Preparation and in vitro/in vivo characterisation of a melt pelletised paracetamol/stearic acid sustained release delivery system

Spectroscopy

Volumn 18, Issue 2, 2004, Pages 375-386

  Grassi, Mario ^a   Voinovich, Dario ^a   Grabnar, Iztok ^b   Franceschinis, Erica ^a   Perissutti, Beatrice ^a   Filipovic Grcic, Jelena ^c  

^a UNIVERSITY OF TRIESTE   (Italy)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

^c UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

High shear mixer; In vitro dissolution; In vivo bioavailability studies; Melt pelletisation; Modelling of drug release mechanism; Paracetamol; Sustained release

Indexed keywords

DISSOLUTION; MATHEMATICAL MODELS; MELTING; ORGANIC ACIDS; PELLETIZING; REACTION KINETICS; SCANNING ELECTRON MICROSCOPY; SYNTHESIS (CHEMICAL); X RAY PHOTOELECTRON SPECTROSCOPY;

MELT PELLETIZATION; MELTING BINDERS; STEARIC ACIDS;

DRUG PRODUCTS;

PARACETAMOL; STEARIC ACID;

BIOAVAILABILITY; CONFERENCE PAPER; DIFFUSION; DISSOLUTION; DRUG FORMULATION; MATHEMATICAL MODEL; MELTING POINT; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; SUSTAINED DRUG RELEASE; X RAY PHOTOELECTRON SPECTROSCOPY;

EID: 2442657716     PISSN: 07124813     EISSN: None     Source Type: Journal    
DOI: 10.1155/2004/989502     Document Type: Conference Paper

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