Serial cerebrospinal fluid sampling in a rat model to study drug uptake from the nasal cavity

Journal of Neuroscience Methods

Volumn 116, Issue 1, 2002, Pages 99-107

  Van Den Berg, Mascha P ^a   Romeijn, Stefan G ^a   Verhoef, J Coos ^a   Merkus, Frans W H M ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Cisternal puncture method; Hydrocortisone; Intranasal delivery; Nose to brain transport; Rat; Serial CSF sampling

Indexed keywords

HYDROCORTISONE;

ACCURACY; ARTICLE; ATLANTOOCCIPITAL JOINT; BLOOD SAMPLING; CANNULATION; CEREBROSPINAL FLUID ANALYSIS; CISTERNA MAGNA; CONTROLLED STUDY; DRUG ABSORPTION; DRUG UPTAKE; HEAD POSITION; MALE; MEMBRANE; NONHUMAN; NOSE CAVITY; PRIORITY JOURNAL; PUNCTURE; RAT; STANDING; SUPINE POSITION;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; CISTERNA MAGNA; HYDROCORTISONE; MALE; NASAL CAVITY; POSTURE; RATS; RATS, WISTAR; SPINAL PUNCTURE; STEREOTAXIC TECHNIQUES;

EID: 0037197789     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0270(02)00033-X     Document Type: Article

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