Supportive evidence for contribution of the dopamine D2 receptor gene to heritability of stature: Linkage and association studies

Annals of Human Genetics

Volumn 63, Issue 2, 1999, Pages 147-151

  Arinami, T ^a   Iijima, Y ^a   Yamakawa Kobayashi, K ^a   Ishiguro, H ^a   Ohtsuki, T ^a   Yanagi, H ^a   Shimakura, Y ^a   Ishikawa, H ^a   Hamaguchi, H ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR BLOCKING AGENT;

ADOLESCENT; ADULT; ARTICLE; BODY HEIGHT; DEVELOPMENTAL GENETICS; DINUCLEOTIDE REPEAT; FEMALE; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENOTYPE; HERITABILITY; HUMAN; JAPAN; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROMOTER REGION; SCHOOL CHILD;

ADOLESCENT; ADULT; BODY HEIGHT; BODY MASS INDEX; CHILD; CHOLESTEROL; DINUCLEOTIDE REPEATS; DNA; FEMALE; GENOTYPE; HUMANS; LINKAGE (GENETICS); MALE; MIDDLE AGED; NUCLEAR FAMILY; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RECEPTORS, DOPAMINE D2; STATISTICS;

EID: 0032778257     PISSN: 00034800     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1469-1809.1999.6320147.x     Document Type: Article

References (23)

1. ARINAMI, T., GAO, M., HAMAGUCHI, H. & TORU, M. (1997). A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia. Hum. Mol. Genet. 6, 577-582.
2. 2 receptor (DRD2) as a major gene in obesity and height. Biochem. Med. Metab. Biol. 50, 176-185.
3. CRAVCHIK, A., SIBLEY, D. R. & GEJMAN, P. V. (1996). Functional analysis of the human D2 dopamine receptor missense variants. Journal of Biological Chemistry 271, 26013-26017.
4. DAVENPORT, C. B. (1917). Inheritance of stature. Genetics 2, 313-389.
5. ELSTON, R. C., GEORGE, V. T. & SORANT, A. J. M. (1994). S.A.G.E. Users Guide, Release 2.2. Department of Biometry and Genetics, LSM Medical Center, New Orleans.
6. ENGELHARDT, D. M., POLIZOS, P., WAIZER, J. & HOFFMAN, S. P. (1973). A double-blind comparison of fluphenazine and haloperidol in outpatient schizophrenic children. J. Autism Child Schizophr. 2, 128-137.
7. GEJMAN, P. V., RAM, A., GELERNTER, J., FRIEDMAN, E., CAO, Q., PICKAR, D., BLUM, K., NOBLE, E. P., KRANZLER, H. R., O'MALLEY, S., HAMER, D. H., WHITSITT, F., RAO, P., DELISI, L. E., VIRKKUNEN, M., LINNOILA, M., GOLDMAN, D. & GERSHON, E. S. (1994). No structural mutation in the dopamine D2 receptor gene in alcoholism or schizophrenia. Analysis using denaturing gradient gel electrophoresis. JAMA 271, 204-208.
8. GREELEY, G. H. J., LIPTON, M. A. & KIZER, J. S. (1982). Effects of chronic perphenazine treatment on growth and endocrine function in developing rats. J Pharmacol. Exp. Ther. 220, 133-138.
9. GREENHILL, L., PUIG-ANTICH, J., CHAMBERS, W., RUBENSTEIN, B., HALPERN, B. & SACHER, E. J. (1981). Growth hormone, prolactin and growth responses in hyperkinetic boys treated with D-amphetamine. Am. Acad. Child Psychiatry 20, 84-103.
10. HAUGE, X. Y., GRANDY, D. K., EUBANKS, J. H., EVANS, G. A., CIVELLI, O. & LITT, M. (1991). Detection and characterization of additional DNA polymorphisms in the dopamine D2 receptor gene. Genomics 10, 527-30.
11. INIGUEZ, C., TAMAYO, P., GOMEZ, A., & GAYOSO, M. J. (1995). Effects of perinatal administration of haloperidol on GH pituitary contents and serum levels during the first postnatal month. Neuroendocrinology 62, 308-312.
12. ITOKAWA, M., ARINAMI, T., FUTAMURA, N., HAMAGUCHI, H., & TORU, M. (1993). A structural polymorphism of human dopamine D2 receptor D2(Ser311 → Cys). Biochem Biophys Res Commun 196, 1369-1375.
13. JABER, M., TISON, F., FOURNIER, M. C., & BLOCH, B. (1994). Differential influence of haloperidol and sulpiride on dopamine receptors and peptide mRNA levels in the rat striatum and pituitary. Brain Res Mol Brain Res 23, 14-20.
14. JÖNSSON, E. G., NÖTHEN, M. M., NEIDT, H., FARDE, L., PROPPING, P. & SEDVALL, G. C. (1998). Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density in vivo of healthy volunteers. Am. J. Med. Genet. 81, 497.
15. KRUGLYAK, L. & LANDER, E. S. (1995). Complete multipoint sib-pair analysis of qualitative and quantitative traits [see comments]. Am. J. Hum. Genet. 57, 439-454.
16. MCANDREWS, J. B., CASE, Q. & TREFFERT, D. A. (1972). Effects of prolonged phenothiazine intake on psychotic and other hospitalized children. J. Autism Child Schizophr. 2, 75-91.
17. MÜLLER, E. E. (1987). Neural control of somatotrophic function. Physiological Reviews 67, 962-1053.
18. PEARSON, K., & LEE, A. (1903). Inheritance of physical characters. Biometrika 2, 357-462.
19. PHILLIPS, K., & MATHENY, A. P. J. (1990). Quantitative genetic analysis of longitudinal trends in height: preliminary results from the Louisville Twin Study. Acta Genet. Med. Gemellol. 39, 143-163
20. PLATT, J. E., FRIEDHOFF, A. J., BROMAN, S. H., BOND, R. N., LASKA, E. & LIN, S. P. (1988). Effects of prenatal exposure to neuroleptic drugs on children's growth. Neuropsychopharmacology 1, 205-212.
21. PUIG-ANTICH, J., GREENHILL, L. L., SASSINI, J. & SACHAR, E. J. (1978). Growth hormone, prolactin and cortisol response and growth patterns in hyperkinetic children treated with dextroamphetamine: Preliminary reports. J. Am. Acad. Child Psychiatry 17, 457-475.
22. SIMEON, J., GROSS, M. & MUELLER, J. (1977). Neuroleptic drug effect on children's body weight and height. Psychopharm Bull. 13, 50-53.
23. THOMPSON, E. B., OSSOWSKI, V., JANSSEN, R. C., KNOWLER, W. C. & BOGARDUS, C. (1995). Linkage between stature and a region on chromosome 20 and analysis of a cnadidate gene, bone morphogenetic protein 2. Am. J. Med. Genet. 59, 495-500.