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Volumn 30, Issue 3, 2005, Pages 213-227

Identification of oxidative stress-related proteins for predictive screening of hepatotoxicity using a proteomic approach

Author keywords

Biomarker; Glutathione peroxidase; Oxidative stress; Peroxiredoxin; Proteomics; Rat hepatocyte

Indexed keywords

AMIODARONE; BIOLOGICAL MARKER; GLUTATHIONE PEROXIDASE; PARACETAMOL; PEROXIREDOXIN; TETRACYCLINE;

EID: 24944469203     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.30.213     Document Type: Article
Times cited : (49)

References (54)
  • 1
    • 0024432862 scopus 로고
    • A role for the glutathione peroxidase/reductase enzyme system in the protection from paracetamol toxicity in isolated mouse hepatocyte
    • Adamson, G.M. and Harman, A.W. (1989): A role for the glutathione peroxidase/reductase enzyme system in the protection from paracetamol toxicity in isolated mouse hepatocyte. Biochem. Pharmacol., 38, 3323-3330.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 3323-3330
    • Adamson, G.M.1    Harman, A.W.2
  • 3
    • 1542437234 scopus 로고    scopus 로고
    • Expression pattern and regulation of heme oxygenase-1/heat shock protein 32 in human liver cells
    • Bauer, I., Rensing, H., Florax, A., Ulrich, C., Pistorius, G., Redl, H. and Bauer, M. (2003): Expression pattern and regulation of heme oxygenase-1/heat shock protein 32 in human liver cells. Shock., 20, 116-122.
    • (2003) Shock , vol.20 , pp. 116-122
    • Bauer, I.1    Rensing, H.2    Florax, A.3    Ulrich, C.4    Pistorius, G.5    Redl, H.6    Bauer, M.7
  • 4
    • 0038172423 scopus 로고    scopus 로고
    • Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: Possible implications for toxicogenomics use of in vitro systems
    • Boess, F., Kamber, M., Romer, S., Gasser, R., Muller, D., Albertini, S. and Suter, L. (2003): Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: Possible implications for toxicogenomics use of in vitro systems. Toxicol. Sci., 73, 386-402.
    • (2003) Toxicol. Sci. , vol.73 , pp. 386-402
    • Boess, F.1    Kamber, M.2    Romer, S.3    Gasser, R.4    Muller, D.5    Albertini, S.6    Suter, L.7
  • 5
    • 0016828072 scopus 로고
    • Fatty liver induced by tetracycline in the rat. Dose-response relationships and effect of sex
    • Breen, K.J., Schenker, S. and Heimberg, M. (1975): Fatty liver induced by tetracycline in the rat. Dose-response relationships and effect of sex. Gastroenterology, 69, 714-723.
    • (1975) Gastroenterology , vol.69 , pp. 714-723
    • Breen, K.J.1    Schenker, S.2    Heimberg, M.3
  • 6
    • 0033639131 scopus 로고    scopus 로고
    • A strategy for primary high throughput cytotoxicity screening in pharmaceutical toxicology
    • Bugelski, P.J., Atif, U., Molton, S., Toeg, I., Lord, P.G. and Morgan, D.G. (2000): A strategy for primary high throughput cytotoxicity screening in pharmaceutical toxicology. Pharm. Res., 17, 1265-1272.
    • (2000) Pharm. Res. , vol.17 , pp. 1265-1272
    • Bugelski, P.J.1    Atif, U.2    Molton, S.3    Toeg, I.4    Lord, P.G.5    Morgan, D.G.6
  • 7
    • 0021957080 scopus 로고
    • Electron microscopic demonstration of lysosomal inclusion bodies in lung, liver, lymph nodes and blood leucocytes of patients with amiodarone pulmonary toxicity
    • Dake, M.D., Madison, J.N., Manatogomery, C.K., Shellitoo, J.E., Hinchcliffe, W.A., Winkler, M.L. and Baindton, D.F. (1985): Electron microscopic demonstration of lysosomal inclusion bodies in lung, liver, lymph nodes and blood leucocytes of patients with amiodarone pulmonary toxicity. Am. J. Med., 78, 506-512.
    • (1985) Am. J. Med. , vol.78 , pp. 506-512
    • Dake, M.D.1    Madison, J.N.2    Manatogomery, C.K.3    Shellitoo, J.E.4    Hinchcliffe, W.A.5    Winkler, M.L.6    Baindton, D.F.7
  • 8
    • 0024549203 scopus 로고
    • Investigation into the mechanism of tetracycline-induced steatosis: Study in isolated hepatocytes
    • Deboyser, D., Goethals, F., Krack, G. and Roberfroid, M. (1989): Investigation into the mechanism of tetracycline-induced steatosis: Study in isolated hepatocytes. Toxicol. Appl. Pharmacol., 97, 473-479.
    • (1989) Toxicol. Appl. Pharmacol. , vol.97 , pp. 473-479
    • Deboyser, D.1    Goethals, F.2    Krack, G.3    Roberfroid, M.4
  • 11
    • 0025144041 scopus 로고
    • Correlation of acute lethal potency with in vitro cytotoxicity
    • Fry, J.P., Garle, M.J., Hammond, A.H. and Hatfield, A. (1990): Correlation of acute lethal potency with in vitro cytotoxicity. Toxicol. In Vitro. 4, 175-178.
    • (1990) Toxicol. In Vitro , vol.4 , pp. 175-178
    • Fry, J.P.1    Garle, M.J.2    Hammond, A.H.3    Hatfield, A.4
  • 12
    • 0032844918 scopus 로고    scopus 로고
    • Down regulation of superoxide dismutases and glutathione peroxidase by reactive oxygen and nitrogen species
    • Fujii, J. and Taniguchi, N. (1999): Down regulation of superoxide dismutases and glutathione peroxidase by reactive oxygen and nitrogen species. Free Rad. Res., 31, 301-308.
    • (1999) Free Rad. Res. , vol.31 , pp. 301-308
    • Fujii, J.1    Taniguchi, N.2
  • 13
    • 0003130095 scopus 로고
    • Statistics for toxicologists
    • (Hayes, A.W., ed.), 3rd ed., Raven Press, New York
    • Gad, S.C. and Weil, C.S. (1994): Statistics for toxicologists. In Principles and Methods of Toxicology (Hayes, A.W., ed.), 3rd ed., pp. 221-274, Raven Press, New York.
    • (1994) Principles and Methods of Toxicology , pp. 221-274
    • Gad, S.C.1    Weil, C.S.2
  • 14
    • 0037333902 scopus 로고    scopus 로고
    • Toxicogenomics of bromobenzene hepatotoxicity: A combined transcriptomics and proteomics approach
    • Heijne, W.H.M, Stierum, R.H., Slijper, M., van Bladeren, P.J. and van Ommen, B. (2003): Toxicogenomics of bromobenzene hepatotoxicity: A combined transcriptomics and proteomics approach. Biochem. Pharmacol., 65, 857-875.
    • (2003) Biochem. Pharmacol. , vol.65 , pp. 857-875
    • Heijne, W.H.M.1    Stierum, R.H.2    Slijper, M.3    Van Bladeren, P.J.4    Van Ommen, B.5
  • 17
    • 0021346560 scopus 로고
    • Cytotoxic effects of N-acetyl-p-benzoquinone imine, a common arylating intermediate of paracetamol and N-hydroxy-paracetamol
    • Holme, J.A., Dahlin, D.C., Nelson, S.D. and Dybing, E. (1984): Cytotoxic effects of N-acetyl-p-benzoquinone imine, a common arylating intermediate of paracetamol and N-hydroxy-paracetamol. Biochem. Pharmacol., 33, 401-406.
    • (1984) Biochem. Pharmacol. , vol.33 , pp. 401-406
    • Holme, J.A.1    Dahlin, D.C.2    Nelson, S.D.3    Dybing, E.4
  • 18
    • 0027458724 scopus 로고
    • Cellular accumulation of amiodarone and desethylamiodarone in cultured human cells. Consequences of drug accumulation on cellular lipid metabolism and plasma membrane properties of chronically exposed cells
    • Honegger, U.E., Zuehlke, R.D., Scuntaro, I., Schaefer, M.H., Toplak, H. and Wiesmann, U.N. (1993): Cellular accumulation of amiodarone and desethylamiodarone in cultured human cells. Consequences of drug accumulation on cellular lipid metabolism and plasma membrane properties of chronically exposed cells. Biochem. Pharmacol., 45, 349-356.
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 349-356
    • Honegger, U.E.1    Zuehlke, R.D.2    Scuntaro, I.3    Schaefer, M.H.4    Toplak, H.5    Wiesmann, U.N.6
  • 20
    • 0028818098 scopus 로고
    • Expression of the mRNA of heme-binding protein 23 is coordinated with that of heme oxigenase-1 by heme and heavy metals in primary rat hepatocytes and hepatoma cells
    • Immenschuh, S., Iwahara, S., Satoh, H., Nell, C., Katz, N. and Muller-Eberhard, U. (1995): Expression of the mRNA of heme-binding protein 23 is coordinated with that of heme oxigenase-1 by heme and heavy metals in primary rat hepatocytes and hepatoma cells. Biochemistry, 34, 13407-13411.
    • (1995) Biochemistry , vol.34 , pp. 13407-13411
    • Immenschuh, S.1    Iwahara, S.2    Satoh, H.3    Nell, C.4    Katz, N.5    Muller-Eberhard, U.6
  • 21
    • 0344862115 scopus 로고    scopus 로고
    • Differential cellular and subcellular localization of heme-binding protein 23/peroxiredoxin I and heme oxygenase-1 in rat liver
    • Immenschuh, S., Baumgart-Vogt, E., Tan, M., Iwahara, S., Ramadori, G. and Fahimi, H.D. (2003): Differential cellular and subcellular localization of heme-binding protein 23/peroxiredoxin I and heme oxygenase-1 in rat liver. J. Histochem. Cytochem., 51, 1621-1631.
    • (2003) J. Histochem. Cytochem. , vol.51 , pp. 1621-1631
    • Immenschuh, S.1    Baumgart-Vogt, E.2    Tan, M.3    Iwahara, S.4    Ramadori, G.5    Fahimi, H.D.6
  • 22
    • 0041881584 scopus 로고    scopus 로고
    • Assessment of hepatocytes and liver slices as in vitro test systems to predict in vivo gene expression
    • Jessen, B.A., Mullins, J.S., Peyster, A., and Stevens, G.J. (2003): Assessment of hepatocytes and liver slices as in vitro test systems to predict in vivo gene expression. Toxicol. Sci., 75, 208-222.
    • (2003) Toxicol. Sci. , vol.75 , pp. 208-222
    • Jessen, B.A.1    Mullins, J.S.2    Peyster, A.3    Stevens, G.J.4
  • 23
    • 1842295744 scopus 로고    scopus 로고
    • Regulatory role for a novel human thioredoxin peroxidase in NF-κB activation
    • Jin, D.Y., Chae, H.Z., Rhee, S.G. and Jeang, K.T. (1997): Regulatory role for a novel human thioredoxin peroxidase in NF-κB activation. J. Biol. Chem., 272, 30952-30961.
    • (1997) J. Biol. Chem. , vol.272 , pp. 30952-30961
    • Jin, D.Y.1    Chae, H.Z.2    Rhee, S.G.3    Jeang, K.T.4
  • 24
    • 0141746553 scopus 로고    scopus 로고
    • Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-α
    • Kang, S.W., Chae, H.Z., Seo, M.S., Kim, K., Baines, I.C. and Rhee, S.G. (1998): Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-α. J. Biol. Chem., 273, 6297-6302.
    • (1998) J. Biol. Chem. , vol.273 , pp. 6297-6302
    • Kang, S.W.1    Chae, H.Z.2    Seo, M.S.3    Kim, K.4    Baines, I.C.5    Rhee, S.G.6
  • 25
    • 0033580846 scopus 로고    scopus 로고
    • Aldolase mediates the association of F-actin with the insulin-responsive glucose transport GLUT4
    • Kao, A.W., Noda, Y., Johnson, J.H., Pessin, J.E. and Saltiel, A.R. (1999): Aldolase mediates the association of F-actin with the insulin-responsive glucose transport GLUT4. J. Biol. Chem., 274, 17742-17747.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17742-17747
    • Kao, A.W.1    Noda, Y.2    Johnson, J.H.3    Pessin, J.E.4    Saltiel, A.R.5
  • 26
    • 0023196435 scopus 로고
    • Effect of amiodarone on serum lipids, lipoprotein lipase, and hepatic triglyceride lipase
    • Kasim, S.E., Bagchi, N., Brown, T.R. and Khilnani, S. (1987): Effect of amiodarone on serum lipids, lipoprotein lipase, and hepatic triglyceride lipase. Endocrinol., 120, 1997-1995.
    • (1987) Endocrinol. , vol.120 , pp. 1997-1995
    • Kasim, S.E.1    Bagchi, N.2    Brown, T.R.3    Khilnani, S.4
  • 28
    • 15744398882 scopus 로고    scopus 로고
    • Investigation of a hepatotoxicity screening system in primary cell cultures - "What biomarkers would need to be addressed to estimate toxicity in conventional and new approaches?"
    • Kikkawa, R., Yamamoto, T., Fukushima, T., Yamada, H. and Horii, I. (2005): Investigation of a hepatotoxicity screening system in primary cell cultures - "What biomarkers would need to be addressed to estimate toxicity in conventional and new approaches?" -. J. Toxicol. Sci., 30, 61-72.
    • (2005) J. Toxicol. Sci. , vol.30 , pp. 61-72
    • Kikkawa, R.1    Yamamoto, T.2    Fukushima, T.3    Yamada, H.4    Horii, I.5
  • 29
    • 0020325093 scopus 로고
    • Amino acid transport in isolated rat hepatocytes
    • Kilberge, M.S. (1982): Amino acid transport in isolated rat hepatocytes. J. Membr. Biol., 69, 1-12.
    • (1982) J. Membr. Biol. , vol.69 , pp. 1-12
    • Kilberge, M.S.1
  • 32
    • 0034832007 scopus 로고    scopus 로고
    • Evaluation of the use of in vitro methodologies as tools for screening new compounds for potentials in vivo toxicity
    • Luber-Narod, J., Smith, B., Grant, W., Jimeno, J.M., Lopea-Lazaro, L. and Faircloth, G.T. (2001): Evaluation of the use of in vitro methodologies as tools for screening new compounds for potentials in vivo toxicity. Toxicol. In Vitro, 15, 571-577.
    • (2001) Toxicol. In Vitro , vol.15 , pp. 571-577
    • Luber-Narod, J.1    Smith, B.2    Grant, W.3    Jimeno, J.M.4    Lopea-Lazaro, L.5    Faircloth, G.T.6
  • 34
    • 0037044804 scopus 로고    scopus 로고
    • Pag, a putative tumor suppressor, interacts with the Myc box II domain of c-Myc and selectively alters its biological function and target gene expression
    • Mu, Z.M., Yin, X.Y. and Prochownik, E.V. (2002): Pag, a putative tumor suppressor, interacts with the Myc box II domain of c-Myc and selectively alters its biological function and target gene expression. J. Biol. Chem., 277, 43175-43184.
    • (2002) J. Biol. Chem. , vol.277 , pp. 43175-43184
    • Mu, Z.M.1    Yin, X.Y.2    Prochownik, E.V.3
  • 36
    • 0034693445 scopus 로고    scopus 로고
    • Co-induction of heme oxygenase-1 and Peroxiredoxin I in astrocytes and microglia around hemorrhagic region in rat brain
    • Nakaso, K., Kitayama, M., Mizuta, E., Fukuda, H., Ishii, T., Nakashima, K. and Yamada, K. (2000): Co-induction of heme oxygenase-1 and Peroxiredoxin I in astrocytes and microglia around hemorrhagic region in rat brain. Neurosci. Lett., 293, 49-52.
    • (2000) Neurosci. Lett. , vol.293 , pp. 49-52
    • Nakaso, K.1    Kitayama, M.2    Mizuta, E.3    Fukuda, H.4    Ishii, T.5    Nakashima, K.6    Yamada, K.7
  • 37
    • 0025694879 scopus 로고
    • Molecular mechanisms of the hepatotoxicity caused by acetaminophen
    • Nelson, S.D. (1990): Molecular mechanisms of the hepatotoxicity caused by acetaminophen. Semin. Liver Disease, 10, 267-278.
    • (1990) Semin. Liver Disease , vol.10 , pp. 267-278
    • Nelson, S.D.1
  • 39
    • 0027503487 scopus 로고
    • Identification of an actin binding region in aldolase
    • O'Reilly, G. and Clarke, F. (1993): Identification of an actin binding region in aldolase. FEBS Lett., 321, 69-72.
    • (1993) FEBS Lett. , vol.321 , pp. 69-72
    • O'Reilly, G.1    Clarke, F.2
  • 40
    • 0032816930 scopus 로고    scopus 로고
    • Use of primary cultures of rat hepatocytes to predict toxicity in the early development of new chemical entities
    • Paillard, F., Finot, F., Mouche, I., Prenez, A. and Vericat, J.A. (1999): Use of primary cultures of rat hepatocytes to predict toxicity in the early development of new chemical entities. Toxicol. In Vitro, 13, 693-700.
    • (1999) Toxicol. In Vitro , vol.13 , pp. 693-700
    • Paillard, F.1    Finot, F.2    Mouche, I.3    Prenez, A.4    Vericat, J.A.5
  • 42
    • 0037205455 scopus 로고    scopus 로고
    • Proteomics analysis of cellular response to oxidative stress. Evidence for in vitro overoxidation of peroxiredoxins at their active site
    • Rabilloud, T., Heller, M., Gasnier, F., Luche, S., Rey, C., Aebersold, R., Benahmed, M., Louisot, P. and Lunardi, J. (2002): Proteomics analysis of cellular response to oxidative stress. Evidence for in vitro overoxidation of peroxiredoxins at their active site. J. Biol. Chem., 277, 19396-19401.
    • (2002) J. Biol. Chem. , vol.277 , pp. 19396-19401
    • Rabilloud, T.1    Heller, M.2    Gasnier, F.3    Luche, S.4    Rey, C.5    Aebersold, R.6    Benahmed, M.7    Louisot, P.8    Lunardi, J.9
  • 43
    • 0033380284 scopus 로고    scopus 로고
    • A hepatotoxic dose of acetaminophen modulates expression of BCL-2, BCL-X(L), and BCL-X(S) during apoptotic and necrotic death of mouse liver cells in vivo
    • Ray, S.D. and Jena, N. (2000): A hepatotoxic dose of acetaminophen modulates expression of BCL-2, BCL-X(L), and BCL-X(S) during apoptotic and necrotic death of mouse liver cells in vivo. Arch. Toxicol., 73, 594-606.
    • (2000) Arch. Toxicol. , vol.73 , pp. 594-606
    • Ray, S.D.1    Jena, N.2
  • 44
    • 0030434801 scopus 로고    scopus 로고
    • Protection of acetaminophen-induced hepatocellular apoptosis and necrosis by cholesteryl hemisuccinate pretreatment
    • Ray, S.D., Mumaw, V., Raje, R.R. and Fariss, M.W. (1996): Protection of acetaminophen-induced hepatocellular apoptosis and necrosis by cholesteryl hemisuccinate pretreatment. J. Pharmacol. Exp. Ther., 279, 1470-1483.
    • (1996) J. Pharmacol. Exp. Ther. , vol.279 , pp. 1470-1483
    • Ray, S.D.1    Mumaw, V.2    Raje, R.R.3    Fariss, M.W.4
  • 45
    • 0036147966 scopus 로고    scopus 로고
    • Genomics and proteomics analysis of acetaminophen toxicity in mouse liver
    • Ruepp, S.U., Tonge, R.P., Shaw, J., Wallis, N. and Pognan, F. (2002): Genomics and proteomics analysis of acetaminophen toxicity in mouse liver. Toxicol. Sci., 65, 135-150.
    • (2002) Toxicol. Sci. , vol.65 , pp. 135-150
    • Ruepp, S.U.1    Tonge, R.P.2    Shaw, J.3    Wallis, N.4    Pognan, F.5
  • 46
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen, P.O. (1976): Preparation of isolated rat liver cells. Methods Cell Biol., 13, 29-38.
    • (1976) Methods Cell Biol. , vol.13 , pp. 29-38
    • Seglen, P.O.1
  • 49
    • 0036692549 scopus 로고    scopus 로고
    • Advantages of in vitro cytotoxicity testing by using primary rat hepatocytes in comparison with established cell lines
    • Wang, K., Shindo, H., Inoue, T. and Horii, I. (2002): Advantages of in vitro cytotoxicity testing by using primary rat hepatocytes in comparison with established cell lines. J. Toxicol. Sci., 27, 229-237.
    • (2002) J. Toxicol. Sci. , vol.27 , pp. 229-237
    • Wang, K.1    Shindo, H.2    Inoue, T.3    Horii, I.4
  • 50
    • 0030803669 scopus 로고    scopus 로고
    • The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity
    • Wen, S.T. and Van Etten, R.A. (1997): The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity. Genes Dev., 11, 2456-2467.
    • (1997) Genes Dev. , vol.11 , pp. 2456-2467
    • Wen, S.T.1    Van Etten, R.A.2
  • 51
    • 0028954158 scopus 로고
    • Two-dimensional electrophoretic mapping of hepatic and renal stress proteins
    • Witzmann, F., Clack, J., Fulz, C. and Jarnot, B. (1995): Two-dimensional electrophoretic mapping of hepatic and renal stress proteins. Electrophoresis, 16, 451-459.
    • (1995) Electrophoresis , vol.16 , pp. 451-459
    • Witzmann, F.1    Clack, J.2    Fulz, C.3    Jarnot, B.4
  • 52
    • 0029443871 scopus 로고
    • Comparative 2D-electrophoretic mapping of human and rodent hepatic stress proteins as potential biomarkers
    • Witzmann, F.A., Fulz, C. and Lipscomb, J. (1995): Comparative 2D-electrophoretic mapping of human and rodent hepatic stress proteins as potential biomarkers. Applied and Theoretical Electrophoresis, 5, 113-117.
    • (1995) Applied and Theoretical Electrophoresis , vol.5 , pp. 113-117
    • Witzmann, F.A.1    Fulz, C.2    Lipscomb, J.3
  • 53
    • 0030049530 scopus 로고    scopus 로고
    • Toxicant-induced alterations in two-dimensional electrophoresis patterns of hepatic and renal stress proteins
    • Witzmann, F.A., Fulz, C.D. and Lipscomb, J.C. (1996): Toxicant-induced alterations in two-dimensional electrophoresis patterns of hepatic and renal stress proteins. Electrophoresis, 17, 198-202.
    • (1996) Electrophoresis , vol.17 , pp. 198-202
    • Witzmann, F.A.1    Fulz, C.D.2    Lipscomb, J.C.3
  • 54
    • 0030692005 scopus 로고    scopus 로고
    • Thioredoxin peroxidase is a novel inhibitor of apoptosis with a mechanism distinct from that of Bcl-2
    • Zhang, P., Liu, B., Kang, S.W., Seo, M.S., Rhee, S.G. and Obeid, L.M. (1997): Thioredoxin peroxidase is a novel inhibitor of apoptosis with a mechanism distinct from that of Bcl-2. J. Biol. Chem., 272, 30615-30618.
    • (1997) J. Biol. Chem. , vol.272 , pp. 30615-30618
    • Zhang, P.1    Liu, B.2    Kang, S.W.3    Seo, M.S.4    Rhee, S.G.5    Obeid, L.M.6


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