Major recessive gene(s) with considerable residual polygenic effect regulating adult height: Confirmation of genomewide scan results for chromosomes 6, 9, and 12

American Journal of Human Genetics

Volumn 71, Issue 3, 2002, Pages 646-650

  Xu, Jianfeng ^a   Bleecker, Eugene R ^a   Jongepier, Hajo ^b   Howard, Timothy D ^a   Koppelman, Gerard H ^b   Postma, Dirkje S ^b   Meyers, Deborah A ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; ASTHMA; BODY HEIGHT; CHROMOSOME 12; CHROMOSOME 6Q; CHROMOSOME 9; FAMILY STUDY; FEMALE; GENE SEGREGATION; GENETIC TRAIT; HUMAN; LINKAGE ANALYSIS; MALE; MOLECULAR MODEL; MULTIFACTORIAL INHERITANCE; NORMAL HUMAN; PRIORITY JOURNAL; RECESSIVE GENE;

EID: 0036724841     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/342216     Document Type: Article

References (17)

1. A new look at the statistical model identification
2. Multipoint quantitative-trait linkage analysis in general pedigrees
3. Genomewide scans of complex human diseases: True linkage is hard to find
4. Regressive logistic models for familial disease and other binary traits
5. A cross-sectional examination of height, weight, and body mass index in adult twins
6. Estimation of genetic model parameters: Variables correlated with a quantitative phenotype exhibiting major locus inheritance
7. Genomewide linkage analysis of stature in multiple populations reveals several regions with evidence of linkage to adult height
8. On the laws of inheritance in man. I. Inheritance of physical characters
9. Quantitative-trait-locus analysis of body-mass index and of stature, by combined analysis of genome scans of five Finnish study groups
10. Quantitative genetic analysis of longitudinal trends in height: Preliminary results from the Louisville Twin Study
11. Genetic susceptibility to asthma: Bronchial hyperresponsiveness coinherited with a major gene for atopy
12. The genetic contribution to stature
13. Path analysis of family resemblance with temporal trends: Applications to height, weight, and Quetelet index in northeastern Brazil
14. Relative effect of genetic and environmental factors on body height: Differences across birth cohorts among Finnish men and women
15. Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis
16. Evidence for linkage of stature to chromosome 3p26 in a large UK family data set ascertained for type 2 diabetes
17. Major genes regulating total serum immunoglobulin E levels in families with asthma