The distribution of local anesthetics into the CSF following intranasal administration

International Journal of Pharmaceutics

Volumn 168, Issue 2, 1998, Pages 137-145

  Chou, Kang Jye ^a   Donovan, Maureen D ^a  

^a Div of Pharmaceut Coll of P   (United States)

Author keywords

Bloo brain barrier; CNS disposition; CSF; Local anesthetics; Nasal administration

Indexed keywords

BUPIVACAINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; PROCAINE; TETRACAINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; CISTERNA MAGNA; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG DISPOSITION; DRUG TISSUE LEVEL; DRUG TRANSPORT; FEMORAL ARTERY; INTRAARTERIAL DRUG ADMINISTRATION; INTRANASAL DRUG ADMINISTRATION; LIPOPHILICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0032527021     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(98)00061-1     Document Type: Article

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