-
1
-
-
0035967245
-
Interactions among drugs for HIV and opportunistic infections
-
Piscitelli SC, Gallicano KD. Interactions among drugs for HIV and opportunistic infections. N Engl J Med. 2001;344:984-996.
-
(2001)
N Engl J Med
, vol.344
, pp. 984-996
-
-
Piscitelli, S.C.1
Gallicano, K.D.2
-
2
-
-
0036114874
-
Therapeutic drug monitoring in HIV infection: Current status and future directions
-
Back D, Gatti G, Fletcher C, et al. Therapeutic drug monitoring in HIV infection: current status and future directions. AIDS. 2002;16(suppl 1):S5-S37.
-
(2002)
AIDS
, vol.16
, Issue.SUPPL. 1
-
-
Back, D.1
Gatti, G.2
Fletcher, C.3
-
3
-
-
0035198762
-
Principles and practice of HIV-protease inhibitor pharmacoenhancement
-
Moyle GJ, Back D. Principles and practice of HIV-protease inhibitor pharmacoenhancement. HIV Med. 2001;2:105-113.
-
(2001)
HIV Med
, vol.2
, pp. 105-113
-
-
Moyle, G.J.1
Back, D.2
-
4
-
-
15144339409
-
The effect of plasma drug concentrations on HIV-1 clearance rate during quadruple drug therapy
-
Hoetelmans RM, Reijers MH, Weverling GJ, et al. The effect of plasma drug concentrations on HIV-1 clearance rate during quadruple drug therapy. AIDS. 1998;12:F111-F115.
-
(1998)
AIDS
, vol.12
-
-
Hoetelmans, R.M.1
Reijers, M.H.2
Weverling, G.J.3
-
5
-
-
0037119026
-
Durability and predictors of success of highly active antiretroviral therapy for ambulatory HIV-infected patients
-
Palella FJ Jr, Chmiel JS, Moorman AC, Holmberg SD. Durability and predictors of success of highly active antiretroviral therapy for ambulatory HIV-infected patients. AIDS. 2002;16:1617-1626.
-
(2002)
AIDS
, vol.16
, pp. 1617-1626
-
-
Palella Jr., F.J.1
Chmiel, J.S.2
Moorman, A.C.3
Holmberg, S.D.4
-
6
-
-
0033371825
-
Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors
-
Profit L, Eagling VA, Back DJ. Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors. AIDS. 1999;13:1623-1627.
-
(1999)
AIDS
, vol.13
, pp. 1623-1627
-
-
Profit, L.1
Eagling, V.A.2
Back, D.J.3
-
7
-
-
0000712439
-
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
-
Cordon-Cardo C, O'Brien JP, Casals D, et al. Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. Proc Natl Acad Sci U S A. 1989;86:695-698.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 695-698
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Casals, D.3
-
8
-
-
0032732512
-
The relationship between ritonavir plasma levels and side-effects: Implications for therapeutic drug monitoring
-
Gatti G, Di Biagio A, Casazza R, et al. The relationship between ritonavir plasma levels and side-effects: implications for therapeutic drug monitoring. AIDS. 1999;13:2083-2089.
-
(1999)
AIDS
, vol.13
, pp. 2083-2089
-
-
Gatti, G.1
Di Biagio, A.2
Casazza, R.3
-
9
-
-
1642315800
-
The metabolic effects of lopinavir/ritonavir in HIV-negative men
-
Lee GA, Seneviratne T, Noor MA, et al. The metabolic effects of lopinavir/ritonavir in HIV-negative men. AIDS. 2004;18:641-649.
-
(2004)
AIDS
, vol.18
, pp. 641-649
-
-
Lee, G.A.1
Seneviratne, T.2
Noor, M.A.3
-
10
-
-
0029025655
-
Recent advances: The cytochrome P450 enzymes
-
Slaughter RL, Edwards DJ. Recent advances: the cytochrome P450 enzymes. Ann Pharmacother. 1995;29:619-624.
-
(1995)
Ann Pharmacother
, vol.29
, pp. 619-624
-
-
Slaughter, R.L.1
Edwards, D.J.2
-
11
-
-
0025269106
-
Recent developments in hepatic drug oxidation. Implications for clinical pharmacokinetics
-
Brosen K. Recent developments in hepatic drug oxidation. Implications for clinical pharmacokinetics. Clin Pharmacokinet. 1990;18:220-239.
-
(1990)
Clin Pharmacokinet
, vol.18
, pp. 220-239
-
-
Brosen, K.1
-
12
-
-
2442649904
-
Optimising TDM in HIV clinical care: A practical guide to performing therapeutic drug monitoring (TDM) for antiretroviral agents
-
April
-
Back D, Blaschke T, Boucher C, et al. Optimising TDM in HIV clinical care: a practical guide to performing therapeutic drug monitoring (TDM) for antiretroviral agents. TDM Guidelines. Version 1.0. April 2003. Available at: http://www.hivpharmacology.com. Accessed April 2, 2004.
-
(2003)
TDM Guidelines. Version 1.0
-
-
Back, D.1
Blaschke, T.2
Boucher, C.3
-
13
-
-
0033010638
-
Comparative in vitro and in vivo inhibition of cytochrome P450 CYP1A2, CYP2D6, and CYP3A by H2-receptor antagonists
-
Martinez C, Albet C, Agundez JA, et al. Comparative in vitro and in vivo inhibition of cytochrome P450 CYP1A2, CYP2D6, and CYP3A by H2-receptor antagonists. Clin Pharmacol Ther. 1999;65:369-376.
-
(1999)
Clin Pharmacol Ther
, vol.65
, pp. 369-376
-
-
Martinez, C.1
Albet, C.2
Agundez, J.A.3
-
14
-
-
12244313733
-
Pharmacokinetics of saquinavir co-administered with cimetidine
-
Boffito M, Carriero P, Trentini L, et al. Pharmacokinetics of saquinavir co-administered with cimetidine. J Antimicrob Chemother. 2002;50:1081-1084.
-
(2002)
J Antimicrob Chemother
, vol.50
, pp. 1081-1084
-
-
Boffito, M.1
Carriero, P.2
Trentini, L.3
-
15
-
-
0033951462
-
Therapeutic drug monitoring of antiretrovirals in human immunodeficiency virus infection
-
Back DJ, Khoo SH, Gibbons SE, et al. Therapeutic drug monitoring of antiretrovirals in human immunodeficiency virus infection. Ther Drug Monit. 2000;22:122-126.
-
(2000)
Ther Drug Monit
, vol.22
, pp. 122-126
-
-
Back, D.J.1
Khoo, S.H.2
Gibbons, S.E.3
-
16
-
-
0020059409
-
Related disposition of ketoconazole, an oral antifungal, in humans
-
Brass C, Galgiani JN, Blaschke TF, et al. Related disposition of ketoconazole, an oral antifungal, in humans. Antimicrob Agents Chemother. 1982;21:151-158.
-
(1982)
Antimicrob Agents Chemother
, vol.21
, pp. 151-158
-
-
Brass, C.1
Galgiani, J.N.2
Blaschke, T.F.3
-
17
-
-
0036135397
-
Interaction of common azole antifungals with P glycoprotein
-
Wang E, Lew K, Casciano CN, et al. Interaction of common azole antifungals with P glycoprotein. Antimicrob Agents Chemother. 2002;46:160-165.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 160-165
-
-
Wang, E.1
Lew, K.2
Casciano, C.N.3
-
19
-
-
0021110870
-
Hepatic reactions during ketoconazole treatment
-
Janssen PA, Symoens JE. Hepatic reactions during ketoconazole treatment. Am J Med. 1983;74(1B):80-85.
-
(1983)
Am J Med
, vol.74
, Issue.1 B
, pp. 80-85
-
-
Janssen, P.A.1
Symoens, J.E.2
-
20
-
-
0001405585
-
Evaluation of the pharmacokinetics of multiple dose ritonavir and ketoconazole in combination
-
Abstract PIII-94
-
Bertz R, Wong C, Carothers L, et al. Evaluation of the pharmacokinetics of multiple dose ritonavir and ketoconazole in combination [abstract]. Clin Pharmacol Ther. 1998;63:228. Abstract PIII-94.
-
(1998)
Clin Pharmacol Ther
, vol.63
, pp. 228
-
-
Bertz, R.1
Wong, C.2
Carothers, L.3
-
21
-
-
2442666217
-
-
Hertfordshire, UK: Roche Registration Limited
-
Fortovase [package insert]. Hertfordshire, UK: Roche Registration Limited; 1999.
-
(1999)
Fortovase [Package Insert]
-
-
-
22
-
-
0035041368
-
The interaction of saquinavir (soft gel capsule) with ketoconazole, erythromycin and rifampicin: Comparison of the effect in healthy volunteers and in HIV-infected patients
-
Grub S, Bryson H, Goggin T, et al. The interaction of saquinavir (soft gel capsule) with ketoconazole, erythromycin and rifampicin: comparison of the effect in healthy volunteers and in HIV-infected patients. Eur J Pharmacol. 2001;57:115-121.
-
(2001)
Eur J Pharmacol
, vol.57
, pp. 115-121
-
-
Grub, S.1
Bryson, H.2
Goggin, T.3
-
23
-
-
2442690060
-
-
Hertfordshire, UK: Roche Registration Limited
-
Invirase [package insert]. Hertfordshire, UK: Roche Registration Limited; 1999.
-
(1999)
Invirase [Package Insert]
-
-
-
24
-
-
0034525426
-
Effect of ketoconazole on ritonavir and saquinavir concentrations in plasma and cerebrospinal fluid from patients infected with human immunodeficiency virus
-
Khaliq Y, Gallicano K, Venance S, et al. Effect of ketoconazole on ritonavir and saquinavir concentrations in plasma and cerebrospinal fluid from patients infected with human immunodeficiency virus. Clin Pharmacol Ther. 2000;68:637-646.
-
(2000)
Clin Pharmacol Ther
, vol.68
, pp. 637-646
-
-
Khaliq, Y.1
Gallicano, K.2
Venance, S.3
-
25
-
-
0033979509
-
Itraconazole as an alternative for ritonavir liquid formulation when combined with saquinavir
-
Koks CH, van Heeswijk RP, Veldkamp AI, et al. Itraconazole as an alternative for ritonavir liquid formulation when combined with saquinavir. AIDS. 2000;14:89-90.
-
(2000)
AIDS
, vol.14
, pp. 89-90
-
-
Koks, C.H.1
Van Heeswijk, R.P.2
Veldkamp, A.I.3
-
26
-
-
0008950421
-
Steady-state pharmacokinetics (PK) of saquinavir (SQV) with and without two doses of itraconazole in HIV-1+ Thai patients: HIV NAT001.2 substudy
-
July 9-14; Durban, South Africa. Abstract WeOrB545
-
Cardiello P, Kroon E, Hoetelmans R, et al. Steady-state pharmacokinetics (PK) of saquinavir (SQV) with and without two doses of itraconazole in HIV-1+ Thai patients: HIV NAT001.2 substudy. Presented at the 13th International AIDS Conference; July 9-14, 2000; Durban, South Africa. Abstract WeOrB545.
-
(2000)
13th International AIDS Conference
-
-
Cardiello, P.1
Kroon, E.2
Hoetelmans, R.3
-
27
-
-
0034747669
-
Inhibition of human cytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors
-
von Moltke LL, Greenblatt DJ, Granda BW, et al. Inhibition of human cytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors. J Clin Pharmacol. 2001;41:85-91.
-
(2001)
J Clin Pharmacol
, vol.41
, pp. 85-91
-
-
Von Moltke, L.L.1
Greenblatt, D.J.2
Granda, B.W.3
-
28
-
-
0032125527
-
Pharmacokinetic drug-drug interaction study of delavirdine and indinavir in healthy volunteers
-
Ferry JJ, Herman BD, Carel BJ, et al. Pharmacokinetic drug-drug interaction study of delavirdine and indinavir in healthy volunteers. J Acquir Immune Defic Syndr Hum Retrovirol. 1998;18:252-259.
-
(1998)
J Acquir Immune Defic Syndr Hum Retrovirol
, vol.18
, pp. 252-259
-
-
Ferry, J.J.1
Herman, B.D.2
Carel, B.J.3
-
29
-
-
0033823238
-
Pharmacokinetic interaction of amprenavir in combination with efavirenz or delavirdine in HIV-infected children
-
Wintergerst U, Erigelhorn C, Kurowski M, et al. Pharmacokinetic interaction of amprenavir in combination with efavirenz or delavirdine in HIV-infected children. AIDS. 2000;14:1866-1868.
-
(2000)
AIDS
, vol.14
, pp. 1866-1868
-
-
Wintergerst, U.1
Erigelhorn, C.2
Kurowski, M.3
-
30
-
-
0037238536
-
Pharmacokinetic interaction between amprenavir and delavirdine after multiple-dose administration in healthy volunteers
-
Justesen US, Klitgaard NA, Brosen K, Pedersen C. Pharmacokinetic interaction between amprenavir and delavirdine after multiple-dose administration in healthy volunteers. Br J Clin Pharmacol. 2003;55:100-106.
-
(2003)
Br J Clin Pharmacol
, vol.55
, pp. 100-106
-
-
Justesen, U.S.1
Klitgaard, N.A.2
Brosen, K.3
Pedersen, C.4
-
31
-
-
0036917788
-
Pharmacokinetic interaction between amprenavir and delavirdine: Evidence of induced clearance by amprenavir
-
Tran JQ, Petersen C, Garrett M, et al. Pharmacokinetic interaction between amprenavir and delavirdine: evidence of induced clearance by amprenavir. Clin Pharmacol Ther. 2002;72:615-626.
-
(2002)
Clin Pharmacol Ther
, vol.72
, pp. 615-626
-
-
Tran, J.Q.1
Petersen, C.2
Garrett, M.3
-
32
-
-
0042778073
-
-
Princeton, NJ: Bristol-Myers Squibb
-
Reyataz [package insert]. Princeton, NJ: Bristol-Myers Squibb; 2003.
-
(2003)
Reyataz [Package Insert]
-
-
-
33
-
-
2442651149
-
Pharmacokinetics (PK) of saquinavir-hard gel capsules (SQV-HGC) when combined with atazanavir (ATV) as once a day combination (1200/400) in highly experienced HIV-positive patients
-
July 13-16; Paris. Poster 847
-
Seminari E, Schira G, Guffanti M, et al. Pharmacokinetics (PK) of saquinavir-hard gel capsules (SQV-HGC) when combined with atazanavir (ATV) as once a day combination (1200/400) in highly experienced HIV-positive patients. Presented at the 2nd International AIDS Society Conference on HIV Pathogenesis and Treatment; July 13-16, 2003; Paris. Poster 847.
-
(2003)
2nd International AIDS Society Conference on HIV Pathogenesis and Treatment
-
-
Seminari, E.1
Schira, G.2
Guffanti, M.3
-
34
-
-
0346154504
-
Efficacy and safety of atazanavir (ATV) with ritonavir (RTV) or saquinavir (SQV) versus lopinavir/ritonavir (LPV/RTV) in combination with tenofovir (TFV) and one NRTI in patients who have experienced virologic failure to multiple HAART regimens: 16-Week results from BMS AI424-045 [abstract]
-
Abstract 118
-
Badaro R, DeJesus E, Lazzarin A, et al. Efficacy and safety of atazanavir (ATV) with ritonavir (RTV) or saquinavir (SQV) versus lopinavir/ritonavir (LPV/RTV) in combination with tenofovir (TFV) and one NRTI in patients who have experienced virologic failure to multiple HAART regimens: 16-week results from BMS AI424-045 [abstract]. Antivir Ther. 2003;8(suppl 1):S212. Abstract 118.
-
(2003)
Antivir Ther
, vol.8
, Issue.SUPPL. 1
-
-
Badaro, R.1
DeJesus, E.2
Lazzarin, A.3
-
35
-
-
0030830568
-
Saquinavir pharmacokinetics alone and in combination with nelfinavir in HIV-infected patients
-
Merry C, Barry MG, Mulcahy F, et al. Saquinavir pharmacokinetics alone and in combination with nelfinavir in HIV-infected patients. AIDS. 1997;11:F117-F120.
-
(1997)
AIDS
, vol.11
-
-
Merry, C.1
Barry, M.G.2
Mulcahy, F.3
-
36
-
-
12944327927
-
The SPICE study: 48-Week activity of combinations of saquinavir soft gelatin and nelfinavir with and without nucleoside analogues. Study of Protease Inhibitor Combinations in Europe
-
Moyle G, Pozniak A, Opravil M, et al. The SPICE study: 48-week activity of combinations of saquinavir soft gelatin and nelfinavir with and without nucleoside analogues. Study of Protease Inhibitor Combinations in Europe. J Acquir Immune Defic Syndr. 2000;23:128-137.
-
(2000)
J Acquir Immune Defic Syndr
, vol.23
, pp. 128-137
-
-
Moyle, G.1
Pozniak, A.2
Opravil, M.3
-
37
-
-
1842450852
-
Sex-based differences in saquinavir pharmacology and virologic response in AIDS Clinical Trials Group study 359
-
Fletcher CV, Jiang H, Brundage RC, et al. Sex-based differences in saquinavir pharmacology and virologic response in AIDS Clinical Trials Group study 359. J Infect Dis. 2004;189:1176-1184.
-
(2004)
J Infect Dis
, vol.189
, pp. 1176-1184
-
-
Fletcher, C.V.1
Jiang, H.2
Brundage, R.C.3
-
38
-
-
0030482468
-
Identification of 6′,7′-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice
-
Edwards DJ, Bellevue FH 3rd, Woster PM. Identification of 6′,7′-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice. Drug Metab Dispos. 1996;24:1287-1290.
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 1287-1290
-
-
Edwards, D.J.1
Bellevue III, F.H.2
Woster, P.M.3
-
39
-
-
0028153858
-
Grapefruit juice and drugs. How significant is the interaction?
-
Bailey DG, Arnold JM, Spence JD. Grapefruit juice and drugs. How significant is the interaction? Clin Pharmacokinet. 1994;26:91-98.
-
(1994)
Clin Pharmacokinet
, vol.26
, pp. 91-98
-
-
Bailey, D.G.1
Arnold, J.M.2
Spence, J.D.3
-
40
-
-
0031908050
-
Grapefruit juice enhances the bioavailability of the HIV protease inhibitor saquinavir in man
-
Kupferschmidt HH, Fattinger KE, Ha HR, et al. Grapefruit juice enhances the bioavailability of the HIV protease inhibitor saquinavir in man. Br J Clin Pharmacol. 1998;45:355-359.
-
(1998)
Br J Clin Pharmacol
, vol.45
, pp. 355-359
-
-
Kupferschmidt, H.H.1
Fattinger, K.E.2
Ha, H.R.3
-
41
-
-
0032865554
-
Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice components
-
Eagling VA, Profit L, Back DJ. Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice components. Br J Clin Pharmacol. 1999;48:543-552.
-
(1999)
Br J Clin Pharmacol
, vol.48
, pp. 543-552
-
-
Eagling, V.A.1
Profit, L.2
Back, D.J.3
-
43
-
-
0031975185
-
Update: Clinically significant cytochrome P-450 drug interaction
-
Michalets EL. Update: clinically significant cytochrome P-450 drug interaction. Pharmacotherapy. 1998;18:84-112.
-
(1998)
Pharmacotherapy
, vol.18
, pp. 84-112
-
-
Michalets, E.L.1
-
44
-
-
0038508970
-
The metabolism of clopidogrel is catalyzed by human cytochrome P450 and is inhibited by atorvastatin
-
Clarke TA, Waskell LA. The metabolism of clopidogrel is catalyzed by human cytochrome P450 and is inhibited by atorvastatin. Drug Metab Dispos. 2003;31:53-59.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 53-59
-
-
Clarke, T.A.1
Waskell, L.A.2
-
45
-
-
0041324754
-
The effects of concurrent atorvastatin therapy on the pharmacokinetics of intravenous midazolam
-
Mc Donnell CG, Harte S, O'Driscoll J, et al. The effects of concurrent atorvastatin therapy on the pharmacokinetics of intravenous midazolam. Anaesthesia. 2003;58:899-904.
-
(2003)
Anaesthesia
, vol.58
, pp. 899-904
-
-
Mc Donnell, C.G.1
Harte, S.2
O'Driscoll, J.3
-
46
-
-
0036291921
-
Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors
-
Williams D, Feely J. Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors. Clin Pharmacokinet. 2002;41:343-370.
-
(2002)
Clin Pharmacokinet
, vol.41
, pp. 343-370
-
-
Williams, D.1
Feely, J.2
-
47
-
-
0025668562
-
Drug interactions with quinolones
-
Janknegt R. Drug interactions with quinolones. J Antimicrob Chemother. 1990;26:7-29.
-
(1990)
J Antimicrob Chemother
, vol.26
, pp. 7-29
-
-
Janknegt, R.1
-
48
-
-
0003896002
-
Midazolam hydroxylation by human liver microsomes in vitro: Inhibition by fluoxetine, norfluoxetine and azole antifungals
-
von Moltke LL, Greenblatt DJ, Schider J, et al. Midazolam hydroxylation by human liver microsomes in vitro: inhibition by fluoxetine, norfluoxetine and azole antifungals. J Clin Pharmacol. 1996;52:231-238.
-
(1996)
J Clin Pharmacol
, vol.52
, pp. 231-238
-
-
Von Moltke, L.L.1
Greenblatt, D.J.2
Schider, J.3
-
49
-
-
0026681168
-
P450 enzymes. Inhibition mechanisms, genetic regulation and effect of liver disease
-
Murray M. P450 enzymes. Inhibition mechanisms, genetic regulation and effect of liver disease. Clin Pharmacokinet. 1992;23:132-146.
-
(1992)
Clin Pharmacokinet
, vol.23
, pp. 132-146
-
-
Murray, M.1
|