Active site-independent recognition of substrates and product by bovine prothrombinase: A fluorescence resonance energy transfer study

Journal of Biological Chemistry

Volumn 279, Issue 20, 2004, Pages 20786-20793

  Boskovic, Danilo S ^a   Troxler, Thomas ^a   Krishnaswamy, Sriram ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOLOGICAL MEMBRANES; ENZYME KINETICS; FLUORESCENCE; MACROMOLECULES; SUBSTRATES;

BINDING AFFINITY; FLUORESENCE RESONANCE ENERGY TRANSFER; KINETIC STUDIES; PROTHROMBINASE;

ENZYMES;

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5A; EOSIN; KETONE; MEIZOTHROMBIN; PEPTIDE CHLOROMETHYL KETONE; PRETHROMBIN 2; PROTHROMBIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CATTLE; COMPETITIVE INHIBITION; DERIVATIZATION; DISSOCIATION CONSTANT; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBSTRATE; FLUORESCENCE RESONANCE ENERGY TRANSFER; MACROMOLECULE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; REACTION ANALYSIS; SPECTROFLUOROMETRY;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CATTLE; FACTOR VA; FACTOR XA; FLUORESCENCE RESONANCE ENERGY TRANSFER; KINETICS; PROTEIN BINDING; PROTHROMBIN; SUBSTRATE SPECIFICITY; THROMBOPLASTIN;

BOS TAURUS; BOVINAE;

EID: 2442688975     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M400469200     Document Type: Article

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