메뉴 건너뛰기




Volumn 127, Issue 3-4, 2005, Pages 89-93

New insights on genetics of malignant melanoma;Najnovije spoznaje o genskoj osnovi melanoma

Author keywords

Melanoma genetics; Skin neoplasms genetics

Indexed keywords

B RAF KINASE; CYCLIN DEPENDENT KINASE 4; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

EID: 24044490617     PISSN: 00243477     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (2)

References (74)
  • 2
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996;87:159-70.
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 3
    • 0033121055 scopus 로고    scopus 로고
    • E-cadherin downregulation in cancer: Fuel on the fire?
    • Guilford P. E-cadherin downregulation in cancer: fuel on the fire? Mol Med Today 1999;5:172-7.
    • (1999) Mol Med Today , vol.5 , pp. 172-177
    • Guilford, P.1
  • 4
    • 1842858963 scopus 로고    scopus 로고
    • Cellular adhesion pathways and metastatic potential of human melanoma
    • McGary EC, Lev DC, Bar-Eli M. Cellular adhesion pathways and metastatic potential of human melanoma. Cancer Biol Ther 2002;1:459-65.
    • (2002) Cancer Biol Ther , vol.1 , pp. 459-465
    • McGary, E.C.1    Lev, D.C.2    Bar-Eli, M.3
  • 5
    • 2942548177 scopus 로고    scopus 로고
    • E-cadherin role in normal and malignanat cells
    • Pećina-Šlaus N. E-cadherin role in normal and malignanat cells. Cancer Cell International 2003;3:17. [http://www.cancerci.com/content/3/ 1/17)].
    • (2003) Cancer Cell International , vol.3 , pp. 17
    • Pećina-Šlaus, N.1
  • 6
    • 0038795112 scopus 로고    scopus 로고
    • Oncogenes in melanoma
    • Polsky D, Cordon-Cardo C. Oncogenes in melanoma. Oncogene 2003;22: 3087-91.
    • (2003) Oncogene , vol.22 , pp. 3087-3091
    • Polsky, D.1    Cordon-Cardo, C.2
  • 8
    • 33645482827 scopus 로고    scopus 로고
    • Genetic and molecular pathology of melanoma
    • Barnhill RL, Piepkorn M, Busam KJ, ur. New York: Springer; str. 20-36
    • Piepkorn M. Genetic and molecular pathology of melanoma. U: Barnhill RL, Piepkorn M, Busam KJ, ur. Pathology of melanocytic nevi and malignant melanoma. New York: Springer; 2004, str. 20-36.
    • (2004) Pathology of Melanocytic Nevi and Malignant Melanoma
    • Piepkorn, M.1
  • 9
    • 0014658112 scopus 로고
    • Elektronska mikroskopska istraživanja melanotičnog i amelanotičnog melanoma hrčka
    • Oberman B, Ljubešić N. Elektronska mikroskopska istraživanja melanotičnog i amelanotičnog melanoma hrčka. Liječ Vjesn 1969;91:947-53.
    • (1969) Liječ Vjesn , vol.91 , pp. 947-953
    • Oberman, B.1    Ljubešić, N.2
  • 11
  • 12
    • 0042887050 scopus 로고    scopus 로고
    • The genetics of malignant melanoma: Lessons from mouse and man
    • Chin L. The genetics of malignant melanoma: lessons from mouse and man. Nature Rev 2003;3:559-70.
    • (2003) Nature Rev , vol.3 , pp. 559-570
    • Chin, L.1
  • 17
    • 0028085975 scopus 로고
    • Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus
    • Kamb A, Shattuck-Eidens D, Eeles R i sur. Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus. Nature Genet 1994;8:23-6.
    • (1994) Nature Genet , vol.8 , pp. 23-26
    • Kamb, A.1    Shattuck-Eidens, D.2    Eeles, R.3
  • 18
    • 0029664339 scopus 로고    scopus 로고
    • Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
    • Zuo L, Weger J, Yang Q i sur. Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma. Nature Genet 1996;12:97-9.
    • (1996) Nature Genet , vol.12 , pp. 97-99
    • Zuo, L.1    Weger, J.2    Yang, Q.3
  • 19
    • 0032169516 scopus 로고    scopus 로고
    • The alternative product from the human CDKN2A locus, p 14(ARF), participates in a regulatory loop with p53 and MDM2
    • Stott FJ, Bates S, James MC, McConnell BB. The alternative product from the human CDKN2A locus, p 14(ARF), participates in a regulatory loop with p53 and MDM2. EMBO J 1998;17:5001-14.
    • (1998) EMBO J , vol.17 , pp. 5001-5014
    • Stott, F.J.1    Bates, S.2    James, M.C.3    McConnell, B.B.4
  • 20
    • 0036753176 scopus 로고    scopus 로고
    • Skin colour and skin cancer: MC1R, the genetic link
    • Sturm RA. Skin colour and skin cancer: MC1R, the genetic link. Melanoma Res 2002;12:405-16.
    • (2002) Melanoma Res , vol.12 , pp. 405-416
    • Sturm, R.A.1
  • 21
    • 0033673154 scopus 로고    scopus 로고
    • The adenomatous polyposis coli (APC) tumour suppressor - Genetics, function and disease
    • Sieber OM, Tomlison IP, Lamlum H. The adenomatous polyposis coli (APC) tumour suppressor - genetics, function and disease. Mol Med Today 2000;6:462-9.
    • (2000) Mol Med Today , vol.6 , pp. 462-469
    • Sieber, O.M.1    Tomlison, I.P.2    Lamlum, H.3
  • 22
    • 0035081414 scopus 로고    scopus 로고
    • Update on genetic events in the pathogenesis of melanoma
    • Halachmi S, Gilchrest BA. Update on genetic events in the pathogenesis of melanoma. Curr Opin Oncol 2001;13:129-36.
    • (2001) Curr Opin Oncol , vol.13 , pp. 129-136
    • Halachmi, S.1    Gilchrest, B.A.2
  • 24
    • 0042743826 scopus 로고    scopus 로고
    • BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma
    • Dong J, Phelps RG, Qiao R i sur. BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma. Cancer Res 2003;63:3883-5.
    • (2003) Cancer Res , vol.63 , pp. 3883-3885
    • Dong, J.1    Phelps, R.G.2    Qiao, R.3
  • 25
    • 0037379794 scopus 로고    scopus 로고
    • ERK (MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38 (SAPK)
    • Aguirre-Ghiso JA, Estrada Y, Liu D, Ossowski L. ERK (MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38 (SAPK). Cancer Res 2003;63:1684-95.
    • (2003) Cancer Res , vol.63 , pp. 1684-1695
    • Aguirre-Ghiso, J.A.1    Estrada, Y.2    Liu, D.3    Ossowski, L.4
  • 26
    • 0037380925 scopus 로고    scopus 로고
    • Epigenetic inactivation of RAS association domain family protein 1 (RASSF1A) in malignant cutaneous melanoma
    • Spugnardi M, Tommasi S, Dammann R, Pfeifer GP, Hoon DS. Epigenetic inactivation of RAS association domain family protein 1 (RASSF1A) in malignant cutaneous melanoma. Cancer Res 2003;63:1639-43.
    • (2003) Cancer Res , vol.63 , pp. 1639-1643
    • Spugnardi, M.1    Tommasi, S.2    Dammann, R.3    Pfeifer, G.P.4    Hoon, D.S.5
  • 27
    • 0038456399 scopus 로고    scopus 로고
    • PTEN signaling pathways in melanoma
    • Wu H, Goel V, Haluska FG. PTEN signaling pathways in melanoma. Oncogene 2003;22:3113-22.
    • (2003) Oncogene , vol.22 , pp. 3113-3122
    • Wu, H.1    Goel, V.2    Haluska, F.G.3
  • 30
    • 4043121025 scopus 로고    scopus 로고
    • Genetic pathways to melanoma tumorigenesis
    • Hussein MR. Genetic pathways to melanoma tumorigenesis. J Clin Pathol 2004;57:797-801.
    • (2004) J Clin Pathol , vol.57 , pp. 797-801
    • Hussein, M.R.1
  • 31
    • 0027053755 scopus 로고
    • The putative melanoma tumor-suppressor gene on human chromosome 6q
    • Copeman MC. The putative melanoma tumor-suppressor gene on human chromosome 6q. Pathology 1992;24:307-9.
    • (1992) Pathology , vol.24 , pp. 307-309
    • Copeman, M.C.1
  • 32
    • 0028121279 scopus 로고
    • A cell cycle regulator potentially involved in genesis of many tumor types
    • Kamb A, Gruis NA, Weaver-Feldhaus J i sur. A cell cycle regulator potentially involved in genesis of many tumor types. Science 1994;264:436-40.
    • (1994) Science , vol.264 , pp. 436-440
    • Kamb, A.1    Gruis, N.A.2    Weaver-Feldhaus, J.3
  • 33
    • 0031993696 scopus 로고    scopus 로고
    • p16(INK4A)/CDKN2-The »melanoma gene«? Status of research and outlook
    • Bogenrieder T, Landthaler M, Stolz W. p16(INK4A)/CDKN2-the »melanoma gene«? Status of research and outlook. Hautarzt 1998;49:91-100.
    • (1998) Hautarzt , vol.49 , pp. 91-100
    • Bogenrieder, T.1    Landthaler, M.2    Stolz, W.3
  • 34
    • 0029587551 scopus 로고
    • Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
    • Quelle DE, Zindy F. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 1995;83:993-1000.
    • (1995) Cell , vol.83 , pp. 993-1000
    • Quelle, D.E.1    Zindy, F.2
  • 35
    • 0028100903 scopus 로고
    • Germline p16 mutations in familial melanoma
    • Hussussian C. Germline p16 mutations in familial melanoma. Nature Genet 1994;8:15-21.
    • (1994) Nature Genet , vol.8 , pp. 15-21
    • Hussussian, C.1
  • 37
    • 0033518889 scopus 로고    scopus 로고
    • CDKN2A variants in a population-based sample of Queensland families with melanoma
    • Aitken J, Welch J, Duffy D i sur. CDKN2A variants in a population-based sample of Queensland families with melanoma. J Natl Cancer Inst 1999;91:446-52.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 446-452
    • Aitken, J.1    Welch, J.2    Duffy, D.3
  • 38
    • 0042338505 scopus 로고    scopus 로고
    • Alterations in CDKN2A locus as potential indicator of melanoma predisposition in relatives of non-familial melanoma cases
    • Levanat S, Šitum M, Crnić I i sur. Alterations in CDKN2A locus as potential indicator of melanoma predisposition in relatives of non-familial melanoma cases. Croat Med J 2003;44:418-24.
    • (2003) Croat Med J , vol.44 , pp. 418-424
    • Levanat, S.1    Šitum, M.2    Crnić, I.3
  • 39
    • 0030917395 scopus 로고    scopus 로고
    • 16/CDKN2 and CDK4 gene mutations in sporadic melanoma development and progression
    • Piccinin S, Doglioni C, Maestro R i sur. 16/CDKN2 and CDK4 gene mutations in sporadic melanoma development and progression. Int J Cancer 1997;74:26-30.
    • (1997) Int J Cancer , vol.74 , pp. 26-30
    • Piccinin, S.1    Doglioni, C.2    Maestro, R.3
  • 40
    • 0031695202 scopus 로고    scopus 로고
    • Selective deletion of exon 1 beta of the p19ARF gene in metastatic melanoma cell lines
    • Kumar R, Sauroja I, Punnonen K, Jansen C, Hemminki K. Selective deletion of exon 1 beta of the p19ARF gene in metastatic melanoma cell lines. Genes Chromosomes Cancer 1998;23:273-7.
    • (1998) Genes Chromosomes Cancer , vol.23 , pp. 273-277
    • Kumar, R.1    Sauroja, I.2    Punnonen, K.3    Jansen, C.4    Hemminki, K.5
  • 41
    • 0035817722 scopus 로고    scopus 로고
    • A melanoma-associated germline mutation in exon 1 beta inactivates p14ARF
    • Rizos H, Puig S, Badenas C i sur. A melanoma-associated germline mutation in exon 1 beta inactivates p14ARF. Oncogene 2001;20:5543-7.
    • (2001) Oncogene , vol.20 , pp. 5543-5547
    • Rizos, H.1    Puig, S.2    Badenas, C.3
  • 42
    • 0027980180 scopus 로고
    • Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes
    • Demetrick DJ. Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes. Cytogenet Cell Genet 1994;66:72-4.
    • (1994) Cytogenet Cell Genet , vol.66 , pp. 72-74
    • Demetrick, D.J.1
  • 43
    • 6844226190 scopus 로고    scopus 로고
    • Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France: The French Familial Melanoma Study Group
    • Soufir N, Avril MF, Chompret A i sur. Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France: the French Familial Melanoma Study Group. Hum Molec Genet 1998;7:209-16.
    • (1998) Hum Molec Genet , vol.7 , pp. 209-216
    • Soufir, N.1    Avril, M.F.2    Chompret, A.3
  • 44
    • 0030838776 scopus 로고    scopus 로고
    • Complete scanning of the CDK4 gene by denaturing gradient gel electrophoresis: A novel missense mutation but low overall frequency of mutations in sporadic metastatic malignant melanoma
    • Guldberg P, Kirkin AF, Gronbaek K, thor Straten P, Ahrenkiel V, Zeuthen J. Complete scanning of the CDK4 gene by denaturing gradient gel electrophoresis: a novel missense mutation but low overall frequency of mutations in sporadic metastatic malignant melanoma. J Int J Cancer 1997; 72:780-3.
    • (1997) J Int J Cancer , vol.72 , pp. 780-783
    • Guldberg, P.1    Kirkin, A.F.2    Gronbaek, K.3    Thor Straten, P.4    Ahrenkiel, V.5    Zeuthen, J.6
  • 45
    • 0032784037 scopus 로고    scopus 로고
    • CDKN2A (P16(INK4a)) and CDK4 mutation analysis in 131 Australian melanoma probands: Effect of family history and multiple primary melanomas
    • Holland EA, Schmid H, Kefford RF, Mann GJ. CDKN2A (P16(INK4a)) and CDK4 mutation analysis in 131 Australian melanoma probands: effect of family history and multiple primary melanomas. Genes Chromosomes Cancer 1999;25:339-48.
    • (1999) Genes Chromosomes Cancer , vol.25 , pp. 339-348
    • Holland, E.A.1    Schmid, H.2    Kefford, R.F.3    Mann, G.J.4
  • 46
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 1993;366: 704-7.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 47
    • 0037941546 scopus 로고    scopus 로고
    • p16/cyclin-dependent kinase inhibitor 2A deficiency in human melanocyte senescence, apoptosis, and immortalization: Possible implications for melanoma progression
    • Sviderskaya EV, Gray-Schopfer VC, Hill SP i sur. p16/cyclin-dependent kinase inhibitor 2A deficiency in human melanocyte senescence, apoptosis, and immortalization: possible implications for melanoma progression. J Natl Cancer Inst 2003;95:723-32.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 723-732
    • Sviderskaya, E.V.1    Gray-Schopfer, V.C.2    Hill, S.P.3
  • 49
    • 0028091349 scopus 로고
    • Mapping of the gene encoding the melanocortin-1 (alpha-melanocyte stimulating hormone) receptor (MC1R) to human chromosome 16q24.3 by fluorescence in situ hybridization
    • Gantz I, Yamada T, Tashiro T i sur. Mapping of the gene encoding the melanocortin-1 (alpha-melanocyte stimulating hormone) receptor (MC1R) to human chromosome 16q24.3 by fluorescence in situ hybridization. Genomics 1994;19:394-5.
    • (1994) Genomics , vol.19 , pp. 394-395
    • Gantz, I.1    Yamada, T.2    Tashiro, T.3
  • 51
    • 0028786945 scopus 로고
    • Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans
    • Valverde P, Healy F, Jackson I, Rees JL, Thody AJ. Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans. Nature Genet 1995;11:328-30.
    • (1995) Nature Genet , vol.11 , pp. 328-330
    • Valverde, P.1    Healy, F.2    Jackson, I.3    Rees, J.L.4    Thody, A.J.5
  • 52
    • 0034712537 scopus 로고    scopus 로고
    • Melanocortin-1-receptor gene and sun sensitivity in individuals without red hair
    • Healy E, Flannagan N, Ray A i sur. Melanocortin-1-receptor gene and sun sensitivity in individuals without red hair. Lancet 2000;355:1072-3.
    • (2000) Lancet , vol.355 , pp. 1072-1073
    • Healy, E.1    Flannagan, N.2    Ray, A.3
  • 53
    • 7144254441 scopus 로고    scopus 로고
    • Melanocortin 1 receptor variants in an Irish population
    • Smith R, Healy E, Siddiqui S i sur. Melanocortin 1 receptor variants in an Irish population. J Invest Derm 1998;111:119-22.
    • (1998) J Invest Derm , vol.111 , pp. 119-122
    • Smith, R.1    Healy, E.2    Siddiqui, S.3
  • 54
    • 0034641860 scopus 로고    scopus 로고
    • Pleiotropic effects of the melanocortin 1 receptor (MC1R) gene on human pigmentation
    • Flanagan N, Healy E, Ray A i sur. Pleiotropic effects of the melanocortin 1 receptor (MC1R) gene on human pigmentation. Hum Mol Genet 2000;9:2531-7.
    • (2000) Hum Mol Genet , vol.9 , pp. 2531-2537
    • Flanagan, N.1    Healy, E.2    Ray, A.3
  • 55
    • 0033910271 scopus 로고    scopus 로고
    • Melanocortin-1 receptor polymorphisms and risk of melanoma: Is the association explained solely by pigmentation phenotype?
    • Palmer JS, Duffy DL, Box NF i sur. Melanocortin-1 receptor polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype? Am J Hum Genet 2000;66:176-86.
    • (2000) Am J Hum Genet , vol.66 , pp. 176-186
    • Palmer, J.S.1    Duffy, D.L.2    Box, N.F.3
  • 56
    • 0035422250 scopus 로고    scopus 로고
    • The melanocortin-1-receptor gene is the major freckle gene
    • Bastiaens M, ter Huurne J, Gruis N i sur. The melanocortin-1-receptor gene is the major freckle gene. Hum Mol Genet 2001;10:1701-8.
    • (2001) Hum Mol Genet , vol.10 , pp. 1701-1708
    • Bastiaens, M.1    Ter Huurne, J.2    Gruis, N.3
  • 57
    • 0034837773 scopus 로고    scopus 로고
    • MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations
    • Box NF, Duffy DL, Chen W i sur. MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations. Am J Hum Genet 2001;69:765-73.
    • (2001) Am J Hum Genet , vol.69 , pp. 765-773
    • Box, N.F.1    Duffy, D.L.2    Chen, W.3
  • 58
    • 0038795172 scopus 로고    scopus 로고
    • Genetics of melanoma predisposition
    • Hayward NK. Genetics of melanoma predisposition. Oncogene 2003;22: 3053-62.
    • (2003) Oncogene , vol.22 , pp. 3053-3062
    • Hayward, N.K.1
  • 60
    • 0037633747 scopus 로고    scopus 로고
    • Expression of c-met tyrosine kinase receptor is biologically and prognostically relevant for primary cutaneous malignant melanomas
    • Cruz J, Reis-Filho JS, Silva P, Lopes JM. Expression of c-met tyrosine kinase receptor is biologically and prognostically relevant for primary cutaneous malignant melanomas. Oncology 2003;65:72-82.
    • (2003) Oncology , vol.65 , pp. 72-82
    • Cruz, J.1    Reis-Filho, J.S.2    Silva, P.3    Lopes, J.M.4
  • 61
    • 0037779427 scopus 로고    scopus 로고
    • Repression of TGF-beta signaling by the oncogenic protein SKI in human melanomas: Consequences for proliferation, survival, and metastasis
    • Medrano EE. Repression of TGF-beta signaling by the oncogenic protein SKI in human melanomas: consequences for proliferation, survival, and metastasis. Oncogene 2003;22:3123-9.
    • (2003) Oncogene , vol.22 , pp. 3123-3129
    • Medrano, E.E.1
  • 62
    • 0037278743 scopus 로고    scopus 로고
    • Transcriptional regulation of metastasis-related genes in human melanoma
    • Nyormoi O, Bar-Eli M. Transcriptional regulation of metastasis-related genes in human melanoma. Clin Exp Metastasis 2003;20:251-63.
    • (2003) Clin Exp Metastasis , vol.20 , pp. 251-263
    • Nyormoi, O.1    Bar-Eli, M.2
  • 63
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson GL, Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002;298:1911-2.
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 64
    • 0028891865 scopus 로고
    • Analysis of ras mutations in human melanocytic lesions: Activation of the ras gene seems to be associated with the nodular type of human malignant melanoma
    • Jafari M, Papp T, Kirchner S i sur. Analysis of ras mutations in human melanocytic lesions: activation of the ras gene seems to be associated with the nodular type of human malignant melanoma. J Cancer Res Clin Oncol 1995;121:23-30.
    • (1995) J Cancer Res Clin Oncol , vol.121 , pp. 23-30
    • Jafari, M.1    Papp, T.2    Kirchner, S.3
  • 65
    • 0034072726 scopus 로고    scopus 로고
    • Gene amplifications characterize acral melanoma and permit the detection of occult tumor cells in the surrounding skin
    • Bastian BC, Kashani-Sabet M, Hamm H i sur. Gene amplifications characterize acral melanoma and permit the detection of occult tumor cells in the surrounding skin. Cancer Res 2000;60:1968-73.
    • (2000) Cancer Res , vol.60 , pp. 1968-1973
    • Bastian, B.C.1    Kashani-Sabet, M.2    Hamm, H.3
  • 67
    • 0037228055 scopus 로고    scopus 로고
    • High frequency of BRAF mutations in nevi
    • Pollock PM, Harper UL, Hansen KS i sur. High frequency of BRAF mutations in nevi. Nat Genet 2003;33:19-20.
    • (2003) Nat Genet , vol.33 , pp. 19-20
    • Pollock, P.M.1    Harper, U.L.2    Hansen, K.S.3
  • 68
    • 0025805633 scopus 로고
    • Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product
    • Bottaro DP, Rubin JS, Faletto DL i sur. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 1991;251:802-4
    • (1991) Science , vol.251 , pp. 802-804
    • Bottaro, D.P.1    Rubin, J.S.2    Faletto, D.L.3
  • 69
    • 0035819040 scopus 로고    scopus 로고
    • Downregulation of E-cadherin and desmoglein 1 by autocrine hepatocyte growth factor during melanoma development
    • Li G, Schaider H, Satyamoorthy K, Hanakawa Y, Hashimoto K, Herlyn M. Downregulation of E-cadherin and desmoglein 1 by autocrine hepatocyte growth factor during melanoma development. Oncogene 2001;20: 8125-35.
    • (2001) Oncogene , vol.20 , pp. 8125-8135
    • Li, G.1    Schaider, H.2    Satyamoorthy, K.3    Hanakawa, Y.4    Hashimoto, K.5    Herlyn, M.6
  • 70
    • 0027382172 scopus 로고
    • Expression of the c-Met/HGF receptor in human melanocytic neoplasms: Demonstration of the relationship to malignant melanoma tumour progression
    • Natali PG, Nicotra MR, Di Renzo MF i sur. Expression of the c-Met/HGF receptor in human melanocytic neoplasms: demonstration of the relationship to malignant melanoma tumour progression. Br J Cancer 1993; 68:746-50.
    • (1993) Br J Cancer , vol.68 , pp. 746-750
    • Natali, P.G.1    Nicotra, M.R.2    Di Renzo, M.F.3
  • 71
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li J, Yen C, Liaw D i sur. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997; 275:1943-7.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3
  • 72
    • 0030777104 scopus 로고    scopus 로고
    • Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma
    • Guldberg P, Thor Straten P, Birck A, Ahrenkiel V, Kirkin AF, Zeuthen J. Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. Cancer Res 1997;57:3660-3.
    • (1997) Cancer Res , vol.57 , pp. 3660-3663
    • Guldberg, P.1    Thor Straten, P.2    Birck, A.3    Ahrenkiel, V.4    Kirkin, A.F.5    Zeuthen, J.6
  • 73
    • 14444269482 scopus 로고    scopus 로고
    • MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines
    • Teng DH, Hu R, Lin H i sur. MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines. Cancer Res 1997;57:5221-5.
    • (1997) Cancer Res , vol.57 , pp. 5221-5225
    • Teng, D.H.1    Hu, R.2    Lin, H.3
  • 74
    • 3442894137 scopus 로고    scopus 로고
    • Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas
    • Hoek K, Rimm DL, Williams KR i sur. Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas. Cancer Res 2004;64:5270-82.
    • (2004) Cancer Res , vol.64 , pp. 5270-5282
    • Hoek, K.1    Rimm, D.L.2    Williams, K.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.