Kinetics and metabolism of chloral hydrate in children: Identification of dichloroacetate as a metabolite

Biochemical and Biophysical Research Communications

Volumn 235, Issue 3, 1997, Pages 695-698

  Henderson, George N ^a   Yan, Zimeng ^a   James, Margaret O ^b   Davydova, Natalia ^a   Stacpoole, Peter W ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAL HYDRATE; DICHLOROACETIC ACID;

ADOLESCENT; ADULT; ARTICLE; CHILD; DRUG METABOLISM; HUMAN; KINETICS; METABOLITE; PLASMA CLEARANCE; PRIORITY JOURNAL;

EID: 0031587942     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1997.6868     Document Type: Article

References (28)

1. Liebreich O. Das Chloralhydrat, ein neues Hypnoticum und Anaestheticum. 1869;Otto Mullers Verlag, Berlin.
2. Marshal K. E. Jr., Owens A. H. Jr. Bull. Johns Hopkins Hosp. 95:1954;1-18.
3. Maekey F. J., Cooper J. R. J. Pharmacol. Exp. Ther. 135:1962;271-274.
4. Breimer D. D. Clin. Pharmacokin. 2:1977;93-109.
5. Miller R. R., Greenblatt D. I. J. Pharmacol. 19:1979;669-674.
6. Smith M. T. Science. 1985;359.
7. Yung M. W. Audiology. 24:1985;146-148.
8. el-Ad B., Neufeld M. Y., Korczyn A. D. Electroencephalogr. Clin. Neurophysiol. 90:1994;313-315.
9. Lampl Y., Eshel Y., Gilad R., Sarova-Pinchas I. Ann. Emergency Med. 19:1990;674-676.
10. Uden P. C., Miller J. W. J. Amer. Water. Works. Assoc. 75:1983;524-527.
11. Miller J. W., Uden P. C. Environ. Sci. Technol. 17:1983;150-157.
12. EPA, 1982.
13. Sanders V. M., Kauffmann B. M., White K. L. Jr., Douglas K. A., Barnes D. W., Sain L. E., Bradshaw T. J., Bonelleca J. F., Munson A. E. Environ. Health Perspect. 44:1982;137-146.
14. Brunner M., Albertini S., Wurgler F. E. Mutagenesis. 6:1991;65-70.
15. Ogino K., Hobara T., Kobayashi H., Iwamoto S. Bull. Environ. Contam. Toxicol. 44:1990;377-379.
16. Sato A., Nakajima T., Koyama Y. Toxicol. Appl. Pharmacol. 60:1981;8-15.
17. Larson J. L., Bull R. J. J. Toxicol. Environ. Health. 28:1089;395-406.
18. Kawamoto T., Hobara T., Kobayashi H., Iwamoto T., Sakai T., Takano T., Miyazaki Y. Pharmacol. Toxicol. 60:1987;325-329.
19. Abbas R. R., Seckel C. S., Kidney J. K., Fisher J. W. Drug Met. Disp. 24:1996;1340-1346.
20. Robinson B. H. Biochem. Biophys. Acta. 1182:1993;231-244.
21. Curry S. H., Henderson G. N., Lorenz A., Mars D., Stacpoole P. W. Eur. J. Clin. Pharmacol. 40:1991;613-617.
22. Dekant W., Metzler M., Henschler D. Biochem. Pharmacol. 33:1984;2021-2027.
23. Brian B. L., Gracy R. W., Scholes V. E. J. Chromatogr. 66:1972;138-140.
24. Henderson G. N., Darr R. A., Whalen P. O., Curry S. H., Stacpoole P. W. Drug Develop. Ind. Pharm. 20:1994;2425-2437.
25. Curry S. H., Chu P. I., Baumgartner T. G., Stacpoole P. W. Clin. Pharmacol. Ther. 37:1985;89-93.
26. Gorecki D. K. J., Hindmarsh C. A., Hall C. A., Mayers D. J. J. Chromatogr. 528:1990;333-341.
27. Sellers E. M., Lang-Sellers M., Koch-Weser J. J. Clin. Pharmacol. 1978;451-461.
28. Stacpoole P. W. Metabolism. 38:1989;1124-1144.