Promotion of peptide antimicrobial activity by fatty acid conjugation

Bioconjugate Chemistry

Volumn 15, Issue 3, 2004, Pages 530-535

  Chu Kung, Alexander F ^a   Bozzelli, Kristen N ^a   Lockwood, Nathan A ^b   Haseman, Judith R ^c   Mayo, Kevin H ^c   Tirrell, Matthew V ^a  

^a University of California   (United States)

^b University of Minnesota   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMICROBIAL AGENTS; CYTOLOGY; DICHROISM; FATTY ACIDS; MICROORGANISMS;

ANTI-BACTERIAL ACTIVITY; ANTI-MICROBIAL ACTIVITY; BACTERIAL MEMBRANES; CIRCULAR DICHROISM SPECTRUMS; EUKARYOTIC CELL TOXICITY; HELICAL CONTENT; HEMOLYTIC ACTIVITY; LAURIC ACID; PHOSPHATIDYL CHOLINE; SECONDARY STRUCTURES;

PEPTIDES;

FATTY ACID; LAURIC ACID; LYSYLLEUCYLPHENYLALANYLLYSYLARGINYLHISTIDYLLEUCYLLYSYLTRYPTOPHYLLYSYLISOLEU CYLISOLEUCINE; PEPTIDE AKK; PEPTIDE KAK; PEPTIDE SC4; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLGLYCEROL; POLYPEPTIDE ANTIBIOTIC AGENT; TYROSYLGLYCYLALANYLALANYLLYSYLLYSYLALANYLALANYLLYSYLALANYLALANYLLYSYLLYSYLA LANYLALANYLLYSYSLALANYLALANINE; TYROSYLGLYCYLALANYLLYSYLALANYLLYSYLALANYLALANYLLYSYLALANYLALANYLLYSYLALANYL LYSYLALANYLALANYLLYSYLALANINE; UNCLASSIFIED DRUG;

ALPHA HELIX; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; CIRCULAR DICHROISM; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; ERYTHROCYTE; EUKARYOTIC CELL; HEMOLYSIS; HUMAN; HUMAN CELL; LIPID VESICLE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTEIN SECONDARY STRUCTURE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

BACTERIA (MICROORGANISMS); EUKARYOTA;

EID: 2442715478     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc0341573     Document Type: Article

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