An orthotopic model of lung cancer to analyze primary and metastatic NSCLC growth in integrin α1-null mice

Clinical and Experimental Metastasis

Volumn 22, Issue 2, 2005, Pages 185-193

  Chen, Xiwu ^a   Su, Yan ^a   Fingleton, Barbara ^b   Acuff, Heath ^b   Matrisian, Lynn M ^b   Zent, Roy ^a,b,c   Pozzi, Ambra ^a,b,c  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Angiogenesis; Angiostatin; Doxycyline; Lung cancer; Matrix metalloproteinases; Orthotopic

Indexed keywords

ALPHA1 INTEGRIN; GELATINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; METASTASIS; MOUSE; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; THEORETICAL MODEL; TUMOR CELL; TUMOR VASCULARIZATION; WILD TYPE;

ANIMALS; CARCINOMA, NON-SMALL-CELL LUNG; DISEASE PROGRESSION; HUMANS; INTEGRIN ALPHA1; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 9; MICE; MICE, KNOCKOUT; MICE, NUDE; MODELS, THEORETICAL; NEOPLASM METASTASIS; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC;

EID: 23944476344     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10585-005-7453-8     Document Type: Article

References (38)

1. A Jemal A Thomas T Murray 2002 Cancer statistics, 2002 Cancer J Clin 52 23 47
2. LA Cornelius LC Nehring E Harding 1998 Matrix metalloproteinases generate angiostatin: Effects on neovascularization J Immunol 161 6845 52
3. QX Sang 1998 Complex role of matrix metalloproteinases in angiogenesis Cell Res 8 171 7
4. E Petitclerc A Boutaud A Prestayko 2000 New functions for non-collagenous domains of human collagen type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo J Biol Chem 275 8051 61
5. Y Hamano M Zeisberg H Sugimoto 2003 Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin Cancer Cell 3 589 601
6. A Pozzi PE Moberg LA Miles 2000 Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization Proc Natl Acad Sci USA 97 2202 7
7. A Pozzi WF LeVine HA Gardner 2002 Low plasma levels of matrix metalloproteinase 9 permit increased tumor angiogenesis Oncogene 21 272 81
8. BP Himelstein R Canete-Soler EJ Bernhard 1994 Metalloproteinases in tumor progression: The contribution of MMP-9 Invasion Metastasis 14 246 58
9. ME Kupferman ME Fini WJ Muller 2000 Matrix metalloproteinase 9 promoter activity is induced coincident with invasion during tumor progression Am J Pathol 157 1777 83
10. N Hiraoka E Allen IJ Apel 1998 Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins Cell 95 365 77
11. G Bergers R Brekken G McMahon 2000 Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis Nat Cell Biol 2 737 44
12. CF Chantrain H Shimada S Jodele 2004 Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment Cancer Res 64 1675 86
13. Pozzi A. Lung Cancer Principles and Practice. 3: Lippincott Williams & Wilkins 2005; 178-86
14. R Hoffman 2002 Green fluorescent protein imaging of tumour growth, metastasis, and angiogenesis in mouse models Lancet Oncol 3 546 56
15. N El Hilali N Rubio M Martinez-Villacampa 2002 Combined noninvasive imaging and luminometric quantification of luciferase-labeled human prostate tumors and metastases Lab Invest 82 1563 71
16. Y Doki K Murakami T Yamaura 1999 Mediastinal lymph node metastasis model by orthotopic intrapulmonary implantation of Lewis lung carcinoma cells in mice Br J Cancer 79 1121 26
17. USA BC. Bayer Halts Clinical Trials Evaluating MMPI. http:www.bayerus. com/new/1999/09.99ud.html. Release date: Sept. 24, 1999.
18. Agouron. Pfizer Discontinues Phase III Trials of Prinomastat in Advanced Cancers But Continues Multiple Phase II Trials. http://www.agouron.com/Pages/ press_releases/pr080400.html. 2000.
19. S Zucker RM Lysik MH Zarrabi 1992 Type IV collagenase/gelatinase (MMP-2) is not increased in plasma of patients with cancer Cancer Epidemiol Biomarkers Prev 1 475 9
20. Y Cao MS O'Reilly B Marshall 1998 Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases J Clin Invest 101 1055 63
21. O Peyruchaud CM Serre R NicAmhlaoibh 2003 Angiostatin inhibits bone metastasis formation in nude mice through a direct anti-osteoclastic activity J Biol Chem 278 45826 32
22. M Volm J Mattern R Koomagi 2000 Angiostatin expression in non-small cell lung cancer Clin Cancer Res 6 3236 40
23. G Fontanini M Lucchi S Vignati 1997 Angiogenesis as a prognostic indicator of survival in non-small-cell lung carcinoma: A prospective study J Natl Cancer Inst 89 881 6
24. Y Maeshima A Sudhakar JC Lively 2002 Tumstatin, an endothelial cell-specific inhibitor of protein synthesis Science 295 140 3
25. GD Kamphaus PC Colorado DJ Panka 2000 Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth J Biol Chem 275 1209 15
26. MS O'Reilly T Boehm Y Shing 1997 Endostatin: An endogenous inhibitor of angiogenesis and tumor growth Cell 88 277 85
27. PC Colorado A Torre G Kamphaus 2000 Anti-angiogenic cues from vascular basement membrane collagen Cancer Res 60 2520 26
28. R Kurdow AS Boehle M Ruhnke 2003 Retroviral endostatin gene transfer inhibits growth of human lung cancer in a murine orthotopic xenotransplant model Langenbecks Arch Surg 388 401 5
29. HC Lin JH Chang S Jain 2001 Matrilysin cleavage of corneal collagen type XVIII NC1 domain and generation of a 28-kDa fragment Invest Ophthalmol Vis Sci 42 2517 24
30. A Pozzi KK Wary FG Giancotti 1998 Integrin alpha1beta1 mediates a unique collagen-dependent proliferation pathway in vivo J Cell Biol 142 587 94
31. SE Dunsmore DE Rannels 1996 Extracellular matrix biology in the lung Am J Physiol 270 L3 27
32. T Sorsa NS Ramamurthy AT Vernillo 1998 Functional sites of chemically modified tetracyclines: Inhibition of the oxidative activation of human neutrophil and chicken osteoclast pro-matrix metalloproteinases J Rheumatol 25 975 82
33. GN Smith Jr. EA Mickler KA Hasty 1999 Specificity of inhibition of matrix metalloproteinase activity by doxycycline: Relationship to structure of the enzyme Arthritis Rheum 42 1140 6
34. RE Seftor EA Seftor JE De Larco 1998 Chemically modified tetracyclines inhibit human melanoma cell invasion and metastasis Clin Exp Metast 16 217 25
35. ME Ryan S Ramamurthy LM Golub 1996 Matrix metalloproteinases and their inhibition in periodontal treatment Curr Opin Periodontol 3 85 96
36. S Ylisirnio M Hoyhtya T Turpeenniemi-Hujanen 2000 Serum matrix metalloproteinases -2, -9 and tissue inhibitors of metalloproteinases -1, -2 in lung cancer - TIMP-1 as a prognostic marker Anticancer Res 20 1311 6
37. L Ferrigan WA Wallace 2004 Predicting non-small cell lung cancer expression of epidermal growth factor receptor and matrix metalloproteinase 9 from immunohistochemical staining of diagnostic biopsy samples Eur J Cancer 40 1589 92
38. Chen X, Su Y, Fingleton B et al. Increased plasma MMP9 in integrin alpha1-null mice enhances lung metastasis of colon carcinoma cells. Int J Cancer 2005.