Linkage exclusion analysis of two important chromosomal regions for height

Biochemical and Biophysical Research Communications

Volumn 335, Issue 4, 2005, Pages 1287-1292

  Yang, Yan Jun ^b,c   Liu, Yao Zhong ^a   Li, Miao Xin ^b   Lei, Shu Feng ^b   Chen, Xiang Ding ^b   Sun, Xiao ^b   Deng, Hong Wen ^a,c,d  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HUNAN NORMAL UNIVERSITY   (China)

^c Jingzhong University ^*  (China)

^d XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

ER ; Height; Linkage exclusion analysis; Stature

Indexed keywords

ADULT; AGED; ARTICLE; CAUCASIAN; CHROMOSOME; CHROMOSOME 6Q; FEMALE; GENETIC LINKAGE; GENOME; HUMAN; LINKAGE ANALYSIS; MALE; PEDIGREE; PHYSICAL DEVELOPMENT; PRIORITY JOURNAL; SAMPLE;

ADULT; AGED; BODY HEIGHT; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN; FEMALE; GENOTYPE; HUMANS; LINKAGE (GENETICS); MALE; MIDDLE AGED; QUANTITATIVE TRAIT LOCI; UNITED STATES;

EID: 24044529176     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.08.027     Document Type: Article

References (41)

1. J.N. Hirschhorn, C.M. Lindgren, M.J. Daly, A. Kirby, S.F. Schaffner, N.P. Burtt, D. Altshuler, A. Parker, J.D. Rioux, J. Platko, D. Gaudet, T.J. Hudson, L.C. Groop, and E.S. Lander Genomewide linkage analysis of stature in multiple populations reveals several regions with evidence of linkage to adult height Am. J. Hum. Genet. 69 2001 106 116
2. E. Ginsburg, G. Livshits, K. Yakovenko, and E. Kobyliansky Major gene control of human body height, weight and BMI in five ethnically different populations Ann. Hum. Genet. 62 1998 307 322
3. J.F. Xu, E.R. Bleecker, H. Jongepier, T.D. Howard, G.H. Koppelman, D.S. Postma, and D.A. Meyers Major recessive gene(s) with considerable residual polygenic effect regulating adult height: confirmation of genomewide scan results for chromosomes 6, 9, and 12 Am. J. Hum. Genet. 71 2002 646 650
4. T. Arinami, Y. Iijima, K. Yamakawa-Kobayashi, H. Ishiguro, T. Ohtsuki, H. Yanagi, Y. Shimakura, H. Ishikawa, and H. Hamaguchi Supportive evidence for contribution of the dopamine D2 receptor gene to heritability of stature: linkage and association studies Ann. Hum. Genet. 63 1999 147 151
5. J.A. Ellis, M. Stebbing, and S.B. Harrap Significant population variation in adult male height associated with the Y chromosome and the aromatase gene J. Clin. Endocrinol. Metab. 86 2001 4147 4150
6. P. Garnero, O. Bore, S.F.A. Grant, S.H. Ralston, and P.D. Delmas Collagen Ia1 Sp1 polymorphism, bone mass, and bone turnover in healthy French premenopausal women: the OFELY study J. Bone Miner. Res. 13 5 1998 813 817
7. Y. Hasegawa, K. Fujii, M. Yamada, Y. Igarashi, K. Tachibana, T. Tanaka, K. Onigata, Y. Nishi, S. Kato, and T. Hasegawa Identification of novel human GH-1 gene polymorphisms that are associated with growth hormone secretion and height J. Clin. Endocrinol. Metab. 85 2000 1290 1295
8. M. Lorentzon, R. Lorentzon, and P. Nordstrom Vitamin D receptor gene polymorphism is related to bone density, circulating osteocalcin, and parathyroid hormone in healthy adolescent girls J. Bone Miner. Metab. 19 2001 302 307
9. A. Meirhaeghe, L. Fajas, F. Gouilleux, D. Cottel, N. Helbecque, J. Auwerx, and P. Amouyel A functional polymorphism in a STAT5B site of the human PPAR gamma 3 gene promoter affects height and lipid metabolism in a French population Arterioscler. Thromb. Vasc. Biol. 23 2003 289 294
10. M. Minagawa, T. Yasuda, T. Watanabe, K. Minamitani, Y. Takahashi, D. Goltzman, J.H. White, G.N. Hendy, and Y. Kohno Association between AAAG repeat polymorphism in the P3 promoter of the human parathyroid hormone (PTH)/PTH-related peptide receptor gene and adult height, urinary pyridinoline excretion, and promoter activity J. Clin. Endocrinol. Metab. 87 2002 1791 1796
11. J.M. Zmuda, J.A. Cauley, L.H. Kuller, and R.E. Ferrell A common promotor variant in the cytochrome P450c17alpha (CYP17) gene is associated with bioavailability testosterone levels and bone size in men J. Bone Miner. Res. 16 2001 911 917
12. D.A. Cabezas, R. Slaugh, F. Abidi, J.F. Arena, R.E. Stevenson, C.E. Schwartz, and H.A. Lubs A new X linked mental retardation (XLMR) syndrome with short stature, small testes, muscle wasting, and tremor localises to Xq24-q25 J. Med. Genet. 37 2000 658 662
13. B.D. Gelb, G.P. Shi, H.A. Chapman, and R.J. Desnick Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency Science 273 1996 1236 1238
14. B.C. Hamel, A.P. Smits, B.J. Otten, H.B. van-den, H.H. Ropers, and E.C. Mariman Familial X-linked mental retardation and isolated growth hormone deficiency: clinical and molecular findings Am. J. Med. Genet. 64 1996 35 41
15. H.G. Maheshwari, B.L. Silverman, J. Dupuis, and G. Baumann Phenotype and genetic analysis of a syndrome caused by an inactivating mutation in the growth hormone-releasing hormone receptor: dwarfism of Sindh J. Clin. Endocrinol. Metab. 83 1998 4065 4074
16. R.S. Ramesar, J. Greenberg, R. Martin, R. Goliath, S. Bardien, S. Mundlos, and P. Beighton Mapping of the gene for cleidocranial dysplasia in the historical Cape Town (Arnold) kindred and evidence for locus homogeneity J. Med. Genet. 33 1996 511 514
17. M. Raynaud, N. Ronce, A.D. Ayrault, C. Francannet, G. Malpuech, and C. Moraine X linked mental retardation with isolated growth hormone deficiency is mapped to Xq22-Xq27.2 in one family Am. J. Med. Genet. 76 1998 255 261
18. R. Shiang, L.M. Thompson, Y.Z. Zhu, D.M. Church, T.J. Fielder, M. Bocian, S.T. Winokur, and J.J. Wasmuth Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia Cell 78 1994 335 342
19. E. Vitale, C. Specchia, M. Devoto, A. Angius, S. Rong, M. Rocchi, M. Schwalb, L. Demelas, D. Paglietti, S. Manca, C. Mastropaolo, and G. Serra Novel X-linked mental retardation syndrome with short stature maps to Xq24 Am. J. Med. Genet. 103 2001 1 8
20. H.W. Deng, F.H. Xu, Y.Z. Liu, H. Shen, H.Y. Deng, Q.Y. Huang, Y.J. Liu, T. Conway, J.L. Li, K.M. Davies, and R.R. Robert A whole-genome linkage scan suggests several genomic regions potentially containing QTLs underlying the variation of stature Am. J. Med. Genet. 113 2002 29 39
21. F. Geller, A. Dempfle, and T. Gong Genome scan for body mass index and height in the Feamingham. BMC Genetics 4 2003 591 596
22. N. Mukhopadhyay, D.N. Finegold, M.G. Larson, L.A. Cupples, R.H. Myers, and D.E. Weeks A genome-wide scan for loci affecting normal adult height in the framingham heart study Hum. Hered. 55 2003 191 201
23. M. Perola, M. Ohman, T. Hiekkalinna, J. Leppaivuori, P. Pajukanta, M. Wessman, M. Koskenvuo, A. Palotie, K. Lange, J. Kaprio, and L. Peltonen Quantitative-trait-locus analysis of body-mass index and of stature, by combined analysis of genome scans of five Finnish study groups Am. J. Hum. Genet. 69 2001 117 123
24. D.B. Thompson, V. Ossowski, R.C. Janssen, W.C. Knowler, and C. Bogardus Linkage between stature and a region on chromosome 20 and analysis of a candidate gene, bone morphogenetic protein 2 Am. J. Med. Genet. 59 1995 495 500
25. G. Willemsen, D.I. Boomsama, A.L. Beem, J.M. Vink, P.E. Slagboom, and D. Posthuma QTLS for height: results of a full genome scan in Dutch sibling pairs Eur. J. Hum. Genet. 2004 1 9
26. S. Wiltshire, T.M. Frayling, A.T. Hattersley, G.A. Hitman, M. Walker, J.C. Levy, S.O. Rahilly, C.J. Groves, S. Menzel, L.R. Cardon, and M.I. Maccrthy Evidence for linkage of stature to chromosome 3p26 in large UK family data set ascertained for type 2 diabetes Am. J. Hum. Genet. 70 2002 543 546
27. X. Wu, R.S. Cooper, and E. Boerwinkle Combined analysis of genomewide scans for adult height: results from the NHLBI Family Blood Pressure Program Eur. J. Hum. Genet. 11 2003 271 274
28. A.G. Commuzzie, L. Almasy, S.A. Cole, O. Boss, J.P. Giacobino, P. Muzzin, M.P. Stern, J.W. MacCluer, J. Blangero, and J.E. Hixson Linkage exclusion analysis of the chromosome 11 region containing UCP2 and UCP3 with obesity-related phenotypes in Mexican Americans Int. J. Obesity 24 2000 1065 1068
29. H.W. Deng, J. Li, and R.R. Recker LOD score exclusion analyses of candidate genes with random population samples Ann. Hum. Genet. 65 2001 313 329
30. H.W. Deng LOD score exclusion analysis for candidate QTLs using random population samples Genetica 119 2003 303 315
31. V. Kusec, A.S. Virdi, R. Prince, and J.T. Triffit Localization of estrogen receptor-in human and rabbit skeletal tissues J. Clin. Endocrinol. Metab. 83 1998 2421 2428
32. H.W. Deng, and J. Li The effects of selected sampling on the transmission disequilibrium test of a quantitative trait locus Genet Res. 79 2002 161 174
33. N. Risch, and H. Zhang Extreme discordant sib pairs for mapping quantitative trait loci in humans Science 268 1995 1584 1589
34. H.W. Deng, Y. Zhou, R.R. Recker, M.L. Johnson, and J. Li Fragment size difference between multiplex and singleplex PCR products and their practical implications Biotechniques 29 2000 298
35. J.L. Li, H.Y. Deng, D.B. Lai, R.R. Recke, and H.W. Deng Towards high-throughput genotyping: a dynamic and automatic software for manipulating large-scale genotype data using fluorescently labeled dinucleotide markers Genome Res. 11 2001 1304 1314
36. J.R. O'Connell, and D.E. Weeks PedCheck: a program for identification of genotype incompatibilities in linkage analysis Am. J. Hum. Genet. 63 1998 259 266
37. L. Almasy, and J. Blangero Multipoint quantitative-trait linkage analysis in general pedigrees Am. J. Hum. Genet. 62 1998 1198 1211
38. H.W. Deng, J. Li, J.L. Li, R. Dowd, K.M. Davies, M. Johnson, G. Gong, H. Deng, and R.R. Recker Association of estrogen receptor-alpha genotypes with body mass index in normal healthy postmenopausal Caucasian women J. Clin. Endocrinol. Metab. 85 2000 2748 2751
39. H.W. Deng, J. Li, J.L. Li, M. Johnson, G. Gong, and R.R. Recker Association of VDR and estrogen receptor genotypes with bone mass in postmenopausal Caucasian women: different conclusions with different analyses and the implications Osteoporosis Int. 9 1999 499 507
40. E. Lander, and L. Kruglyak Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results Nat. Genet. 11 1995 241 247
41. M. Lorentzon, R. Lorentzon, T. Backstrom, and P. Nordstrom Estrogen receptor gene polymorphism, but not estradiol levels, is related to bone density in healthy adolescent boys: a cross-sectional and longitudinal study J. Clin. Endocrinol. Metab. 84 1999 4597 4601