The Tumoricidal Activity of Memory CD8+ T Cells Is Hampered by Persistent Systemic Antigen, but Full Functional Capacity Is Regained in an Antigen-Free Environment

Journal of Immunology

Volumn 172, Issue 10, 2004, Pages 6074-6079

  Den Boer, Annemieke Th ^a   Van Mierlo, Geertje J D ^a   Fransen, Marieke F ^a   Melief, Cornelis J M ^a   Offringa, Rienk ^a   Toes, René E M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; E1A PROTEIN; SYSTEMIC ANTIGEN; UNCLASSIFIED DRUG;

ADENOVIRUS 5; ADENOVIRUS 5 E1A; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; EPITOPE MAPPING; EX VIVO STUDY; GENE DELETION; IMMUNOLOGICAL TOLERANCE; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYSTEMIC CIRCULATION; T LYMPHOCYTE ACTIVATION; TUMOR GROWTH; VACCINATION;

EID: 2442465802     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.10.6074     Document Type: Article

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