메뉴 건너뛰기




Volumn 172, Issue 11, 2004, Pages 6790-6802

Characterization of the human Ig heavy chain antigen binding complementarity determining region 3 using a newly developed software algorithm, JOINSOLVER

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; SERINE;

EID: 2442717677     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.11.6790     Document Type: Article
Times cited : (110)

References (55)
  • 5
    • 0034635335 scopus 로고    scopus 로고
    • Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides
    • Knappik, A., L. Ge, A. Honegger, P. Pack, M. Fischer, G. Wellnhofer, A. Hoess, J. Wolle, A. Pluckthun, and B. Virnekas. 2000. Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides. J. Mol. Biol. 296:57.
    • (2000) J. Mol. Biol. , vol.296 , pp. 57
    • Knappik, A.1    Ge, L.2    Honegger, A.3    Pack, P.4    Fischer, M.5    Wellnhofer, G.6    Hoess, A.7    Wolle, J.8    Pluckthun, A.9    Virnekas, B.10
  • 6
    • 0035166917 scopus 로고    scopus 로고
    • IMGT, the international ImMunoGeneTics database
    • Lefranc, M. P. 2001. IMGT, the international ImMunoGeneTics database. Nucleic Acids Res. 29:207.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 207
    • Lefranc, M.P.1
  • 9
    • 0036252871 scopus 로고    scopus 로고
    • Receptor revision and systemic lupus
    • Monestier, M., and M. Zouali. 2002. Receptor revision and systemic lupus. Scand. J. Immunol. 55:425.
    • (2002) Scand. J. Immunol. , vol.55 , pp. 425
    • Monestier, M.1    Zouali, M.2
  • 12
    • 0034667899 scopus 로고    scopus 로고
    • Heavy chain revision in MRL mice: A potential mechanism for the development of autoreactive B cell precursors
    • Klonowski, K. D., and M. Monestier. 2000. Heavy chain revision in MRL mice: a potential mechanism for the development of autoreactive B cell precursors. J. Immunol. 165:4487.
    • (2000) J. Immunol. , vol.165 , pp. 4487
    • Klonowski, K.D.1    Monestier, M.2
  • 14
    • 0024400179 scopus 로고
    • Novel rearrangements at the immunoglobulin D locus: Inversions and fusions add to IgH somatic diversity
    • Meek, K. D., C. A. Hasemann, and J. D. Capra. 1989. Novel rearrangements at the immunoglobulin D locus: inversions and fusions add to IgH somatic diversity. J. Exp. Med. 170:39.
    • (1989) J. Exp. Med. , vol.170 , pp. 39
    • Meek, K.D.1    Hasemann, C.A.2    Capra, J.D.3
  • 15
    • 0028343694 scopus 로고
    • Molecular characterization of human Ig heavy chain DIR genes
    • Sanz, I., S. S. Wang, G. Meneses, and M. Fischbach. 1994. Molecular characterization of human Ig heavy chain DIR genes. J. Immunol. 152:3958.
    • (1994) J. Immunol. , vol.152 , pp. 3958
    • Sanz, I.1    Wang, S.S.2    Meneses, G.3    Fischbach, M.4
  • 16
    • 0032539691 scopus 로고    scopus 로고
    • -/- mice carrying a human Ig heavy chain transgenic minilocus
    • -/- mice carrying a human Ig heavy chain transgenic minilocus. Proc. Natl. Acad Sci. USA 95:1703.
    • (1998) Proc. Natl. Acad Sci. USA , vol.95 , pp. 1703
    • Tuaillon, N.1    Capra, J.D.2
  • 18
    • 0027087077 scopus 로고
    • Molecular analysis of V(D)J recombination
    • Gellert, M. 1992. Molecular analysis of V(D)J recombination. Annu. Rev. Genet. 26:425.
    • (1992) Annu. Rev. Genet. , vol.26 , pp. 425
    • Gellert, M.1
  • 20
    • 0031586221 scopus 로고    scopus 로고
    • Sequence of the human immunoglobulin diversity (D) segment locus: A systematic analysis provides no evidence for the use of DIR segments, inverted D segments, "minor" D segments or D-D recombination
    • Corbett, S. J., I. M. Tomlinson, E. L. Sonnhammer, D. Buck, and G. Winter. 1997. Sequence of the human immunoglobulin diversity (D) segment locus: a systematic analysis provides no evidence for the use of DIR segments, inverted D segments, "minor" D segments or D-D recombination. J. Mol. Biol. 270:587.
    • (1997) J. Mol. Biol. , vol.270 , pp. 587
    • Corbett, S.J.1    Tomlinson, I.M.2    Sonnhammer, E.L.3    Buck, D.4    Winter, G.5
  • 21
    • 0035893035 scopus 로고    scopus 로고
    • Unusual germline DSP2 gene accounts for all apparent V-D-D-J rearrangements in newborn, but not adult, MRL mice
    • Kompfner, E., P. Oliveira, A. Montalbano, and A. J. Feeney. 2001. Unusual germline DSP2 gene accounts for all apparent V-D-D-J rearrangements in newborn, but not adult, MRL mice. J. Immunol. 167:6933.
    • (2001) J. Immunol. , vol.167 , pp. 6933
    • Kompfner, E.1    Oliveira, P.2    Montalbano, A.3    Feeney, A.J.4
  • 22
    • 0029063311 scopus 로고
    • Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction
    • Brezinschek, H. P., R. I. Brezinschek, and P. E. Lipsky. 1995. Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction. J. Immunol. 155:190.
    • (1995) J. Immunol. , vol.155 , pp. 190
    • Brezinschek, H.P.1    Brezinschek, R.I.2    Lipsky, P.E.3
  • 24
    • 0034901232 scopus 로고    scopus 로고
    • Comparative characteristics of μ chain and α chain transcripts expressed by individual tonsil plasma cells
    • Yavuz, S., A. C. Grammer, A. S. Yavuz, T. Nanki, and P. E. Lipsky. 2001. Comparative characteristics of μ chain and α chain transcripts expressed by individual tonsil plasma cells. Mol. Immunol. 38:19.
    • (2001) Mol. Immunol. , vol.38 , pp. 19
    • Yavuz, S.1    Grammer, A.C.2    Yavuz, A.S.3    Nanki, T.4    Lipsky, P.E.5
  • 27
    • 0023278330 scopus 로고
    • Canonical structures for the hypervariable regions of immunoglobulins
    • Chothia, C., and A. M. Lesk. 1987. Canonical structures for the hypervariable regions of immunoglobulins. J. Mol. Biol. 196:901.
    • (1987) J. Mol. Biol. , vol.196 , pp. 901
    • Chothia, C.1    Lesk, A.M.2
  • 28
    • 0023053742 scopus 로고
    • Phosphocholine binding immunoglobulin Fab McPC603: An x-ray diffraction study at 2.7 A
    • Satow, Y., G. H. Cohen, E. A. Padlan, and D. R. Davies. 1986. Phosphocholine binding immunoglobulin Fab McPC603: an x-ray diffraction study at 2.7 A. J. Mol. Biol. 190:593.
    • (1986) J. Mol. Biol. , vol.190 , pp. 593
    • Satow, Y.1    Cohen, G.H.2    Padlan, E.A.3    Davies, D.R.4
  • 29
    • 0025282239 scopus 로고
    • Organization of variable region segments of the human immunoglobulin heavy chain: Duplication of the D5 cluster within the locus and interchromosomal translocation of variable region segments
    • Matsuda, F., E. K. Shin, Y. Hirabayashi, H. Nagaoka, M. C. Yoshida, S. Q. Zong, and T. Honjo. 1990. Organization of variable region segments of the human immunoglobulin heavy chain: duplication of the D5 cluster within the locus and interchromosomal translocation of variable region segments. EMBO J. 9:2501.
    • (1990) EMBO J. , vol.9 , pp. 2501
    • Matsuda, F.1    Shin, E.K.2    Hirabayashi, Y.3    Nagaoka, H.4    Yoshida, M.C.5    Zong, S.Q.6    Honjo, T.7
  • 31
    • 0023880918 scopus 로고
    • Human immunoglobulin D segments: Isolation of a new D segment and polymorphic deletion of the D1 segment
    • Zong, S. Q., S. Nakai, F. Matsuda, K. H. Lee, and T. Honjo. 1988. Human immunoglobulin D segments: isolation of a new D segment and polymorphic deletion of the D1 segment. Immunol. Lett. 17:329.
    • (1988) Immunol. Lett. , vol.17 , pp. 329
    • Zong, S.Q.1    Nakai, S.2    Matsuda, F.3    Lee, K.H.4    Honjo, T.5
  • 34
    • 0036284914 scopus 로고    scopus 로고
    • The κ gene repertoire of human neonatal B cells
    • Girschick, H. J., and P. E. Lipsky. 2002. The κ gene repertoire of human neonatal B cells. Mol. Immunol. 38:1113.
    • (2002) Mol. Immunol. , vol.38 , pp. 1113
    • Girschick, H.J.1    Lipsky, P.E.2
  • 35
    • 0029655319 scopus 로고    scopus 로고
    • Mechanistic constraints on diversity in human V(D)J recombination
    • Gauss, G. H., and M. R. Lieber. 1996. Mechanistic constraints on diversity in human V(D)J recombination. Mol. Cell. Biol. 16:258.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 258
    • Gauss, G.H.1    Lieber, M.R.2
  • 36
    • 0027159113 scopus 로고
    • H gene segments and CDR3 distribution in the expressed Cα and Cγ repertoires
    • H gene segments and CDR3 distribution in the expressed Cα and Cγ repertoires. J. Immunol. 150:1348.
    • (1993) J. Immunol. , vol.150 , pp. 1348
    • Mortari, F.1    Wang, J.Y.2    Schroeder Jr., H.W.3
  • 37
    • 0028931875 scopus 로고
    • Recombination potential of the human DIR elements
    • Moore, B. B., and K. Meek. 1995. Recombination potential of the human DIR elements. J. Immunol. 154:2175.
    • (1995) J. Immunol. , vol.154 , pp. 2175
    • Moore, B.B.1    Meek, K.2
  • 38
    • 0035997348 scopus 로고    scopus 로고
    • V(D)J recombination: RAG proteins, repair factors, and regulation
    • Gellert, M. 2002. V(D)J recombination: RAG proteins, repair factors, and regulation. Annu. Rev. Biochem. 71:101.
    • (2002) Annu. Rev. Biochem. , vol.71 , pp. 101
    • Gellert, M.1
  • 39
    • 0020041687 scopus 로고
    • Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments
    • Kurosawa, Y., and S. Tonegawa. 1982. Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments. J. Exp. Med. 155:201.
    • (1982) J. Exp. Med. , vol.155 , pp. 201
    • Kurosawa, Y.1    Tonegawa, S.2
  • 40
    • 0026099589 scopus 로고
    • Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes
    • Yamada, M., R. Wasserman, B. A. Reichard, S. Shane, A. J. Caton, and G. Roveta. 1991. Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes. J. Exp. Med. 173:395.
    • (1991) J. Exp. Med. , vol.173 , pp. 395
    • Yamada, M.1    Wasserman, R.2    Reichard, B.A.3    Shane, S.4    Caton, A.J.5    Roveta, G.6
  • 42
    • 0346103724 scopus 로고    scopus 로고
    • Partitioning of rearranged Ig genes by mutation analysis demonstrates D-D fusion and V gene replacement in the expressed human repertoire
    • Collins, A. M., M. Ikutani, D. Puiu, G. A. Buck, A. Nadkarni, and B. Gaeta. 2004. Partitioning of rearranged Ig genes by mutation analysis demonstrates D-D fusion and V gene replacement in the expressed human repertoire. J. Immunol. 172:340.
    • (2004) J. Immunol. , vol.172 , pp. 340
    • Collins, A.M.1    Ikutani, M.2    Puiu, D.3    Buck, G.A.4    Nadkarni, A.5    Gaeta, B.6
  • 43
    • 0024293529 scopus 로고
    • Organization of human immunoglobulin heavy chain diversity gene loci
    • Ichihara, Y., H. Matsuoka, and Y. Kurosawa. 1988. Organization of human immunoglobulin heavy chain diversity gene loci. EMBO J. 7:4141.
    • (1988) EMBO J. , vol.7 , pp. 4141
    • Ichihara, Y.1    Matsuoka, H.2    Kurosawa, Y.3
  • 44
    • 0026069154 scopus 로고
    • Development of hydrophobicity parameters to analyze proteins which bear post- or cotranslational modifications
    • Black, S. D., and D. R. Mould. 1991. Development of hydrophobicity parameters to analyze proteins which bear post- or cotranslational modifications. Anal. Biochem. 193:72.
    • (1991) Anal. Biochem. , vol.193 , pp. 72
    • Black, S.D.1    Mould, D.R.2
  • 45
    • 0020475449 scopus 로고
    • A simple method for displaying the hydropathic character of a protein
    • Kyte, J., and R. F. Doolittle. 1982. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157:105.
    • (1982) J. Mol. Biol. , vol.157 , pp. 105
    • Kyte, J.1    Doolittle, R.F.2
  • 46
    • 0020623947 scopus 로고
    • A computer program for predicting protein antigenic determinants
    • Hopp, T. P., and K. R. Woods. 1983. A computer program for predicting protein antigenic determinants. Mol. Immunol. 20:483.
    • (1983) Mol. Immunol. , vol.20 , pp. 483
    • Hopp, T.P.1    Woods, K.R.2
  • 47
    • 0346364657 scopus 로고    scopus 로고
    • Amino acid properties and consequences of substitutions
    • M. R. Barnes and I. C. Gray. eds. Wiley, Hoboken
    • Betts, M. J., and Russell, R. B. 2003. Amino acid properties and consequences of substitutions. In Bioinformatics for Geneticists, 1st Ed. M. R. Barnes and I. C. Gray. eds. Wiley, Hoboken.
    • (2003) Bioinformatics for Geneticists, 1st Ed.
    • Betts, M.J.1    Russell, R.B.2
  • 49
    • 0034541166 scopus 로고    scopus 로고
    • The VλJ lambda repertoire in human fetal spleen: Evidence for positive selection and extensive receptor editing
    • Lee, J., N. L. Monson, and P. E. Lipsky. 2000. The VλJ lambda repertoire in human fetal spleen: evidence for positive selection and extensive receptor editing. J. Immunol. 165:6322.
    • (2000) J. Immunol. , vol.165 , pp. 6322
    • Lee, J.1    Monson, N.L.2    Lipsky, P.E.3
  • 50
    • 0029065295 scopus 로고
    • Coding end processing is similar throughout ontogeny
    • Nadel, B., S. Tehranchi, and A. J. Feeney. 1995. Coding end processing is similar throughout ontogeny. J. Immunol. 154:6430.
    • (1995) J. Immunol. , vol.154 , pp. 6430
    • Nadel, B.1    Tehranchi, S.2    Feeney, A.J.3
  • 51
    • 0028961228 scopus 로고
    • Coding sequence composition flanking either signal element alters V(D)J recombination efficiency
    • Boubnov, N. V., Z. P. Wills, and D. T. Weaver. 1995. Coding sequence composition flanking either signal element alters V(D)J recombination efficiency. Nucleic Acids Res. 23:1060.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 1060
    • Boubnov, N.V.1    Wills, Z.P.2    Weaver, D.T.3
  • 52
    • 0037155703 scopus 로고    scopus 로고
    • Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
    • Ma, Y., U. Pannicke, K. Schwarz, and M. R. Lieber. 2002. Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell 108:781.
    • (2002) Cell , vol.108 , pp. 781
    • Ma, Y.1    Pannicke, U.2    Schwarz, K.3    Lieber, M.R.4
  • 53
    • 0034612307 scopus 로고    scopus 로고
    • A mechanistic basis for Mre11-directed DNA joining at microhomologies
    • Paull, T. T., and M. Gellert. 2000. A mechanistic basis for Mre11-directed DNA joining at microhomologies. Proc. Natl. Acad. Sci. USA 97:6409.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6409
    • Paull, T.T.1    Gellert, M.2
  • 54
    • 0031974686 scopus 로고    scopus 로고
    • V(D)J recombination activity in human hematopoietic cells: Correlation with developmental stage and genome stability
    • Gauss, G. H., I. Domain, C. L. Hsieh, and M. R. Lieber. 1998. V(D)J recombination activity in human hematopoietic cells: correlation with developmental stage and genome stability. Eur. J. Immunol. 28:351.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 351
    • Gauss, G.H.1    Domain, I.2    Hsieh, C.L.3    Lieber, M.R.4
  • 55
    • 0034927895 scopus 로고    scopus 로고
    • Ig heavy-chain gene revision: Leaping towards autoimmunity
    • Klonowski, K. D., and M. Monestier. 2001. Ig heavy-chain gene revision: leaping towards autoimmunity. Trends Immunol. 22:400.
    • (2001) Trends Immunol. , vol.22 , pp. 400
    • Klonowski, K.D.1    Monestier, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.