Substrate ambiguity and crystal structure of Pyrococcus furiosus 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase: An ancestral 3-deoxyald-2-ulosonate-phosphate synthase?

Biochemistry

Volumn 44, Issue 36, 2005, Pages 11950-11962

  Schofield, Linley R ^a   Anderson, Bryan F ^a   Patchett, Mark L ^a   Norris, Gillian E ^a   Jameson, Geoffrey B ^a   Parker, Emily J ^a  

^a MASSEY UNIVERSITY   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CARBON; CATALYSIS; CRYSTAL STRUCTURE; DIMERIZATION; ENZYMES; PHOSPHORUS; PROTEINS;

HYPERTHERMOPHILE; MONOSACCHARIDE; PHOSPHOENOLPYRUVATE (PEP); TETRAMERIZATION;

PHOSPHATES;

2 DEHYDRO 3 DEOXYPHOSPHOHEPTONATE ALDOLASE; 2 DEOXY DEXTRO ERYTHROSE 4 PHOSPHATE; 2 DEOXY DEXTRO RIBOSE 5 PHOSPHATE; 3 DEOXY DEXTRO MANNOOCTULOSONATE 8 PHOSPHATE; 3 DEOXY MANNO OCTULOSONIC ACID; 3 DEOXYALD 2 ULOSONATE PHOSPHATE SYNTHASE; AROMATIC AMINO ACID; DEXTRO ARABINOSE 5 PHOSPHATE; DEXTRO ERYTHROSE 4 PHOSPHATE; DEXTRO RIBOSE 5 PHOSPHATE; GLUCOSE 6 PHOSPHATE; GLYCERALDEHYDE 3 PHOSPHATE; METAL ION; MONOSACCHARIDE; OLIGOMER; RECOMBINANT ENZYME; SUGAR PHOSPHATE; SYNTHETASE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CATALYSIS; CATALYST; CRYSTAL; DIMERIZATION; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PYROCOCCUS FURIOSUS; STRUCTURE ANALYSIS;

3-DEOXY-7-PHOSPHOHEPTULONATE SYNTHASE; ALDEHYDE-LYASES; AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PYROCOCCUS FURIOSUS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

ARCHAEA; PYROCOCCUS FURIOSUS;

EID: 24644471426     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050577z     Document Type: Article

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