Skeletal muscle lipid concentration quantified by magnetic resonance imaging

American Journal of Clinical Nutrition

Volumn 79, Issue 5, 2004, Pages 748-754

  Goodpaster, Bret H ^a   Stenger, V Andrew ^a   Boada, Fernando ^a   McKolanis, Therese ^a   Davis, Denise ^a   Ross, Robert ^b   Kelley, David E ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

Body fat; Magnetic resonance imaging; Obesity; Skeletal muscle; Triacylglycerol

Indexed keywords

LIPID;

ARTICLE; BODY MASS; GASTROCNEMIUS MUSCLE; HUMAN; IMAGING SYSTEM; IN VIVO STUDY; LIPID COMPOSITION; NUCLEAR MAGNETIC RESONANCE IMAGING; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SOLEUS MUSCLE; TIBIALIS ANTERIOR MUSCLE; ADULT; BODY COMPOSITION; CASE CONTROL STUDY; CHEMISTRY; FEMALE; HISTOLOGY; IMAGE QUALITY; MALE; METABOLISM; METHODOLOGY; OBESITY; PHYSIOLOGY;

ADULT; BODY COMPOSITION; BODY MASS INDEX; CASE-CONTROL STUDIES; FEMALE; HUMANS; LIPIDS; MAGNETIC RESONANCE IMAGING; MALE; MUSCLE, SKELETAL; OBESITY; PHANTOMS, IMAGING;

EID: 2442606426     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/79.5.748     Document Type: Article

References (36)

1. Jones DA, Round JM, Edwards RH, Grindwood SR, Tofts PS. Size and composition of the calf and quadriceps muscles in Duchenne muscular dystrophy. A tomographic and histochemical study. J Neurol Sci 1983;60:307-22.
2. Liu M, Chino N, Ishihara T. Muscle damage progression in Duchenne muscular dystrophy evaluated by a new quantitative computed tomography method. Arch Phys Med Rehabil 1993;74:507-14.
3. Ivanyi B, Redekop W, de Jongh R, de Visser M. Computed tomographic study of the skeletal musculature of the lower body in 45 postpolio patients. Muscle Nerve 1998;21:540-2.
4. Nordal HJ, Dietrichson P, Eldevik P, Gronseth K. Fat infiltration, atrophy and hypertrophy of skeletal muscles demonstrated by X-ray computed tomography in neurological patients. Acta Neurol Scand 1988;77:115-22.
5. Sipila S, Suominen H. Effects of strength and endurance training on thigh and leg muscle mass and composition in elderly women. J Appl Physiol 1995;78:334-40.
6. Pan DA, Lillioja S, Kriketos AD, et al. Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes 1997;46:983-8.
7. Shimabukuro M, Koyama K, Chen G, et al. Direct antidiabetic effect of leptin through triglyceride depletion of tissues. Proc Natl Acad Sci U S A 1997;94:4637-41.
8. 13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. Diabetes 1999;48:1600-6.
9. Goodpaster B, Kelley D. Skeletal muscle triglyceride: marker or mediator of obesity-induced insulin resistance in type 2 diabetes mellitus. Curr Diab Rep 2002;2:216-22.
10. Yu C, Chen Y, Cline GW, et al. Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem 2002;277:50230-6.
11. Goodpaster BH, Carlson CL, Visser M, et al. Attenuation of skeletal muscle and strength in the elderly: The Health ABC Study. J Appl Physiol 2001;90:2157-65.
12. 1H-MR-spectroscopy. Magn Reson Med 1997;37:484-93.
13. Szczepaniak LS, Babcock EE, Schick F, et al. Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo. Am J Physiol 1999;276:E977-89.
14. Machannab J, Schick F, Jacob S, Lutz O, Claussen CD. An interleaved sampling strategy for MR spectroscopy in vivo: applications on human calf musculature. Magn Reson Imaging 2000;18:189-97.
15. Jacob S, Machann J, Rett K, et al. Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects. Diabetes 1999;48:1113-9.
16. Petersen KF, Befroy D, Dufour S, et al. Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 2003;300:1140-2.
17. Rico-Sanz J, Hajnal JV, Thomas EL, Mierisova S, Ala-Korpela M, Bell JD. Intracellular and extracellular skeletal muscle triglyceride metabolism during alternating intensity exercise in humans. J Physiol 1998;510:615-22.
18. 1H nuclear magnetic resonance spectroscopy study. J Clin Endocrinol Metab 2000;85:748-54.
19. Schick F, Machman J, Bretchtel K, et al. MRI of muscular fat. Magn Reson Med 2002;47:720 -7.
20. Machann J, Bachmann OP, Brechtel K, et al. Lipid content in the musculature of the lower leg assessed by fat selective MRI: intra- and inter-individual differences and correlation with anthropometric and metabolic data. J Magn Reson Imaging 2003;17:350-7.
21. Goodpaster BH, He J, Watkins S, Kelley DE. Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes. J Clin Endocrinol Metab 2001;86:5755-61.
22. Dixon WT. Simple proton spectroscopic imaging. Radiology 1984;153:189-94.
23. Salustri C, Yang Y, Glover GH. Simple but reliable solutions for spiral MRI gradient design. J Magn Reson 1999;140:347-50.
24. Press W, Teukolsky W, Vetterling W, Flannery B. Numerical recipes in C: the art of scientific computing. Cambridge, United Kingdom: Cambridge University Press, 1992.
25. Gray RE, Tanner CJ, Pories WJ, MacDonald KG, Houmard JA. Effect of weight loss on muscle lipid content in morbidly obese subjects. Am J Physiol 2003;284:E726-32.
26. Greco AV, Mingrone G, Giancaterini A, et al. Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion. Diabetes 2002;51:144-51.
27. Goodpaster BH, Theriault R, Watkins SC, Kelley DE. Intramuscular lipid content is increased in obesity and decreased by weight loss. Metabolism 2000;49:467-72.
28. Romijn JA, Coyle EF, Sidossis LS, et al. Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration. Am J Physiol 1993;265:E380-91.
29. Mitsiopoulos N, Baumgartner RN, Heymsfield SB, Lyons W, Gallagher D, Ross R. Cadaver validation of skeletal muscle measurement by magnetic resonance imaging and computerized tomography. J Appl Physiol 1998;85:115-22.
30. Heymsfield SB, Gallagher D, Visser M, Nuñez C, Wang Z-M. Measurement of skeletal muscle: laboratory and epidemiological methods. J Gerontol 1995;50A:23-9.
31. Ross R, Shaw KD, Rissanen J, Martel Y, de Guise J, Avruch L. Sex differences in lean and adipose tissue distribution by magnetic resonance imaging: anthropometric relationships. Am J Clin Nutr 1994;59:1277-85.
32. Tsubahara A, Chino N, Akaboshi K, Okajima Y, Takahashi H. Age-related changes of water and fat content in muscle estimated by magnetic resonance imaging. Disabil Rehabil 1995;17:298-304.
33. Kent-Braun JA, Ng AV, Young K. Skeletal muscle contractile and non-contractile components in young and older women and men. J Appl Physiol 2000;88:662-8.
34. Askanas V, Engel WK. Distinct subtypes of type I fibers of human skeletal muscle. Neurology 1975;25:879-87.
35. He J, Watkins S, Kelley DE. Skeletal muscle lipid content and oxidative enzyme activity in relation to muscle fiber type in type 2 diabetes and obesity. Diabetes 2001;50:817-23.
36. Lexell J, Downham D, Sjostrom M. Distribution of different fibre types in human skeletal muscles. Fibre type arrangement in m. vastus lateralis from three groups of healthy men between 15 and 83 years. J Neurol Sci 1986;72:211-22.