871-881
-
-
Zhang, Y.1
Shoda, L.K.2
Brayton, K.A.3
Estes, D.M.4
Palmer, G.H.5
Brown, W.C.6
-
28
-
-
1542377424
-
A toll-like receptor that prevents infection by uropathogenic bacteria
-
D. Zhang, G. Zhang, M.S. Hayden, M.B. Greenblatt, C. Bussey, R.A. Flavell, and S. Ghosh A toll-like receptor that prevents infection by uropathogenic bacteria Science 303 5663 2004 1522 1526
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1522-1526
-
-
Zhang, D.1
Zhang, G.2
Hayden, M.S.3
Greenblatt, M.B.4
Bussey, C.5
Flavell, R.A.6
Ghosh, S.7
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