-
1
-
-
0037041183
-
5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition
-
Auberson YP, Allgeier H, Bischoff S, Lingenhoehl K, Moretti R, Schmutz M (2002) 5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition. Bioorg Med Chem Lett 12:1099-1102
-
(2002)
Bioorg Med Chem Lett
, vol.12
, pp. 1099-1102
-
-
Auberson, Y.P.1
Allgeier, H.2
Bischoff, S.3
Lingenhoehl, K.4
Moretti, R.5
Schmutz, M.6
-
2
-
-
0025134730
-
Activation of NMDA receptor-coupled channels suppresses the inhibitory action of adenosine on hippocampal slices
-
Bartrup JT, Stone TW (1990) Activation of NMDA receptor-coupled channels suppresses the inhibitory action of adenosine on hippocampal slices. Brain Res 530:330-334
-
(1990)
Brain Res
, vol.530
, pp. 330-334
-
-
Bartrup, J.T.1
Stone, T.W.2
-
3
-
-
0034812072
-
The use of constitutively active receptors for drug discovery at the G protein-coupled receptor gene pool
-
Behan DP, Chalmers DT (2001) The use of constitutively active receptors for drug discovery at the G protein-coupled receptor gene pool. Curr Opin Drug Discov Dev 4:548-560
-
(2001)
Curr Opin Drug Discov Dev
, vol.4
, pp. 548-560
-
-
Behan, D.P.1
Chalmers, D.T.2
-
4
-
-
0023691731
-
Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics
-
Bialojan C, Takai A (1988) Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics. Biochem J 25:283-290
-
(1988)
Biochem J
, vol.25
, pp. 283-290
-
-
Bialojan, C.1
Takai, A.2
-
5
-
-
0027476024
-
A synaptic model of memory: Long-term potentiation in the hippocampus
-
Bliss TV, Collingridge GL (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361:31-39
-
(1993)
Nature
, vol.361
, pp. 31-39
-
-
Bliss, T.V.1
Collingridge, G.L.2
-
6
-
-
0025721797
-
Heterogeneity of NMDA receptors regulating the release of dopamine and acetylcholine from striatal slices
-
Cai N, Kiss B, Erdo L (1991) Heterogeneity of NMDA receptors regulating the release of dopamine and acetylcholine from striatal slices. J Neurochem 57:2148-2151
-
(1991)
J Neurochem
, vol.57
, pp. 2148-2151
-
-
Cai, N.1
Kiss, B.2
Erdo, L.3
-
7
-
-
0032971311
-
Subtype-specific enhancement of NMDA receptor currents by mutant huntingtin
-
Chen NS, Luo T, Wellington C, Metzler M, McCutcheon K, Hayden MR, Raymond LA (1999) Subtype-specific enhancement of NMDA receptor currents by mutant huntingtin. J Neurochem 72:1890-1898
-
(1999)
J Neurochem
, vol.72
, pp. 1890-1898
-
-
Chen, N.S.1
Luo, T.2
Wellington, C.3
Metzler, M.4
McCutcheon, K.5
Hayden, M.R.6
Raymond, L.A.7
-
8
-
-
0032748413
-
Emergence of excitotoxicity in cultured forebrain neurons coincides with larger glutamate-stimulated [Ca(2+)](i) increases and NMDA receptor mRNA levels
-
Cheng C, Fass DM, Reynolds IJ (1999) Emergence of excitotoxicity in cultured forebrain neurons coincides with larger glutamate-stimulated [Ca(2+)](i) increases and NMDA receptor mRNA levels. Brain Res 849:97-108
-
(1999)
Brain Res
, vol.849
, pp. 97-108
-
-
Cheng, C.1
Fass, D.M.2
Reynolds, I.J.3
-
9
-
-
0035577313
-
NMDA receptor antagonists as analgesics: Focus on the NR2B subtype
-
Chizh BA, Headley PM, Tzschentke TM (2001) NMDA receptor antagonists as analgesics: focus on the NR2B subtype. Trends Pharmacol Sci 22:636-642
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 636-642
-
-
Chizh, B.A.1
Headley, P.M.2
Tzschentke, T.M.3
-
10
-
-
0029917198
-
Pentameric subunit stoichiometry of a neuronal glutamate receptor
-
Ferrer-Montiel AV, Montal M (1996) Pentameric subunit stoichiometry of a neuronal glutamate receptor. Proc Natl Acad Sci USA 93:2741-2744
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2741-2744
-
-
Ferrer-Montiel, A.V.1
Montal, M.2
-
11
-
-
0025038394
-
Presynaptic NMDA receptors stimulate noradrenaline release in the cerebral cortex
-
Fink K, Bonisch H, Gothert M (1990). Presynaptic NMDA receptors stimulate noradrenaline release in the cerebral cortex. Eur J Pharmacol 185:115-117
-
(1990)
Eur J Pharmacol
, vol.185
, pp. 115-117
-
-
Fink, K.1
Bonisch, H.2
Gothert, M.3
-
12
-
-
0031443289
-
Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro
-
Fischer G, Mutel V, Trube G, Malherbe P, Kew JN, Mohacsi E, Heitz MP, Kemp JA (1997) Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro. J Pharmacol Exp Ther 283:1285-1292
-
(1997)
J Pharmacol Exp Ther
, vol.283
, pp. 1285-1292
-
-
Fischer, G.1
Mutel, V.2
Trube, G.3
Malherbe, P.4
Kew, J.N.5
Mohacsi, E.6
Heitz, M.P.7
Kemp, J.A.8
-
13
-
-
0033914752
-
Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: Effects of schizophrenia
-
Gao XM, Sakai K, Roberts RC, Conley RR, Dean B, Tamminga CA (2000) Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. Am J Psychiat 157:1141-1149
-
(2000)
Am J Psychiat
, vol.157
, pp. 1141-1149
-
-
Gao, X.M.1
Sakai, K.2
Roberts, R.C.3
Conley, R.R.4
Dean, B.5
Tamminga, C.A.6
-
14
-
-
0036720776
-
Pharmacological characterization of Ro 63-1908 (1-[2-(4-hydroxy-phenoxy)- ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol), a novel subtype-selective N-methyl-D-aspartate antagonist
-
Gill R, Alanine A, Bourson A, Buttelmann B, Fischer G, Heitz MP, Kew JN, Level Trafit B, Lorez HP, Malherbe P, Miss MT, Mutel V, Pinard E, Roever S, Schmitt M, Trube G, Wybrecht R, Wyler R, Kemp JA (2002) Pharmacological characterization of Ro 63-1908 (1-[2-(4-hydroxy-phenoxy)-ethyl]-4-(4-methyl- benzyl)-piperidin-4-ol), a novel subtype-selective N-methyl-D-aspartate antagonist. J Pharmacol Exp Ther 302:940-948
-
(2002)
J Pharmacol Exp Ther
, vol.302
, pp. 940-948
-
-
Gill, R.1
Alanine, A.2
Bourson, A.3
Buttelmann, B.4
Fischer, G.5
Heitz, M.P.6
Kew, J.N.7
Level Trafit, B.8
Lorez, H.P.9
Malherbe, P.10
Miss, M.T.11
Mutel, V.12
Pinard, E.13
Roever, S.14
Schmitt, M.15
Trube, G.16
Wybrecht, R.17
Wyler, R.18
Kemp, J.A.19
-
15
-
-
0014198715
-
Inhibitors of protein biosynthesis. II. Mode of action of anisomycin
-
Grollman AP (1967) Inhibitors of protein biosynthesis. II. Mode of action of anisomycin. J Biol Chem 242:3226-3233
-
(1967)
J Biol Chem
, vol.242
, pp. 3226-3233
-
-
Grollman, A.P.1
-
17
-
-
0030593920
-
The contribution of adenosine to paired-pulse inhibition in the normal and disinhibited hippocampal slice
-
Higgins MJ, Stone TW (1996) The contribution of adenosine to paired-pulse inhibition in the normal and disinhibited hippocampal slice. Eur J Pharmacol 317:215-223
-
(1996)
Eur J Pharmacol
, vol.317
, pp. 215-223
-
-
Higgins, M.J.1
Stone, T.W.2
-
18
-
-
0012107261
-
Distinct NMDA receptor subpopulations contribute to long-term potentiation and long-term depression induction
-
Hrabetova S, Serrano P, Blace N, Tse HW, Skifter DA, Jane DE, Monaghan DT, Sacktor TC (2000) Distinct NMDA receptor subpopulations contribute to long-term potentiation and long-term depression induction. J Neurosci 20:RC81
-
(2000)
J Neurosci
, vol.20
-
-
Hrabetova, S.1
Serrano, P.2
Blace, N.3
Tse, H.W.4
Skifter, D.A.5
Jane, D.E.6
Monaghan, D.T.7
Sacktor, T.C.8
-
19
-
-
0032971347
-
Modulation of long-term potentiation in the hippocampus by NMDA-mediated presynaptic inhibition
-
Kato K, Zorumski CF (1999) Modulation of long-term potentiation in the hippocampus by NMDA-mediated presynaptic inhibition. Neuroscience 92:1261-1272
-
(1999)
Neuroscience
, vol.92
, pp. 1261-1272
-
-
Kato, K.1
Zorumski, C.F.2
-
20
-
-
0030450983
-
A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones
-
Kew JNC, Trube G, Kemp JA (1996) A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones. J Physiol 497:761-772
-
(1996)
J Physiol
, vol.497
, pp. 761-772
-
-
Kew, J.N.C.1
Trube, G.2
Kemp, J.A.3
-
21
-
-
0030991790
-
Molecular determinants of agonist discrimination by NMDA receptor subunits: Analysis of the glutamate binding site on the NR2B subunit
-
Laube B, Hirai H, Sturgess M, Betz H, Kuhse J (1997) Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit. Neuron 18:493-503
-
(1997)
Neuron
, vol.18
, pp. 493-503
-
-
Laube, B.1
Hirai, H.2
Sturgess, M.3
Betz, H.4
Kuhse, J.5
-
22
-
-
0032523002
-
Evidence for a tetrameric structure of recombinant NMDA receptors
-
Laube B, Kuhse J, Betz H (1998) Evidence for a tetrameric structure of recombinant NMDA receptors. J Neurosci 18:2954-2961
-
(1998)
J Neurosci
, vol.18
, pp. 2954-2961
-
-
Laube, B.1
Kuhse, J.2
Betz, H.3
-
23
-
-
2342637165
-
Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity
-
Liu LD, Wong TP, Pozza MF, Lingenhoehl K, Wang YS, Sheng M, Auberson YP, Wang YT (2004) Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity. Science 304:1021-1024
-
(2004)
Science
, vol.304
, pp. 1021-1024
-
-
Liu, L.D.1
Wong, T.P.2
Pozza, M.F.3
Lingenhoehl, K.4
Wang, Y.S.5
Sheng, M.6
Auberson, Y.P.7
Wang, Y.T.8
-
24
-
-
0035970522
-
Pharmacological characterization of interactions of RO25-6981 with the NR2B ([epsilon]2) subunit
-
Lynch DR, Shim SS, Seifert KM, Kurapathi S, Mutel V, Gallagher MJ, Guttmann RP (2001) Pharmacological characterization of interactions of RO25-6981 with the NR2B ([epsilon]2) subunit. Eur J Pharmacol 416:185-195
-
(2001)
Eur J Pharmacol
, vol.416
, pp. 185-195
-
-
Lynch, D.R.1
Shim, S.S.2
Seifert, K.M.3
Kurapathi, S.4
Mutel, V.5
Gallagher, M.J.6
Guttmann, R.P.7
-
25
-
-
0032567729
-
A tetrameric subunit stoichiometry for a glutamate receptor-channel complex
-
Mano I, Teichberg VI (1998) A tetrameric subunit stoichiometry for a glutamate receptor-channel complex. Neuroreport 9:327-331
-
(1998)
Neuroreport
, vol.9
, pp. 327-331
-
-
Mano, I.1
Teichberg, V.I.2
-
26
-
-
0025818997
-
Autoreceptor regulation of glutamate and aspartate release from slices of the hippocampal CA1 area
-
Martin D, Bustos GA, Bowe MA, Bray SD, Nadler JV (1991) Autoreceptor regulation of glutamate and aspartate release from slices of the hippocampal CA1 area. J Neurochem 56:1647-1655
-
(1991)
J Neurochem
, vol.56
, pp. 1647-1655
-
-
Martin, D.1
Bustos, G.A.2
Bowe, M.A.3
Bray, S.D.4
Nadler, J.V.5
-
27
-
-
0031969962
-
In vitro binding properties in rat brain of [3H]Ro25-6981, a potent and selective antagonist of NMDA receptors containing NR2B subunits
-
Mutel V, Buchy D, Klingelschmidt A, Messer J, Bleuel Z, Kemp JA, Richards JG (1998) In vitro binding properties in rat brain of [3H]Ro25-6981, a potent and selective antagonist of NMDA receptors containing NR2B subunits. J Neurochem 70:2147-2155
-
(1998)
J Neurochem
, vol.70
, pp. 2147-2155
-
-
Mutel, V.1
Buchy, D.2
Klingelschmidt, A.3
Messer, J.4
Bleuel, Z.5
Kemp, J.A.6
Richards, J.G.7
-
28
-
-
0035823205
-
Suppression of presynaptic responses to adenosine by activation of NMDA receptors
-
Nikbakht MR, Stone TW (2001) Suppression of presynaptic responses to adenosine by activation of NMDA receptors. Eur J Pharmacol 427:13-25
-
(2001)
Eur J Pharmacol
, vol.427
, pp. 13-25
-
-
Nikbakht, M.R.1
Stone, T.W.2
-
29
-
-
0025893284
-
NMDA increases the excitability of nigrostriatal dopamine terminals
-
Overton P, Clark D (1991) NMDA increases the excitability of nigrostriatal dopamine terminals. Eur J Pharmacol 201:117-120
-
(1991)
Eur J Pharmacol
, vol.201
, pp. 117-120
-
-
Overton, P.1
Clark, D.2
-
30
-
-
0030722469
-
Stoichiometry of recombinant N-methyl-D-aspartate receptor channels inferred from single-channel current patterns
-
Premkumar LS, Auerbach A (1997) Stoichiometry of recombinant N-methyl-D-aspartate receptor channels inferred from single-channel current patterns. J Gen Physiol 110:485-502
-
(1997)
J Gen Physiol
, vol.110
, pp. 485-502
-
-
Premkumar, L.S.1
Auerbach, A.2
-
31
-
-
0035214464
-
Agonism, inverse agonism, and neutral antagonism at the constitutively active human neurotensin receptor 2
-
Richard F, Barroso S, Martinez J, Labbe Jullie C, Kitabgi P (2001) Agonism, inverse agonism, and neutral antagonism at the constitutively active human neurotensin receptor 2. Mol Pharmacol 60:1392-1398
-
(2001)
Mol Pharmacol
, vol.60
, pp. 1392-1398
-
-
Richard, F.1
Barroso, S.2
Martinez, J.3
Labbe Jullie, C.4
Kitabgi, P.5
-
32
-
-
0032486422
-
The tetrameric structure of a glutamate receptor channel
-
Rosenmund C, Stern-Bach Y, Stevens CF (1998) The tetrameric structure of a glutamate receptor channel. Science 280:1596-1599
-
(1998)
Science
, vol.280
, pp. 1596-1599
-
-
Rosenmund, C.1
Stern-Bach, Y.2
Stevens, C.F.3
-
33
-
-
5444268839
-
Comment on the role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity
-
Rusakov DA, Scimemi A, Walker MC, Kullmann DM (2004) Comment on the role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity. Science 305:1912b
-
(2004)
Science
, vol.305
-
-
Rusakov, D.A.1
Scimemi, A.2
Walker, M.C.3
Kullmann, D.M.4
-
34
-
-
0037109755
-
Direct effects of calmodulin on NMDA receptor single-channel gating in rat hippocampal granule cells
-
Rycroft BK, Gibb AJ (2002) Direct effects of calmodulin on NMDA receptor single-channel gating in rat hippocampal granule cells. J Neurosci 22:8860-8868
-
(2002)
J Neurosci
, vol.22
, pp. 8860-8868
-
-
Rycroft, B.K.1
Gibb, A.J.2
-
35
-
-
0031029841
-
Constitutively active G protein-coupled receptors: Potential mechanisms of receptor activation
-
Scheer A, Cotecchia S (1997) Constitutively active G protein-coupled receptors: potential mechanisms of receptor activation. J Recept Signal Tr R 17:57-73
-
(1997)
J Recept Signal Tr R
, vol.17
, pp. 57-73
-
-
Scheer, A.1
Cotecchia, S.2
-
36
-
-
0029060722
-
Hypoxia, excitotoxicity, and neuroprotection in the hippocampal slice preparation
-
Schurr A, Payne RS, Heine MF, Rigor BM (1995) Hypoxia, excitotoxicity, and neuroprotection in the hippocampal slice preparation. J Neurosci Meth 59:129-138
-
(1995)
J Neurosci Meth
, vol.59
, pp. 129-138
-
-
Schurr, A.1
Payne, R.S.2
Heine, M.F.3
Rigor, B.M.4
-
37
-
-
0037362019
-
Interactions between adenosine and metabotropic receptors in the rat hippocampal slice
-
Shahraki A, Stone TW (2003) Interactions between adenosine and metabotropic receptors in the rat hippocampal slice. Brit J Pharmacol 138:1059-1068
-
(2003)
Brit J Pharmacol
, vol.138
, pp. 1059-1068
-
-
Shahraki, A.1
Stone, T.W.2
-
38
-
-
0034067617
-
Antiparkinsonian actions of CP-101,606, an antagonist of NR2B subunit-containing N-methyl-D-aspartate receptors
-
Steece-Collier K, Chambers LK, Jaw-Tsai S S, Menniti FS, Greenamyre JT (2000) Antiparkinsonian actions of CP-101,606, an antagonist of NR2B subunit-containing N-methyl-D-aspartate receptors. Exp Neurol 163:239-243
-
(2000)
Exp Neurol
, vol.163
, pp. 239-243
-
-
Steece-Collier, K.1
Chambers, L.K.2
Jaw-Tsai, S.S.3
Menniti, F.S.4
Greenamyre, J.T.5
-
39
-
-
0028201307
-
Paired-pulse depression in cultured hippocampal neurons is due to a presynaptic mechanism independent of GABA-B autoreceptor activation
-
Wilcox KS, Dichter MA (1994) Paired-pulse depression in cultured hippocampal neurons is due to a presynaptic mechanism independent of GABA-B autoreceptor activation. J Neurosci 14:1775-1788
-
(1994)
J Neurosci
, vol.14
, pp. 1775-1788
-
-
Wilcox, K.S.1
Dichter, M.A.2
-
40
-
-
33947325187
-
Response to comment on the role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity
-
Wong TP, Liu LD, Sheng M, Wang YT (2004) Response to comment on the role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity. Science 305:1912c
-
(2004)
Science
, vol.305
-
-
Wong, T.P.1
Liu, L.D.2
Sheng, M.3
Wang, Y.T.4
-
41
-
-
0034786559
-
NR2B-containing NMDA autoreceptors at synapses on entorhinal cortical neurons
-
Woodhall G, Evans DI, Cunningham MO, Jones RS (2001) NR2B-containing NMDA autoreceptors at synapses on entorhinal cortical neurons. J Neurophysiol 86:1644-1651
-
(2001)
J Neurophysiol
, vol.86
, pp. 1644-1651
-
-
Woodhall, G.1
Evans, D.I.2
Cunningham, M.O.3
Jones, R.S.4
-
42
-
-
0028040045
-
2+ is increased during normal synaptic transmission and paired-pulse facilitation but not long-term potentiation in area CA1 of hippocampus
-
2+ is increased during normal synaptic transmission and paired-pulse facilitation but not long-term potentiation in area CA1 of hippocampus. J Neurosci 14:645-654
-
(1994)
J Neurosci
, vol.14
, pp. 645-654
-
-
Wu, L.G.1
Saggau, P.2
-
43
-
-
1842290343
-
Transient global ischemia alters NMDA receptor expression in rat hippocampus: Correlation with decreased immunoreactive protein levels of the NR2A/2B subunits, and an altered NMDA receptor functionality
-
Zhang L, Hsu JC, Takagi N, Gurd JW, Wallace MC, Eubanks JH (1997) Transient global ischemia alters NMDA receptor expression in rat hippocampus: correlation with decreased immunoreactive protein levels of the NR2A/2B subunits, and an altered NMDA receptor functionality. J Neurochem 69:1983-1994
-
(1997)
J Neurochem
, vol.69
, pp. 1983-1994
-
-
Zhang, L.1
Hsu, J.C.2
Takagi, N.3
Gurd, J.W.4
Wallace, M.C.5
Eubanks, J.H.6
|