Intracellular and extracellular skeletal muscle triglyceride metabolism during alternating intensity exercise in humans

Journal of Physiology

Volumn 510, Issue 2, 1998, Pages 615-622

  Rico Sanz, Jesús ^a,d   Hajnal, Joseph V ^a   Thomas, E Louise ^a   Mierisová, Šárka ^b   Ala Korpela, Mika ^c   Bell, Jimmy D ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b SLOVAK UNIVERSITY OF TECHNOLOGY   (Slovakia)

^c WIHURI RESEARCH INSTITUTE   (Finland)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE; CREATINE PHOSPHATE; FATTY ACID; GLUCOSE; GLYCOGEN; TRIACYLGLYCEROL; WATER;

ADULT; ARTICLE; CONTROLLED STUDY; ENERGY METABOLISM; EXERCISE; EXHAUSTION; FEMALE; GASTROCNEMIUS MUSCLE; GLYCOGEN METABOLISM; HEART RATE; HUMAN; HUMAN EXPERIMENT; LOCOMOTION; MALE; MUSCLE CELL; MUSCLE CONTRACTION; MUSCLE FATIGUE; MUSCLE METABOLISM; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SOLEUS MUSCLE; TIBIALIS ANTERIOR MUSCLE; AGED; EXERCISE INTENSITY; HEART RATE VARIABILITY; LIPID METABOLISM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SKELETAL MUSCLE;

ADULT; AGED; EXERCISE; EXTRACELLULAR SPACE; FEMALE; HUMANS; LOCOMOTION; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MUSCLE, SKELETAL; TRIGLYCERIDES;

EID: 0032527974     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1998.615bk.x     Document Type: Article

References (40)

1. BANGSBO, J., JOHANSEN, L., QUISTORFF, B. & SALTIN, B. (1993). NMR and analytic biochemical evaluation of CrP and nucleotides in the human calf during muscle contraction. Journal of Applied Physiology 74, 2034-2039.
2. BERGSTRÖM, J., GUARNIERI, G. & HULTMAN, E. (1971). Carbohydrate metabolism and electrolyte changes in human muscle tissue during heavy work. Journal of Applied Physiology 30, 122-125.
3. 1H-MRS. Magnetic Resonance in Medicine 37, 484-493.
4. BOTTOMLEY, P. A. (1987). Spatial localization in NMR spectroscopy in vivo. Annals of the New York Academy of Sciences 508, 333-348.
5. BOTTOMLEY, P. A., LEE, Y. H. & WEISS, R. G. (1997). Total creatine in muscle: imaging and quantification with proton MR spectroscopy. Radiology 204, 403-410.
6. BRUHN, H., FRAHM, J., GYNGELL, M. L., MERBOLDT, K. D., HÄNICKE, W. & SAUTER, R. (1991). Localized proton NMR spectroscopy using stimulated echoes: applications to human skeletal muscle in vivo. Magnetic Resonance in Medicine 17, 82-94.
7. CARLSON, L. A., EKELUND, L, G. & FRÖBERG, S. O. (1971). Concentration of triglycerides, phospholipids and glycogen in skeletal muscle and of free fatty acids and β-hydroxybutyric acid in blood in man in response to exercise. European Journal of Clinical Investigation 1, 248-254.
8. 2 blockade on exercise endurance and muscle metabolism in humans. Journal of Applied Physiology 66, 548-554.
9. 31P magnetic resonance spectroscopy and biochemical techniques. Experimental Physiology 82, 593-601.
10. DE BEER, R., BACHERT-BAUMANN, P., BOVEE, W. M., CADY, E., CHAMBRON, J., DOMMISSE, R., VAN ECHTELD, C. J., MATHUR-DE VRE, R. & WILLIAMS, S. R. (1995). Quality assessment in in vivo NMR spectroscopy: VI. Multicentre quantification of MRS test signals. Magnetic Resonance Imaging 13, 169-176.
11. EDSTRÖM, L., HULTMAN, E., SAHLIN, K. & SJÖHOLM, H. (1982). The contents of high-energy phosphates in different fibre types in skeletal muscles from rat, guinea-pig and man. Journal of Physiology 332, 47-58.
12. ESSEN, B., HAGENFELDT, L. & KAIJSER, L. (1977). Utilization of blood-borne and intramuscular substrates during continuous and intermittent exercise in man. Journal of Physiology 265, 489-506.
13. ESSEN, B., JANSSON, E., HENRIKSSON, J., TAYLOR, A. & SALTIN, B. (1975). Metabolic characteristics of fibre types in human skeletal muscle. Acta Physiologica Scandinavica 95, 153-165.
14. GADIAN, D. G. (1995). NMR and its Applications to Living Systems. Oxford Science Publications, Oxford University Press, Oxford.
15. GOLLNICK, P. D., PIEHL, K. & SALTIN, B. (1974). Selective glycogen depletion pattern in human muscle fibres after exercise of varying intensity and at varying pedalling rates. Journal of Physiology 241, 45-57.
16. HULTMAN, E. (1967). Studies on muscle metabolism of glycogen and active phosphate in man with special reference to exercise and diet. Scandinavian Journal of Clinical Laboratory and Investigation 19, suppl. 94.
17. HURLEY, J. F., NEMETH, P. M., MARTIN, W. H. III, HAGBERG, J. M., DALSKY, G. P. & HOLLOSZY, J. O, (1986). Muscle triglyceride utilization during exercise: effect of training. Journal of Applied Physiology 60, 562-567.
18. JANSSON, E. & KAIJSER, L. (1982). Effect of diet on the utilization of blood-borne and intramuscular substrates during exercise in man. Acta Physiologica Scandinavica 115, 19-30.
19. JANSSON, E. & KAIJSER, L. (1987). Substrate utilization and enzymes in skeletal muscle of extremely endurance-trained men. Journal of Applied Physiology 62, 999-1005.
20. KIENS, B., ESSEN-GUSTAVSON, B., CHRISTENSEN, N. J. & SALTIN, B. (1993). Skeletal muscle substrate utilization during submaximal exercise in man: effect of endurance training. Journal of Physiology 469, 459-478.
21. KIENS, B., KRISTIANSEN, S., JENSEN, P., RICHTER, E. A. & TURCOTTE, L. P. (1997). Membrane associated fatty acid binding protein (FBAPpm) in human skeletal muscle is increased by endurance training. Biochemical and Biophysical Research Communications 231, 463-465,
22. KIENS, B. & LITHELL, H. (1989). Lipoprotein metabolism influenced by training-induced changes in human skeletal muscle. Journal of Clinical Investigation 83, 558-564.
23. MARTIN, W. H. III, DALSKY, G. P., HURLEY, B. F., MATTHEWS, D. E., BIER, D. M., HAGBERG, J. M., ROGERS, M. A., KING, D. S. & HOLLOSZY, J. O. (1993). Effect of endurance training on plasma free fatty acid turnover and oxidation during exercise. American Journal of Physiology 265, E708-714.
24. MASORO, E. J., ROWELL, L. B., McDONALD, R. M. & STEITERT, B. (1966). Non-utilization of intracellular lipid esters as an energy source for contractile activity. Journal of Biological Chemistry 241, 2626-2634.
25. MENDEZ, J. & KEYS, A. (1960). Density and composition of mamalian muscle. Metabolism 9, 184-188.
26. NORDHEIM, K. & VØLLESTAD, N. K. (1990). Glycogen and lactate metabolism during low-intensity exercise in man. Acta Physiologica Scandinavica 139, 475-484.
27. PHILLIPS, S. M., GREEN, H. J., TARNOPOLSKY, M. A., HEIGENHAUSER, G. J. F., HILL, R. E. & GRANT, S. M. (1996). Effects of training duration on substrate turnover and oxidation during exercise. Journal of Applied Physiology 81, 2182-2191.
28. 13C-NMR measurements of muscle glycogen during low intensity exercise. Journal of Applied Physiology 70, 1836-1844.
29. RICHTER, E. A., KIENS, B. & TURCOTTE, L. (1996). Transport and metabolism of FFA in muscle. Biochemistry of Exercise IX, 97-104.
30. ROMIJN, J. A., COYLE, E. F., SIDOSSIS, L. S., GASTATDELLI, A., HOROWITZ, J. F., ENDERT, E. & WOLFE, R. R. (1993). Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration. American Journal of Physiology 265, E380-391.
31. 31P nuclear magnetic resonance. New England Journal of Medicine 304, 1338-1342.
32. SALTIN, B., HENRIKSSON, J., NYGAARD, E., ANDERSEN, P. & JANSSON, E. (1977). Fibre types and metabolic potentials of skeletal muscles in sedentary man and endurance runners. Annals of the. New York Academy of Sciences 20, 3-29.
33. SCHICK, F., EISMANN, B., JUNG, W. I., BONGERS, H., BUNSE, M. & LUTZ, O. (1993). Comparison of localized proton NMR signals of skeletal muscle and fat tissue in vivo: two lipid compartments in muscle tissue. Magnetic Resonance in Medicine 29, 158-167.
34. SIDOSSIS, L. S., COGGAN, A. R., GASTALDELLI, A. & WOLFE, R. R. (1995). A new correction factor for use in tracer estimations of plasma fatty acid oxidation. American Journal of Physiology 269, E649-656.
35. STANDL, E., LOTZ, N., DEXEL, TH., JANKA, H. U. & KOLB, H. J. (1980). Muscle triglycerides in diabetic subjects. Diabetologia 18, 463-469.
36. STARLING, R. D., TRAPPE, T. A., PARCELL, A. C., KERR, C. G., FINK, W. J. & COSTILL, D. L. (1997). Effects of diet on muscle triglyceride and endurance performance. Journal of Applied Physiology 82, 1185-1189.
37. TURCOTTE, L. P., RICHTER, E. A. & KIENS, B. (1992). Increased plasma FFA uptake and oxidation during prolonged exercise in trained vs.untrained humans. American Journal of Physiology 262, E791-799.
38. VAN DEN BOOGAART, A., VAN ORMONDT, D., PIJNAPPEL, W. W. F., DE BEER, R. & ALA-KORPELA, M. (1994). In Mathematics in Signal Processing III, ed. McWHIRTER, J. G., pp. 175-195. Clarendon Press, Oxford.
39. 31P-NMR signals using the variable projection methods and prior knowledge. Magnetic Resonance in Medicine 6, 92-98.
40. WENDLING, P. S., PETERS, S. J., HEIGENHAUSER, G. J. F. & SPRIET, L. (1996). Variability of triacylglycerol content in human skeletal muscle biopsy samples. Journal of Applied Physiology 81, 1150-1155.